ESTUDIO ALEATORIZADO, DOBLE CIEGO, CONTROLADO CON PLACEBO PARA INVESTIGAR LA EFICACIA DEL TRATAMIENTO CRONICO DE INTERMITENTE CON MOXIFLOXACINO EN LA PREVENCION DE EXACERVACIONES AGUDAS DE BRONQUITIS CRONICA EN PACIENTES AMBULATORIOS

Datos básicos

Protocolo:
BAY12-8039-11229
EUDRACT:
2004-000404-40
NCT:
Centro:
Año de incio:
Año de finalización:
ENSAYO CLÍNICO

Documentos

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Participantes

Grupos

Financiadores - Promotores

QUIMICA FARMACEUTICA BAYER S.L.

Resultados del Ensayo Clínico


Acute and sustained endothelial damage in COVID-19

Mendez, Raul; (...); Menendez, Rosario

Meeting Abstract. 10.1183/13993003.congress-2021.OA3966. 2021


Acute and sustained increase in endothelial biomarkers in COVID-19.

Méndez R; (...); Menéndez R

Article. 10.1136/thoraxjnl-2020-216797. 2021

  • Open Access.

BACTERAEMIC PNEUMOCOCCAL PNEUMONIA AND SARS-CoV-2 PNEUMONIA: DIFFERENCES AND SIMILARITIES.

Fernández LS; (...); Jorge RZ

Article. 10.1016/j.ijid.2021.11.023. 2022

  • Open Access.

Baricitinib against severe COVID-19: effectiveness and safety in hospitalised pretreated patients.

Iglesias Gómez R; (...); Poveda Andrés JL

Article. 10.1136/ejhpharm-2021-002741. 2021

  • Open Access.

Basic host response parameters to classify mortality risk in COVID-19 and community-acquired pneumonia

Menendez, Rosario; (...); Torres, Antoni

Article. 10.1038/s41598-024-62718-4. 2024

  • Open Access.

Blood Neutrophil Counts Define Specific Clusters of Bronchiectasis Patients: A Hint to Differential Clinical Phenotypes.

Wang X; (...); Barreiro E

Article. 10.3390/biomedicines10051044. 2022

  • Open Access.

Cardiovascular Events during and after Bronchiectasis Exacerbations and Long-Term Mortality.

Méndez R; (...); Menéndez R

Article. 10.1016/j.chest.2021.10.013. 2021


COVID-19 in young and middle aged adults. Predictors of poor evolution and clinical differences

Tabernero Huguet, Eva; (...); Zalacain Jorge, Rafael

Meeting Abstract. 10.1183/13993003.congress-2021.OA88. 2021


COVID-19 in young and middle-aged adults: predictors of poor outcome and clinical differences

Tabernero E; (...); Zalacain R

Article. 10.1007/s15010-021-01684-9. 2021

  • Open Access.

COVID-19 Patients Benefitting From Remdesivir for Improved Survival: A Neural Network-Based Approach.

Garcia-Vidal, Carolina; (...); Soriano, Alex

Article. 10.1002/jmv.70276. 2025


Criteria and definitions for the radiological and clinical diagnosis of bronchiectasis in adults for use in clinical trials: international consensus recommendations.

Aliberti S; (...); Chalmers JD

Article. 10.1016/S2213-2600(21)00277-0. 2021


Differences in Nutritional Status and Inflammatory Biomarkers between Female and Male Patients with Bronchiectasis: A Large-Cohort Study

Wang, XJ; (...); Barreiro, E

Article. 10.3390/biomedicines9080905. 2021

  • Open Access.

Early profiling of low-risk SARS-CoV-2 pneumonia for ward allocation

Mendez, Raul; (...); Menendez, Rosario

Meeting Abstract. 10.1183/13993003.congress-2021.PA3659. 2021


Early recognition of low-risk SARS-CoV-2 pneumonia: A model validated with initial data and IDSA/ATS minor criteria.

Menendez, Rosario; (...); Torres, Antoni

Article. 10.1016/j.chest.2022.05.013. 2022

  • Open Access.

