Portal de investigación
- Inicio
- Proyectos y Estudios
- ESTUDIO DE FASE 3, ALEATORIZADO, DOBLE CIEGO, CONTROLADO CON PLACEBO, DE GRUPOS PARALELOS PARA EVALUAR LA EFICACIA Y LA SEGURIDAD DE LUMACAFTOR EN COMBINACIÓN CON IVACAFTOR EN PACIENTES DE 12 O MÁS AÑOS DE EDAD CON FIBROSIS QUÍSTICA Y HOMOCIGÓTICOS PARA LA MUTACIÓN F508DEL-CFTR.
ESTUDIO DE FASE 3, ALEATORIZADO, DOBLE CIEGO, CONTROLADO CON PLACEBO, DE GRUPOS PARALELOS PARA EVALUAR LA EFICACIA Y LA SEGURIDAD DE LUMACAFTOR EN COMBINACIÓN CON IVACAFTOR EN PACIENTES DE 12 O MÁS AÑOS DE EDAD CON FIBROSIS QUÍSTICA Y HOMOCIGÓTICOS PARA LA MUTACIÓN F508DEL-CFTR.
Datos básicos
- Protocolo:
- VX12-809-104
- EUDRACT:
- 2012-003990-24
- NCT:
- Centro:
- HOSPITAL UNIVERSITARI I POLITÈCNIC LA FE
- Año de incio:
- 2013
- Año de finalización:
- 2014
Documentos
- No hay documentos
Participantes
Financiadores - Promotores
Resultados del Ensayo Clínico
[Disseminated non-tuberculous mycobacterial infection in a patient with hyper-IgE syndrome].
Romero Rubio MT; (...); Santos Serrano L
Letter. 10.1016/j.anpedi.2013.01.017. 2013
Diagnostic power of echocardiographic speckle tracking of the tricuspid annular motion to assess right ventricular dysfunction
Alonso P; (...); Salvador A
Letter. 10.1016/j.ijcard.2013.12.157. 2014
Does the calcineurin inhibitor have influence on cytomegalovirus infection in heart transplantation?
Rodríguez-Serrano M; (...); Salvador-Sanz A
Article. 10.1111/ctr.12282. 2014
Does the Calcineurin Inhibitor Have Influence on Cytomegalovirus Infection in Heart Transplantation?
Sanchez-Lazaro, I.; (...); Salvador-Sanz, A.
Article. 10.1016/j.healun.2014.01.067. 2014
EFFECT OF CYP3A5 GENOTYPE ON TACROLIMUS DOSE REQUIREMENT, NEPHROTOXICITY AND ACUTE REJECTION IN KIDNEY TRANSPLANTATION: A SYSTEMATIC REVIEW AND META-ANALYSIS OF OBSERVATIONAL STUDIES
Rojas, L.; (...); Alino, S. F.
Article. 2013
EFFECTS OF POLYMORPHIMS OF CYP3A5 AND ABCB1 GENES ON CHRONIC NEPHROPATHY: COHORT STUDY
Rojas, L.; (...); Alino, S. F.
Article. 2013
Epidemiology, diagnosis and treatment of fungal respiratory infections in the critically ill patient.
Garnacho-Montero J; (...); Barberán J
Article. 2013
Estudio de utilizacion de boceprevir y telaprevir para el tratamiento de la hepatitis C cronica.
Marrero-Álvarez P; (...); Poveda-Andrés JL
Abstract of Published Item. 10.7399/FH.2014.38.1.1128. 2014
Evaluation of humoral immunity profiles to identify heart recipients at risk for development of severe infections: A multicenter prospective study
Sarmiento, E; (...); Carbone, J
Article. 10.1016/j.healun.2016.10.004. 2017
Evaluation of omalizumab prescription for asthma patients. Adequacy to the recommendations of the regulatory agencies and asthma guidelines
de Rojas, H. F.; (...); Nieto Garcia, A.
