TOX-IT: Identificación de biomarcadores predictivos de toxicidad en pacientes con melanoma en tratamiento con inmunoterapia.

Datos básicos

Código:
CIGE/2023/189
Protocolo:
CIGE/2023/189
EUDRACT:
NCT:
Centro:
Dotación:
19.994,00 €
Año de incio:
2024
Año de finalización:
2025
PI BIOMÉDICA AUTONÓMICO Finan. Competitiva Pública

Documentos

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Participantes

Grupos

Financiadores - Promotores

CONSELLERIA DE INNOVACIÓN, UNIVERSIDADES, CIENCIA Y SOCIEDAD DIGITAL

Resultados del Ensayo Clínico


[[Translated article]]Drug Survival in Cyclosporine Treatment for Moderate to Severe Atopic Dermatitis: Analysis of the Spanish Atopic Dermatitis Registry (BIOBADATOP).

Couselo-Rodríguez C; (...); Flórez Á

Article. 10.1016/j.ad.2023.07.028. 2024

  • Open Access.

[[Translated article]]Epidemiological, Clinical, and Allergic Profile of Psoriatic Patients. Evaluation of the Spanish Registry of Contact Dermatitis and Cutaneous Allergy (REIDAC).

Verdaguer-Faja, J.; (...); Carrascosa, J. M.

Article. 10.1016/j.ad.2024.04.013. 2024

  • Open Access.

[[Translated article]]Requirements for Accessing New Dermatology Drugs in Spain: Results of the EQUIDAD Study.

Sanchez-Diaz, M; (...); Carrascosa-Carrillo, J M

Article. 10.1016/j.ad.2024.01.019. 2024

  • Open Access.

[[Translated article]]RF-Personalized Medicine to Treat Atopic Dermatitis: In Search for Predictive Biomarkers.

Lasheras-Perez, M A, Navarro-Blanco, F, Rodriguez-Serna, M

Article. 10.1016/j.ad.2024.04.007. 2024

  • Open Access.

[Translated article] Fatal outcome in classic Kaposi's sarcoma.

Mansilla-Polo M, Botella-Estrada R

Article. 10.1016/j.ad.2024.03.015. 2024

  • Open Access.

[Translated article] Four-year Epidemiological Surveillance of the Spanish Registry of Research in Contact Dermatitis and Cutaneous Allergy: Current Situation and Trends.

Tous-Romero F; (...); Ortiz-de Frutos J

Article. 10.1016/j.ad.2024.02.006. 2024

  • Open Access.

[Translated article] RF-Longer Dupilumab Dosing Intervals in Atopic Dermatitis: Optimization or Therapeutic Failure?

Lasheras-Perez, M A, Navarro-Blanco, F, Rodriguez-Serna, M

Article. 10.1016/j.ad.2024.07.008. 2024

  • Open Access.

2-Hydroxyethyl methacrylate (2-HEMA) sensitization, a global epidemic at its peak in Spain?

Gatica-Ortega ME; (...); Borrego L

Article. 10.1111/cod.14520. 2024

  • Open Access.

A Case of Localised Immediate Hypersensitivity Reaction to Bimekizumab.

Lasheras-Perez, Miguel Antonio; (...); Ibanez-Echevarria, Ethel

Article. 10.1111/cod.14774. 2025


Allergic contact dermatitis in adults with and without atopic dermatitis: Evaluation of the Spanish Contact Dermatitis Registry (REIDAC).

Chicharro P; (...); Sánchez-Pérez J

Article. 10.1111/cod.14672. 2024


Atypical bullae in hands and trunk: An unusual suspect

Palacios-Diaz, Rodolfo David, Lasheras-Perez, Miguel Antonio, Rodriguez-Serna, Mercedes

Editorial Material. 10.1016/j.eimc.2023.12.010. 2024

  • Open Access.

Atypical bullae in hands and trunk: An unusual suspect.

Palacios-Diaz, Rodolfo David, Lasheras-Perez, Miguel Antonio, Rodriguez-Serna, Mercedes

Case Reports. 10.1016/j.eimce.2023.12.003. 2024


Correction: 'Lesion on the back of the hand in a hematopoietic stem cell transplant recipient'.

