TRANSPORTE NÚCLEO CITOPLASMA Y CAMBIOS DE EXPRESIÓN GÉNICA EN LA INSUFICIENCIA CARDIACA. PUESTA EN MARCHA DE UNA NUEVA ESTRATEGIA TERAPÉUTICA.

Datos básicos

Protocolo:
PI13/00100
EUDRACT:
NO PROCEDE
NCT:
Centro:
Año de incio:
2014
Año de finalización:
2017
PI BIOMÉDICA 138.545,00 €

Objetivos del proyecto

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Documentos

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Participantes

Grupos

Financiadores - Promotores

FUNDACIÓN PARA LA INVESTIGACIÓN DEL HOSPITAL UNIVERSITARIO LA FE DE LA COMUNIDAD VALENCIANA
INSTITUTO DE SALUD CARLOS III

Resultados del Ensayo Clínico


20 years of leptin: Role of leptin in cardiomyocyte physiology and physiopathology

Feijóo-Bandín S; (...); Lago F

Review. 10.1016/j.lfs.2015.02.016. 2015


24 h nesfatin-1 treatment promotes apoptosis in cardiomyocytes

Feijóo-Bandín S; (...); Lago F

Editorial Material. 10.1007/s12020-015-0648-0. 2016


7,8-hydroxy-2 '-deoxyguanosine/2 '-deoxiguanosine ratio determined in hydrolysates of brain DNA by ultrachromatrography coupled to tandem mass spectrometry

Torres-Cuevas, I; (...); Escobar, J

Article. 10.1016/j.talanta.2017.03.072. 2017


A clinical perspective on the utility of alpha 1 antichymotrypsin for the early diagnosis of calcific aortic stenosis

Martin-Rojas T; (...); Barderas MG

Article. 10.1186/s12014-017-9147-z. 2017

  • Open Access.

Adipokines and Inflammation: Focus on Cardiovascular Diseases.

Feijóo-Bandín S; (...); Lago F

Review. 10.3390/ijms21207711. 2020

  • Open Access.

Alpha-cardiac Actin Serum Expression Levels Detect Acute Cellular Rejection in Heart Transplant Patients.

Perez-Carrillo, Lorena; (...); Rosello-Lleti, Esther

Article. 10.1097/TP.0000000000004273. 2022

  • Open Access.

Alteration in Golgi apparatus fragmentation related genes in human dilated cardiomyopathy.

Gonzalez-Torrent, Irene; (...); Rosello-Lleti, Esther

Article. 10.1038/s41598-025-92758-3. 2025

  • Open Access.

Alterations in Mitochondrial Oxidative Phosphorylation System: Relationship of Complex V and Cardiac Dysfunction in Human Heart Failure

Gimenez-Escamilla, Isaac; (...); Rosello-Lleti, Esther

Article. 10.3390/antiox13030285. 2024

  • Open Access.

Alterations in the Nucleocytoplasmic Transport in Heart Transplant Rejection.

Lozano-Edo, Silvia; (...); Martinez-Dolz, Luis

Article. 10.1016/j.transproceed.2021.09.003. 2021


Alterations of mitochondrial bioenergetics in human hearts with ischemic and dilated cardiomyopathy

Tarazon, E.; (...); Rosello-Lleti, E.

Meeting Abstract. 2023


Altered expression of thyroid hormone biosynthesis machinery in the ischemic heart. Potential role of epigenomics

Rosello-Lleti, EE; (...); Portoles, M

Meeting Abstract. 2017


Altered MicroRNA Maturation in Ischemic Hearts: Implication of Hypoxia on XPO5 and DICER1 Dysregulation and RedoximiR State.

Perez-Carrillo, Lorena; (...); Rosello-Lleti, Esther

Article. 10.3390/antiox12071337. 2023

  • Open Access.

Altered miRNA maturation in ischemic cardiomyopathy: implication of miRNA biogenesis and redox-sensitive miRNA regulation

Estefania Tarazon, E. T.; (...); Rosello-Lleti, E.

Meeting Abstract. 2023


Analysis of the snoRNA profile in ischemic and dilated cardiomyopathy

Tarazon, E.; (...); Rosello-Lleti, E.

Meeting Abstract. 2023


Anthracycline mediated cardiotoxicity: Detection of miRNA based early biomarkers for the prediction of myocardial injury. Hecatos study

Coloma, C. Salvador; (...); Santaballa, A.

