Portal de investigación
- Inicio
- Proyectos y Estudios
- ENSAYO ABIERTO DE FASE III PARA EVALUAR LA SEGURIDAD,TOLERABILIDAD E INMUNOGENIA DE LA VACUNA ANTINEUMOCOCICA CONJUGADA TRIDECAVALENTE SEGUIDA DE LA VACUNA ANTINEUMOCOCICA POLISACARIDA DE 23 SEROTIPOS EN RECEPTORES DE TRASPLANTE ALOGENICO DE CELULAS GERMI NALES HEMATOPOYETICAS DE 2 O MAS AÑOS DE EDAD.
ENSAYO ABIERTO DE FASE III PARA EVALUAR LA SEGURIDAD,TOLERABILIDAD E INMUNOGENIA DE LA VACUNA ANTINEUMOCOCICA CONJUGADA TRIDECAVALENTE SEGUIDA DE LA VACUNA ANTINEUMOCOCICA POLISACARIDA DE 23 SEROTIPOS EN RECEPTORES DE TRASPLANTE ALOGENICO DE CELULAS GERMI NALES HEMATOPOYETICAS DE 2 O MAS AÑOS DE EDAD.
Datos básicos
- Protocolo:
- 6115A1-3003-WW
- EUDRACT:
- 2009-012087-13
- NCT:
- Centro:
- HOSPITAL UNIVERSITARI I POLITÈCNIC LA FE
- Año de incio:
- 2010
- Año de finalización:
- 2013
Objetivos del proyecto
Observaciones: Estado Comité: FINALIZADO
Documentos
- No hay documentos
Participantes
Grupos
Financiadores - Promotores
Resultados del Ensayo Clínico
[Guidelines for diagnosis, treatment and monitoring of primary immune thrombocytopenia].
Sanz MÁ; (...); Sociedad Española de Hematología y Oncología Pediátricas
Abstract of Published Item. 10.1016/j.medcli.2011.11.011. 2012
A novel approach to the evaluation of bleeding-related episodes in patients with chronic immune thrombocytopenia.
Weitz I; (...); Deuson R
Article. 10.1185/03007995.2012.684046. 2012
A novel NUP98/RARG gene fusion in acute myeloid leukemia resembling acute promyelocytic leukemia.
Article. 10.1182/blood-2010-06-291658. 2011
A scoring system to predict the risk of death during induction with anthracycline plus cytarabine-based chemotherapy in patients with de novo acute myeloid leukemia.
Valcárcel D; (...); CETLAM Group
Article. 10.1002/cncr.26273. 2012
Aberrant methylation of tumor suppressor genes in patients with refractory anemia with ring sideroblasts
Valencia, Ana; (...); Sanz, Guillermo F.
Article. 10.1016/j.leukres.2010.08.012. 2011
Absence of mutations in the activation loop and juxtamembrane domains of VEGFR-1 and VEGFR-2 gene in chronic myelomonocytic leukemia (CMML).
Letter. 10.1016/j.leukres.2011.10.029. 2012
Additional chromosome abnormalities in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and chemotherapy
Cervera, Jose; (...); Sanz, Miguel A.
Article. 10.3324/haematol.2009.013243. 2010
Analysis of ASXL1, IDH1, IDH2, c-CBL, and WT1 Mutations in De Novo Acute Myeloid Leukaemia
Ibanez, Mariam; (...); Sanz, Miguel A.
Article. 2011
Analysis of EQ-5D scores from two phase 3 clinical trials of romiplostim in the treatment of immune thrombocytopenia (ITP).
Sanz MA; (...); Isitt JJ
Article. 10.1016/j.jval.2010.10.017. 2011
Analysis of mutational status, SNP rs16754, and expression levels of Wilms tumor 1 (WT1) gene in acute promyelocytic leukemia.
Gaur GC; (...); Lo-Coco F
Article. 10.1007/s00277-012-1546-7. 2012
Analysis of SNP rs16754 of WT1 gene in a series of de novo acute myeloid leukemia patients.
Article. 10.1007/s00277-012-1596-x. 2012
Antifungal prophylaxis in the haematological patient: a practical approach.
Vázquez L; (...); Barberán J
Article. 2012
ANTIFUNGAL SUSCEPTIBILITY OF CANDIDA PARAPSILOSIS AND CANDIDA ALBICANS BLOODSTREAM ISOLATES TO AMPHOTERICIN B DETERMINED BY FLOW CYTOMETRY METHODOLOGY
Cordon, Lourdes; (...); Peman, Javier
Article. 2010
BRAF V600E mutation in adult acute lymphoblastic leukemia.
Alonso CM; (...); Sanz Alonso MA
Letter. 10.3109/10428194.2012.733878. 2013
Caspofungin for the treatment of invasive fungal disease in hematological patients (ProCAS Study).
Jarque I; (...); Spanish Pethema Group
Article. 10.3109/13693786.2012.693213. 2013
Central nervous system involvement at first relapse in patients with acute myeloid leukemia.
