ESTUDIO MULTICENTRICO,DOBLE CIEGO, RANDOMIZADO, CONTROLADO CON PLACEBO, DE GRUPOS PARALELOS COMPARANDO LA EFICACIA Y SEGURIDAD POR VIA ORAL DE ELETRIPTAN (40 Y 80MG) Y ZOLMITRIPTAN (2,5 MG) ADMINISTRADOS PARA EL TRATAMIENTO AGUDO DE LA MIGRAÑA.

Dades bàsiques

Protocol:
A1601002
EURDRACT:
NO PROCEDE
NCT:
Centre:
Any inici:
Any de finalització:
ENSAYO CLÍNICO

Documents

  • No hi ha documents

Participants

Grups d'Investigació

Finançadors - Promotors

PFIZER, S.A.

Resultats de l'Assaig Clínic


A description of variant transthyretin amyloidosis (ATTRv) stage 1 patients and asymptomatic carriers in Spain: the EMPATIa study

Davila, Lucia Galan; (...); Tarilonte, Patricia

Article. 10.1186/s13023-024-03304-9. 2024

  • Open Access.

A novel TRMT5 mutation causes a complex inherited neuropathy syndrome: the role of nerve pathology in defining a demyelinating neuropathy.

Argente-Escrig, Herminia; (...); Sevilla, Teresa

Article. 10.1111/nan.12817. 2022

  • Open Access.

Analysis of Juvenile Onset Pompe Disease patients included in the Spanish Pompe Registry

Martinez Marin, R.; (...); Diaz Manera, J.

Meeting Abstract. 2022


Analysis of muscle magnetic resonance imaging of a large cohort of patient with VCP-mediated disease reveals characteristic features useful for diagnosis.

Esteller D; (...); Díaz-Manera J

Article. 10.1007/s00415-023-11862-4. 2023

  • Open Access.

AntimiR treatment corrects myotonic dystrophy primary cell defects across several CTG repeat expansions with a dual mechanism of action

Cerro-Herreros, Estefania; (...); Artero, Ruben

Article. 10.1126/sciadv.adn6525. 2024

  • Open Access.

Asymptomatic HyperCKemia in the Pediatric Population A Prospective Study Utilizing Next-Generation Sequencing and Ancillary Tests

Marti, Pilar; (...); Vilchez, Juan Jesus

Article. 10.1212/WNL.0000000000210116. 2025


Automatic etiological classification of stroke thrombus digital photographs using a deep learning model

Lucero-Garofano, Alvaro; (...); Manjon, Jose V.

Article. 10.3389/fneur.2025.1534845. 2025

  • Open Access.

Clinical and genetic characteristics of 21 Spanish patients with biallelic pathogenic SPG7 mutations.

Baviera-Muñoz R; (...); Espinós C

Article. 10.1016/j.jns.2021.118062. 2021


Clinical and genetic spectrum of a large cohort of delta-sarcoglycan muscular dystrophy

Alonso-Perez, J; (...); Diaz-Manera, J

Meeting Abstract. 10.1016/j.nmd.2021.07.202. 2021

  • Open Access.

Clinical features, mutation spectrum and factors related to reaching molecular diagnosis in a cohort of patients with distal myopathies.

Muelas, Nuria; (...); Vilchez, Juan J

Article. 10.1007/s00415-024-12821-3. 2025


Clot Composition Analysis as a Diagnostic Tool to Gain Insight into Ischemic Stroke Etiology: A Systematic Review

Aliena-Valero, Alicia; (...); Salom, Juan B.

Article. 10.5853/jos.2021.02306. 2021

  • Open Access.

Correction to: Analysis of muscle magnetic resonance imaging of a large cohort of patient with VCP-mediated disease reveals characteristic features useful for diagnosis.

Esteller D; (...); Díaz-Manera J

Correction. 10.1007/s00415-023-12178-z. 2024

  • Open Access.

CRISPR-Cas9 editing of a TNPO3 mutation in a muscle cell model of limb-girdle muscular dystrophy type D2.

