Portal de recerca
CARACTERIZACION METABOLOMICA DE LA MIOCARDIOPATIA ARRITMOGENICA
Dades bàsiques
- Codi Financador:
- 2013_0126_CRC_METABOLOMICA_ZORIO
- Any inicial:
- 2013
- Any final:
- 2014
Objectius del projecte
FINALIZADO
Documents
- No hi ha documents
Participants
Grups d'Investigació
Finançadors
Resultats del Projecte
A new mutation in the ryanodine receptor 2 gene (RYR2 C2277R) as a cause catecholaminergic polymorphic ventricular tachycardia.
Letter. 10.1016/j.rec.2014.07.022. 2015
A NOVEL TISSUE MICRORNA SIGNATURE FOR ARRHYTHMOGENIC CARDIOMYOPATHY
Zorio, E.; (...); Medina, P.
Article. 10.1016/S0049-3848(14)50269-1. 2014
A novel tissue microRNA signature for arrythmogenic cardiomyopathy.
Zorio, E; (...); Medina, P.
Article. 2014
An International Multi-Center Cohort Study on ß-blockers for the Treatment of Symptomatic Children with Catecholaminergic Polymorphic Ventricular Tachycardia.
Peltenburg PJ; (...); Wilde AAM
Article. 10.1161/CIRCULATIONAHA.121.056018. 2022
Arrhythmogenic cardiomyopathy with left ventricular involvement versus ischemic heart disease: lessons learned from the family study and the reviewed autopsy of a young male.
Article. 10.1080/20961790.2019.1616247. 2019
Association of Left Ventricular Systolic Dysfunction Among Carriers of Truncating Variants in Filamin C With Frequent Ventricular Arrhythmia and End-stage Heart Failure
Akhtar, MM; (...); European Genetic Cardiomyopathies
Article. 10.1001/jamacardio.2021.1106. 2021
Cadaveric Adipose-Derived Stem Cells for Regenerative Medicine and Research.
Milian, Lara; (...); Zorio, Esther
Article. 10.3390/ijms242115696. 2023
Cardiac phenotype in glycogen storage disease type XV: a rare cardiomyopathy to bear in mind.
Mancheño N; (...); Zorio, Esther
Letter. 10.1016/j.recesp.2020.05.033. 2021
Cardiomyopathy associated with primary carnitine deficiency in adults: lack of complete response in patients with delayed treatment initiation
Cervera, Borja Guerrero; (...); Zorio, Esther
Letter. 10.1016/j.recesp.2023.08.011. 2024
Cardiomyopathy associated with primary carnitine deficiency in adults: lack of complete response in patients with delayed treatment initiation.
Guerrero Cervera B; (...); Zorio E
Case Reports. 10.1016/j.rec.2023.08.011. 2024
Case Report: Probable Myocarditis After Covid-19 mRNA Vaccine in a Patient With Arrhythmogenic Left Ventricular Cardiomyopathy.
Alania-Torres, Edgardo; (...); Valle-Munoz, Alfonso
Case Reports. 10.3389/fcvm.2021.759119. 2021
Classification model based on strain measurements to identify patients with arrhythmogenic cardiomyopathy with left ventricular involvement.
Vives-Gilabert Y; (...); Castells F
Article. 10.1016/j.cmpb.2019.105296. 2020
Clinical and molecular characterization of a group of Spanish and German patients with Noonan syndrome
Lopez Gonzalez, Vanesa; (...); Guillen-Navarro, Encarna
Meeting Abstract. 2022
Clinical characteristics and determinants of the phenotype in TMEM43 arrhythmogenic right ventricular cardiomyopathy type 5.
Dominguez F; (...); Garcia-Pavia P
Article. 10.1016/j.hrthm.2020.01.035. 2020
Clinical Features and Natural History of PRKAG2 Variant Cardiac Glycogenosis
Lopez-Sainz, A; (...); European Genetic Cardiomyopathies
Article. 10.1016/j.jacc.2020.05.029. 2020
Clinical Findings and Prognosis of Danon Disease. An Analysis of the Spanish Multicenter Danon Registry
Lopez-Sainz, A; (...); Garcia-Pavia, P
Article. 10.1016/j.rec.2018.04.035. 2019
Clinical Profile of Cardiac Involvement in Danon Disease: A Multicenter European Registry.