Meeting Abstract. 10.1093/annonc/mdw365.69. 2016


ASB1 differential methylation closely relates to left ventricular function and stroke volume in ischaemic cardiomyopathy patients

Rosello-Lleti, EE; (...); Rivera, M

Meeting Abstract. 2017


ASB1 differential methylation in ischaemic cardiomyopathy: relationship with left ventricular performance in end-stage heart failure patients

Ortega, A; (...); Rivera, M

Article. 10.1002/ehf2.12289. 2018

  • Open Access.

ATP synthase subunit alpha and LV mass in ischaemic human hearts

Roselló-Lletí E; (...); Rivera M

Article. 10.1111/jcmm.12477. 2015


BH4 Increases nNOS Activity and Preserves Left Ventricular Function in Diabetes.

Carnicer, Ricardo; (...); Casadei, Barbara

Article. 10.1161/CIRCRESAHA.120.316656. 2021

  • Open Access.

Cardiac Allograft Rejection Induces Changes in Nucleocytoplasmic Transport: RANGAP1 as a Potential Non-Invasive Biomarker.

Lozano-Edo, Silvia; (...); Martinez-Dolz, Luis

Article. 10.3390/jpm12060913. 2022

  • Open Access.

Cardiac rejection diagnosis using serum mRNA encoding proteins related to fibrotic process

Rosello-Lleti, E.; (...); Tarazon, E.

Meeting Abstract. 2023


Cardiac S1P/Ceramide imbalance in human heart failure: implication of gene dysregulation

Perez Carrillo, L.; (...); Tarazon, E.

Meeting Abstract. 2021


Cardiac sodium/hydrogen exchanger (NHE11) as a novel potential target for SGLT2i in heart failure

Perez-Carrillo, L.; (...); Rosello-Lleti, E.

Meeting Abstract. 2022


CCSER2 and RAC3 serum expression levels detect cardiac allograft rejection

Rodriguez, J. M.; (...); Rosello-Lleti, E.

Meeting Abstract. 2021


Circulating long non-coding RNAs detection after heart transplantation and its accuracy in the diagnosis of acute cardiac rejection.

Pérez-Carrillo L; (...); Roselló-Lletí E

Letter. 10.1186/s40364-024-00590-0. 2024

  • Open Access.

Circulating mitochondrial genes detect acute cardiac allograft rejection: Role of the mitochondrial calcium uniporter complex.

Tarazón E; (...); Roselló-Lletí E

Article. 10.1111/ajt.16387. 2020

  • Open Access.

Circulating sphingosine-1-phosphate as a non-invasive biomarker of heart transplant rejection

ROSELLO, E.; (...); PORTOLES, M.

Meeting Abstract. 2019


Circulating Sphingosine-1-Phosphate as A Non-Invasive Biomarker of Heart Transplant Rejection.

TARAZON, E.; (...); ROSELLO, E.

Article. 10.1038/s41598-019-50413-8. 2019

  • Open Access.

Clinical characteristics and outcomes of elderly included in the Spanish Drug-Induced Liver Injury (DILI) Registry

Slim, M; (...); Andrade, RJ

Meeting Abstract. 10.1016/S0168-8278(17)31154-6. 2017


Combining Serum miR-144-3p and miR-652-3p as Potential Biomarkers for the Early Diagnosis and Stratification of Acute Cellular Rejection in Heart Transplantation Patients.

Pérez-Carrillo L; (...); Roselló-Lletí E

Article. 10.1097/TP.0000000000004622. 2023

  • Open Access.

Combining serum miR-144-3p and miR-652-3p as potential biomarkers for the early diagnosis and stratification of acute cellular rejection in heart transplantation patients

Perez-Carrillo, L.; (...); Rosello-Lleti, E.

Meeting Abstract. 2022


Correlation of various molecules involved in cellular traffic with the severity of heart failure in patients undergoing cardiac transplantation

Ezzitouny, M.; (...); Martinez-Dolz, L.

