Portal de investigación
Desarrollo e implementación de un algoritmo basado en inteligencia artificial para la selección de embriones desvitrificados a partir de datos morfológicos, morfocinéticos y secretómicos
Datos básicos
- Código:
- CIACIF/2021/019
- Protocolo:
- CIACIF/2021/019
- EUDRACT:
- NCT:
- Centro:
- Dotación:
- 93.878,00 €
- Año de incio:
- 2022
- Año de finalización:
- 2026
Documentos
- No hay documentos
Participantes
Financiadores - Promotores
Resultados del Ensayo Clínico
A Combination of Artificial Intelligence with Genetic Algorithms on Static Time-Lapse Images Improves Consistency in Blastocyst Assessment, An Interpretable Tool to Automate Human Embryo Evaluation: A Retrospective Cohort Study
Toschi, Marco; (...); Meseguer, Marcos
Article. 10.22074/ijfs.2024.2008339.1510. 2024
A foundation model for embryology trained on time-lapse images
Rajendran, S.; (...); Hajirasouliha, I.
Meeting Abstract. https://doi.org/10.1093/humrep/deae108.378. 2024
A NON-INVASIVE ARTIFICIAL INTELLIGENCE (AI) ALGORITHM FOR ASSESSING EUPLOIDY OF BLASTOCYSTS CAN BE USED TO PREDICT LIVE BIRTH REGARDLESS OF WHETHER PGT-A WAS PERFORMED.
VerMilyea, M. D.; (...); Perugini, M.
Meeting Abstract. 10.1016/j.fertnstert.2024.05.123. 2024
A non-invasive artificial intelligence approach for the prediction of human blastocyst ploidy: a retrospective model development and validation study.
Barnes, Josue; (...); Hajirasouliha, Iman
Article. 10.1016/S2589-7500(22)00213-8. 2023
A Randomized Controlled Intervention Trial with Danazol to Improve Telomeric and Fertility Parameters in Women with Diminished Ovarian Reserve: A Pilot Study
Cordova-Oriz, Isabel; (...); Garcia-Velasco, Juan A.
Article. 10.1089/whr.2023.0013. 2023
Advancements and Challenges in Preimplantation Genetic Testing for Aneuploidies: In the Pathway to Non-Invasive Techniques
del Arco de la Paz, Ana; (...); Galliano, Daniela
Review. 10.3390/genes15121613. 2024
Analysis of oocyte morphology: differences between rescued and non-rescued metaphase II oocytes after conventional ovarian hyperstimulation
Carrion, T.; (...); Meseguer, M.
Meeting Abstract. https://doi.org/10.1093/humrep/deae108.577. 2024
Application of a methodological framework for the development and multicenter validation of reliable artificial intelligence in embryo evaluation
Gilboa, D.; (...); Seidman, D. S.
Article. 10.1186/s12958-025-01351-w. 2025
Artificial intelligence algorithms in assisted reproduction: differences in the evaluation of embryos from fresh or vitrified donor oocytes
Murria, L.; (...); Cobo, A.
Meeting Abstract. 2023
ARTIFICIAL INTELLIGENCE CLARIFIES LOW-LEVEL MOSAIC FINDINGS IN PREIMPLANTATION GENETIC TESTING FOR ANEUPLOIDY
Gimenez-Rodriguez, Carla; (...); Meseguer, Marcos
Meeting Abstract. 10.1016/j.fertnstert.2024.07.989. 2024
ARTIFICIAL INTELLIGENCE NEURAL NETWORK TRAINED WITH POST-THAW TIME-LAPSE MORPHOKINETICS AND PROTEOMIC PROFILE FROM SPENT CULTURE MEDIA PREDICTS PREGNANCY IN WARMED BLASTOCYSTS.
Conversa Martinez, Laura; (...); Meseguer, Marcos
Meeting Abstract. 10.1016/j.fertnstert.2024.07.551. 2024
ASSESSING PRE- AND POST-INTRACYTOPLASMIC SPERM INJECTION (ICSI) OOCYTE IMAGES WITH ARTIFICIAL INTELLIGENCE (AI): PREDICTING FERTILIZATION AND BLASTOCYST DEVELOPMENT.