Poyatos-Garcia, Javier; (...); Vilchez, Juan Jesus

Article. 10.1016/j.omtn.2023.01.004. 2023

  • Open Access.

Characterizing SOD1 mutations in Spain. The impact of genotype, age, and sex in the natural history of the disease.

Vazquez-Costa, Juan F.; (...); Garcia-Redondo, Alberto

Article. 10.1111/ene.15661. 2022

  • Open Access.

Charcot-Marie-Tooth disease due to MORC2 mutations in Spain

Sivera R; (...); Sevilla T

Article. 10.1111/ene.15001. 2021

  • Open Access.

Deletion of exons 45 to 55 in the DMD gene: from the therapeutic perspective to the in vitro model

Poyatos-Garcia, Javier; (...); Vilchez, Juan J

Article. 10.1186/s13395-024-00353-3. 2024

  • Open Access.

DEPRESSION IN PATIENTS WITH CHARCOT-MARIE-TOOTH DISEASE TYPE 1A (CMT1A): FINDINGS FROM A REAL-WORLD DIGITAL STUDY

Thomas, Florian; (...); Boutalbi, Youcef

Meeting Abstract. 2022


Diagnostic Efficacy of Genetic Studies in a Series of Hereditary Cerebellar Ataxias in Eastern Spain.

Baviera-Munoz, Raquel; (...); Aller, Elena

Article. 10.1212/NXG.0000000000200038. 2022

  • Open Access.

Digenic inheritance involving a muscle-specific protein kinase and the giant titin protein causes a skeletal muscle myopathy.

Topf, Ana; (...); Straub, Volker

Article. 10.1038/s41588-023-01651-0. 2024

  • Open Access.

Disseminated toxoplasma infection after hematopoietic stem cell transplantation with myositis and encephalitis.

Asensi Cantó P; (...); Guerreiro M

Article. 10.1111/tid.14067. 2023

  • Open Access.

DRP2 mutations as a cause of Charcot Marie Tooth in Spain

Sivera, R.; (...); Sevilla, T.

Meeting Abstract. 2023


Drug-refractory myasthenia gravis: Clinical characteristics, treatments, and outcome.

Cortes-Vicente, Elena; (...); Gallardo, Eduard

Article. 10.1002/acn3.51492. 2022

  • Open Access.

Dystrophinopathy Phenotypes and Modifying Factors in DMD Exon 45-55 Deletion

Poyatos-Garcia, Javier; (...); Jesus Vilchez, Juan

Article. 10.1002/ana.26461. 2022

  • Open Access.

Effects of Spinal Cord Stimulation in Patients with Small Fiber and Associated Comorbidities from Neuropathy After Multiple Etiologies

Canos-Verdecho, Angeles; (...); Morales-Suarez-Varela, Maria

Article. 10.3390/jcm14020652. 2025

  • Open Access.

Expanding the Clinical Spectrum of DRP2-Associated Charcot-Marie-Tooth Disease.

Sivera R; (...); Sevilla T

Article. 10.1212/WNL.0000000000209174. 2024


Expanding the phenotype of GARS1 mutations

Sivera, R.; (...); Teresa, S.

Meeting Abstract. 2023


Genotype and phenotype spectrum of SORD neuropathy

Cortese, A; (...); SORD Nat Hist Study Grp

Meeting Abstract. 2021


Givinostat in DMD: results of the Epidys Study

Mercuri, E.; (...); McDonald, C.

Meeting Abstract. 10.1016/j.nmd.2022.07.223. 2022

  • Open Access.

Hereditary transthyretin amyloidosis caused by the Val142Ile variant in Spain.

de Frutos, Fernando; (...); Gonzalez-Costello, Jose

Article. 10.1016/j.rec.2024.12.012. 2025


Hereditary transthyretin amyloidosis caused by Val142Ile variant in Spain: phenotypic characteristics, geographic distribution and population frequency

Seminario, F. De Frutos; (...); Gonzalez-Costello, J.

