Portal de investigación
CHARACTERIZACION OF MICRO RNA MODULATION OF PROTEIN EXPRESSION IN SUDDEN CARDIAC DEATH
Datos básicos
- Protocolo:
- CP09/00065 (MIGUEL SERVET)
- EUDRACT:
- NCT:
- Centro:
- Año de incio:
- 2010
- Año de finalización:
- 2016
Objetivos del proyecto
FAVORABLE
Documentos
- No hay documentos
Participantes
-
Pilar Medina Badenes
Doctor
Grupos
-
Hemostasia, Trombosis, Arteriosclerosis y Biología vascular
Investigador Principal
Pilar Medina Badenes
Financiadores - Promotores
Resultados del Ensayo Clínico
Current knowledge of genetic risk factors for venous thrombosis
SILVIA NAVARRO ROSALES; (...); PILAR MEDINA BADENES
Capítulo de un Libro. 2014
349 - Clinical usefulness of eight novel monoclonal antibodies against prostate-specific antigen (PSA) to differentiate prostate cancer and benign prostate hyperplasia. Measurement of different PSA molecular forms with specific immunoassays
S. Navarro; (...); P. Medina-Badenes
Article. 10.1016/S1569-9056(17)30413-X. 2017
A MODIFICATION OF CALIBRATED AUTOMATED THROMBIN GENERATION ASSAY TO EXPLORE NEW COFACTORS OF ACTIVATED PROTEIN C IN PLASMA
Martos, L.; (...); Navarro Rosales, S.
Meeting Abstract. 10.1016/S0049-3848(14)50233-2. 2014
A NOVEL TISSUE MICRORNA SIGNATURE FOR ARRHYTHMOGENIC CARDIOMYOPATHY
Zorio, E.; (...); Medina, P.
Article. 10.1016/S0049-3848(14)50269-1. 2014
A novel tissue microRNA signature for arrythmogenic cardiomyopathy.
Zorio, E; (...); Medina, P.
Article. 2014
A predictive model for prostate cancer incorporating PSA molecular forms and age.
Oto J; (...); Navarro S
Article. 10.1038/s41598-020-58836-4. 2020
A simplified assay for quantification of circulating activated protein C levels
Medina, P.; (...); Espana, F.
Article. 2013
A simplified assay for quantification of circulating activated protein C levels
Bonet, Elena; (...); Espana, Francisco
Article. 10.1016/j.thromres.2012.08.025. 2012
A simplified assay for the quantification of circulating activated protein C
Martos L; (...); Medina P
Article. 10.1016/j.cca.2016.05.025. 2016
a2-Macroglobulin is a significant in vivo inhibitor of activated protein C and low levels of APC:a2M are associated with venous thromboembolism
Navarro S; (...); Medina P
Article. 2018
Activated protein C assays: a review.
Review. 10.1016/j.cca.2019.11.005. 2020
Advances in the genetics of haemostatic monogenic diseases
España, Francisco; (...); Estellés, Amparo
Article. 2011
alpha(2)-Macroglobulin Is a Significant In Vivo Inhibitor of Activated Protein C and Low APC: alpha M-2 Levels Are Associated with Venous Thromboembolism
Martos, L; (...); Medina, P
Article. 10.1055/s-0038-1629902. 2018
Assessment of the thrombin generation assay in haemophilia: comparative study between fresh and frozen platelet-rich plasma.
Vila V; (...); España F
Article. 10.1111/hae.12044. 2013
Association of haplotypes (H) 1 and 3 of the endothelial protein c receptor gene (PROCR) with venous thromboembolism
Bonet, Elena; (...); Espana, Francisco
Article. 10.1016/j.thromres.2012.08.027. 2012
Association of haplotypes (H) 1 and 3 of the endothelial protein C receptor gene (PROCR) with venous thromboembolism
Navarro, S.; (...); Medina, P.
Article. 2013
Association of the thrombomodulin gene c.1418C>T polymorphism with thrombomodulin levels and with venous thrombosis risk.
Navarro S; (...); España F
Article. 10.1161/ATVBAHA.113.301360. 2013
Circulating Cell-Free DNA in Liquid Biopsies as Potential Biomarker for Bladder Cancer: A Systematic Review
Herranz, R; (...); Medina, P
Review. 10.3390/cancers13061448. 2021
COMBINED DEFICIENCY OF PROTEIN C, PROTEIN S AND ANTITHROMBIN IN PATIENTS WITH MESENTERIC OR PORTAL VENOUS THROMBOSIS WITH OR WITHOUT HEPATIC CIRRHOSIS
Martos, L.; (...); Espana, F.
