ESTUDIO CONTROLADO FRENTE A PLACEBO, ALEATORIZADO, DOBLE ENMASCARADO, DE EFICACIA DE GEVOKIZUMAB EN EL TRATAMIENTO DE PACIENTES CON UVEITIS POR ENFERMEDAD DE BEHÇET.

Datos básicos

Código:
CL3-78989-002
Protocolo:
CL3-78989-002
EUDRACT:
2012-001125-27
NCT:
Centro:
Dotación:
Año de incio:
Año de finalización:
2015
ENSAYO CLÍNICO

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INSTITUT RECHERCHES INTERNATIONALES SERVIER

Resultados del Ensayo Clínico


[Femtosecond laser-assisted superficial keratectomy as a treatment for bilateral band keratopathy].

García-Delpech S; (...); Díaz-Llopis M

Letter. 10.1016/j.oftal.2013.04.015. 2013


[Sensimed Triggerfish(®) as a new system for continuous recording of 24-hour intraocular pressure in glaucoma patients].

Hervás Ontiveros A; (...); Díaz-Llopis M

Letter. 10.1016/j.oftal.2012.12.013. 2013


A randomized multicenter study comparing seawater washes and carmellose artificial tears eyedrops in the treatment of dry eye syndrome

Diaz-Llopis, M; (...); Cisneros, A

Article. 10.2147/OPTH.S185409. 2019

  • Open Access.

Absceso orbitario tras anestesia peribulbar en mucocele frontoetmoidal.

Pardo-López D; (...); Diaz-Llopis M

Abstract of Published Item. 10.1016/j.oftal.2013.02.009. 2014


Adalimumab Therapy Optimization in Refractory Uveitis Due to Behcet's Disease after Achieving Remission. interventional Versus Control Group

Atienza-Mateo, B; (...); Blanco, R

Meeting Abstract. 2017


Ahmed valve, suture-less implantation: A new approach to an easier technique.

García-Delpech S; (...); Díaz-Llopis M

Article. 10.1097/IJG.0b013e318264ba4d. 2013


Altered antioxidant-oxidant status in the aqueous humor and peripheral blood of patients with retinitis pigmentosa.

Martínez-Fernández de la Cámara C; (...); Rodrigo R

Article. 10.1371/journal.pone.0074223. 2013

  • Open Access.

Altered antioxidant-oxidant status in the aqueous humor and peripheral blood of patients with retinitis pigmentosa.

Martínez-Fernández de la Cámara C; (...); Rodrigo R

Article. 2013

  • Open Access.

Alternative ultraviolet A lamp for corneal collagen crosslinking.

Diaz-Llopis M; (...); Garcia-Pous M

Article. 10.2147/OPTH.S33866. 2013

  • Open Access.

An unusual case of acoria in Sturge-Weber syndrome.

Rahhal-Ortuño M; (...); Rahhal MS

Editorial Material. 10.1177/1120672118804795. 2020


Analysis of factors that determine the diagnostic yield of temporal artery biopsy.

Suelves AM; (...); Díaz-Llopis M

Article. 10.1016/j.oftal.2012.06.027. 2013


Analysis of the Ush2a gene in medaka fish (Oryzias latipes).

Aller E; (...); Mullor JL

Article. 10.1371/journal.pone.0074995. 2013

  • Open Access.

Anterior chamber migration of dexametasone intravitreal implant (Ozurdex®).

Pardo-López D; (...); Díaz-Llopis M

Letter. 10.1007/s00417-011-1802-x. 2012


Anti-TNF-alpha therapy in patients with refractory uveitis due to Behcet's disease: a 1-year follow-up study of 124 patients

Calvo-Río V; (...); González-Gay MA

Article. 10.1093/rheumatology/keu266. 2014


AS-OCT of cyclitic membrane pre and post treatment with rtPA in the anterior chamber.

Paya, Emma Marin; (...); Llopis, Manuel Diaz

Case Reports. 10.22336/rjo.2022.37. 2022


Author's reply.

Díaz Llopis M

Letter. 10.1016/j.oftal.2018.10.007. 2019


Author's reply.

Díaz Llopis M

Letter. 10.1016/j.oftal.2018.11.001. 2019


Author's reply.

Díaz Llopis M

Letter. 10.1016/j.oftal.2019.01.001. 2019


CD4/CD8 ratio in aqueous humor in Uveitis.

Sanz-Marco E; (...); Diaz-Llopis M

Letter. 10.3109/09273948.2013.801993. 2013


Coexistent central retinal vein and artery occlusion in a patient with psoriasis receiving ustekinumab.