Murria, Lucia; (...); Meseguer, Marcos
Meeting Abstract. 10.1016/j.fertnstert.2024.07.552. 2024
Autologous stem cell ovarian transplant induced long-lasting effects on the plasma proteome of women with premature ovarian insufficiency
Buigues, A.; (...); Herraiz, S.
Meeting Abstract. 2023
Automated embryo assessment: a simple web application correlates scores with embryo morphology, developmental velocity, ploidy, and clinical outcomes
Rodriguez, C. Albert; (...); Meseguer, M.
Meeting Abstract. https://doi.org/10.1093/humrep/deae108.574. 2024
AUTOMATED REAL-TIME SPERM SELECTION FOR INTRACYTOPLASMIC SPERM INJECTION (ICSI): SIBLING OOCYTE EVALUATION
Carrion Sisternas, Laura; (...); Meseguer, Marcos
Meeting Abstract. 2024
Automatic ploidy prediction and quality assessment of human blastocysts using time-lapse imaging
Rajendran, Suraj; (...); Hajirasouliha, Iman
Article. 10.1038/s41467-024-51823-7. 2024
Automatic Ploidy Prediction and Quality Assessment of Human Blastocysts Using Time-Lapse Imaging
Rajendran, Suraj; (...); Hajirasouliha, Iman
Editorial Material. 10.1097/01.ogx.0001096656.39837.23. 2024
Better late than never: the clinical value of Day 7 blastocysts.
Fraire-Zamora, Juan J.; (...); Liperis, George
Article. 10.1093/humrep/deac269. 2023
Can Microfluidics Improve Sperm Quality? A Prospective Functional Study.
Meseguer, Fernando; (...); Meseguer, Marcos
Article. 10.3390/biomedicines12051131. 2024
Can we predict blastulation, implantation and live birth in early stages of embryo development? Clinical validation of a classification algorithm based on automatic morphokinetic annotations
Aparicio Ruiz, B.; (...); Meseguer, M.
Meeting Abstract. 2023
CELL-FREE DNA LEVELS IN SPENT IVF CULTURE MEDIUM: ASSESSING CORRELATIONS WITH EMBRYO MORPHOLOGY AND CHROMOSOMAL INTEGRITY
Gimenez-Rodriguez, Carla; (...); Meseguer, Marcos
Meeting Abstract. 2024
Clinical validation of an automatic classification algorithm applied on cleavage stage embryos: analysis for blastulation, euploidy, implantation, and live-birth potential.
Valera, M. A.; (...); Meseguer, M.
Article. 10.1093/humrep/dead058. 2023
Combination of proteomics and automatic scoring using artificial neural networks to detect aneuploid embryos
Bosch, E. Paya; (...); Meseguer, M.
Meeting Abstract. 2023
CONTRACTIONS AFTER BLASTOCYST VITRIFICATION-WARMING: SHRINKAGE RATE AND TIMING CORRELATE WITH ONGOING PREGNANCY.
Conversa Martinez, Laura; (...); Meseguer, Marcos
Meeting Abstract. 10.1016/j.fertnstert.2024.07.748. 2024
Corticosteroids, androgens, progestogens and oestrogens in the endometrial microenvironment, and their association with endometrial progression and function
Marti-Garcia, Diana; (...); Diaz-Gimeno, Patricia
Article. 10.1016/j.rbmo.2024.104377. 2024
Deep learning system for classification of ploidy status using time-lapse videos.
Paya, Elena; (...); Meseguer, Marcos
Article. 10.1016/j.xfss.2023.06.002. 2023
DEVELOPMENT OF A NON-INVASIVE ARTIFICIAL INTELLIGENCE ALGORITHM FOR IDENTIFICATION OF EUPLOID EMBRYOS WITH HIGH MORPHOLOGICAL QUALITY DURING IVF.
VerMilyea, Matthew; (...); Pergini, Michelle
Meeting Abstract. 2023
DEVELOPMENT OF AN AUTOMATED SYSTEM FOR MORPHOLOGICAL CLASSIFICATION OF EMBRYOS USING IMAGE-BASED ARTIFICIAL INTELLIGENCE.