Lotan D; (...); Arad M
Article. 10.1161/CIRCGEN.120.003117. 2020
Clinical Risk Prediction in Patients With Left Ventricular Myocardial Noncompaction
Casas, G; (...); Rodriguez-Palomares, JF
Article. 10.1016/j.jacc.2021.06.016. 2021
Clinical, echocardiographic and analytical patterns of biomarkers in cardiac amyloidosis; a real-world analysis.
Lopez Vilella, R. Raquel; (...); Almenar Bonet, L.
Meeting Abstract. 2024
Comparison between hiPS-CM from RyR2-R420Q CPVT Patients and KI Mice Bearing the Same Mutation
Yin, LH; (...); Gomez, AM
Meeting Abstract. 2020
comprehensive CMR analysis improves risk stratification in left ventricular noncompaction
Casas, G.; (...); Rodriguez-Palomares, J. F.
Meeting Abstract. 2023
Characterization of Ca2+ handling in induced-pluripotent cardiomyocytes from a CPVT family harbouring the RyR2(R420Q) mutation
Blasco, Almudena Val; (...); Gomez, Ana M.
Meeting Abstract. 2022
Characterization of hereditary transthyretin cardiac amyloidosis in Spain.
Alvarez Rubio, Jorge; (...); AC-TTRv-Spain Investigator Group
Article. 10.1016/j.rec.2021.07.020. 2022
Deregulated hepatic microRNAs underlie the association between non-alcoholic fatty liver disease and coronary artery disease
Braza-Boils A; (...); Zorio E
Article. 10.1111/liv.13097. 2016
Diagnostic Approach to Unexplained Cardiac Arrest (from the FIVI-Gen Study)
Jimenez-Jaimez, J; (...); Tercedor, L
Article. 10.1016/j.amjcard.2015.06.030. 2015
Diagnostic yield of molecular autopsy in patients with sudden arrhythmic death syndrome using targeted exome sequencing
Nunn LM; (...); Lambiase PD
Article. 10.1093/europace/euv285. 2016
Direct oral anticoagulants in patients with hypertrophic cardiomyopathy and atrial fibrillation
Dominguez, F; (...); Garcia-Pavia, P
Article. 10.1016/j.ijcard.2017.08.010. 2017
Disparate molecular mechanisms in cardiac ryanodine receptor channelopathies
Zhang, Yadan; (...); Zissimopoulos, Spyros
Article. 10.3389/fmolb.2024.1505698. 2024
Dyssynchrony Assessment in Arrhythmogenic Cardiomyopathy With Left Ventricular Involvement
Vives-Gilabert, Y; (...); Castells, F
Proceedings Paper. 10.22489/CinC.2018.073. 2018
Electrocardiographic findings in patients with arrhythmogenic cardiomyopathy and right bundle branch block ventricular tachycardia.
Laredo, Mikael; (...); Belhassen, Bernard
Article. 10.1093/europace/euac267. 2023
Electrophysiological Phenotype-Genotype Study of Sustained Monomorphic Ventricular Tachycardia in Inherited, High Arrhythmic Risk, Left Ventricular Cardiomyopathy.
Cabrera-Borrego, Eva; (...); Jimenez-Jaimez, Juan
Article. 10.1161/CIRCEP.124.013145. 2024
Extracellular Kir2.1(C122Y) Mutant Upsets Kir2.1-PIP(2) Bonds and Is Arrhythmogenic in Andersen-Tawil Syndrome.
Cruz FM; (...); Jalife J
Article. 10.1161/CIRCRESAHA.123.323895. 2024
Facts and Gaps in Exercise Influence on Arrhythmogenic Cardiomyopathy: New Insights From a Meta-Analysis Approach.
Martínez-Solé J; (...); Zorio E
Review. 10.3389/fcvm.2021.702560. 2021
Familial left ventricular noncompaction associated with a novel mutation in the alpha-cardiac actin gene.
Rodríguez-Serrano M; (...); Zorio E
Letter. 10.1016/j.rec.2014.05.015. 2014
Family Sudden Death Risk-Assessment Unit: Experience at the Valencian Community
Blasco, JG, Macian, II, Grima, EZ
Editorial Material. 2017
Filamin C variants are associated with a distinctive clinical and immunohistochemical arrhythmogenic cardiomyopathy phenotype.
Hall CL; (...); McKenna WJ
Article. 10.1016/j.ijcard.2019.09.048. 2020
Flecainide Is Associated With a Lower Incidence of Arrhythmic Events in a Large Cohort of Patients With Catecholaminergic Polymorphic Ventricular Tachycardia.
Bergeman, Auke T.; (...); van der Werf, Christian
Article. 10.1161/CIRCULATIONAHA.123.064786. 2023
Follow-up and prognosis of HCM.