Rahhal-Ortuño M; (...); Roca-Ginés J

Article. 10.1016/j.oftal.2018.11.004. 2019


COMPARATIVE STUDY OF ADALIMUMAB, INFLIXIMAB AND CERTOLIZUMAB IN THE TREATMENT OF CYSTOID MACULAR EDEMA DUE TO BEHCET'S DISEASE

Martin-Varillas, J. L.; (...); Blanco, R.

Meeting Abstract. 10.1136/annrheumdis-2023-eular.4397. 2023


Comparative Study of Adalimumab, Infliximab and Certolizumab Pegol in the Treatment of Cystoid Macular Edema Due to Behcet's Disease

Barroso-Garcia, Nuria; (...); Blanco, Ricardo

Article. 10.3390/jcm13237388. 2024

  • Open Access.

COMPARATIVE STUDY OF INFLIXIMAB VERSUS ADALIMUMAB IN REFRACTORY UVEITIS ASSOCIATED TO CYSTOID MACULAR OEDEMADUE TO BEHCET'S DISEASE. MULCITENTER STUDY OF 40 CASES

Atienza-Mateo, B; (...); Blanco, R

Meeting Abstract. 10.1136/annrheumdis-2018-eular.3891. 2018

  • Open Access.

Comparative Study of Infliximab Versus Adalimumab in Refractory Uveitis Due to Behcet's Disease. National Multicenter Study of 177 Cases

Atienza-Mateo, B; (...); Blanco, R

Meeting Abstract. 2018


Comparative study of infliximab versus adalimumab in refractory uveitis due to Behet's disease, National multicenter study of 177 cases.

Atienza-Mateo B; (...); Blanco R

Article. 10.1002/art.41026. 2019

  • Open Access.

COMPARATIVE STUDY OF THE TREATMENT OF REFRACTORY CYSTOID MACULAR OEDEMA TO CONVENTIONAL IMMUNOSUPPRESSIVE THERAPY: TOCILIZUMAB VS ANTI-TNF. MULTICENTER STUDY OF 59 PATIENTS

Martin-Varillas, JL; (...); Blanco, R

Meeting Abstract. 10.1136/annrheumdis-2018-eular.3999. 2018

  • Open Access.

COMPARATIVE STUDY ON ANTI-TNF VS TOCILIZUMAB FOR TREATMENT OF REFRACTORY UVEITIC CYSTOID MACULAR EDEMA DUE TO BEHCET'S DISEASE. MULTICENTER STUDY OF 49 PATIENTS

Atienza-Mateo, B; (...); Blanco, R

Meeting Abstract. 10.1136/annrheumdis-2021-eular.307. 2021

  • Open Access.

Comparison of Treatment with Adalimumab, Infliximab and Certolizumab in Refractory Cystoid Macular Edema Due to Behcet Disease

Barroso-Garcia, Nuria; (...); Blanco, Ricardo

Meeting Abstract. 2023


Crystalline subtype of pre-descemetic corneal dystrophy.

Dolz-Marco R; (...); Díaz-Llopis M

Article. 2014


Do Nutritional Supplements Have a Role in Age Macular Degeneration Prevention?

Pinazo-Durán MD; (...); García-Layana A

Review. 10.1155/2014/901686. 2014

  • Open Access.

Enzymatic vitrectomy for diabetic retinopathy and diabetic macular edema.

Diaz-Llopis M; (...); Arevalo JF

Article. 10.4239/wjd.v4.i6.319. 2013


Eter etilico: un viejo aliado contra la blefaritis por Demodex resistente a ivermectina oral.

Hervas Ontiveros A; (...); Diaz-Llopis M

Letter. 10.1016/j.oftal.2013.06.004. 2014


Evaluation of the IL2/IL21, IL2RA and IL2RB genetic variants influence on the endogenous non-anterior uveitis genetic predisposition.

Cénit MC; (...); Martín J

Article. 10.1186/1471-2350-14-52. 2013


Focal Inferotemporal Scleral Bulge With Choroidal Thinning A New Observation on High-Penetration Optical Coherence Tomography

Dolz-Marco R; (...); Shields CL

Editorial Material. 10.1097/IAE.0000000000000294. 2015


High Dose Intravenous Methylprednisolone Induces Rapid Improvement in Severe Non-Infectious Uveitis. a Multicenter Study of 120 Patients

Vegas-Revenga, N; (...); Blanco, R

Meeting Abstract. 2018


HIGH DOSE INTRAVENOUS METHYLPREDNISOLONE INDUCES RAPID IMPROVEMENT IN SEVERE UVEITIS: A MULTICENTER STUDY OF 129 PATIENTS

Vegas-Revenga, N; (...); Blanco, R

Meeting Abstract. 10.1136/annrheumdis-2018-eular.3780. 2018

  • Open Access.

