CARACTERIZACIÓN DE LOS INHIBIDORES EN PACIENTES CON DIAGNÓSTICO DE HEMOFILIA ADQUIRIDA

Datos básicos

Código:
SET-INM-2010-01
Protocolo:
SET-INM-2010-01
EUDRACT:
NCT:
Centro:
Dotación:
Año de incio:
Año de finalización:
2014
ESTUDIO OBSERVACIONAL

Documentos

  • No hay documentos

Participantes

Financiadores - Promotores

SOCIEDAD ESPAÑOLA DE TROMBOSIS Y HEMOSTASIA

Resultados del Ensayo Clínico


99.3% of Inhibitors in Severe Hemophilia a Develop before Exposure Day 75. Time to Change Definition of Previously Treated Patients; Data from 1038 Patients with Severe Hemophilia a of the Pednet Registry

Van den Berg, M; (...); Ljung, R

Meeting Abstract. 10.1182/blood-2018-99-114518. 2018


A MODIFICATION OF CALIBRATED AUTOMATED THROMBIN GENERATION ASSAY TO EXPLORE NEW COFACTORS OF ACTIVATED PROTEIN C IN PLASMA

Martos, L.; (...); Navarro Rosales, S.

Meeting Abstract. 10.1016/S0049-3848(14)50233-2. 2014


A NEW INTRONIC MUTATION CAUSES AN ABERRANT SPLICING IN THE ANK1 GENE

Liquori, A.; (...); Cervera, J., V

Meeting Abstract. 2018

  • Open Access.

A simplified assay for quantification of circulating activated protein C levels

Medina, P.; (...); Espana, F.

Article. 2013


A simplified assay for the quantification of circulating activated protein C

Martos L; (...); Medina P

Article. 10.1016/j.cca.2016.05.025. 2016


a2-Macroglobulin is a significant in vivo inhibitor of activated protein C and low levels of APC:a2M are associated with venous thromboembolism

Navarro S; (...); Medina P

Article. 2018


Adherence to prophylaxis and quality of life in children and adolescents with severe haemophilia A

García-Dasí M; (...); García-Talavera JA

Article. 10.1111/hae.12618. 2015


Adherence to prophylaxis in adult patients with severe haemophilia A

Bonanad, S; (...); Alvarez, M

Meeting Abstract. 2019


Adherence to prophylaxis in adult patients with severe haemophilia A

Bonanad, S; (...); Alvarez, MP

Article. 10.1111/hae.14039. 2020


alpha(2)-Macroglobulin Is a Significant In Vivo Inhibitor of Activated Protein C and Low APC: alpha M-2 Levels Are Associated with Venous Thromboembolism

Martos, L; (...); Medina, P

Article. 10.1055/s-0038-1629902. 2018


Allogeneic hematopoietic cell transplantation in an adult patient with Glanzmann thrombasthenia.

Cid, AR; (...); Sanz, MA

Article. 10.1002/ccr3.1206. 2017


Analysis of 65 pregnancies in 34 women with five different forms of inherited platelet function disorders

Civaschi E; (...); European Haematology Association - Scientific Working Group on Thrombocytopenias

Article. 10.1111/bjh.13458. 2015


Antithrombotic prophylaxis for surgery-associated venous thromboembolism risk in patients with inherited platelet disorders. The SPATA-DVT Study.

Paciullo F; (...); Gresele P

Article. 10.3324/haematol.2019.227876. 2020


Assessment of the thrombin generation assay in haemophilia: comparative study between fresh and frozen platelet-rich plasma.

Vila V; (...); España F

Article. 10.1111/hae.12044. 2013


Association of haplotypes (H) 1 and 3 of the endothelial protein c receptor gene (PROCR) with venous thromboembolism

Bonet, Elena; (...); Espana, Francisco

Article. 10.1016/j.thromres.2012.08.027. 2012


Association of haplotypes (H) 1 and 3 of the endothelial protein C receptor gene (PROCR) with venous thromboembolism

Navarro, S.; (...); Medina, P.