Mansilla-Polo M; (...); Botella-Estrada R

Correction. 10.1007/s15010-024-02259-0. 2024

  • Open Access.

Characterizing Hepatitis Delta in Spain and the gaps in its management.

Rodriguez-Tajes, Sergio; (...); Lens, Sabela

Article. 10.1016/j.gastrohep.2024.502222. 2024

  • Open Access.

Chikungunya fever with a positive tourniquet test: a novel description.

Mansilla-Polo M; (...); Botella-Estrada R

Article. 10.1093/ced/llae089. 2024


Delusional parasitosis (Ekbom's syndrome).

Mansilla-Polo, M, Martin-Torregrosa, D, Botella-Estrada, R

Article. 10.1016/j.semerg.2024.102423. 2024

  • Open Access.

Dermatologic Consultations for Patients Hospitalized in Non-Dermatologic Wards: Results of a 384-Patient Cross-Sectional Study From a Tertiary Referral Hospital

Mansilla-Polo, M.; (...); Botella-Estrada, R.

Letter. 10.1016/j.ad.2024.10.030. 2024

  • Open Access.

Dermatological toxicities of talquetamab, a new bispecific antibody: case series and literature review.

Mansilla-Polo M; (...); Botella-Estrada R

Letter. 10.1111/ddg.15502. 2024


Dermatological toxicities of talquetamab, a new bispecificantibody: case series and literature review

Mansilla-Polo, Miguel; (...); Botella-Estrada, Rafael

Letter. 10.1111/ddg.15502_g. 2024


Dose tapering of dupilumab in patients with persistently controlled atopic dermatitis: a Spanish multicenter cohort study

Lasheras-Pérez MA; (...); Rodríguez-Serna M

Article. 10.1111/ijd.17030. 2024

  • Open Access.

Epidemiological, Clinical, and Allergic Profile of Psoriatic Patients. Evaluation of the Spanish Registry of Contact Dermatitis and Cutaneous Allergy (REIDAC).

Verdaguer-Faja J; (...); Carrascosa JM

Article. 10.1016/j.ad.2024.02.009. 2024

  • Open Access.

Erythema Elevatum Diutinum.

Mansilla-Polo M, Botella-Estrada R

Article. 10.1016/j.ad.2023.10.042. 2024

  • Open Access.

Guselkumab, Risankizumab, and Tildrakizumab demonstrate parallel effectiveness and safety in psoriasis treatment: a head-to-head comparative study in real clinical practice.

Mansilla-Polo M; (...); Botella-Estrada R

Article. 10.1016/j.abd.2024.04.004. 2024

  • Open Access.

Histological deep margins in cutaneous squamous cell carcinoma of the scalp and risk of recurrence.

Verdaguer-Faja, Julia; (...); Jaka, Ane

Article. 10.1111/jdv.20250. 2024

  • Open Access.

Interim analysis of the multinational, post-authorization safety study (NISSO) to assess the long-term safety of sonidegib in patients with locally advanced basal cell carcinoma

Gutzmer, Ralf; (...); Hauschild, Axel

Article. 10.1186/s12885-024-13101-z. 2024

  • Open Access.

Interparietal nodule in a 49-year-old woman.

Mansilla-Polo, Miguel; (...); Botella-Estrada, Rafael

Case Reports. 10.1111/ddg.15398. 2024


Interparietaler Knoten bei einer 49-jährigen Frau

Mansilla-Polo, Miguel; (...); Botella-Estrada, Rafael

Article. 10.1111/ddg.15398_g. 2024


La eutanasia en el régimen penitenciario español.

Lasheras-Pérez MA; (...); Rodríguez-Serna M

Letter. 10.1016/j.semerg.2024.102219. 2024

  • Open Access.

'Lesion on the back of the hand in a hematopoietic stem cell transplant recipient'.

Mansilla-Polo M; (...); Botella-Estrada R

Article. 10.1007/s15010-024-02214-z. 2024


Longer dupilumab dosing intervals in atopic dermatitis: optimization or therapeutic failure?

Lasheras-Pérez MA, Navarro-Blanco F, Rodríguez-Serna M

Article. 10.1016/j.ad.2023.04.043. 2024


Melanoma and LEOPARD Syndrome: Understanding the Role of PTPN11 Mutations in Melanomagenesis.