HIGH DOSE INTRAVENOUS METHYLPREDNISOLONE INDUCES RAPID IMPROVEMENT OF VISUAL ACUITY IN NON-INFECTIOUS UVEITIS OF DIFFERENT IMMUNE MEDIATED INFLAMMATORY DISEASES

Vegas-Revenga, N; (...); Blanco, R

Meeting Abstract. 10.1136/annrheumdis-2021-eular.2159. 2021

  • Open Access.

High Dose Intravenous Methylprednisolone Induces Rapid Improvement of Visual Acuity in Non-Infectious Uveitis of Different Immune Mediated Inflammatory Diseases

Vegas-Revenga, Nuria; (...); Blanco, Ricardo

Meeting Abstract. 2021


Hypersensitivity to Quail Egg Proteins: What About Hen Egg?

Micozzi, S; (...); Pastor-Varges, C

Editorial Material. 10.18176/jiaci.0076. 2016


Hypertensive choroidopathy and adrenal carcinoma: A new association.

Rahhal-Ortuño M; (...); Díaz-Llopis M

Article. 10.1016/j.oftal.2018.09.003. 2019


Intravenous methylprednisolone induces rapid improvement in non-infectious uveitis: a multicentre study of 112 patients

Vegas-Revenga, N.; (...); Blanco, R.

Article. 2022

  • Open Access.

Intravenous methylprednisolone induces rapid improvement in non-infectious uveitis: a multicentre study of 112 patients.

Vegas-Revenga N; (...); Blanco R

Article. 2021


INTRAVITREAL BEVACIZUMAB FOR CHOROIDAL NEOVASCULARIZATION IN AGE-RELATED MACULAR DEGENERATION 5-Year Results of The Pan-American Collaborative Retina Study Group

Arevalo JF; (...); Lujan S

Article. 10.1097/IAE.0000000000000827. 2016


Intravitreal bevacizumab plus grid laser photocoagulation or intravitreal bevacizumab or grid laser photocoagulation for diffuse diabetic macular edema: results of the Pan-american Collaborative Retina Study Group at 24 months.

Arevalo JF; (...); Berrocal MH

Article. 10.1097/IAE.0b013e3182695b83. 2013


INTRAVITREAL DEXAMETHASONE IMPLANT FOR THE TREATMENT OF REFRACTORY MACULAR EDEMA IN RETINAL VASCULAR DISEASES Results of the KKESH International Collaborative Retina Study Group

Alshahrani, ST; (...); KKESH Int Collaborative Retina Stu

Article. 10.1097/IAE.0000000000000616. 2016


Intravitreal Docosahexaenoic Acid in a Rabbit Model: Preclinical Safety Assessment

Dolz-Marco R; (...); Díaz-Llopis M

Article. 10.1371/journal.pone.0096872. 2014

  • Open Access.

Levels of thrombopoietin in aqueous humor of patients with noninfectious acute anterior uveitis.

Mondejar JJ; (...); Diaz-Llopis M

Article. 10.2147/OPTH.S56350. 2015

  • Open Access.

Local safety of repeated intravitreal Ozurdex

Hernández-Martínez P; (...); Díaz-Llopis M

Letter. 10.1038/eye.2013.265. 2014


MAINTENANCE TREATMENT WITH ADALIMUMAB IN REFRACTORY UVEITIS DUE TO BEHCET'S DISEASE: OPTIMISED VS NON-OPTIMISED GROUP

Martin-Varillas, JL; (...); Blanco, R

Meeting Abstract. 10.1136/annrheumdis-2018-eular.3963. 2018

  • Open Access.

Metabolomic changes in the rat retina after optic nerve crush.

Agudo-Barriuso M; (...); Mullor JL

Article. 10.1167/iovs.12-11451. 2013

  • Open Access.

Methotrexate as a treatment in ocular cicatricial moderate pemphigoid.

Hervás Ontiveros A; (...); Díaz-Llopis M

Article. 10.1016/j.oftal.2013.10.009. 2014


Myopia, the challenge of Ophthalmology and its worldwide "explosive epidemic".

Díaz Llopis M, Cisneros Lanuza A

Article. 10.1016/j.oftal.2018.05.009. 2018


Need to consensus for novel findings by optical coherence tomography in patients with age-related macular degeneration.