Meeting Abstract. 10.1093/eurheartj/ehae666.2073. 2024

  • Open Access.

HIGH CELL-FREE HEMOGLOBIN AND IRON LEVELS IN CLOTS OF COVID-19 STROKE PATIENTS: A NOVEL MECHANISM LINKED TO SARS-COV-2 INDUCED PROTHROMBOTIC STATE

Paya, M.; (...); Segura, T.

Meeting Abstract. 2024


Human skeletal myopathy myosin mutations disrupt myosin head sequestration

Carrington, Glenn; (...); Ochala, Julien

Article. 2023


Human skeletal myopathy myosin mutations disrupt myosin head sequestration.

Carrington, Glenn; (...); Ochala, Julien

Article. 10.1172/jci.insight.172322. 2023

  • Open Access.

Impact of SARS-CoV-2 infection and COVID-19 pandemic on the morbidity and mortality of amyotrophic lateral sclerosis patients in Valencia, Spain

Garcia-Casanova, Pilar H.; (...); Vazquez-Costa, Juan F.

Article. 10.1111/ene.16465. 2024

  • Open Access.

Insights into phenotypic variability caused by GARS1 pathogenic variants.

Jiménez-Jiménez J; (...); Sivera R

Article. 10.1111/ene.16416. 2024

  • Open Access.

ITPR3-associated neuropathy: Report of a further family with adult onset intermediate Charcot-Marie-Tooth disease.

Cabello-Murgui, Javier; (...); Sivera, Rafael

Article. 10.1111/ene.16485. 2024

  • Open Access.

KY mutations are a cause of distal neuromyopathies

Muelas, N.; (...); Vilchez, J.

Meeting Abstract. 2023


Management of Hereditary Transthyretin Amyloidosis (ATTRv) Patients and Asymptomatic Carriers in Spain: The EMPATIa Study.

Losada Lopez, Ines; (...); Setaro, Francesca

Article. 10.3390/jcm13247587. 2024

  • Open Access.

Mitochondrial developmental encephalopathy with bilateral optic neuropathy related to homozygous variants in IMMT gene.

Marco-Hernández AV; (...); Martínez-Castellano F

Article. 10.1111/cge.14093. 2022


Msi2 enhances muscle dysfunction in a myotonic dystrophy type 1 mouse model.

Sabater-Arcis, Maria; (...); Artero, Ruben

Article. 10.1016/j.bj.2023.100667. 2023

  • Open Access.

Muscle MRI-phenotyping of patients with likely pathogenic anoctamin 5 variants

Poulsen, N.; (...); Vissing, J.

Meeting Abstract. 10.1016/j.nmd.2024.07.187. 2024

  • Open Access.

Myosin ATPase inhibition fails to rescue the metabolically dysregulated proteome of nebulin-deficient muscle.

Laitila, Jenni; (...); Ochala, Julien

Article. 10.1113/JP286870. 2024

  • Open Access.

Myosin dysregulation in nemaline myopathy

Laitila, J.; (...); Ochala, J.

Article. 10.1016/j.nmd.2022.07.017. 2022

  • Open Access.

NATURAL HISTORY STUDY OF SORD NEUROPATHY

Cortese, Andrea; (...); Zuchner, Stephan

Meeting Abstract. 2022


NEB mutations disrupt the super-relaxed state of myosin and remodel the muscle metabolic proteome in nemaline myopathy.

Ranu, Natasha; (...); Ochala, Julien

Article. 10.1186/s40478-022-01491-9. 2023

  • Open Access.

New developments and data highlights in the international myotubular and centronuclear myopathy patient registry

Laitila, J.; (...); Ochala, J.

Meeting Abstract. 10.1016/j.nmd.2022.07.018. 2022

  • Open Access.

Nusinersen in adult patients with 5q spinal muscular atrophy: Amulticenter observational cohorts' study.

Vazquez-Costa, Juan F.; (...); Hervas, David

Article. 10.1111/ene.15501. 2022

  • Open Access.

Onasemnogene Abeparvovec Administration via Peripherally Inserted Central Catheter: A Case Report.