Meeting Abstract. 2018


Changes in human Golgi apparatus reflect new left ventricular dimensions and function in dilated cardiomyopathy patients

Tarazon, E; (...); Rivera, M

Letter. 10.1002/ejhf.671. 2017


Diagnostic power of echocardiographic speckle tracking of the tricuspid annular motion to assess right ventricular dysfunction

Alonso P; (...); Salvador A

Letter. 10.1016/j.ijcard.2013.12.157. 2014


Diagnostic value of serum miR-144-3p for the detection of acute cellular rejection in heart transplant patients.

Perez-Carrillo, Lorena; (...); Rosello-Lleti, Esther

Article. 10.1016/j.healun.2021.10.004. 2022

  • Open Access.

Differential gene expression of C-type natriuretic peptide and its related molecules in dilated and ischemic cardiomyopathy. A new option for the management of heart failure

Tarazón E; (...); Portolés M

Letter. 10.1016/j.ijcard.2014.04.037. 2014


Disturbance of iron metabolism related genes in advanced heart failure

Tarazon, E.; (...); Rosello-Lleti, E.

Meeting Abstract. 2023


DNA methylation changes in ischemic cardiomyopathy

Perez Carrillo, L.; (...); Esther Rosello-Lleti, E.

Meeting Abstract. 2020


DNMT3B System Dysregulation Contributes to the Hypomethylated State in Ischaemic Human Hearts

Tarazon, Estefania; (...); Rosello-Lleti, Esther

Article. 10.3390/biomedicines10040866. 2022

  • Open Access.

Does the calcineurin inhibitor have influence on cytomegalovirus infection in heart transplantation?

Rodríguez-Serrano M; (...); Salvador-Sanz A

Article. 10.1111/ctr.12282. 2014


Does the Calcineurin Inhibitor Have Influence on Cytomegalovirus Infection in Heart Transplantation?

Sanchez-Lazaro, I.; (...); Salvador-Sanz, A.

Article. 10.1016/j.healun.2014.01.067. 2014


Economic evaluation in collaborative hospital drug evaluation reports.

Ortega A; (...); Dranitsaris G

Article. 10.7399/fh.2015.39.5.9361. 2015

  • Open Access.

Electron microscopy reveals evidence of perinuclear clustering of mitochondria in cardiac biopsy proven allograft rejection

Rosello-Lleti, E.; (...); Portoles, M.

Meeting Abstract. 2019


Electron Microscopy Reveals Evidence of Perinuclear Clustering of Mitochondria in Cardiac Biopsy-Proven Allograft Rejection.

Tarazon, Estefania; (...); Rosello-Lleti, Esther

Article. 10.3390/jpm12020296. 2022

  • Open Access.

Emerging role of circulating piRNAs in the diagnosis of heart transplant rejection.

Perez-Carrillo, Lorena; (...); Rosello-Lleti, Esther

Article. 10.1016/j.healun.2024.11.039. 2024

  • Open Access.

Empagliflozin reduces the levels of CD36 and cardiotoxic lipids while improving autophagy in the hearts of Zucker diabetic fatty rats.

Aragón-Herrera A; (...); Lago F

Article. 10.1016/j.bcp.2019.113677. 2019


Endolysosomal two-pore channels regulate autophagy in cardiomyocytes

Garcia-Rua, V; (...); Lago, F

Article. 10.1113/JP271332. 2016

  • Open Access.

Endoplasmic Reticulum Stress Induces Different Molecular Structural Alterations in Human Dilated and Ischemic Cardiomyopathy

Ortega A; (...); Portolés M

Article. 10.1371/journal.pone.0107635. 2014

  • Open Access.

Expression of golgi genes are related to the degree of ventricular remodeling in heart failure

Rosello-Lleti, EE; (...); Rivera, M

Meeting Abstract. 2017


Functional Networks of Nucleocytoplasmic Transport-Related Genes Differentiate Ischemic and Dilated Cardiomyopathies. A New Therapeutic Opportunity

Molina-Navarro MM; (...); Rivera M

Article. 10.1371/journal.pone.0104709. 2014

  • Open Access.

Functional recovery in AAV9-shXPO1-treated rats with chronic induced myocardial infarction. A preliminary study

Rosello-Lleti, EE; (...); Rivera, M

Meeting Abstract. 2017


Gene expression network analysis reveals new transcriptional regulators as novel factors in human ischemic cardiomyopathy

Herrer I; (...); Rivera M

Article. 10.1186/s12920-015-0088-y. 2015


Golgi Apparatus fragmentation in dilated cardiomyopathy and its relationship with the alteration of vesicular transport

Gimenez-Escamilla, I.; (...); Rosello-Lleti, E.