Palacios-Diaz, Rodolfo David; (...); Botella-Estrada, Rafael

Article. 10.2340/actadv.v104.14720. 2024

  • Open Access.

Mohs micrographic surgery in immunosuppressed vs immunocompetent patients: Results of a prospective nationwide cohort study (REGESMOHS, Spanish registry of Mohs surgery).

Abril-Pérez C; (...); Botella-Estrada R

Article. 10.1111/jdv.20103. 2024

  • Open Access.

Nodular hidradenoma: Case report and brief literature review.

Mansilla-Polo, Miguel; (...); Botella-Estrada, Rafael

Article. 10.1016/j.patol.2025.100801. 2025


Oral Ruxolitinib could Increase the Aggressiveness of Cutaneous Squamous Cell Carcinomas: A 6-Patient Series

Lasheras-Perez, M. A.; (...); Botella-Estrada, R.

Letter. 10.1016/j.ad.2023.07.035. 2025


Paraoxonase I Activity and Its Relationship with Nutrition in Amyotrophic Lateral Sclerosis.

Proaño B; (...); de la Rubia Ortí JE

Article. 10.3390/antiox13081021. 2024

  • Open Access.

Patch test results to the Spanish baseline patch test series according to age groups: A multicentric prospective study from 2019 to 2023.

Pesqué D; (...); Giménez-Arnau AM

Article. 10.1111/cod.14702. 2024

  • Open Access.

Personalized medicine to treat atopic dermatitis: in search for predictive biomarkers.

Lasheras-Perez, M A, Navarro-Blanco, F, Rodriguez-Serna, M

Article. 10.1016/j.ad.2023.02.041. 2024

  • Open Access.

Pharmacogenetics of colorectal cancer in a third-level hospital in Valencia.

Comes-Raga A; (...); Herrero Cervera MJ

Article. 10.1515/almed-2024-0146. 2024

  • Open Access.

Polysensitization in the Spanish Contact Dermatitis Registry (REIDAC): A 2019-2022 prospective study with cluster and network analysis.

Pesque, David; (...); Gimenez-Arnau, Ana Maria

Article. 10.1111/jdv.19934. 2024


Porto-sinusoidal vascular liver disorder with portal hypertension: Natural History and Long-Term Outcome.

Magaz, Marta; (...); Garcia-Pagan, Juan Carlos

Article. 10.1016/j.jhep.2024.07.035. 2024


Real-life effectiveness of sofosbuvir/velpatasvir/voxilaprevir in hepatitis C patients previously treated with sofosbuvir/velpatasvir or glecaprevir/pibrentasvir.

Ruiz-Cobo, Juan Carlos; (...); Buti, Maria

Article. 10.1111/apt.18020. 2024

  • Open Access.

Real-world effectiveness and safety of bimekizumab for hidradenitis suppurativa: An ambispective observational study.

Mansilla-Polo, Miguel; (...); Botella-Estrada, Rafael

Article. 10.1111/ajd.14339. 2024

  • Open Access.

Recalcitrant Hailey-Hailey Disease With Satisfactory Response to Apremilast

Mansilla-Polo, M.; (...); Botella-Estrada, R.

Letter. 10.1016/j.ad.2024.10.025. 2024

  • Open Access.

Recalcitrant lichen planopilaris treated with upadacitinib: a case series

Lasheras-Perez, Miguel A.; (...); Botella-Estrada, Rafael

Article. 10.1111/ijd.17339. 2024


Recurrent alcohol-associated hepatitis is common and is associated with increased mortality.

Gratacos-Gines, Jordi; (...); Pose, Elisa

Article. 10.1097/HEP.0000000000000825. 2024


Refractory cutaneous lupus erythematosus successfully treated with anifrolumab: a case series.

Martin-Torregrosa, Daniel; (...); Torres-Navarro, Ignacio

Letter. 10.1111/ijd.17022. 2024


Ruxolitinib for foreign body reaction to silicone in a patient with chronic graft-versus-host disease.

Palacios-Diaz, Rodolfo David; (...); Botella-Estrada, Rafael

Letter. 10.1111/ijd.17365. 2024

  • Open Access.

Ruxolitinib oral puede aumentar la agresividad de los carcinomas escamosos cutáneos: serie de 6 pacientes.