Meeting Abstract. 10.1016/S0049-3848(14)50197-1. 2014
Comparison of a new chemiluminescent immunoassay for von Willebrand factor activity with the ristocetin cofactor-induced platelet agglutination method
Cabrera, N.; (...); Aznar, J. A.
Article. 2013
Comparison of a new chemiluminescent immunoassay for von Willebrand factor activity with the ristocetin cofactor-induced platelet agglutination method.
Cabrera N; (...); Aznar JA
Article. 10.1111/hae.12203. 2013
Comparison of protocols and RNA carriers for plasma miRNA isolation. Unraveling RNA carrier influence on miRNA isolation
Ramon-Nunez, Luis A.; (...); Navarro, Silvia
Article. 10.1371/journal.pone.0187005. 2017
Characterization of variants in the glucosylceramide synthase gene and their association with type 1 Gaucher disease severity.
Alfonso P; (...); Giraldo P
Article. 10.1002/humu.22381. 2013
Differential Gene Expression of Cardiac Ion Channels in Human Dilated Cardiomyopathy
Micaela Molina-Navarro, Maria; (...); Rivera, Miguel
Article. 2013
Differential gene expression of cardiac ion channels in human dilated cardiomyopathy.
Molina-Navarro MM; (...); Rivera M
Article. 10.1371/journal.pone.0079792. 2013
Effects of oral anticoagulant therapy and haplotype 1 of the endothelial protein C receptor gene on activated protein C levels.
Medina P; (...); España F
Article. 10.1160/TH11-07-0510. 2012
Familial left ventricular noncompaction associated with a novel mutation in the alpha-cardiac actin gene.
Rodríguez-Serrano M; (...); Zorio E
Letter. 10.1016/j.rec.2014.05.015. 2014
Flecainide, a therapeutic option in a patient with long QT syndrome type 3 caused by the heterozygous V411M mutation in the SCN5A gene.
Carrasco JI; (...); Zorio E
Letter. 10.1016/j.recesp.2012.03.014. 2012
Functional analysis of the thrombomodulin gene c.1418C > T polymorphism. Its association with venous thrombosis
Bonet, E.; (...); Navarro, S.
Article. 2013
Functional Analysis of Two Haplotypes of the Human Endothelial Protein C Receptor Gene
Medina P; (...); España F
Article. 10.1161/ATVBAHA.113.302518. 2014
FUNCTIONAL ANALYSIS OF TWO HAPLOTYPES OF THE HUMAN ENDOTHELIAL PROTEIN C RECEPTOR GENE (PROCR)
Bonet, E.; (...); Navarro Rosales, S.
Meeting Abstract. 10.1016/S0049-3848(14)50053-9. 2014
Haplotypes of the endothelial protein C receptor gene and Behçet's disease.
Navarro S; (...); España F
Article. 10.1016/j.thromres.2011.07.032. 2012
Haplotypes of the endothelial protein C receptor gene and circulating protein C levels
Martos, L.; (...); Medina, P.
Article. 2013
Haplotypes of the endothelial protein C receptor gene and circulating protein C levels
Martos, Laura; (...); Espana, Francisco
Article. 10.1016/j.thromres.2012.08.026. 2012
Heart Failure Induces Significant Changes in Nuclear Pore Complex of Human Cardiomyocytes
Tarazon, Estefania; (...); Portoles, Manuel
Article. 2012
Heart failure induces significant changes in nuclear pore complex of human cardiomyocytes.
Tarazón E; (...); Portolés M
Article. 10.1371/journal.pone.0048957. 2012
Identification and validation of plasma micrornas involved in venous and arterial thrombosis
Ramon, L. A.; (...); Navarro, S.
Meeting Abstract. 2015
IDENTIFICATION OF 58 MUTATIONS (26 NEW) IN 94 OF 109 BEING TESTED WITH PROTEIN DEFICIENCY C. SETH WORKING GROUP
Fernandez-Pardo, A.; (...); Navarro, S.
Meeting Abstract. 2019
Identification of 58 Mutations (26 Novel) in 94 of 109 Symptomatic Spanish Probands with Protein C Deficiency
Martos, L; (...); Spanish Soc Thrombosis Haemostasis
Article. 10.1055/s-0039-1692440. 2019
IDENTIFICATION OF 6 MUTATIONS IN THE PROTEIN C GENE (PROC) IN A PANEL OF 83 SPANISH FAMILIES WITH PROTEIN C DEFICIENCY
Martos, L.; (...); Espana, F.