Endothelial Biomarkers Are Superior to Classic Inflammatory Biomarkers in Community-Acquired Pneumonia.

González-Jiménez P; (...); Méndez R

Article. 10.3390/biomedicines12102413. 2024

  • Open Access.

Endothelial Damage, Neutrophil Extracellular Traps and Platelet Activation in COVID-19 vs. Community-Acquired Pneumonia: A Case-Control Study.

González-Jiménez P; (...); Menéndez R

Article. 10.3390/ijms241713194. 2023

  • Open Access.

Expert Consensus: Main Risk Factors for Poor Prognosis in COVID-19 and the Implications for Targeted Measures against SARS-CoV-2.

Candel, Francisco Javier; (...); On Behalf Of The Modus Investigators Adenda

Article. 10.3390/v15071449. 2023

  • Open Access.

Factors Associated With One-Year Mortality in Hospitalised Patients With Exacerbated Bronchiectasis.

Scioscia, G.; (...); Torres, A.

Article. 10.1016/j.arbres.2022.04.008. 2022


Herpes Zoster Virus: Should Patients With Chronic Respiratory Diseases Be Vaccinated?

Menendez, Rosario, Gonzalez-Jimenez, Paula, Mendez, Raul

Editorial Material. 10.1016/j.arbres.2023.07.012. 2023

  • Open Access.

Immune treatment in COVID-19.

Menendez, Rosario; (...); Mendez, Raul

Article. 10.37201/req/s01.14.2022. 2022

  • Open Access.

Impact of Chronic Bronchial Infection by Staphylococcus aureus on Bronchiectasis.

Garcia Clemente, Marta; (...); Martínez-García MÁ

Article. 10.3390/jcm11143960. 2022

  • Open Access.

Impact of outdoor air pollution on severity and mortality in COVID-19 pneumonia.

Bronte, O.; (...); Espana, P. P.

Article. 10.1016/j.scitotenv.2023.164877. 2023

  • Open Access.

Impact of Time to Intubation on Mortality and Pulmonary Sequelae in Critically Ill COVID-19 Patients: A Prospective Cohort

Gonzalez, J.; (...); Barbe, F.

Meeting Abstract. 2022


Impact on in-hospital mortality of Ceftaroline versus standard of care in Community-Acquired Pneumonia: A Propensity Matched Analysis

Campos, Catia Cilloniz; (...); Soriano, Alex

Meeting Abstract. 10.1183/13993003.congress-2021.PA1753. 2021

  • Open Access.

Impact on in-hospital mortality of ceftaroline versus standard of care in community-acquired pneumonia: a propensity-matched analysis.

Cilloniz, Catia; (...); Soriano, Alex

Article. 10.1007/s10096-021-04378-0. 2022

  • Open Access.

Initial and Residual Cardiovascular Damage Remaining at Day 30 in Community-acquired Pneumonia

Ocana, R. Mendez; (...); Menendez, R.

Meeting Abstract. https://doi.org/10.1164/ajrccm-conference.2024.209.1_MeetingAbstracts.A6241. 2024

  • Open Access.

Is the long-term mortality similar in COVID-19 and community-acquired pneumonia?

Mendez, Raul; (...); NEUMONAC and RECOVID

Article. 10.3389/fmed.2023.1236142. 2023

  • Open Access.

Key Factors Associated With Pulmonary Sequelae in the Follow-Up of Critically Ill COVID-19 Patients.

González J; (...); Barbé F

Article. 10.1016/j.arbres.2022.12.017. 2023

  • Open Access.

K-Means Clustering Identifies Diverse Clinical Phenotypes in COVID-19 Patients: Implications for Mortality Risks and Remdesivir Impact.

Garcia-Vidal C; (...); Soriano A

Article. 10.1007/s40121-024-00938-x. 2024

  • Open Access.