Article. 2013


Bayesian pharmacokinetic individualization of prophylaxis with recombinant factor VIII in severe or moderate hemophilia A

Megias-Vericat, JE; (...); Bonanad, S

Meeting Abstract. 2018


Bayesian pharmacokinetic-guided prophylaxis with recombinant factor VIII in severe or moderate haemophilia A

Megias-Vericat, JE; (...); Poveda, JL

Article. 10.1016/j.thromres.2018.12.027. 2019


Benefits of Ehl Factor VIII Replacement Therapy in Hemophilia: Observations on Coverage, Physical Activity and Phisiotherapy

Querol, Felipe; (...); Bonanad Boix, Santiago

Meeting Abstract. 10.1182/blood-2019-125651. 2019


Bleeding before prophylaxis in severe hemophilia: paradigm shift over two decades

Nijdam A; (...); PedNet and CANAL study groups

Letter. 10.3324/haematol.2014.115709. 2015


Bleeding risk of surgery and its prevention in patients with inherited platelet disorders

Orsini, S; (...); European Hematology Association - Scientific Working Group (EHA-SWG) on thromboc

Article. 10.3324/haematol.2016.160754. 2017


Body Mass Index Best Predicts Recovery of Recombinant Factor VIII in Underweight to Obese Patients with Severe Haemophilia A.

Tiede A; (...); Persson P

Article. 10.1055/s-0039-3400745. 2020


Clinical and molecular characterization by next generation sequencing of Spanish patients affected by congenital deficiencies of fibrinogen.

Moret, A; (...); Bonanad, S

Letter. 10.1016/j.thromres.2019.06.015. 2019


CLINICAL AND MOLECULAR CHARACTERIZATION BY SEQUENCING OF NEW GENERATION OF PATIENTS AFFECTED BY FIBRINOGEN CONGENITAL DEFICIENCIES

Moret, A.; (...); Bonanad, S.

Meeting Abstract. 2019

  • Open Access.

Clinical applicability of the study of platelet function

Vallés J; (...); Santos, MT.

Article. 2014

  • Open Access.

Clinical benefits of a Bayesian model for plasma-derived factor VIII/VWF after one year of pharmacokinetic-guided prophylaxis in severe/moderate hemophilia A patients

Megias-Vericat, JE; (...); Poveda, JL

Article. 10.1016/j.thromres.2021.07.009. 2021


CLINICAL VALIDATION OF THE SPECIFIC POPULATION MODEL OF FACTOR VIII/FVW PLASMA USING WAPPS-HEMO

Megias Vericat, J. E.; (...); Poveda, A. J. L.

Meeting Abstract. 2019

  • Open Access.

COMBINED DEFICIENCY OF PROTEIN C, PROTEIN S AND ANTITHROMBIN IN PATIENTS WITH MESENTERIC OR PORTAL VENOUS THROMBOSIS WITH OR WITHOUT HEPATIC CIRRHOSIS

Martos, L.; (...); Espana, F.

Meeting Abstract. 10.1016/S0049-3848(14)50197-1. 2014


Comparison of a new chemiluminescent immunoassay for von Willebrand factor activity with the ristocetin cofactor-induced platelet agglutination method

Cabrera, N.; (...); Aznar, J. A.

Article. 2013


Comparison of a new chemiluminescent immunoassay for von Willebrand factor activity with the ristocetin cofactor-induced platelet agglutination method.

Cabrera N; (...); Aznar JA

Article. 10.1111/hae.12203. 2013


Comparison of pharmacokinetic estimates using generic and specific population pharmacokinetic models of plasma-derived factor VIII/VWF using WAPPS-Hemo

Megias-Vericat, JE; (...); Poveda, JL

Meeting Abstract. 2020


COMPREHENSIVE LONG-TERM FOLLOW-UP OF PAROXYSMAL NOCTURNAL HEMOGLOBINURIA: A REPORT FROM A SINGLE CENTRE

Sempere, A.; (...); Jarque, I.

Meeting Abstract. 2016

  • Open Access.