Dominguez, Fernando; (...); Zorio, Esther
Article. 10.21542/gcsp.2018.33. 2018
Formin Homology 2 Domain Containing 3 (FHOD3) Is a Genetic Basis for Hypertrophic Cardiomyopathy
Ochoa, JP; (...); Monserrat, L
Article. 10.1016/j.jacc.2018.10.001. 2018
Functional Effects of the RyR(2)(R420Q) Catecholaminergic Ventricular Polymorphic Tachycardia in Mouse Cardiomyocytes
Rizzetto, R; (...); Gomez, AM
Meeting Abstract. 10.1016/j.bpj.2016.11.551. 2017
Haplotypes of the endothelial protein C receptor gene and circulating protein C levels
Martos, L.; (...); Medina, P.
Article. 2013
Hereditary transthyretin amyloidosis caused by the Val142Ile variant in Spain.
de Frutos, Fernando; (...); Gonzalez-Costello, Jose
Article. 10.1016/j.rec.2024.12.012. 2025
Hypertrophic cardiomyopathy due to truncating variants in myosin binding protein C: a Spanish cohort
Melendo-Viu, Maria; (...); Palomino Doza, Julian A.
Article. 10.1136/openhrt-2024-002891. 2024
Identification and validation of plasma micrornas involved in venous and arterial thrombosis
Ramon, L. A.; (...); Navarro, S.
Meeting Abstract. 2015
IDENTIFICATION OF A MICRORNA PROFILE RELATED TO HYPERTROPHIC CARDIOMYOPATHY
Plana, E.; (...); Medina, P.
Meeting Abstract. 10.1016/S0049-3848(14)50064-3. 2014
Identification of a microRNA profile related to hypertrophic cardiomyopathy. PUBLICACION: THROMBOSIS RESEARCH.
Plana, E; (...); Medina, P.
Article. 2014
IDENTIFICATION OF A PLASMA MICRORNAS PROFILE INVOLVED IN ARTERIAL THROMBOSIS
Navarro, S.; (...); Espana, F.
Meeting Abstract. 10.1016/S0049-3848(14)50273-3. 2014
Impact of SARS-CoV-2 infection in patients with cardiac amyloidosis: Results of a multicentre registry.
Larrañaga-Moreira JM; (...); Barriales-Villa R
Article. 10.1016/j.medcli.2023.06.025. 2023
Impact of SARS-Cov-2 infection in patients with hypertrophic cardiomyopathy: results of an international multicentre registry
Gimeno, Juan R.; (...); Lakdawala, Neal K.
Article. 10.1002/ehf2.13964. 2022
Impaired Binding to Junctophilin-2 and Nanostructural Alteration in CPVT Mutation
Yin L; (...); Gómez AM
Article. 10.1161/CIRCRESAHA.121.319094. 2021
Importance of genotype for risk stratification in arrhythmogenic right ventricular cardiomyopathy using the 2019 ARVC risk calculator
Protonotarios, Alexandros; (...); Elliott, Perry M.
Article. 10.1093/eurheartj/ehac235. 2022
Left ventricular ejection fraction decline and cardiovascular events in suspected cardiomyopathy with excessive trabeculation: toward precision medicine.
Casas, Guillem; (...); Rodriguez-Palomares, Jose F
Article. 10.1016/j.rec.2025.01.011. 2025
Left ventricular myocardial dysfunction in arrhythmogenic cardiomyopathy with left ventricular involvement: A door to improving diagnosis
Vives-Gilabert, Y; (...); Zorio, E
Article. 10.1016/j.ijcard.2018.09.024. 2019
Long term outcomes in left ventricular non-compaction
Casas, G; (...); Rodriguez-Palomares, JF
Meeting Abstract. 2020
Long-term prognosis of women with Brugada syndrome and electrophysiological study.
Rodríguez-Mañero M; (...); Arbelo E
Article. 10.1016/j.hrthm.2020.12.020. 2021
Mechanism of Sinoatrial Node Dysfunction in a RyR(2)R420Q Mouse Model Ofcatecholaminergic Polymorphic Ventricular Tachycardia
Wang, YY; (...); Gomez, AM
Meeting Abstract. 10.1016/j.bpj.2016.11.2924. 2017
MICRORNA EXPRESSION PROFILE IN EPICARDIAL FAT IN SUDDEN CARDIAC DEATH FROM CORONARY ARTERY DISEASE
Braza-Boils, A.; (...); Zorio, E.
