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  3. Methotrexate as a treatment in ocular cicatricial moderate pemphigoid.

Methotrexate as a treatment in ocular cicatricial moderate pemphigoid.

Fecha de publicación:

Autores de IIS La Fe

Participantes ajenos a IIS La Fe

  • Jiménez Herrero E

Grupos

Abstract

CLINICAL CASE: A 73 year-old woman presented with a history of non-specific symptoms and photophobia in both eyes of 1 year progression. The examination revealed a bilateral symblepharon and fornix shortening. Immunohistochemical analysis confirmed the presence of linear deposits of IgG, IgM and C3 along the conjunctival basement membrane. With the diagnosis of Ocular Cicatricial Pemphigoid, systemic treatment with subcutaneous methotrexate was prescribed. DISCUSSION: We consider such treatment a very effective initial immunosuppressive alternative in patients with moderate conjunctival inflammation and in cases of rapid progression.

Datos de la publicación

ISSN/ISSNe:
0365-6691, 1989-7286

Archivos de la Sociedad Espanola de Oftalmologia  Elsevier Ltd

Tipo:
Article
Páginas:
447-449
PubMed:
24359845
Factor de Impacto:
0,230 SCImago ℠
Cuartil:
Q3 SCImago ℠

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Keywords

  • Agentes inmunosupresores; Complicaciones cicatriz; Complications scar; Diagnosis ocular cicatricial pemphigoid; Diagnostico penfigoide ocular cicatricial; Etiology; Etiologia; Immunosuppressive agents; Methotrexate; Metotrexate; Ocular cicatricial pemphigoid; Penfigoide ocular cicatricial; Therapeutic use; Uso terapeutico

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