Management of cytomegalovirus in adult solid organ transplant patients: GESITRA-IC-SEIMC, CIBERINFEC, and SET recommendations update.

Autores de IIS La Fe

• Victoria Aguilera Sancho-Tello

  Autor

• 

  Marina Berenguer Haym

  Autor

Participantes ajenos a IIS La Fe

• Ruiz-Arabi, Elisa
• Torre-Cisneros, Julian
• Alonso, Rodrigo
• Bestard, Oriol
• Bodro, Marta
• Cantisan, Sara
• Carratala, Jordi
• Caston, Juan Jose
• Cordero, Elisa
• Facundo, Carme
• Farinas, Maria Carmen
• Fernandez-Alonso, Mirian
• Fernandez-Ruiz, Mario
• Fortun, Jesus
• Garcia-Cosio, Maria Dolores
• Herrera, Sabina
• Iturbe-Fernandez, David
• Len, Oscar
• Lopez-Medrano, Francisco
• Lopez-Oliva, Maria Ovidia
• Los-Arcos, Ibai
• Marcos, Maria Angeles
• Martin-Davila, Pilar
• Monforte, Victor
• Munoz, Patricia
• Navarro, David
• Paez-Vega, Aurora
• Perez, Ana Belen
• Redondo, Natalia
• Alvarez, Regino Rodriguez
• Rodriguez-Benot, Alberto
• Rodriguez-Goncer, Isabel
• San-Juan, Rafael
• Sanchez-Cespedes, Javier
• Valerio, Maricela
• Vaquero, Jose Manuel
• Viasus, Diego
• Vidal, Elisa
• Aguado, Jose Maria

Grupos

• Hepatología, Cirugia Hepatobiliopancreática y Trasplantes

Abstract

Cytomegalovirus (CMV) infection remains a significant challenge in solid organ transplantation (SOT). The last international consensus guidelines on the management of CMV in SOT were published in 2018, highlighting the need for revision to incorporate recent advances, notably in cell-mediated immunity monitoring, which could alter the current standard of care. A working group including members from the Group for the Study of Infection in Transplantation and the Immunocompromised Host (GESITRA-IC) of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) and the Spanish Society of Transplantation (SET), developed consensus-based recommendations for managing CMV infection in SOT recipients. Recommendations were classified based on evidence strength and quality using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system. The final recommendations were endorsed through a consensus meeting and approved by the expert panel.

Copyright © 2024 The Authors. Published by Elsevier Inc. All rights reserved.

Keywords

• Cytomegalovirus; Expert; Infection; Prevention; Recommendations; SOT; Transplantation