Article. 2014
Myocardial Extracellular Volume Is Not Associated With Malignant Ventricular Arrhythmias in High-risk Hypertrophic Cardiomyopathy.
Mirelis JG; (...); Ibáñez B
Article. 10.1016/j.rec.2017.01.026. 2017
Natural History and Risk Stratification in Andersen-Tawil Syndrome Type 1
Mazzanti, A; (...); Priori, SG
Article. 10.1016/j.jacc.2020.02.033. 2020
Natural History of MYH7-related Dilated Cardiomyopathy.
de Frutos, Fernando; (...); Garcia-Pavia, Pablo
Article. 10.1016/j.jacc.2022.07.023. 2022
New ECG biomarkers and sex-stratified models for the detection of Arrhythmogenic Cardiomyopathy with left ventricular involvement
Jimenez-Serrano, Santiago; (...); Castells, Francisco
Article. 10.1016/j.bspc.2024.107224. 2025
Non Coding RNAs as Regulators of Wnt/ß-Catenin and Hippo Pathways in Arrhythmogenic Cardiomyopathy
Piquer-Gil, Marina; (...); Zorio, Esther
Review. 10.3390/biomedicines10102619. 2022
Non-ventricular, Clinical, and Functional Features of the RyR2(R420Q) Mutation Causing Catecholaminergic Polymorphic Ventricular Tachycardia.
Domingo, D; (...); Zorio, E
Article. 10.1016/j.rec.2014.04.023. 2015
Novel insights on Andersen-Tawil syndrome type 1
Mazzanti, A; (...); ATS1 Int Res Grp
Meeting Abstract. 2020
Penetrance of Dilated Cardiomyopathy in Genotype-Positive Relatives.
Cabrera-Romero E; (...); Garcia-Pavia P
Article. 10.1016/j.jacc.2024.02.036. 2024
Phenotype and Clinical Outcomes in Desmin-Related Arrhythmogenic Cardiomyopathy.
Bermudez-Jimenez FJ; (...); Jimenez-Jaimez J
Article. 10.1016/j.jacep.2024.02.031. 2024
Phenotypic Patterns of Cardiomyopathy Caused by Mutations in the Desmin Gene. A Clinical and Genetic Study in Two Inherited Heart Disease Units.
Ripoll-Vera, T; (...); Cremer, D
Letter. 10.1016/j.rec.2015.07.007. 2015
Plan of Action for Inherited Cardiovascular Diseases: Synthesis of Recommendations and Action Algorithms.
Barriales-Villa, R; (...); Garcia-Pavia, P
Article. 10.1016/j.rec.2015.11.029. 2016
Polymorphisms in ACE, ACE2, AGTR1 genes and severity of COVID-19 disease.
Sabater Molina, Maria; (...); Gimeno Blanes, Juan R.
Article. 10.1371/journal.pone.0263140. 2022
Postmortem genetic testing should be recommended in sudden cardiac death cases due to thoracic aortic dissection
Gago-Diaz, M; (...); Brion, M
Article. 10.1007/s00414-017-1583-9. 2017
POT1 and Damage Response Malfunction Trigger Acquisition of Somatic Activating Mutations in the VEGF Pathway in Cardiac Angiosarcomas.
Calvete O; (...); Benitez J
Article. 10.1161/JAHA.119.012875. 2019
Predictors of adverse cardiovascular events in patients with truncating variants in the filamin c (flnc) gene
Akhtar, M.; (...); Elliott, P. M.
Meeting Abstract. 2019
Predictors of systemic embolisms in a large cohort of left ventricular noncompaction patients
Casas, G.; (...); Rodriguez-Palomares, J. F.
Meeting Abstract. 2019
Pregnancy in women with dilated cardiomyopathy genetic variants.
Restrepo-Córdoba MA; (...); García-Pavía P
Article. 10.1016/j.rec.2024.04.002. 2024
Prognosis of left ventricular noncompaction with preserved ejection fraction
Casas, G.; (...); Rodriguez-Palomares, J. F.
Meeting Abstract. 2021
Psychosocial and adaptation factors in relatives of patients who died of sudden cardiac death
Rubio, AS; (...); Martin, CPB
Article. 2017
Ranolazine as an Alternative Therapy to Flecainide for SCN5A V411M Long QT Syndrome Type 3 Patients.