Meeting Abstract. 2022


Golgi ribbon integrity in human patients with chronic heart failure

Gimenez Escamilla, I.; (...); Tarazon, E.

Meeting Abstract. 2021


Heart Mitochondrial Proteome Study Elucidates Changes in Cardiac Energy Metabolism and Antioxidant PRDX3 in Human Dilated Cardiomyopathy

Roselló-Lletí E; (...); Rivera M

Article. 10.1371/journal.pone.0112971. 2014

  • Open Access.

Human Ischemic Cardiomyopathy Shows Cardiac Nos1 Translocation and its Increased Levels are Related to Left Ventricular Performance

Rosello-Lleti E; (...); Rivera M

Article. 10.1038/srep24060. 2016

  • Open Access.

Human recombinant relaxin-2 (serelaxin) regulates the proteome, lipidome, lipid metabolism and inflammatory profile of rat visceral adipose tissue.

Aragon-Herrera, Alana; (...); Lago, Francisca

Article. 10.1016/j.bcp.2024.116157. 2024

  • Open Access.

Identification of sarcomere serum biomarkers for non-invasive diagnosis of cardiac rejection

Perez Carrillo, L.; (...); Esther Rosello-Lleti, E.

Meeting Abstract. 2021


Impact of circulatory assistance in the early evolution after heart transplantation: unicentric experience.

Martinez-Lauwers, A.; (...); Martinez-Dolz, L.

Meeting Abstract. 2020


Implication of Sphingolipid Metabolism Gene Dysregulation and Cardiac Sphingosine-1-Phosphate Accumulation in Heart Failure.

Perez-Carrillo, Lorena; (...); Tarazon, Estefania

Article. 10.3390/biomedicines10010135. 2022

  • Open Access.

Implication of sphingolipid metabolism gene dysregulation and cardiac sphingosine-1-phosphate accumulation in heart failure

Perez Carrillo, L.; (...); Tarazon, E.

Meeting Abstract. 2021


Incidence of Development of Obesity After Heart Transplantation According to the Calcineurin Inhibitor

López-Vilella R; (...); Montero-Argudo A

Article. 10.1016/j.transproceed.2014.11.025. 2015


Incidence of Development of Obesity After Heart Transplantation According to the Calcineurin Inhibitor (vol 47, pg 127, 2015)

Lopez-Vilella, R.; (...); Montero-Argudo, A.

Article. 10.1016/j.transproceed.2015.09.023. 2015


Indirect effects of cytomegalovirus infection and the utility of utility of valganciclovir

Martinez-Dolz, L.; (...); Almenar-Bonet, L.

Article. 2014


Initial Experience with a New Image Integration Module Designed for Reducing Radiation Exposure During Electrophysiological Ablation Procedures

Cano Ó; (...); Martínez-Dolz L

Article. 10.1111/jce.12659. 2015


Intercalated disc in failing hearts from patients with dilated cardiomyopathy: Its role in the depressed left ventricular function

Ortega, A; (...); Rivera, M

Article. 10.1371/journal.pone.0185062. 2017

  • Open Access.

Intercalated discs in human dilated cardiomyopathy: molecular and ultrastructural remodeling and its relationship to left ventricular function

Rosello-Lleti, EE; (...); Rivera, M

Meeting Abstract. 2017


Intravenous sildenafil in right ventricular dysfunction with pulmonary hypertension following a heart transplant.

Bonet LA; (...); Sanz AS

Article. 10.5301/HEART.2014.12492. 2014


iTRAQ proteomic analysis of extracellular matrix remodeling in aortic valve disease

Martin-Rojas T; (...); Barderas MG

Article. 10.1038/srep17290. 2015

  • Open Access.

Metabolic alterations derived from absence of Two-Pore Channel 1 at cardiac level

Garcia-Rua, V; (...); Lago, F

Article. 10.1007/s12038-016-9647-4. 2016


METABOLIC PROFILING OF HEARTS FROM RATS TREATED WITH SERELAXIN

Aragon-Herrera, A; (...); Aragon-Herrera, A

Meeting Abstract. 2018


Metabolic profiling reveals significant alterations in glycerophospholipid and sphingolipid content in hearts from rats treated with relaxin

Aragon-Herrera, A; (...); Lago, F

Meeting Abstract. 2018


Meteorin-like plasma levels as a novel biomarker for heart failure

Anido Varela, L.; (...); Gonzalez-Juanatey, J. R.