Hall, Jonathan Mm.; (...); Perugini, Michelle
Meeting Abstract. 2023
DEVELOPMENT OFAN ARTIFICIAL INTELLIGENCE MODEL SPECIFICALLY DESIGNED AND TRAINED WITH VITRIFIED-WARMED BLASTOCYST IMAGES: IMPLANTATION PREDICTION IN FROZEN CYCLES.
Perez-Albala, Sonia; (...); Meseguer, Marcos
Meeting Abstract. 10.1016/j.fertnstert.2024.07.549. 2024
Do culture conditions alter the efficacy of embryo selection algorithms using time-lapse technology? Development of novel embryo selection model with embryos cultured in different conditions
Valera, M. A.; (...); Meseguer, M.
Meeting Abstract. 2023
Endometrial cortisol and estradiol levels as indicators of pregnancy prognosis and their association with State-Trait Anxiety Inventory (STAI) psychological questionnaire punctuations in IVF patients
Marti-Garcia, D.; (...); Diaz-Gimeno, P.
Meeting Abstract. 2023
Ensuring no clinical risk: a cohort analysis on the agreement between the embryo selected by the embryologist and the embryo selected by artificial intelligence
Bori, L.; (...); Meseguer, M.
Meeting Abstract. 2023
External validation of a fully automated evaluation tool: a retrospective analysis on 68,471 scored embryos.
Bori L; (...); Meseguer M
Article. 10.1016/j.fertnstert.2024.10.006. 2024
IMPROVING BLASTULATION WITH AI-POWERED REAL-TIME MOTILITY ANALYSIS OF SINGLE SPERM DURING ICSI
Paredes, Omar; (...); Cohen, Jacques
Meeting Abstract. 10.1016/j.fertnstert.2024.08.102. 2024
Kit Ligand Depletion Reverts the Positive Effects of Plasma Rich in Both Stem Cell-Secreted and Platelet-Enclosed Factors on Ovulation and Ovarian Niche
Buigues, Anna; (...); Herraiz, Sonia
Meeting Abstract. 2023
Machine learning tool for predicting mature oocyte yield and trigger day from start of stimulation: towards personalized treatment.
Garg, Akhil; (...); Meseguer, Marcos
Article. 10.1016/j.rbmo.2024.104441. 2024
Morphokinetic analysis and implantation prediction of embryos derived from oocytes microinjected with Artificial Intelligence (AI) real-time assessed sperm
Beltran Torregrosa, D.; (...); Meseguer, M.
Meeting Abstract. https://doi.org/10.1093/humrep/deae108.425. 2024
OOCYTE ASSESSMENT BASED ON ARTIFICIAL INTELLIGENCE (AI) FOR THE PREDICTION OF BLASTOCYST DEVELOPMENT: A COMPARATIVE ANALYSIS OF FRESH AND VITRIFIED DONOR OOCYTES
Murria, Lucia; (...); Cobo, Ana
Meeting Abstract. 10.1016/j.fertnstert.2024.08.093. 2024
OOCYTE ASSESSMENT BASED ON ARTIFICIAL INTELLIGENCE (AI). ARE OOCYTE SCORES RELATED TO SUBSEQUENT EMBRYO QUALITY?
Murria, Lucia; (...); Meseguer, Marcos
Meeting Abstract. 2024
Optimizing oocyte donor stimulation: A revelation from 2,666 cases emphasizing the sole efficacy of exogenous FSH
Aparicio Ruiz, B.; (...); Meseguer, M.
Meeting Abstract. https://doi.org/10.1093/humrep/deae108.1025. 2024
Precise quantification of DNA in spent culture media sheds light on associations between DNA quantity, embryonic ploidy status and morphological quality
Savash, M.; (...); Wells, D.
Meeting Abstract. https://doi.org/10.1093/humrep/deae108.870. 2024
Predicting Embryo Ploidy Status Using Time-lapse Images
Rajendran, S.; (...); Hajirasouliha, I.
Meeting Abstract. 2023
Predicting fetal heartbeat in vitrified blastocysts through artificial intelligence analysis of post-warming images and videos
Conversa Martinez, L.; (...); Meseguer, M.