Gallego-Pinazo R; (...); Díaz-Llopis M

Letter. 10.1111/j.1755-3768.2012.02532.x. 2013


New insights into the genetic component of non-infectious uveitis through an Immunochip strategy

Marquez, A; (...); Martin, J

Article. 10.1136/jmedgenet-2016-104144. 2017

  • Open Access.

Non-contact wide-angled visualization with chandelier-assisted scleral buckling for primary uncomplicated rhegmatogenous retinal detachment

Roca, JA; (...); Wu, L

Article. 10.1007/s00417-020-04737-1. 2020


Noninfectious uveitis: strategies to optimize treatment compliance and adherence.

Dolz-Marco R; (...); Arévalo JF

Article. 10.2147/OPTH.S36650. 2015

  • Open Access.

Nuclear cataract as an early predictive factor for recalcitrant juvenile idiopathic arthritis-associated uveitis

Suelves, AM; (...); Christen, WG

Article. 10.1016/j.jaapos.2016.02.010. 2016


Optimization Protocol for Adalimumab Treatment in Refractory Uveitis Due to Behcet's Disease

Martin-Varillas, JL; (...); Blanco, R

Meeting Abstract. 2018


Oral propranolol and intravitreal ranibizumab for refractory serous macular detachment secondary to retinal capillary hemangioblastoma.

Hernández-Martínez P; (...); Cisneros Lanuza A

Letter. 10.1016/j.oftal.2014.01.007. 2015


Orbital involvement by non-Hodgkin lymphoma NK T cells.

Hervás-Ontiveros A; (...); Díaz-Llopis M

Article. 10.1016/j.oftal.2013.10.006. 2014


Outcomes of cataract surgery in diabetic patients: results of the Pan American Collaborative Retina Study Group

Gallego-Pinazo, R; (...); Pan-Amer Collaborative Retina Stud

Article. 10.5935/0004-2749.20140089. 2014

  • Open Access.

OUTCOMES OF TREATMENT OF PEDIATRIC CHOROIDAL NEOVASCULARIZATION WITH INTRAVITREAL ANTIANGIOGENIC AGENTS The Results of the KKESH International Collaborative Retina Study Group

Kozak I; (...); King Khaled Eye Specialist Hospital International Collaborative Retina Study Gro

Article. 10.1097/IAE.0000000000000200. 2014


Outer retinal tubulation analysis in cases of macular dystrophy.

Dolz-Marco R; (...); Díaz-Llopis M

Letter. 10.1016/j.oftal.2012.02.009. 2013


Oxidative stress and its downstream signaling in aging eyes

Pinazo-Durán MD; (...); Díaz-Llópis M

Review. 10.2147/CIA.S52662. 2014


Patients undergoing long-term treatment with antihypertensive eye drops responded positively with respect to their ocular surface disorder to oral supplementation with antioxidants and essential fatty acids.

Galbis-Estrada C; (...); Benítez-del-Castillo J

Article. 10.2147/CIA.S43191. 2013


Pattern dystrophy of the macula in a case of steinert disease.

Esteves F; (...); Gallego-Pinazo R

Article. 10.1159/000355385. 2013


Pharmacovitrectomy.

Dolz-Marco R; (...); Arévalo JF

Article. 10.1159/000360458. 2014


Pourfour du Petit syndrome associated with a cervical vertebral anomaly.

Marín-Lambíes C; (...); Díaz-Llopis M

Article. 10.1097/WNO.0b013e3182625212. 2012


Preoperative Bevacizumab for Tractional Retinal Detachment in Proliferative Diabetic Retinopathy: A Prospective Randomized Clinical Trial

Arevalo, JF; (...); Pan Amer Collaborative Retina

Article. 10.1016/j.ajo.2019.05.007. 2019

  • Open Access.

Rabdomiosarcoma alveolar orbitario enmascarado por sinusitis etmoidal en un adulto de 25 anos.

Sanz-Marco E; (...); Díaz-Llopis M

Abstract of Published Item. 10.1016/j.oftal.2012.10.012. 2014


Ranibizumab for serous macular detachment in branch retinal vein occlusions.

Gallego-Pinazo R; (...); Díaz-Llopis M

Article. 10.1007/s00417-012-2023-7. 2013


RAPID IMPROVEMENT IN CYSTOID MACULAR EDEMA WITH HIGH DOSE INTRAVENOUS METHYLPREDNISOLONE IN NON-INFECTIOUS UVEITIS OF DIFFERENT IMMUNE MEDIATED INFLAMMATORY DISEASES

Vegas-Revenga, N; (...); Blanco, R

Meeting Abstract. 10.1136/annrheumdis-2021-eular.3247. 2021

  • Open Access.