Meeting Abstract. 2023


Meteorin-like plasma levels as a novel biomarker for heart failure

Feijoo-Bandin, S.; (...); Gonzalez-Juanatey, J. R.

Meeting Abstract. 2024


Meteorin-like protein plasma levels are associated with worse outcomes in de novo heart failure.

Anido-Varela, Laura; (...); Lago, Francisca

Article. 10.1111/eci.14380. 2025


MiR-138-5p Suppresses Cell Growth and Migration in Melanoma by Targeting Telomerase Reverse Transcriptase.

Tarazon, Estefania; (...); Botella Estrada, Rafael

Article. 10.3390/genes12121931. 2021

  • Open Access.

Mitochondrial dynamic processes in left ventricular tissue from heart failure patients

Garcia Bolufer, P.; (...); Esther Rosello-Lleti, E.

Meeting Abstract. 2020


Molecular Alterations of Nucleocytoplasmic Transport in Patients on the Heart Transplantation Waiting List and Its Correlation With the Severity and Etiology of Heart Failure.

Ezzitouny, M.; (...); Martinez-Dolz, L.

Article. 10.1016/j.transproceed.2018.12.013. 2019


Myocardium of patients with dilated cardiomyopathy presents altered expression of genes involved in thyroid hormone biosynthesis

Gil-Cayuela, C; (...); Portoles, M

Article. 10.1371/journal.pone.0190987. 2018

  • Open Access.

New Altered Non-Fibrillar Collagens in Human Dilated Cardiomyopathy: Role in the Remodeling Process

Gil-Cayuela, C; (...); Rivera, M

Article. 10.1371/journal.pone.0168130. 2016

  • Open Access.

New Cell Adhesion Molecules in Human Ischemic Cardiomyopathy. PCDHGA3 Implications in Decreased Stroke Volume and Ventricular Dysfunction

Ortega, Ana; (...); Rosello-Lleti, Esther

Article. 10.1371/journal.pone.0160168. 2016

  • Open Access.

Non-invasive diagnosis of cardiac rejection using small non-coding RNAs

Gimenez-Escamilla, I.; (...); Rosello-Lleti, E.

Meeting Abstract. 2022


Patients with Dilated Cardiomyopathy and Sustained Monomorphic Ventricular Tachycardia Show Up-Regulation of KCNN3 and KCNJ2 Genes and CACNG8-Linked Left Ventricular Dysfunction

Ortega A; (...); Rivera M

Article. 10.1371/journal.pone.0145518. 2015

  • Open Access.

Plasma CD5L and non-invasive diagnosis of acute heart rejection.

Tarazón E; (...); Roselló-Lletí E

Article. 10.1016/j.healun.2019.11.004. 2020

  • Open Access.

Plasma fibroblast activation protein is decreased in acute heart failure despite cardiac tissue upregulation

Delgado-Arija, Marta; (...); Rosello-Lleti, Esther

Article. 10.1186/s12967-024-04900-w. 2024

  • Open Access.

Plasma Levels of SERCA2a as a Noninvasive Biomarker of Primary Graft Dysfunction After Heart Transplantation.

Lozano-Edo S; (...); Martínez-Dolz L

Article. 10.1097/TP.0000000000003798. 2021


Plasma levels of the proinflammatory adipocytokine chemerin correlate with lean/fat mass index in patients with heart failure

Herrera, AA; (...); Lago, F

Meeting Abstract. 2017


Prevalence of fragmented QRS complex and factors related with its occurrence

Martinez-Dolz, L.; (...); Almenar-Bonet, L.

Article. 2014


Prospective Multicenter Study of Carbapenemase-Producing Enterobacteriaceae from 83 Hospitals in Spain Reveals High In Vitro Susceptibility to Colistin and Meropenem

Oteo J; (...); GEIH-GEMARA (SEIMC) and REIPI

Article. 10.1128/AAC.00086-15. 2015


Protein Inhibitor of NOS1 Plays a Central Role in the Regulation of NOS1 Activity in Human Dilated Hearts

Rosello-Lleti E; (...); Rivera M

Article. 10.1038/srep30902. 2016

  • Open Access.