Cross-sectional comparative study of pharmacokinetics and efficacy between sucrose-formulated recombinant factor VIII (Kogenate (R)) and BAY 81-8973 (KovaltryA (R)) in patients with severe or moderate haemophilia A in prophylaxis

Megias-Vericat, JE; (...); Poveda, JL

Letter. 10.1111/hae.13733. 2019


Cross-Sectional Comparative Study of PK-Guided Switch between Standard Half-Life and Extended Half-Life Factor VIII Products

Eduardo Megias, Juan; (...); Iorio, Alfonso

Meeting Abstract. 10.1182/blood-2019-127946. 2019


Challenges, questions and opportunities with regard to the new relationship between clinical practice and the haemostasis laboratory: the path towards personalized medicine.

Cid AR

Article. 10.1097/MBC.0000000000001091. 2021


CHARACTERIZATION OF CONGENITAL THROMBOTIC THROMBOCYTOPENIC PURPURA BY MEANS OF IMMUNOLOGICAL AND MOLECULAR TECHNIQUES: RESULTS OF THE GEPTT NATIONAL COLLECTION

Liquori, A.; (...); Gomez-Segui, I

Meeting Abstract. 2019

  • Open Access.

Demographic and baseline data from patients with hemophilia and inhibitors enrolled in the feiba global outcomes ("FEIBA GO") study

Windyga, J; (...); Escuriola-Ettingshausen, C

Meeting Abstract. 2019


DESCRIPTIVE STUDY ON HAEMOPHILIA EXPERIENCE ACQUIRED IN A REFERENCE CENTRE

De la Puerta, R.; (...); Haya Guaita, S.

Meeting Abstract. 2019

  • Open Access.

Determinants of bleeding before and during immune tolerance in 222 boys with severe hemophilia A and inhibitors >5 BU.

Fischer K; (...); Königs C

Article. 10.1182/bloodadvances.2023011442. 2024


Development and testing of a mobile app for systematic collection of patient-reported outcomes (PROs) in patients with hemophilia.

Megias-Vericat, J E; (...); Poveda Andres, J L

Letter. 10.1016/j.thromres.2024.109122. 2024


DIAGNOSIS AND MANAGEMENT OF HEMARTHROSIS AND HAEMOPHILIC ARTHROPATHY USING UNIFIED CLINICAL AND ULTRASOUND CRITERIA: PRELIMINARY RESULTS

Chimeno-Hernandez, A; (...); Querol, F

Meeting Abstract. 2021


DIFFERENT CLINICAL MANIFESTATION OF DYSFIBRINOGENEMIAS ASSOCIATED TO THE MUTATION ARG275 IN EXON 8 OF FGG GENE

Mesa, E.; (...); Bonanad, S.

Meeting Abstract. 10.1016/S0049-3848(14)50268-X. 2014


Efficacy and safety evaluation of Fanhdi ® , a plasma-derived factor VIII/ von Willebrand factor concentrate, in Von Willebrand's disease patients undergoing surgery or invasive procedures: A prospective clinical study.

Jimenez-Yuste, Victor; (...); Paez, Antonio

Letter. 10.1111/hae.14453. 2022


Efficacy of factor IX Grifols(®) in surgery: experience of an international multicentre retrospective study.

Pérez-Garrido R; (...); Rescia V

Letter. 10.1111/j.1365-2516.2012.02919.x. 2012


Emerging viral infections--a potential threat for blood supply in the 21st century.

de Mendoza C; (...); Soriano V

Article. 2012


Emicizumab-induced photosensitivity.

Asensi Canto, Pedro; (...); Haya Guaita, Saturnino

Article. 10.1055/s-0042-1749092. 2022


EVALUATION OF ISTH-BAT IN CONGENITAL PLATELET DISORDERS: CLINICAL, LABORATORY AND MOLECULAR CORRELATION

Bastida, J. M.; (...); Rivera, J.

Meeting Abstract. 2019

  • Open Access.

Evaluation of the effect on endogenous factor VIII activity (FVIII: C) after recombinant von Willebrand factor (rVWF) administration during the elective surgery study in patients with severe von Willebrand disease (VWD)

Mamaev, A; (...); Peyvandi, F

Meeting Abstract. 2018


Factor VIII gene (F8) mutation and risk of inhibitor development in nonsevere hemophilia A.

Eckhardt CL; (...); Fijnvandraat K

Article. 10.1182/blood-2013-02-483263. 2013


Factor VIII products and inhibitor development in severe hemophilia A.