Martínez-Cuadrón D; (...); Sanz MA
Article. 10.3324/haematol.2011.042960. 2011
Clinical significance of CD56 expression in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline-based regimens
Montesinos, Pau; (...); Sanz, Miguel A.
Article. 10.1182/blood-2010-04-277434. 2011
Cost-effectiveness of posaconazole versus fluconazole or itraconazole in the prevention of invasive fungal infections among high-risk neutropenic patients in Spain.
Grau S; (...); Sanz MA
Article. 10.1186/1471-2334-12-83. 2012
Cross-sectional validation study of patient-reported outcomes in patients with paroxysmal nocturnal haemoglobinuria.
Weitz I; (...); Hill A
Article. 10.1111/j.1445-5994.2012.02924.x. 2013
CYP2C8 gene polymorphism and bisphosphonate-related osteonecrosis of the jaw in patients with multiple myeloma.
Such E; (...); de la Rubia J
Article. 10.3324/haematol.2011.042572. 2011
Does microgranular variant morphology of acute promyelocytic leukemia independently predict a less favorable outcome compared with classical M3 APL? A joint study of the North American Intergroup and the PETHEMA Group
Tallman, Martin S.; (...); Sanz, Miguel A.
Article. 10.1182/blood-2010-06-288613. 2010
Efficacy and safety of rituximab in adult patients with idiopathic relapsing or refractory thrombotic thrombocytopenic purpura: Results of a Spanish multicenter study
de la Rubia, Javier; (...); Sanz, Miguel A.
Article. 10.1016/j.transci.2010.09.018. 2010
Fragment length analysis screening for detection of CEBPA mutations in intermediate-risk karyotype acute myeloid leukemia.
Article. 10.1007/s00277-011-1234-z. 2012
Guidelines for the Treatment of Invasive Fungal Disease by Aspergillus spp. and Other Fungi Issued by the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC). 2011 Update
Fortun, Jesus; (...); Cuenca-Estrella, Manuel
Article. 10.1016/j.eimc.2011.01.010. 2011
Helicobacter pylori in the diagnosis, treatment and follow-up of primary immune thrombocytopenia in Spain Reply
Jarque, Isidro, Sanz, Miguel A.
Article. 10.1016/j.medcli.2012.11.002. 2013
Impact of adjunct cytogenetic abnormalities for prognostic stratification in patients with myelodysplastic syndrome and deletion 5q
Mallo, M.; (...); Sole, F.
Article. 10.1038/leu.2010.231. 2011
Improving acute promyelocytic leukemia (APL) outcome in developing countries through networking, results of the International Consortium on APL.
Rego EM; (...); Sanz MA
Article. 10.1182/blood-2012-08-449918. 2013
Intravenous busulfan and melphalan as a conditioning regimen for autologous stem cell transplantation in patients with newly diagnosed multiple myeloma: a matched comparison to a melphalan-only approach.
Blanes M; (...); de la Rubia J
Article. 10.1016/j.bbmt.2012.08.009. 2013
Long-term management of chronic immune thrombocytopenic purpura in adults.
Palau, Javier, Jarque, Isidro, Sanz, Miguel A
Article. 10.2147/IJGM.S4722. 2010
Modern Approaches to Treating Acute Promyelocytic Leukemia
Sanz, Miguel A., Lo-Coco, Francesco
Review. 10.1200/JCO.2010.32.1067. 2011
New autoimmune diseases after cord blood transplantation: a retrospective study of EUROCORD and the Autoimmune Disease Working Party of the European Group for Blood and Marrow Transplantation.
Daikeler T; (...); Rocha V
Article. 10.1182/blood-2012-07-445965. 2013
Open issues on bleeding and thrombosis in acute promyelocytic leukemia
Sanz, Miguel A., Montesinos, Pau
Article. 10.1016/S0049-3848(10)70013-X. 2010
Outcome of Antifungal Combination Therapy for Invasive Mold Infections in Hematological Patients is Independent of the Chosen Combination.
Rojas R; (...); Torres A
Article. 10.4084/MJHID.2012.011. 2012
Outcomes and prognostic factors of adults with acute lymphoblastic leukemia who relapse after allogeneic hematopoietic cell transplantation. An analysis on behalf of the Acute Leukemia Working Party of EBMT.
Spyridonidis A; (...); Immunotherapy Subcommittee of Acute Leukemia Working Party
Article. 10.1038/leu.2011.351. 2012
Presenting features and treatment outcome of acute promyelocytic leukemia arising after multiple sclerosis
Ammatuna, Emanuele; (...); Lo-Coco, Francesco
Article. 10.3324/haematol.2010.036657. 2011
Prognostic value of cytogenetics in adult patients with Philadelphia-negative acute lymphoblastic leukemia.
Gómez-Seguí I; (...); Sanz MA
Article. 10.1007/s00277-011-1331-z. 2012
Prognostic value of FLT3 mutations in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline monochemotherapy
Barragan, Eva; (...); Sanz, Miguel A.