Protocol for Isolation of Golgi Vesicles from Human and Animal Hearts by Flotation through a Discontinuous Sucrose Gradient.

Tarazón E, Portolés M, Roselló-Lletí E

Article. 10.1016/j.xpro.2020.100100. 2020

  • Open Access.

Relationships of Telomere Homeostasis with Oxidative Stress and Cardiac Dysfunction in Human Ischaemic Hearts.

Tarazón E; (...); Roselló-Lletí E

Article. 10.3390/antiox10111750. 2021

  • Open Access.

Relaxin activates AMPK-AKT signaling and increases glucose uptake by cultured cardiomyocytes

Aragon-Herrera, A.; (...); Lago, F.

Article. 10.1007/s12020-018-1534-3. 2018


Relaxin has beneficial effects on liver lipidome and metabolic enzymes

Aragon-Herrera, A; (...); Lago, F

Article. 10.1096/fj.202002620RR. 2021


Relaxin-2 as a Potential Biomarker in Cardiovascular Diseases.

Aragon-Herrera, Alana; (...); Lago, Francisca

Article. 10.3390/jpm12071021. 2022

  • Open Access.

Relaxin-2 in Cardiometabolic Diseases: Mechanisms of Action and Future Perspectives

Feijoo-Bandin, S; (...); Lago, F

Article. 10.3389/fphys.2017.00599. 2017

  • Open Access.

RNA Sequencing Analysis and Atrial Natriuretic Peptide Production in Patients with Dilated and Ischemic Cardiomyopathy

Tarazón E; (...); Portolés M

Article. 10.1371/journal.pone.0090157. 2014

  • Open Access.

RNA Sequencing Analysis Identifies New Human Collagen Genes Involved in Cardiac Remodeling

Gil-Cayuela C; (...); Portolés M

Letter. 10.1016/j.jacc.2015.01.029. 2015


RNA-sequencing analysis reveals new alterations in cardiomyocyte cytoskeletal genes in patients with heart failure

Herrer I; (...); Portolés M

Article. 10.1038/labinvest.2014.54. 2014


Role of DNMT3B system in human ischemic hearts

Perez Carrillo, L.; (...); Rosello-Lleti, E.

Meeting Abstract. 2021


Role of Sodium-Glucose Co-Transporter 2 Inhibitors in the Regulation of Inflammatory Processes in Animal Models.

Feijoo-Bandin, Sandra; (...); Lago, Francisca

Article. 10.3390/ijms23105634. 2022

  • Open Access.

Sarcomere ACTC1 and MYO18A serum expression levels detect acute cellular rejection in cardiac transplant patients

Perez Carrillo, L.; (...); Rosello-Lleti, E.

Meeting Abstract. 2021


SERCA2a as non-invasive biomarker of heart transplant rejection

Rosello-Lleti, EE; (...); Rivera, M

Meeting Abstract. 2017


SERCA2a: A potential non-invasive biomarker of cardiac allograft rejection

Tarazon, E; (...); Rosello-Lleti, E

Article. 10.1016/j.healun.2017.07.003. 2017

  • Open Access.

Serelaxin (recombinant human relaxin-2) treatment affects the endogenous synthesis of long chain poly-unsaturated fatty acids and induces substantial alterations of lipidome and metabolome profiles in rat cardiac tissue

Aragon-Herrera, A; (...); Lago, F

Article. 10.1016/j.phrs.2019.04.009. 2019


Single Nucleotide Polymorphisms, SNPs, Associated With the Efficacy and Security of Immunosuppressive Treatment in Heart Transplantation

Sanchez-Lazaro, I.; (...); Salvador-Sanz, A.

Article. 10.1016/j.healun.2014.01.392. 2014


Study of molecules involved in cellular traffic in advanced heart failure: are there differences in the nivels of these molecules between ischemic heart disease and idiopathic dilated cardiomyopathy?

Ezzitouny, M.; (...); Martinez-Dolz, L.

Meeting Abstract. 2018


Systematic Implantation of Pacemaker/ICDs under Active Oral Anticoagulation Irrespective of Patient's Individual Preoperative Thromboembolic Risk

Cano Ó; (...); Martínez-Dolz L

Article. 10.1111/pace.12613. 2015


Telomeric machinery alterations in ischemic cardiomyopathy

Ramos Castellanos, P.; (...); Esther Rosello-Lleti, E.

