Vogt-Koyanagi-Harada: treatment of recurrence after administration of 3 intravenous bolus of 1?g of corticosteroids and mycophenolate mofetil.

Autores de IIS La Fe

• Marina Aguilar González

  Autor

• Paula Martinez Lopez Corell

  Autor

• Emma Marin Paya

  Autor

• Manuel Díaz Llopis

  Autor

• María Andreu Fenoll

  Autor

Participantes ajenos a IIS La Fe

• Gallego-Pinazo R

Grupos

• Biomedicina Molecular, Celular y Genómica

  

  Leader

  José María Millán Salvador

Abstract

The case is presented on a young Honduran female with no medical history of note, who presented with multiple areas of exudative retinal detachment (RD), and a best-corrected visual acuity of 1.3 logMAR in both eyes. She was diagnosed with incomplete Vogt-Koyanagi-Harada syndrome, and treated early with a combination of intravenous therapy with 1?g of prednisolone per day for 3 days, as recommended by published evidence, as well as mycophenolate mofetil (2?g per day). During the corticosteroids tapering, there was a recurrence of exudative retinal detachments, and megadoses of 1?g of intravenous corticosteroids per day were reintroduced for 6 days until the complete resolution of the fluid of the exudative RD, and cyclosporine (100?mg per day), subtenon triamcinolone (40?mg/mL), and intravitreal ranibizumab once a month in the both eyes were added to the treatment, with a great control of choroidal inflammation that resulted in the remission of symptoms and signs.

Keywords

• Medical treatment, Recurrence, Recurrencia, Tratamiento médico, Vogt-Koyanagi-Harada