Article. 10.3324/haematol.2011.044933. 2011
Quantitative Expression Analysis of WT1 Main Isoforms in AML
Luna, Irene; (...); Sanz, Miguel A.
Article. 2011
Rapid screening of ASXL1, IDH1, IDH2, and c-CBL mutations in de novo acute myeloid leukemia by high-resolution melting.
Ibáñez M; (...); Sanz MA
Article. 10.1016/j.jmoldx.2012.06.006. 2012
Recommendations for the treatment of invasive fungal infection caused by filamentous fungi in the hematological patient
Barberan, Jose; (...); de la Torre Cisneros, Julian
Article. 2011
Reduced corticosteroid use in adult patients with primary immune thrombocytopenia receiving romiplostim
Michel, Marc; (...); Kreuzbauer, Georg
Article. 10.1179/102453311X13025568942005. 2011
Results from a randomized trial of salvage chemotherapy followed by lestaurtinib for patients with FLT3 mutant AML in first relapse
Levis, Mark; (...); Smith, B. Douglas
Article. 10.1182/blood-2010-08-301796. 2011
Risk-Adapted Treatment for Low- and Intermediate-Risk Acute Promyelocytic Leukemia
Sanz, Miguel A., Montesinos, Pau
Article. 10.3816/CLML.2010.s.025. 2010
Risk-adapted treatment of acute promyelocytic leukemia based on all-trans retinoic acid and anthracycline with addition of cytarabine in consolidation therapy for high-risk patients: further improvements in treatment outcome
Sanz, Miguel A.; (...); Lowenberg, Bob
Article. 10.1182/blood-2010-01-266007. 2010
Rozrolimupab, a mixture of 25 recombinant human monoclonal RhD antibodies, in the treatment of primary immune thrombocytopenia.
Robak T; (...); Petersen J
Article. 10.1182/blood-2012-06-438804. 2012
Screening for IDH mutations in chronic myelomonocytic leukemia.
Ibañez M; (...); Sanz MA
Letter. 10.3109/10428194.2012.701295. 2013
Significance of increased blastic-appearing cells in bone marrow following myeloablative unrelated cord blood transplantation in adult patients.
Montesinos P; (...); Sanz GF
Article. 10.1016/j.bbmt.2011.11.008. 2012
SIGNIFICANCE OF INCREASED BONE MARROW BLASTS AFTER MYELOID ENGRAFTMENT IN ADULT PATIENTS UNDERGOING UNRELATED CORD BLOOD TRANSPLANTATION
Gascon, A.; (...); Sanz, M.
Article. 2010
Single-unit umbilical cord blood transplantation from unrelated donors in patients with hematological malignancy using busulfan, thiotepa, fludarabine and ATG as myeloablative conditioning regimen.
Sanz J; (...); Grupo Español de Trasplante Hematopoyético y Terapia Celular (GETH)
Article. 10.1038/bmt.2012.13. 2012
Susceptibility to amphotericin B and fluconazole determined by flow cytometry. Is it the same?
Cordon, L.; (...); Sanz, M.
Article. 2011
The differentiation syndrome in patients with acute promyelocytic leukemia: experience of the pethema group and review of the literature.
Montesinos, Pau, Sanz, Miguel A
Article. 10.4084/MJHID.2011.059. 2011
The European LeukemiaNet: achievements and perspectives
Hehlmann, Ruediger; (...); Saussele, Susanne
Article. 10.3324/haematol.2010.032979. 2011
The impact of medical education and networking on the outcome of leukemia treatment in developing countries. The experience of International Consortium on Acute Promyelocytic Leukemia (IC-APL).
Rego EM; (...); Sanz MA
Article. 10.1179/102453312X13336169155376. 2012
Therapy-Related Myeloid Neoplasms in Patients With Acute Promyelocytic Leukemia Treated With All-Trans-Retinoic Acid and Anthracycline-Based Chemotherapy
Montesinos, Pau; (...); Sanz, Miguel
Article. 10.1200/JCO.2010.29.2268. 2010
Treatment of invasive fungal infections in high risk hematological patients. The outcome with liposomal amphotericin B is not negatively affected by prior administration of mold-active azoles.
De la Serna J; (...); Vallejo C
Article. 2013
Treatment of multiple myeloma in the elderly: realities and hopes
De La Rubia, Javier, Sanz, Miguel A.
Review. 10.3109/10428194.2010.530361. 2011
Umbilical cord blood transplantation from unrelated donors in adult patients with chronic myeloid leukaemia
Sanz, Jaime, Sanz, Guillermo F.
Article. 10.1016/j.beha.2010.05.001. 2010
Unrelated Transplantation for Poor-Prognosis Adult Acute Lymphoblastic Leukemia: Long-Term Outcome Analysis and Study of the Impact of Hematopoietic Graft Source
Ferra, Christelle; (...); Ribera, Josep-Maria
Article. 10.1016/j.bbmt.2010.02.003. 2010