Cano J; (...); Romero L
Article. 10.3389/fphar.2020.580481. 2020
Renin-angiotensin system polymorphisms as potential modifier in COVID-19 outcome
Sabater Molina, Maria; (...); Gimeno Blanes, Juan Ramon
Meeting Abstract. 2022
RNA sequencing-based transcriptome profiling of cardiac tissue implicates novel putative disease mechanisms in FLNC-associated arrhythmogenic cardiomyopathy.
Hall CL; (...); Syrris P
Article. 10.1016/j.ijcard.2019.12.002. 2020
Role of microRNAs associated with non-alcoholic fatty liver disease in sudden cardiac death from coronary artery disease
Braza-Boils, A.; (...); Zorio, E.
Meeting Abstract. 10.1093/cvr/cvu082.6. 2014
ROLE OF THE MIRNAS OF PLATELETS IN THE EPICARDIAL ADIPOSE TISSUE OF PATIENTS WITH CORONARY DISEASE
Zorio, E.; (...); Braza-Boils, A.
Meeting Abstract. 2019
RyR(2)(R420Q) catecholaminergic polymorphic ventricular tachycardia mutation induces bradycardia by disturbing the coupled clock pacemaker mechanism
Wang, YY; (...); Gomez, AM
Article. 10.1172/jci.insight.91872. 2017
Sensitivity and negative predictive value of treadmill exercise stress testing for the diagnosis of catecholaminergic polymorphic ventricular tachycardia. Response.
Domingo, D; (...); Zorio, E
Letter. 10.1016/j.rec.2015.02.011. 2015
Simulation of the effects of flecainide and ranolazine under LQTS type 3 produced by the heterozygous SCN5A V411M mutant
Garcia, JC; (...); Perez, LR
Meeting Abstract. 10.1016/j.vascn.2020.106720. 2020
Study and prevention of sudden infant death: An experience in the Valencian community
Blasco, AM; (...); Grima, EZ
Article. 2017
Study of New Criteria Based on Eigenvalue Decomposition to Assist Arrhythmogenic Cardiomyopathy Diagnosis
Jimenez-Serrano, S; (...); Castells, F
Proceedings Paper. 2016
The EP300/TP53 pathway, a suppressor of the Hippo and canonical WNT pathways, is activated in human hearts with arrhythmogenic cardiomyopathy in the absence of overt heart failure.
Rouhi L; (...); Marian AJ
Article. 10.1093/cvr/cvab197. 2021
The genetic background of left ventricular hypertrabeculation/noncompaction remains vague. Response.
Rodríguez-Serrano M; (...); Zorio E
Letter. 10.1016/j.rec.2014.10.001. 2015
The prevalence of left and right bundle branch block morphology ventricular tachycardia amongst patients with arrhythmogenic cardiomyopathy and sustained ventricular tachycardia: insights from the European Survey on Arrhythmogenic Cardiomyopathy.
Belhassen, Bernard; (...); Milman, Anat
Article. 10.1093/europace/euab190. 2021
The RyR2(R420Q) Mutation Triggers Catecholaminergic Polymorphic Ventricular Tachycardia in Mouse Cardiomyocytes via SR Calcium Loading
Fernandez-Tenorio, M; (...); Niggli, E
Meeting Abstract. 2018
The RyR2R420Q+/- Mutation Triggers Arrhythmogenic Ca2+Events in Mouse Cardiomyocyte
Lopez, R; (...); Nigglil, E
Meeting Abstract. 2019
Thickness and an Altered miRNA Expression in the Epicardial Adipose Tissue Is Associated With Coronary Heart Disease in Sudden Death Victims.
Mari-Alexandre J; (...); Zorio E
Article. 10.1016/j.rec.2017.12.007. 2019
Titin Missense Variants as a Cause of Familial Dilated Cardiomyopathy.
Dominguez, Fernando; (...); Garcia-Pavia, Pablo
Letter. 10.1161/CIRCULATIONAHA.122.062833. 2023
Truncating FLNC Mutations Are Associated With High-Risk Dilated and Arrhythmogenic Cardiomyopathies
Ortiz-Genga, MF; (...); Monserrat, L
Article. 10.1016/j.jacc.2016.09.927. 2016
Validation of multiparametric approaches for the prediction of sudden cardiac death in patients with Brugada syndrome and electrophysiological study.
Rodríguez-Mañero M; (...); Arbelo E
Article. 10.1016/j.rec.2021.07.007. 2021
Value of the "Standing Test" in the Diagnosis and Evaluation of Beta-blocker Therapy Response in Long QT Syndrome.
Muñoz-Esparza C; (...); Gimeno Blanes JR
Article. 10.1016/j.rec.2017.01.006. 2017