Gouw SC; (...); van den Berg HM

Article. 10.1056/NEJMoa1208024. 2013


Factor XIII deficiency in two Spanish families with a novel variant in gene F13A1 detected by next-generation sequencing; symptoms and clinical management.

Moret A; (...); Bonanad S

Article. 10.1007/s11239-020-02065-z. 2020


FEIBA GLOBAL OUTCOME (FEIBA GO) STUDY: REAL-WORLD DATA IN PATIENTS WITH CONGENITAL HEMOPHILIA AND INHIBITORS

Hermans, C; (...); Windyga, J

Meeting Abstract. 2021


FEIBA GO STUDY: REAL-WORLD BLEEDING FREQUENCY IN INHIBITOR PATIENTS ON PROPHYLAXIS WITH ACTIVATED PROTHROMBIN COMPLEX CONCENTRATES

Ettingshausen, CE; (...); Crea, R

Meeting Abstract. 2018


Functional and molecular characterization of inherited platelet disorders in the Iberian Peninsula: results from a collaborative study

Sánchez-Guiu I; (...); Lozano ML

Article. 10.1186/s13023-014-0213-6. 2014


Haemotrack: Musculoskeletal management in haemophilia with physiotherapist-driven digital solutions

Perez-Alenda, Sofia; (...); Aguilar-Rodriguez, Marta

Meeting Abstract. 2024


Haplotypes of the endothelial protein C receptor gene and circulating protein C levels

Martos, L.; (...); Medina, P.

Article. 2013


Haplotypes of the endothelial protein C receptor gene and circulating protein C levels

Martos, Laura; (...); Espana, Francisco

Article. 10.1016/j.thromres.2012.08.026. 2012


Head-to-head comparison of the pharmacokinetic profiles of a high-purity factor IX concentrate (AlphaNine®) and a recombinant factor IX (BeneFIX®) in patients with severe haemophilia B.

Lissitchkov T; (...); Páez A

Article. 10.1111/hae.12148. 2013


Home-delivered ultrasound monitoring for home treatment of haemarthrosis in haemophilia A

Aznar JA; (...); Bonanad S

Letter. 10.1111/hae.12622. 2015


HYPERPROTEIEMIA AND HYPERFIBRINOLYSIS INCREASED IN PREANESHTESIA STUDY

Guinot Segarra, M.; (...); Luch Garcia, R.

Meeting Abstract. 2019

  • Open Access.

Identification of 58 Mutations (26 Novel) in 94 of 109 Symptomatic Spanish Probands with Protein C Deficiency

Martos, L; (...); Spanish Soc Thrombosis Haemostasis

Article. 10.1055/s-0039-1692440. 2019


Identification of mutations in the protein C gene in a panel of 65 Spanish families with protein C deficiency

Martos, Laura; (...); Espana, Francisco

Article. 10.1016/j.thromres.2012.08.029. 2012


Immune Tolerance Induction in A Patient with Severe Haemophilia A and Factor VIII Inhibitors

Freiria Alberte, C.; (...); Haya Guaita, S.

Meeting Abstract. 2017


IMPACT OF INITIATION OF PROPHYLAXIS, SYNOVITIS AND FUNCTIONALITY ON JOINT HEALTH IN PATIENTS WITH HEMOPHILIA

Chimeno, A.; (...); Bonanad Boix, S.

Meeting Abstract. 2023


Increased circulating dna, calprotectin and mieloperoxidase, as neutrophil extracellular trap markers, are risk factors for deep vein thrombosis

Martos, L.; (...); Medina, P.

Meeting Abstract. 2015


INCREASED LEVELS OF FREE CIRCULATING DNA AND DNASE 1 ACTIVITY IN PLASMA IS ASSOCIATED WITH AN INCREASED RISK OF VENOUS THROMBOEMBOLISM

Oto, J.; (...); Medina, P.

Meeting Abstract. 2019

  • Open Access.