Meeting Abstract. 2020


The Adipokine Chemerin Induces Apoptosis in Cardiomyocytes

Rodríguez-Penas D; (...); Lago F

Article. 10.1159/000430343. 2015


The altered expression of autophagy-related genes participates in heart failure: NRBP2 and CALCOCO2 are associated with left ventricular dysfunction parameters in human dilated cardiomyopathy

Gil-Cayuela, C; (...); Portoles, M

Article. 10.1371/journal.pone.0215818. 2019

  • Open Access.

The altered expression of autophagy-related genes participates in heart failure: NRBP2 and CALCOCO2 decrease left ventricular function in human dilated cardiomyopathy

Rosello-Lleti, E; (...); Portoles, M

Meeting Abstract. 2019


The central role of FAP dysregulation and cardiac fibroblast activation in heart failure patients

Rosello-Lleti, E.; (...); Tarazon, E.

Meeting Abstract. 2023


The lipidomic and inflammatory profiles of visceral and subcutaneous adipose tissues are distinctly regulated by the SGLT2 inhibitor empagliflozin in Zucker diabetic fatty rats.

Aragon-Herrera, Alana; (...); Lago, Francisca

Article. 10.1016/j.biopha.2023.114535. 2023

  • Open Access.

The Treatment With the SGLT2 Inhibitor Empagliflozin Modifies the Hepatic Metabolome of Male Zucker Diabetic Fatty Rats Towards a Protective Profile.

Aragon-Herrera, Alana; (...); Lago, Francisca

Article. 10.3389/fphar.2022.827033. 2022

  • Open Access.

The use of multisite left ventricular pacing via quadripolar lead improves acute haemodynamics and mechanical dyssynchrony assessed by radial strain speckle tracking: initial results

Osca J; (...); Salvador A

Article. 10.1093/europace/euv211. 2016


Thyroid hormone biosynthesis machinery is altered in the ischemic myocardium: An epigenomic study

Gil-Cayuela, C; (...); Portoles, M

Article. 10.1016/j.ijcard.2017.05.042. 2017


Transcriptomic Alterations in Spliceosome Components in Advanced Heart Failure: Status of Cardiac-Specific Alternative Splicing Factors

Gimenez-Escamilla, Isaac; (...); Rosello-Lleti, Esther

Article. 10.3390/ijms25179590. 2024


Transcriptomic analysis of the spliceosome in cardiac tissue of patients with heart failure

Gimenez Escamilla, I.; (...); Esther Rosello-Lleti, E.

Meeting Abstract. 2020


TRPM7 is down-regulated in both left atria and left ventricle of ischaemic cardiomyopathy patients and highly related to changes in ventricular function.

Ortega, A; (...); Rivera, M

Article. 10.1002/ehf2.12085. 2016

  • Open Access.

Two-pore channels (TPCs): Novel voltage-gated ion channels with pleiotropic functions

Feijoo-Bandin, S; (...); Lago, F

Review. 10.1080/19336950.2016.1213929. 2017

  • Open Access.

Use of a "CNI holidays" strategy in acute renal dysfunction late after heart transplant. Report of two cases.

Alonso P; (...); Montero A

Article. 2014


Utility of nucleocytoplasmic transport as a marker in critical heart failure with circulatory assistance as a bridge to transplant

Ezzitouny, M.; (...); Marinez-Dolz, L.

Meeting Abstract. 2020


Value of SERCA2a as a Biomarker for the Identification of Patients with Heart Failure Requiring Circulatory Support.

Ezzitouny M; (...); Martínez-Dolz L

Article. 10.3390/jpm11111122. 2021

  • Open Access.

Value of the Electrocardiogram as a Predictor of Right Ventricular Dysfunction in Patients With Chronic Right Ventricular Volume Overload.

Alonso P; (...); Salvador A

Article. 10.1016/j.rec.2014.04.019. 2015


XPO1 Gene Therapy Attenuates Cardiac Dysfunction in Rats with Chronic Induced Myocardial Infarction.

García-Manzanares M; (...); Rivera M

Article. 10.1007/s12265-019-09932-y. 2020

  • Open Access.

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