Meeting Abstract. https://doi.org/10.1093/humrep/deae108.522. 2024
Quantity or quality? Comparative study on the effectiveness of recombinant, purified and mixed gonadotropins on the outcome of ICSI treatments from an embryologist perspective
Valera, M. A.; (...); Meseguer, M.
Meeting Abstract. https://doi.org/10.1093/humrep/deae108.943. 2024
Sex-dependent discrepancies in automatic scoring: implications for the performance of embryo evaluation and selection methods
Bori, L.; (...); Meseguer, M.
Meeting Abstract. https://doi.org/10.1093/humrep/deae108.380. 2024
Should embryo rebiopsy be considered a regular strategy to increase the number of embryos available for transfer?
Nohales, Mar; (...); de los Santos, Maria Jose
Article. 10.1007/s10815-023-02875-z. 2023
SIMULATED COHORTANALYSES SHOWED THATAN AUTOMATIC ARTIFICIAL INTELLIGENCE (AI) SCORE REDUCED THE NUMBER OF CYCLES NEEDED TO ACHIEVE LIVE BIRTH AND INCREASED THE FIRST-CYCLE SUCCESS RATES
Gimenez, Carla; (...); Meseguer, Marcos
Meeting Abstract. 2023
Single-cell multi-omic analysis profiles defective genome activation and epigenetic reprogramming associated with human pre-implantation embryo arrest.
Hernandez Mora, Jose Ramon; (...); Monk, David
Article. 10.1016/j.celrep.2023.112100. 2023
State-Trait Anxiety Inventory (STAI) punctuations as a non-invasive method for evaluating endometrial prognosis associated with cortisol and estradiol endometrial levels in IVF patients
Marti-Garcia, D.; (...); Diaz-Gimeno, P.
Meeting Abstract. https://doi.org/10.1093/humrep/deae108.817. 2024
Systemic changes induced by autologous stem cell ovarian transplant in plasma proteome of women with impaired ovarian reserves.
Buigues, Anna; (...); Herraiz, Sonia
Article. 10.18632/aging.205400. 2023
Testing an artificial intelligence algorithm to predict fetal heartbeat of vitrified-warmed blastocysts from a single image: predictive ability in different settings.
Conversa L; (...); Meseguer M
Article. 10.1093/humrep/deae178. 2024
TESTING THE ABILITY OF AN ARTIFICIAL INTELLIGENCE (AI) ALGORITHM IN PREDICTING IMPLANTATION AND ONGOING PREGNANCY POTENTIAL OF VITRIFIED-WARMED BLASTOCYSTS FROM A SINGLE IMAGE
Conversa Martinez, Laura; (...); Meseguer, Marcos
Meeting Abstract. 2023
The patient or the blastocyst; which leads to the perfect outcome prediction?
Giménez-Rodríguez C, Meseguer M
Editorial Material. 10.1016/j.fertnstert.2023.08.011. 2023
Time-Lapse Imaging. Morphokinetic analysis of In Vitro Fertilization outcomes.
Gimenez, Carla; (...); Meseguer, Marcos
Article. 10.1016/j.fertnstert.2023.06.015. 2023
Undisturbed culture: a clinical examination of this culture strategy on embryo in vitro development and clinical outcomes.
Valera MÁ; (...); Meseguer M
Article. 10.1016/j.fertnstert.2024.07.018. 2024
USE OF ARTIFICIAL INTELLIGENCE FOR PREDICTING LIVE BIRTH IN VITRIFIED BLASTOCYST CYCLES
Coello, Aila; (...); Meseguer, Marcos
Meeting Abstract. 10.1016/j.fertnstert.2024.07.812. 2024
Using artificial intelligence platform coupled to an existing time system; external validation of an automatic embryo score to assist in selection
Perez Albala, S.; (...); Bellver, J.
Meeting Abstract. 2023
Using Unlabeled Information of Embryo Siblings from the Same Cohort Cycle to Enhance In Vitro Fertilization Implantation Prediction.
Tzukerman, Noam; (...); Zaritsky, Assaf
Article. 10.1002/advs.202207711. 2023
Visual interpretability of image-based classification models by generative latent space disentanglement applied to in vitro fertilization
Rotem, Oded; (...); Zaritsky, Assaf
Article. 10.1038/s41467-024-51136-9. 2024