Individualization of prophylaxis with recombinant factor VIII in severe or moderate hemophilia A

Vericat, JEM; (...); Bonanad, S

Meeting Abstract. 2018


Individualized Prophylactic Treatment with Recombinant Factor VIII in Severe or Moderate Haemophilia a Patients. Association Between Pharmacokinetic Parameters and Clinical Variables

Megias-Vericat, Juan Eduardo; (...); Bonanad, Santiago

Meeting Abstract. 10.1182/blood.V128.22.3802.3802. 2016


Inhibitor development after switching of FVIII concentrate in multitransfused patients with severe haemophilia A

Aznar JA; (...); Bonanad S

Article. 10.1111/hae.12439. 2014


Is on-demand treatment effective in patients with severe haemophilia?

Aznar JA; (...); Moret A

Article. 10.1111/j.1365-2516.2012.02806.x. 2012


Kinetics of the interaction between anti-FVIII antibodies and FVIII from therapeutic concentrates, with and without von Willebrand factor, assessed by surface plasmon resonance.

Grancha S; (...); Aznar JA

Article. 10.1111/j.1365-2516.2012.02858.x. 2012


Large deletion in the Factor VIII gene (F8) involving segmental duplications in int22h shows no haematological phenotype in female carriers, but may be embryonic lethal in males.

Casaña P; (...); MARTINEZ, F.

Letter. 10.1111/j.1365-2141.2012.09092.x. 2012


Less common hemorrhagic coagulopathies in women.

Cid AR

Article. 10.1097/MBC.0000000000000990. 2020


Management of acquired hemophilia A: results from the Spanish registry.

Mingot-Castellano ME; (...); Marco P

Article. 10.1182/bloodadvances.2021004626. 2021


Mode of delivery in hemophilia: vaginal delivery and Cesarean section carry similar risks for intracranial hemorrhages and other major bleeds

Andersson, NG; (...); PedNet Haemophilia Res Fdn

Article. 10.3324/haematol.2018.209619. 2019


Moderate and severe haemophilia in Spain: An epidemiological update

Aznar, JA; (...); Lopez, MF

Letter. 10.1111/hae.13462. 2018


Modification of a thrombin generation test to identify new cofactors of the protein C pathway in plasma

Martos, L.; (...); Navarro, S.

Meeting Abstract. 2015


Molecular and clinical profile of von Willebrand disease in Spain (PCM-EVW-ES): comprehensive genetic analysis by next-generation sequencing of 480 patients

Borràs N; (...); Corrales, I

Article. 10.3324/haematol.2017.168765. 2017


Molecular and clinical profile of von Willebrand disease in Spain (PCM-EVW-ES): Proposal for a new diagnostic paradigm

Batlle J; (...); Vidal F

Article. 10.1160/TH15-04-0282. 2016


Monitoring drug activity of dabigatran and rivaroxaban by thrombin generation using the calibrated automated thrombinoscope

Moret, A.; (...); Bonanad, S.

Meeting Abstract. 2015


Mortality caused by intracranial bleeding in non-severe hemophilia A patients

Loomans, JI; (...); Fijnvandraat, K

Article. 10.1111/jth.13693. 2017


National Survey on the Use of Mobile Applications in Patients with Hemophilia and Other Coagulopathies

Eduardo Megias, Juan; (...); Poveda Andres, Jose Luis

Meeting Abstract. 10.1182/blood-2022-169938. 2022


Next generation sequencing in bleeding disorders: two novel variants in the F5 gene (Valencia-1 and Valencia-2) associated with mild factor V deficiency.

Moret, A; (...); Bonanad, S

Article. 10.1007/s11239-019-01911-z. 2019


Nosocomial fungemia by Candida auris: First four reported cases in continental Europe

Ruiz Gaitan, Alba Cecilia; (...); Peman, Javier

Article. 10.1016/j.riam.2016.11.002. 2017


Novel mutations in RASGRP2, which encodes CalDAG-GEFI, abrogate Rap1 activation, causing platelet dysfunction

Lozano ML; (...); Rivera J

Article. 10.1182/blood-2015-11-683102. 2016


Patient and treatment related factors and inhibitor development after 50 exposure days in patients with non-severe hemophilia A-preliminary data of a nested case-control study

Abdi, A; (...); INSIGHT Study Grp

Meeting Abstract. 2019


PATIENT WITH CONGENITAL AFIBRINOGENEMIA AND PERIPHERAL ARTERIAL THROMBOSIS. THERAPEUTIC ANTITHROMBOTIC MANAGEMENT BASED ON MONITORING

Moscardo, A.; (...); Valles, J.