Rapid Improvement in Cystoid Macular Edema with High Dose Intravenous Methylprednisolone in Non-Infectious Uveitis of Different Immune Mediated Inflammatory Diseases

Vegas-Revenga, Nuria; (...); Blanco, Ricardo

Meeting Abstract. 2021


Re: Dexamethasone intravitreal implant for treatment of diabetic macular edema in vitrectomized patients.

Sanz-Marco E; (...); Diaz-Llopis M

Letter. 10.1097/IAE.0b013e31826187cb. 2012


Sequential multimodal imaging findings in a case of primary vitreoretinal lymphoma.

Dolz-Marco R; (...); Díaz-Llopis M

Article. 10.1097/ICB.0000000000000053. 2014


Smoking and age-related macular degeneration: review and update.

Velilla S; (...); Gallego-Pinazo R

Article. 10.1155/2013/895147. 2013

  • Open Access.

Specific association of IL17A genetic variants with panuveitis

Mucientes, A; (...); Martin, J

Article. 10.1136/bjophthalmol-2014-306106. 2015


Study of USH1 splicing variants through minigenes and transcript analysis from nasal epithelial cells.

Aparisi MJ; (...); Millán JM

Article. 10.1371/journal.pone.0057506. 2013

  • Open Access.

Successful Optimization of Adalimumab Therapy in Refractory Uveitis Due to Behcet's Disease

Martin-Varillas, JL; (...); Blanco, R

Article. 10.1016/j.ophtha.2018.02.020. 2018

  • Open Access.

Superdiluted atropine at 0.01% reduces progression in children and adolescents. A 5 year study of safety and effectiveness.

Diaz-Llopis M, Pinazo-Duran MD

Article. 10.1016/j.oftal.2017.12.015. 2018


Temporal artery biopsy.

Suelves AM, España Gregori E, Díaz-Llopis M

Letter. 10.1016/j.ophtha.2013.08.023. 2013


Topical linezolid for refractory bilateral Mycobacterium chelonae post-laser-assisted in situ keratomileusis keratitis.

Dolz-Marco R; (...); Díaz-Llopis M

Letter. 10.1001/archophthalmol.2012.1495. 2012


Treatment of Refractory Cystoid Macular Edema to Conventional Immunosuppressive Therapy: Tocilizumab Vs Anti-TNF-Alpha. Multicenter Study of 59 Patients

Martin-Varillas, JL; (...); Blanco, R

Meeting Abstract. 2018


Treatment of refractory dry eye associated with graft versus host disease with 0.03% tacrolimus eyedrops.

Sanz-Marco E; (...); Diaz-Llopis M

Article. 10.1089/jop.2012.0265. 2013


Treatment of refractory uveitis with adalimumab: a prospective multicenter study of 131 patients.

Díaz-Llopis M; (...); Arevalo JF

Article. 10.1016/j.ophtha.2012.02.018. 2012


Update on intravitreal anti-tumor necrosis factor alpha therapies for ocular disorders.

Pascual-Camps I; (...); Díaz-Llopis M

Article. 10.1186/s12348-014-0026-8. 2014


Update on the principles and novel local and systemic therapies for the treatment of non-infectious uveitis.

Gallego-Pinazo R; (...); Díaz-Llopis M

Article. 2013


Use of intravitreal rituximab and methotrexate in vitreoretinal lymphoma.

Rahhal-Ortuno, Miriam; (...); Diaz-Llopis, Manuel

Article. 10.1177/1120672120960589. 2020


Usefulness of adalimumab in the treatment of refractory uveitis associated with juvenile idiopathic arthritis.

García-De-Vicuña C; (...); Antón J

Article. 10.1155/2013/560632. 2013


Vogt-Koyanagi-Harada: treatment of recurrence after administration of 3 intravenous bolus of 1?g of corticosteroids and mycophenolate mofetil.

Aguilar-González M; (...); Andreu-Fenoll M

Case Reports. 10.1016/j.oftale.2020.06.027. 2021


Vogt-Koyanagi-Harada: treatment of recurrence after administration of 3 intravenous bolus of 1g of corticosteroids and mycophenolate mofetil.

Aguilar-González M; (...); Andreu-Fenoll M

Article. 10.1016/j.oftal.2020.06.033. 2021


Xantogranuloma necrobiotico. Diagnostico diferencial, tratamiento e implicaciones sistemicas. A proposito de un caso.

Sanz-Marco E; (...); Diaz-Llopis M

Abstract of Published Item. 10.1016/j.oftal.2012.11.007. 2014


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