Meeting Abstract. 2013
Genotype and Allele Frequencies of Drug-Metabolizing Enzymes and Drug Transporter Genes Affecting Immunosuppressants in the Spanish White Population
Bosó V; (...); Aliño SF
Article. 10.1097/FTD.0b013e3182a94e65. 2014
Heart transplantation and metabolic syndrome: which calcineurin inhibitor most promotes its development?
Martinez-Dolz, L.; (...); Salvador-Sanz, A.
Article. 2013
High-permeability region size on perfusion CT predicts hemorrhagic transformation after intravenous thrombolysis in stroke
Puig, J; (...); Castellanos, M
Article. 10.1371/journal.pone.0188238. 2017
Hyperkalemia in heart failure patients: current challenges and future prospects
Lopez-Vilella, R; (...); Almenar-Bonet, L
Review. 10.2147/RRCC.S75680. 2016
Impact of basal heart rate on long-term prognosis of heart transplant patients.
Melero-Ferrer JL; (...); Salvador-Sanz A
Article. 10.1111/tri.12082. 2013
Intravenous sildenafil in right ventricular dysfunction with pulmonary hypertension following a heart transplant.
Bonet LA; (...); Sanz AS
Article. 10.5301/HEART.2014.12492. 2014
Meta-analysis and systematic review of the effect of the donor and recipient CYP3A5 6986A>G genotype on tacrolimus dose requirements in liver transplantation.
Rojas LE; (...); Aliño SF
Article. 10.1097/FPC.0b013e3283642fb3. 2013
Metabolic syndrome in heart transplantation: impact on survival and renal function.
Martínez-Dolz L; (...); Montero JA
Article. 10.1111/tri.12149. 2013
Practical guidelines: lung transplantation in patients with cystic fibrosis.
Hirche TO; (...); ECORN-CF Study Group
Article. 10.1155/2014/621342. 2014
Selective ophthalmic intra-arterial melphalan therapy for advanced retinoblastoma: implementation and outcomes of a new chemotherapy protocol.
Valero García S; (...); Poveda Andrés JL
Article. 10.1177/1078155212457964. 2013
Single Nucleotide Polymorphisms, SNPs, Associated With the Efficacy and Security of Immunosuppressive Treatment in Heart Transplantation
Sanchez-Lazaro, I.; (...); Salvador-Sanz, A.
Article. 10.1016/j.healun.2014.01.392. 2014
SNPs and taxane toxicity in breast cancer patients
Bosó V; (...); Aliño SF
Article. 10.2217/PGS.14.127. 2014
Spanish Heart Transplant Registry. 29th Official Report of the Spanish Society of Cardiology Working Group on Heart Failure
Gonzalez-Vilchez, F; (...); Representation Equipos Espanoles T
Article. 10.1016/j.recesp.2018.07.020. 2018
Spanish Heart Transplant Registry. 30th Official Report of the Spanish Society of Cardiology Working Group on Heart Failure (1984-2018)
Gonzalez-Vilchez, F; (...); Abella-Anton, R
Article. 10.1016/j.rec.2019.09.005. 2019
Spanish Heart Transplant Registry. 31th Official Report of the Heart Failure Association of the Spanish Society of Cardiology.
González-Vilchez F; (...); Groba Marco MDV
Article. 10.1016/j.rec.2020.06.035. 2020
Tolvaptan in hyponatremic patients with heart failure: initial experience
Martinez-Dolz, L.; (...); Salvador-Sanz, A.
Article. 2013
Trasplante pulmonar en la linfangioleiomiomatosis esporádica. Estudio de 7 casos.
Ansótegui Barrera E; (...); Padilla Alarcón J
Abstract of Published Item. 10.1016/j.medcli.2013.05.036. 2013
Treatment adherence and other patient-reported outcomes as cost determinants in multiple sclerosis: a review of the literature
Lizan, L; (...); Polanco, C
Review. 10.2147/PPA.S67253. 2014