Meeting Abstract. 10.1016/S0049-3848(14)50254-X. 2014
IDENTIFICATION OF A MICRORNA PROFILE RELATED TO HYPERTROPHIC CARDIOMYOPATHY
Plana, E.; (...); Medina, P.
Meeting Abstract. 10.1016/S0049-3848(14)50064-3. 2014
Identification of a microRNA profile related to hypertrophic cardiomyopathy. PUBLICACION: THROMBOSIS RESEARCH.
Plana, E; (...); Medina, P.
Article. 2014
IDENTIFICATION OF A PLASMA MICRORNAS PROFILE INVOLVED IN ARTERIAL THROMBOSIS
Navarro, S.; (...); Espana, F.
Meeting Abstract. 10.1016/S0049-3848(14)50273-3. 2014
IDENTIFICATION OF A PLASMA MICRORNAS PROFILE INVOLVED IN VENOUS THROMBOSIS
Navarro, S.; (...); Espana, F.
Meeting Abstract. 10.1016/S0049-3848(14)50271-X. 2014
IDENTIFICATION OF A PROFILE OF CLASSES OF CIRCULATING LIPIDS ASSOCIATED WITH THE VENOUS THROMBOEMBOLISM
Fernandez-Pardo, A.; (...); Navarro, S.
Meeting Abstract. 2019
Identification of miR-29c-3p as a Robust Normalizer for Urine microRNA Studies in Bladder Cancer.
Article. 10.3390/biomedicines8110447. 2020
Identification of mutations in the protein C gene in a panel of 65 Spanish families with protein C deficiency
Martos, Laura; (...); Espana, Francisco
Article. 10.1016/j.thromres.2012.08.029. 2012
Identification of mutations in the protein C gene in a panel of 83 Spanish families with protein C deficiency
Martos, L.; (...); Navarro, S.
Article. 2013
Increase of Neutrophil Activation Markers in Venous Thrombosis-Contribution of Circulating Activated Protein C
Martos L; (...); Medina P
Article. 10.3390/ijms21165651. 2020
Increased circulating dna, calprotectin and mieloperoxidase, as neutrophil extracellular trap markers, are risk factors for deep vein thrombosis
Martos, L.; (...); Medina, P.
Meeting Abstract. 2015
INCREASED LEVELS OF FREE CIRCULATING DNA AND DNASE 1 ACTIVITY IN PLASMA IS ASSOCIATED WITH AN INCREASED RISK OF VENOUS THROMBOEMBOLISM
Oto, J.; (...); Medina, P.
Meeting Abstract. 2019
Influence of peritoneal fluid on the expression of angiogenic and proteolytic factors in cultures of endometrial cells from women with endometriosis.
Cosín R; (...); Estelles A
Article. 10.1093/humrep/dep419. 2010
Low level of the plasma sphingolipid, glucosylceramide, is associated with thrombotic diseases.
Deguchi, H; (...); Griffin, JH
Article. 10.1002/rth2.12018. 2017
Mean platelet volume does not seem to relate to thrombosis or posterior uveitis in Behcet's disease
Maria Ricart, Jose; (...); Vaya, Amparo
Article. 2013
Mean platelet volume does not seem to relate to thrombosis or posterior uveitis in Behçet's disease.
Ricart JM; (...); Vayá A
Article. 10.3233/CH-2012-1564. 2013
MicroRNA expression profile in endometriosis: its relation to angiogenesis and fibrinolytic factors
Braza-Boïls A; (...); Estellés A
Article. 10.1093/humrep/deu019. 2014
microRNAs and Markers of Neutrophil Activation as Predictors of Early Incidental Post-Surgical Pulmonary Embolism in Patients with Intracranial Tumors
Article. 10.3390/cancers12061536. 2020
MicroRNAs and Neutrophil Activation Markers Predict Venous Thrombosis in Pancreatic Ductal Adenocarcinoma and Distal Extrahepatic Cholangiocarcinoma.
Article. 10.3390/ijms21030840. 2020
microRNAs Expression in Endometriosis and Their Relation to Angiogenic Factors EDITORIAL COMMENT
Ramon, Luis A.; (...); Estelles, Amparo
Article. 10.1097/OGX.0b013e31824021f9. 2011
microRNAs expression in endometriosis and their relation to angiogenic factors.
Ramón LA; (...); Estelles A
Article. 10.1093/humrep/der025. 2011
microRNAs modulate human tissue factor pathway inhibitor-A (TFPIA) expression in response to androgens in endothelial cells
Rodriguez, A. B. A.; (...); Gonzalez-Conejero, R.
Meeting Abstract. 2015
microRNAs related to angiogenesis are dysregulated in endometrioid endometrial cancer.