Meeting Abstract. 10.1016/S0049-3848(14)50371-4. 2014


Pharmacokinetic and clinical improvements after PK-guided switch from standard half-life to extended half-life factor VIII products.

Megias-Vericat, J. E.; (...); Poveda Andres, J. L.

Article. 10.1016/j.thromres.2022.06.001. 2022


Phase 3 study of recombinant von Willebrand factor in patients with severe von Willebrand disease who are undergoing elective surgery

Peyvandi, F; (...); Sytkowski, A

Article. 10.1111/jth.14313. 2019


Physical Activity In Haemophilia: Hemorrhagic Risk And Factor Levels (myPKFiT)

Querol-Fuentes, F; (...); Bonanad, S

Meeting Abstract. 2017


PK-GUIDED SWITCH BETWEEN STANDARD HALF-LIFE AND EXTENDED HALF-LIFE FACTOR VIII PRODUCTS

Vericat, JEM; (...); Iorio, A

Meeting Abstract. 2020


PK-guided switch from standard half-life to extended half-life factor VIII products

Megias-Vericat, JE; (...); Iorio, Alfonso

Meeting Abstract. 2020


Practical guide to emergency treatment of thrombotic microangiopathy

Romero S; (...); Grupo de Microangiopatía Trombótica del Hospital Universitario y Politécnico La

Editorial Material. 10.1016/j.medcli.2018.01.013. 2018


Predictive factors of immune tolerance treatment response in severe haemophilia A patients with inhibitors: A real-world report from a single centre, mixed retrospective-prospective long-term study

Haya, S; (...); Casana, P

Letter. 10.1111/hae.13660. 2019


Prophylactic treatment in hemophilic patients with inhibitors.

Haya S

Article. 10.1097/MBC.0000000000000823. 2019


Prospective surveillance study of haemophilia A patients switching from moroctocog alfa or other factor VIII products to moroctocog alfa albumin-free cell culture (AF-CC) in usual care settings

Parra Lopez R; (...); Rendo P

Article. 10.1160/TH14-09-0760. 2015


Quality of thawed plasma inactivated with methylene blue after 48-hour storage

Balaguer A; (...); Sanz MÁ

Letter. 10.1016/j.transci.2014.11.005. 2015


Real World Bleeding Frequency in Patients with Inhibitors on Prophylaxis with Feiba: First Data Read-Out Of Feiba Global Outcome Study (FEIBA GO)

Escuriola-Ettingshausen, C; (...); Crea, R

Meeting Abstract. 2017


Real-world analysis of the PK-guided switch from standard half-life factor VIII to efmoroctocog alfa.

Megias-Vericata, J. E.; (...); Poveda Andres, J L

Letter. 10.1016/j.thromres.2023.11.023. 2023


Real-world bleeding frequency in inhibitor patients on prophylaxis with apcc: data read-out of the "feiba global outcomes study (FEIBA GO)"

Ettingshausen, CE; (...); Crea, R

Meeting Abstract. 2018


Real-World Clinical Management of Patients with Hemophilia and Inhibitors: Effectiveness and Safety of aPCC in Patients with > 18 Months' Follow-up in the FEIBA Global Outcome Study (FEIBA GO)

Windyga, Jerzy; (...); Escuriola, Carmen

Meeting Abstract. 10.1182/blood-2019-124324. 2019


Real-world data in patients with congenital hemophilia and inhibitors: final data from the FEIBA Global Outcome (FEIBA GO) study.

Ettingshausen CE; (...); Windyga J

Article. 10.1177/20406207231184323. 2023


REAL-WORLD EFFICACY AND SAFETY DATA OF PATIENTS WITH HEMOPHILIA AND INHIBITORS TREATED WITH APCC: "FEIBA GLOBAL OUTCOME STUDY (FEIBA-GO)", RESULTS FROM > 12 MONTHS FOLLOW-UP

Windyga, J; (...); Escuriola-Ettinghausen, C

Meeting Abstract. 2019

  • Open Access.