Lasheras-Perez MA; (...); Botella-Estrada R

Article. 10.1016/j.ad.2024.10.003. 2025


Sarcoidosis cutánea tras inyecciones de plasma rico en plaquetas y maquillaje permanente de cejas.

Martín-Torregrosa D; (...); Botella-Estrada R

Article. 10.1016/j.ad.2024.10.043. 2024

  • Open Access.

Scaling and periorificial crusts in a pediatric patient.

Fayos-Gregori, Rafael; (...); Botella-Estrada, Rafael

Article. 10.1007/s15010-024-02309-7. 2024


Sensitisation to textile dyes in Spain: Epidemiological situation (2019-2022).

Hernández Fernández CP; (...); Doval IG

Article. 10.1111/cod.14513. 2024

  • Open Access.

Skin cancer risk after hematopoietic stem cell transplantation: a systematic review and meta-analysis.

Mansilla-Polo M; (...); Botella-Estrada R

Article. 10.1111/ijd.17371. 2024


Skin lesions in a lung transplant recipient

Mansilla-Polo, Miguel; (...); Botella-Estrada, Rafael

Editorial Material. 10.1016/j.eimc.2023.09.005. 2024

  • Open Access.

Skin lesions in a lung transplant recipient.

Mansilla-Polo M; (...); Botella-Estrada R

Case Reports. 10.1016/j.eimce.2023.09.005. 2024

  • Open Access.

Standard and Expanded Series Patch Testing Update by the Spanish Contact Dermatitis and Skin Allergy Research Group (GEIDAC)

Navarro-Trivino, F. J.; (...); Armario-Hita, J. C.

Article. 10.1016/j.ad.2024.05.018. 2024

  • Open Access.

Standard and Expanded Series Patch Testing Update by the Spanish Contact Dermatitis and Skin Allergy Research Group (GEIDAC).

Navarro-Triviño FJ; (...); Carlos Armario-Hita J

Article. 10.1016/j.ad.2024.03.024. 2024

  • Open Access.

Study of Microsatellite Instability by Immunohistochemistry in a Cohort of Patients With Melanoma

Diaz, Rodolfo David Palacios; (...); Estrada, Rafael Botella

Article. 10.1111/cup.14758. 2025


Successful treatment of erythema nodosum leprosum with upadacitinib and roflumilast.

Mansilla-Polo, Miguel; (...); Torres-Navarro, Ignacio

Letter. 10.1111/ijd.17293. 2024

  • Open Access.

Successful Treatment of Mogamulizumab-Associated Rash With Upadacitinib: Evidence From 2 Cases.

Martin-Torregrosa, Daniel; (...); Botella-Estrada, Rafael

Article. 10.1001/jamadermatol.2024.4582. 2024

  • Open Access.

Successful Treatment of Stimulator of Interferon Genes-Associated Vasculopathy of Infantile Onset SAVI Syndrome With Anifrolumab.

Mansilla-Polo M; (...); Botella-Estrada R

Article. 10.1001/jamadermatol.2024.2160. 2024


Sustained response to anti-TNF therapy in ASIA syndrome triggered by vaccination and filler.

Martin-Torregrosa, Daniel; (...); Rodriguez-Serna, Mercedes

Letter. 10.1111/ijd.17650. 2025


Tattoo-Associated Common Wart

Mansilla-Polo, M., Llavador-Ros, M., Botella-Estrada, R.

Editorial Material. 10.1016/j.ad.2024.05.001. 2024

  • Open Access.

Treatment of atopic dermatitis with abrocitinib in real practice in Spain: efficacy and safety results from a 24-week multicenter study

Armario-Hita, Jose Carlos; (...); Ruiz-Villaverde, Ricardo

Article. 10.1111/ijd.17344. 2024

  • Open Access.

Treatment of palmoplantar psoriasis with oral roflumilast: a case series.

Lasheras-Perez, Miguel Antonio; (...); Botella-Estrada, Rafael

Article. 10.1093/ced/llae229. 2024


Use of an electrospun bioveil is safe and does not decrease skin graft take on burn wounds: A randomised, controlled clinical trial.

Perez-Del-Caz, Maria Dolores; (...); Perez-Plaza, Aranzazu

Article. 10.1016/j.burns.2025.107427. 2025


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