ENSAYO CLÍNICO DOBLE-CIEGO, CONTROLADO CON PLACEBO, ALEATORIZADO, FASE IB/IIA, DE APTOLL PARA EL TRATAMIENTO DE PACIENTES CON ICTUS ISQUÉMICO AGUDO.

Datos básicos

Código:
APRIL
Protocolo:
APRIL
EUDRACT:
2020-002059-38
NCT:
Centro:
HOSPITAL UNIVERSITARI I POLITÈCNIC LA FE
Dotación:
Año de incio:
2021
Año de finalización:
2022
ENSAYO CLÍNICO

Documentos

  • No hay documentos

Participantes

Grupos

Financiadores - Promotores

APTATARGETS S.L

Resultados del Ensayo Clínico


Association of cholesterol levels with hemorrhagic transformation and cerebral edema after reperfusion therapies.

Escudero-Martinez, Irene; (...); Ahmed, Niaz

Article. 10.1177/23969873221148229. 2023

  • Open Access.

Association of statin pre-treatment with baseline stroke severity and outcome in patients with acute ischemic stroke and received reperfusion treatment: An observational study.

Escudero-Martinez, Irene; (...); Ahmed, Niaz

Article. 10.1177/17474930221095965. 2022


Atrial fibrillation and stroke: A review and new insights.

Escudero-Martinez, Irene, Morales-Caba, Lluis, Segura, Tomas

Article. 10.1016/j.tcm.2021.12.001. 2021


Automatic etiological classification of stroke thrombus digital photographs using a deep learning model

Lucero-Garofano, Alvaro; (...); Manjon, Jose V.

Article. 10.3389/fneur.2025.1534845. 2025

  • Open Access.

Clot Composition Analysis as a Diagnostic Tool to Gain Insight into Ischemic Stroke Etiology: A Systematic Review

Aliena-Valero, Alicia; (...); Salom, Juan B.

Article. 10.5853/jos.2021.02306. 2021

  • Open Access.

Common and specific proteins and pathways in heart and cerebral ischemia

Pala, Elena; (...); Montaner, Joan

Article. 10.1016/j.jstrokecerebrovasdis.2023.107467. 2024


Distal Access Catheter Improves Balloon Guide and Stent Retriever Thrombectomy Outcomes in Nonagenarians.

Puig, Josep; (...); Blasco, Jordi

Article. 10.1111/jon.70012. 2025


Enhancing the First-Pass Effect in Acute Stroke: The Impact of Stent Retriever Characteristics

Murias, Eduardo; (...); Vega, Pedro

Article. 10.3390/jcm13113123. 2024

  • Open Access.

Expanding the Clinical Spectrum of DRP2-Associated Charcot-Marie-Tooth Disease.

Sivera R; (...); Sevilla T

Article. 10.1212/WNL.0000000000209174. 2024


HIGH CELL-FREE HEMOGLOBIN AND IRON LEVELS IN CLOTS OF COVID-19 STROKE PATIENTS: A NOVEL MECHANISM LINKED TO SARS-COV-2 INDUCED PROTHROMBOTIC STATE

Paya, M.; (...); Segura, T.

Meeting Abstract. 2024


Proprotein convertase subtilisin/kexin type 9 inhibitors in secondary prevention of vascular events in patients with stroke: Consensus document and practice guidance.

Gil-Núñez A; (...); Palacio E

Practice Guideline. 10.1016/j.nrleng.2020.11.014. 2022

  • Open Access.

Reperfusion By Endovascular Thrombectomy And Early Cerebral Edema In Anterior Circulation Stroke: Results From The Sits- International Stroke Thrombectomy Registry.

Thoren, Magnus; (...); Ahmed, Niaz

Article. 10.1177/17474930231180451. 2023

  • Open Access.

Reperfusion therapy in acute ischaemic stroke due to cervical and cerebral artery dissection: Results from a Spanish multicentre study.

Campo-Caballero D; (...); Serena J

Article. 10.1016/j.nrleng.2020.10.012. 2023


Role of the nigrosome 1 absence as a biomarker in amyotrophic lateral sclerosis

Isabel Moreno-Gambin, Maria; (...); Vázquez-Costa JF

Article. 10.1007/s00415-021-10729-w. 2021

  • Open Access.

Safety and Efficacy of ApTOLL in Patients With Ischemic Stroke Undergoing Endovascular Treatment: A Phase 1/2 Randomized Clinical Trial.

Hernandez-Jimenez, Macarena; (...); Ribo, Marc

Article. 10.1001/jamaneurol.2023.1660. 2023

  • Open Access.

Safety and efficacy of tirofiban in acute ischemic stroke due to tandem lesions undergoing mechanical thrombectomy: A multicenter randomized clinical trial (ATILA) protocol.

Medina-Rodriguez, Manuel; (...); Zapata-Arriaza, Elena

Article. 10.1177/23969873221146383. 2023

  • Open Access.

Statistical analysis plan for the multicenter, open, randomized controlled clinical trial to assess the efficacy and safety of intravenous tirofiban vs aspirin in acute ischemic stroke due to tandem lesion, undergoing recanalization therapy by endovascular treatment (ATILA trial)

Zapata-Arriaza, Elena; (...); Gonzalez Garcia, Alejandro

Article. 10.1186/s13063-023-07817-9. 2024

  • Open Access.

The cross-sectional area of the median nerve: An independent prognostic biomarker in amyotrophic lateral sclerosis.

Martinez-Paya, J J; (...); Vazquez-Costa, J F

Article. 10.1016/j.nrleng.2024.07.003. 2024

  • Open Access.

The pCONUS2 and pCONUS2 HPC Neck Bridging Devices : Results from an International Multicenter Retrospective Study.

Morales-Caba, L.; (...); Lylyk, P.

Article. 10.1007/s00062-022-01191-w. 2022

  • Open Access.

Campos de estudio

Compartir