Ramón LA; (...); Estellés A
Article. 10.1093/humrep/des292. 2012
microRNAs, angiogénesis and fibrinolysis in gynecological pathology
Gilabert-Estellés J; (...); Estelles A
Article. 2012
Modification of a thrombin generation test to identify new cofactors of the protein C pathway in plasma
Martos, L.; (...); Navarro, S.
Meeting Abstract. 2015
Novedades en la genética de enfermedades monogénicas hemostásicas
España F; (...); Estelles A
Article. 2011
Peritoneal Fluid Reduces Angiogenesis-Related MicroRNA Expression in Cell Cultures of Endometrial and Endometriotic Tissues from Women with Endometriosis
Braza-Boils, Aitana; (...); Estelles, Amparo
Article. 2013
Peritoneal fluid reduces angiogenesis-related microRNA expression in cell cultures of endometrial and endometriotic tissues from women with endometriosis.
Braza-Boïls A; (...); Estellés A
Article. 10.1371/journal.pone.0062370. 2013
PLASMATIC DNA STIMULATES THE GENERATION OF IN VITRO THROMBIN EVEN IN THE ABSENCE OF EXTRINSIC TISSUE FACTOR AND CAN BE REVERSED WITH DNA'S
Fernandez-Pardo, A.; (...); Medina, P.
Meeting Abstract. 2019
Plasminogen activator inhibitor-1 (PAI-1) 4 G/5 G polymorphism and endometrial cancer. Influence of PAI-1 polymorphism on tissue PAI-1 antigen and mRNA expression and tumor severity.
Gilabert-Estellés J; (...); Estellés A
Article. 10.1016/j.thromres.2011.10.007. 2012
Quantitative immunoassay for the measurement of activated protein C complexes with Alfa-2-macroglobulin (APC:alpha M-2)
Espana, F.; (...); Medina, P.
Meeting Abstract. 2015
Red Blood Cell Distribution Width in Patients With Cryptogenic Stroke
Vayá A; (...); Bautista D
Article. 10.1177/1076029614547262. 2015
Role of microRNAs in gynecological pathology.
Gilabert-Estelles J; (...); Estelles A
Article. 10.2174/092986712800269362. 2012
Role of the endotelial cell protein C receptor in thrombosis
Medina P; (...); España F
Article. 2012
The endothelial cell protein C receptor: its role in thrombosis.
Navarro S; (...); Medina P
Article. 10.1016/j.thromres.2011.08.001. 2011
The endothelial cell protein C receptor: its role in thrombosis.
Navarro S; (...); Medina P
Article. 10.1016/j.thromres.2011.08.001. 2011
The endothelial protein C receptor is essential for protein C activation in vivo
Bonet, Elena; (...); Espana, Francisco
Article. 10.1016/j.thromres.2012.08.028. 2012
The metabolic syndrome and its individual components: its association with venous thromboembolism in a Mediterranean population.
Vayá A; (...); Corella D
Article. 10.1089/met.2010.0117. 2011
Urinary microRNAs: Looking for a New Tool in Diagnosis, Prognosis, and Monitoring of Renal Cancer
Article. 10.1007/s11934-020-0962-9. 2020
Urine metabolomic analysis in clear cell and papillary renal cell carcinoma: A pilot study
Article. 10.1016/j.jprot.2020.103723. 2020
VALIDATION OF A MODEL WITH COAGULATION-RELATED MARKERS FOR THE DIAGNOSIS OF PROSTHETIC JOINT INFECTION
Oto, J.; (...); Medina, P.
Meeting Abstract. 2019
Detección Y Caracterización De Mutaciones Asociadas Con Un Mayor Riesgo De Trombosis
Autor/es: Silvia Navarro Rosales
Tesis Doctoral
Director/es: PILAR MEDINA BADENES; Francisco España Furió
Efecto Del Acenocumarol Sobre El Sistema Anticoagulante De La Proteína C
Autor/es: Ana Rosa Cid Haro
Tesis Doctoral
Director/es: PILAR MEDINA BADENES; Silvia Navarro Rosales
Estudio Del Papel De Los Micrornas En El Desarrollo De Cáncer De Próstata En Pacientes Con Hiperplasia Benigna
Autor/es: Ana Julia Oto Martínez
Tesis de Máster
Director/es: PILAR MEDINA BADENES; Silvia Navarro Rosales
Identificación De Mutaciones En El Gen De La Proteína C En Un Panel De 44 Familias Españolas Con Deficiencia De Proteína C
Autor/es: Laura Martos Marín
Tesis de Máster
Director/es: PILAR MEDINA BADENES; Silvia Navarro Rosales