Pitarch Castellano, Inmaculada; (...); Poveda Andres, Jose L

Case Reports. 10.3390/children11050590. 2024

  • Open Access.

PATIENT-REPORTED SYMPTOM BURDEN OF CHARCOT-MARIE-TOOTH DISEASE TYPE 1A (CMT1A): FINDINGS FROM A REAL-WORLD DIGITAL STUDY

Thomas, Florian; (...); Boutalbi, Youcef

Meeting Abstract. 2022


Patient-Reported Symptom Burden of Charcot-Marie-Tooth Disease Type 1A: Findings From an Observational Digital Lifestyle Study.

Thomas, Florian P; (...); Boutalbi, Youcef

Article. 10.1097/CND.0000000000000426. 2022

  • Open Access.

Pediatric inherited peripheral neuropathy: a prospective study at a Spanish referral center

Argente-Escrig H; (...); Sevilla T

Article. 10.1002/acn3.51432. 2021

  • Open Access.

Phenotype and clinical outcomes of Glu89Lys hereditary transthyretin amyloidosis: a new endemic variant in Spain.

de Frutos, Fernando; (...); Garcia-Pavia, Pablo

Article. 10.1080/13506129.2022.2142110. 2022

  • Open Access.

Preclinical characterization of antagomiR-218 as a potential treatment for myotonic dystrophy.

Cerro-Herreros, E; (...); Artero, R

Article. 10.1016/j.omtn.2021.07.017. 2021

  • Open Access.

Presenilin-1 Mutations Are a Cause of Primary Lateral Sclerosis-Like Syndrome

Vazquez-Costa, JF; (...); SEVILLA, T

Article. 10.3389/fnmol.2021.721047. 2021

  • Open Access.

Proprotein convertase subtilisin/kexin type 9 inhibitors in secondary prevention of vascular events in patients with stroke: Consensus document and practice guidance.

Gil-Núñez A; (...); Palacio E

Practice Guideline. 10.1016/j.nrleng.2020.11.014. 2022

  • Open Access.

Quantitative magnetic resonance imaging assessment of muscle composition in myotonic dystrophy mice

Bargiela, Ariadna; (...); Artero, Ruben

Article. 10.1038/s41598-023-27661-w. 2023

  • Open Access.

Randomized phase 2 study of ACE-083, a muscle-promoting agent, in facioscapulohumeral muscular dystrophy.

Statland, Jeffrey M.; (...); Attie, Kenneth M.

Article. 10.1002/mus.27558. 2022

  • Open Access.

Real life experience of tafamidis for the treatment of Spanish patients with Val30Met transthyretin amyloidosis with polyneuropathy.

Sanso, Maria Antonia Ribot; (...); Gonzalez-Moreno, Juan

Article. 10.1016/j.medcli.2024.01.008. 2024


Reperfusion therapy in acute ischaemic stroke due to cervical and cerebral artery dissection: Results from a Spanish multicentre study.

Campo-Caballero D; (...); Serena J

Article. 10.1016/j.nrleng.2020.10.012. 2023


Risdiplam in non-sitter patients aged 16years and older with 5q spinal muscular atrophy.

Nungo Garzon, Nancy Carolina; (...); Vazquez-Costa, Juan F

Article. 10.1002/mus.27804. 2023

  • Open Access.

Role of the nigrosome 1 absence as a biomarker in amyotrophic lateral sclerosis

Isabel Moreno-Gambin, Maria; (...); Vázquez-Costa JF

Article. 10.1007/s00415-021-10729-w. 2021

  • Open Access.

Safety and Efficacy of ApTOLL in Patients With Ischemic Stroke Undergoing Endovascular Treatment: A Phase 1/2 Randomized Clinical Trial.

Hernandez-Jimenez, Macarena; (...); Ribo, Marc

Article. 10.1001/jamaneurol.2023.1660. 2023

  • Open Access.

Safety and efficacy of givinostat in boys with Duchenne muscular dystrophy (EPIDYS): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial.

