Haplotypes of the endothelial protein C receptor gene and Behçet's disease.

Autores de IIS La Fe

• Silvia Navarro Rosales

  Autor

• Elena Bonet Estruch

  Autor

• 

  Pilar Medina Badenes

  Autor

• Laura Martos Marin

  Autor

• Jose Maria Ricart Vaya

  Autor

• Amparo Vaya Montañana

  Autor

• José Antonio Todolí Parra

  Autor

• Amparo Estelles Cortes

  Autor

• Francisco España Furio

  Autor

Participantes ajenos a IIS La Fe

• Fontcuberta J

Grupos

• Hemostasia, Trombosis, Arteriosclerosis y Biología vascular

Abstract

Behçet's disease is a vasculitis of unknown cause in which thrombosis occurs in about 25% of patients. Two haplotypes of the endothelial protein C receptor gene, H1 and H3, are associated with the risk of thrombosis. Thus, the objective of this study was to evaluate the influence of these haplotypes on the thrombosis risk in Behçet's disease.