Late Breaking Abstract - Incidence, risk factors and thrombotic load of pulmonary embolism in patients hospitalized with COVID-19

Bekki, Amina; (...); Angel Martinez-Garcia, Miguel

Meeting Abstract. 10.1183/13993003.congress-2021.OA2597. 2021


Long-term Mortality in COVID-19 and Community-Acquired Pneumonia: A One-year Follow-up Study

Ocana, R. Mendez; (...); NEUMONAC RECOVID

Meeting Abstract. 2023


Long-term neuropsychiatric outcomes in COVID-19 survivors: A 1-year longitudinal study.

Mendez, Raul; (...); Menendez, Rosario

Letter. 10.1111/joim.13389. 2022

  • Open Access.

Machine-Learning Model for Mortality Prediction in Patients with Community-acquired Pneumonia: Development and validation study.

Cilloniz, Catia; (...); Torres, Antoni

Article. 10.1016/j.chest.2022.07.005. 2022


Neutrophil Extracellular Traps and Platelet Activation for Identifying Severe Episodes and Clinical Trajectories in COVID-19

González-Jiménez P; (...); Menéndez R

Article. 10.3390/ijms24076690. 2023

  • Open Access.

Obtaining patient phenotypes in SARS-CoV-2 pneumonia, and their association with clinical severity and mortality

Garcia-Garcia, Fernando; (...); Jorge, Rafael Zalacain

Article. 10.1186/s41479-024-00132-0. 2024

  • Open Access.

Persistent Respiratory Failure and Re-Admission in Patients with Chronic Obstructive Pulmonary Disease Following Hospitalization for COVID-19

Figueira-Goncalves, Juan Marco; (...); Menendez, Rosario

Article. 10.2147/COPD.S428316. 2023

  • Open Access.

Phenotypic Clustering in Non-Cystic Fibrosis Bronchiectasis Patients: The Role of Eosinophils in Disease Severity

Wang, XJ; (...); Barreiro, E

Article. 10.3390/ijerph18168431. 2021

  • Open Access.

Pneumococcal Serotypes Associated with Community-Acquired Pneumonia Hospitalizations in Adults in Spain, 2016-2020: The CAPA Study

Menendez, Rosario; (...); Gessner, Bradford D.

Article. 10.3390/microorganisms11112781. 2023

  • Open Access.

Prognostic implications of comorbidity patterns in critically ill COVID-19 patients: A multicenter, observational study.

Benítez ID; (...); Barbé F

Article. 10.1016/j.lanepe.2022.100422. 2022

  • Open Access.

Residual pulmonary infiltrates, symptoms and diffusion impairment at one-year after severe COVID-19 infection have different associated factors.

Menendez, Rosario; (...); Torres, Antoni

Article. 10.1111/joim.13642. 2023

  • Open Access.

Systemic Inflammatory Biomarkers Define Specific Clusters in Patients with Bronchiectasis: A Large-Cohort Study.

Wang X; (...); Barreiro E

Article. 10.3390/biomedicines10020225. 2022

  • Open Access.

Ten Issues for Updating in Community-Acquired Pneumonia: An Expert Review.

Candel, Francisco Javier; (...); Serrano, Leyre

Article. 10.3390/jcm12216864. 2023

  • Open Access.

The evolution and distribution of pneumococcal serotypes in adults hospitalized with community acquired pneumonia in Spain using serotype specific urinary antigen detection test: the CAPA study, 2011-2018.

Torres, Antoni; (...); Gessner, Bradford D

Article. 10.1093/cid/ciab307. 2021

  • Open Access.

Treatment Failure and Clinical Stability in Severe Community-Acquired Pneumonia.

Méndez R; (...); Menéndez R

Article. 10.1055/s-0043-1778139. 2024


Understanding the Host in the Management of Pneumonia An Official American Thoracic Society Workshop Report

Dela Cruz, Charles S.; (...); Amer Thoracic Soc Assembly Pulm In

Article. 10.1513/AnnalsATS.202102-209ST. 2021

  • Open Access.

Validation of IDSA/ATS Guidelines for ICU Admission in Adults Over 80 Years Old With Community-Acquired Pneumonia.

Cilloniz, Catia; (...); Torres, Antoni

Article. 10.1016/j.arbres.2022.08.012. 2023

  • Open Access.

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