RFVIIIFC FOR FIRST-TIME IMMUNE TOLERANCE INDUCTION (ITI) THERAPY: INTERIM RESULTS FROM THE GLOBAL, PROSPECTIVE VERITI-8 STUDY

Malec, L; (...); Peyvandi, F

Meeting Abstract. 2019

  • Open Access.

Risk Factors for the Progression from Low to High Titres in 260 Children with Severe Haemophilia A and Newly Developed Inhibitors

Mancuso, ME; (...); European Pediatric Network for Haemophilia Management (PedNet) the REMAIN (REal

Article. 10.1160/TH17-01-0059. 2017


Role of multimeric analysis of von Willebrand factor (VWF) in von Willebrand disease (VWD) diagnosis: Lessons from the PCM-EVW-ES Spanish project

Perez-Rodriguez, A; (...); Lopez-Fernandez, MF

Article. 10.1371/journal.pone.0197876. 2018


Secondary prophylaxis vs. on-demand treatment to improve quality of life in severe adult haemophilia A patients: a prospective study in a single centre

Aznar JA; (...); Querol F

Article. 10.1111/vox.12066. 2014


Spanish consensus guidelines on prophylaxis with bypassing agents for surgery in patients with haemophilia and inhibitors

Mingot-Castellano, ME; (...); Sedano-Balbas, C

Review. 10.1111/ejh.12730. 2016


Spanish Consensus Guidelines on prophylaxis with bypassing agents in patients with haemophilia and inhibitors

Lopez-Fernandez, MF; (...); Balbas, CS

Article. 10.1160/TH15-07-0568. 2016


SWITCH ANALYSIS GUIDED BY PHARMACOKINETICS FROM FACTORS VIII OF STANDARD HALF LIFE TO EXTENDED HALF LIFE FACTORS

Megias Vericat, J. E.; (...); Poveda, A. J. L.

Meeting Abstract. 2019

  • Open Access.

The changing face of immune tolerance induction in haemophilia A with the advent of emicizumab

Carcao, M; (...); Future Immunotolerance Treatment

Article. 10.1111/hae.13762. 2019


The ISTH bleeding assessment tool as predictor of bleeding events in inherited platelet disorders: Communication from the ISTH SSC Subcommittee on Platelet Physiology

Gresele, P; (...); BAT-VAL Study Investigators

Article. 10.1111/jth.15263. 2021


THROMBIN GENERATION TEST IN PATIENTS UNDER NEW ORAL ANTICOAGULANTS (DABIGATRAN AND RIVAROXABAN)

Cabrera, N.; (...); Bonanad, S.

Meeting Abstract. 10.1016/S0049-3848(14)50148-X. 2014


Type 2N VWD: Conclusions from the Spanish PCM-EVW-ES project

Perez-Rodriguez, Almudena; (...); Lopez-Fernandez, Maria Fernanda

Article. 10.1111/hae.14405. 2021


Unraveling the effect of silent, intronic and missense mutations on VWF splicing: contribution of next generation sequencing in the study of mRNA

Borras, N; (...); Corrales, I

Article. 10.3324/haematol.2018.203166. 2019


Unraveling the Influence of Common von Willebrand factor variants on von Willebrand Disease Phenotype: An Exploratory Study on the Molecular and Clinical Profile of von Willebrand Disease in Spain Cohort

Borras, N; (...); Vidal, F

Article. 10.1055/s-0040-1702227. 2020


Until what age should we worry about inhibitors? New data from the PedNet Registry on 1,038 PUPs with severe hemophilia a followed from the first until over 1,000 exposure days

van den Berg, M; (...); PedNet Study Grp

Meeting Abstract. 2019


Update on Molecular Testing in von Willebrand Disease

Batlle, J; (...); PCM-EVW-ES Investigators Team

Review. 10.1055/s-0039-1679922. 2019


Validation of the ISTH/SSC bleeding assessment tool for inherited platelet disorders: A communication from the Platelet Physiology SSC.

Gresele P; (...); BAT-VAL study investigators

Article. 10.1111/jth.14683. 2020


Variation in baseline factor VIII concentration in a retrospective cohort of mild/moderate hemophilia A patients carrying identical F8 mutations

Loomans, JI; (...); Fijnvandraat, K

Article. 10.1111/jth.13581. 2017


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