Mercuri E; (...); McDonald CM

Article. 10.1016/S1474-4422(24)00036-X. 2024


Safety and efficacy of losmapimod in facioscapulohumeral muscular dystrophy (ReDUX4): a randomised, double-blind, placebo-controlled phase 2b trial.

Tawil R; (...); Jiang JG

Article. 10.1016/S1474-4422(24)00073-5. 2024


Safety and efficacy of nipocalimab in adults with generalised myasthenia gravis (Vivacity-MG3): a phase 3, randomised double-blind, placebo-controlled study

Antozzi, Carlo; (...); Sun, Hong

Article. 2025


Safety and Efficacy of Nipocalimab in Patients With Generalized Myasthenia Gravis: Results From the Randomized Phase 2 Vivacity-MG Study

Antozzi, Carlo; (...); Arroyo, Santiago

Article. 10.1212/WNL.0000000000207937. 2024

  • Open Access.

SERUM AUTOANTIBODY LOWERING BY THE ANTI-FCRN MONOCLONAL ANTIBODY, NIPOCALIMAB, CORRELATES WITH CLINICAL IMPROVEMENT IN GENERALIZED MYASTHENIA GRAVIS PATIENTS

Guptill, Jeffrey; (...); Sun, Hong

Meeting Abstract. 2022


Spanish Pompe Registry: New data based on the 130 patients included

Marin, R. Martinez; (...); Manera, J. Diaz

Meeting Abstract. 2023


The cross-sectional area of the median nerve: An independent prognostic biomarker in amyotrophic lateral sclerosis.

Martinez-Paya, J J; (...); Vazquez-Costa, J F

Article. 10.1016/j.nrleng.2024.07.003. 2024

  • Open Access.

Therapeutic potential of oleic acid supplementation in myotonic dystrophy muscle cell models.

Moreno, Nerea; (...); Artero, Ruben

Article. 10.1186/s40659-024-00496-z. 2024

  • Open Access.

Use of NGS for diagnosis of asymptomatic hyperCKemia in childhood

Marti, P; (...); VILCHEZ, J

Meeting Abstract. 10.1016/j.nmd.2021.07.340. 2021

  • Open Access.

Validación de la versión española de la Charcot-Marie-Tooth Disease Pediatric Scale (CMTPedS).

Pitarch-Castellano I; (...); Burns J

Article. 10.33588/rn.7403.2021489. 2022


Validation of Neuromyotype: A smart keyboard for the evaluation of spinal muscular atrophy patients.

Cortes, P Lizandra; (...); Vázquez-Costa JF

Article. 10.1016/j.nrleng.2022.05.001. 2022

  • Open Access.

Vamorolone versus placebo and prednisone in Duchenne muscular dystrophy: results from a 24-week double-blind randomized trial

Guglieri, M; (...); Andres Sant Joan Deu Hosp

Meeting Abstract. 2021


VIVACITY-MG: A PHASE 2, MULTICENTER, RANDOMIZED, DOUBLE- BLIND, PLACEBO-CONTROLLED STUDY TO EVALUATE THE SAFETY, TOLERABILITY, EFFICACY, PHARMACO-KINETICS, PHARMACODYNAMICS, AND IMMUNOGENICITY OF NIPOCALIMAB ADMINISTERED TO ADULTS WITH GENERALIZED MYASTHENIA GRAVIS

Antozzi, Carlo; (...); Arroyo, Santiago

Meeting Abstract. 2023


Vivacity-MG: A Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, Efficacy, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of Nipocalimab Administered to Adults with Generalized Myasthenia Gravis

Guptill, Jeffrey; (...); Arroyo, Santiago

Meeting Abstract. 2021


WORK IMPACTS IN PATIENTS WITH CHARCOT-MARIE-TOOTH DISEASE TYPE 1A (CMT1A): FINDINGS FROM A REAL-WORLD DIGITAL STUDY

Thomas, Florian; (...); Boutalbi, Youcef

Meeting Abstract. 2022


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