Multiparametric evaluation of the cytoprotective effect of the Mangifera indica L. stem bark extract and mangiferin in HepG2 cells.

Autores de IIS La Fe

• Laia Tolosa Pardo

  Autor

• Idania Rodeiro Guerra

  Autor

• María Teresa Donato Martín

  Autor

• José Vicente Castell Ripoll

  Autor

• María José Gómez-Lechón Moliner

  Autor

Participantes ajenos a IIS La Fe

• Herrera JA
• Delgado R

Grupos

• Hepatología experimental y Trasplante hepático

• Unidad Mixta de Investigación en Hepatología Experimental

Abstract

Mango (Mangifera indica L.) stem bark extract (MSBE) is a natural product with biological properties and mangiferin is the major component. This paper reported the evaluation of the protective effects of MSBE and mangiferin against the toxicity induced in HepG2 cells by tert-butyl hydroperoxide or amiodarone.