ENSAYO CLÍNICO DOBLE-CIEGO, CONTROLADO CON PLACEBO, ALEATORIZADO, FASE IB/IIA, DE APTOLL PARA EL TRATAMIENTO DE PACIENTES CON ICTUS ISQUÉMICO AGUDO.
Datos básicos
- Código:
- APRIL
- Protocolo:
- APRIL
- EUDRACT:
- 2020-002059-38
- NCT:
- Centro:
- HOSPITAL UNIVERSITARI I POLITÈCNIC LA FE
- Dotación:
- Año de incio:
- 2021
- Año de finalización:
- 2022
Documentos
- No hay documentos
Participantes
Grupos
Financiadores - Promotores
Resultados del Ensayo Clínico
Association of cholesterol levels with hemorrhagic transformation and cerebral edema after reperfusion therapies.
Escudero-Martinez, Irene; (...); Ahmed, Niaz
Article. 10.1177/23969873221148229. 2023
Association of statin pre-treatment with baseline stroke severity and outcome in patients with acute ischemic stroke and received reperfusion treatment: An observational study.
Escudero-Martinez, Irene; (...); Ahmed, Niaz
Article. 10.1177/17474930221095965. 2022
Atrial fibrillation and stroke: A review and new insights.
Escudero-Martinez, Irene, Morales-Caba, Lluis, Segura, Tomas
Article. 10.1016/j.tcm.2021.12.001. 2021
Automatic etiological classification of stroke thrombus digital photographs using a deep learning model
Lucero-Garofano, Alvaro; (...); Manjon, Jose V.
Article. 10.3389/fneur.2025.1534845. 2025
Clot Composition Analysis as a Diagnostic Tool to Gain Insight into Ischemic Stroke Etiology: A Systematic Review
Aliena-Valero, Alicia; (...); Salom, Juan B.
Article. 10.5853/jos.2021.02306. 2021
Common and specific proteins and pathways in heart and cerebral ischemia
Pala, Elena; (...); Montaner, Joan
Article. 10.1016/j.jstrokecerebrovasdis.2023.107467. 2024
Distal Access Catheter Improves Balloon Guide and Stent Retriever Thrombectomy Outcomes in Nonagenarians.
Puig, Josep; (...); Blasco, Jordi
Article. 10.1111/jon.70012. 2025
Enhancing the First-Pass Effect in Acute Stroke: The Impact of Stent Retriever Characteristics
Murias, Eduardo; (...); Vega, Pedro
Article. 10.3390/jcm13113123. 2024
Expanding the Clinical Spectrum of DRP2-Associated Charcot-Marie-Tooth Disease.
Article. 10.1212/WNL.0000000000209174. 2024
HIGH CELL-FREE HEMOGLOBIN AND IRON LEVELS IN CLOTS OF COVID-19 STROKE PATIENTS: A NOVEL MECHANISM LINKED TO SARS-COV-2 INDUCED PROTHROMBOTIC STATE
Paya, M.; (...); Segura, T.
Meeting Abstract. 2024
Proprotein convertase subtilisin/kexin type 9 inhibitors in secondary prevention of vascular events in patients with stroke: Consensus document and practice guidance.
Gil-Núñez A; (...); Palacio E
Practice Guideline. 10.1016/j.nrleng.2020.11.014. 2022
Reperfusion By Endovascular Thrombectomy And Early Cerebral Edema In Anterior Circulation Stroke: Results From The Sits- International Stroke Thrombectomy Registry.
Thoren, Magnus; (...); Ahmed, Niaz
Article. 10.1177/17474930231180451. 2023
Reperfusion therapy in acute ischaemic stroke due to cervical and cerebral artery dissection: Results from a Spanish multicentre study.
Campo-Caballero D; (...); Serena J
Article. 10.1016/j.nrleng.2020.10.012. 2023
Role of the nigrosome 1 absence as a biomarker in amyotrophic lateral sclerosis
Isabel Moreno-Gambin, Maria; (...); Vázquez-Costa JF
Article. 10.1007/s00415-021-10729-w. 2021
Safety and Efficacy of ApTOLL in Patients With Ischemic Stroke Undergoing Endovascular Treatment: A Phase 1/2 Randomized Clinical Trial.
Hernandez-Jimenez, Macarena; (...); Ribo, Marc
Article. 10.1001/jamaneurol.2023.1660. 2023
Safety and efficacy of tirofiban in acute ischemic stroke due to tandem lesions undergoing mechanical thrombectomy: A multicenter randomized clinical trial (ATILA) protocol.
Medina-Rodriguez, Manuel; (...); Zapata-Arriaza, Elena
Article. 10.1177/23969873221146383. 2023
Statistical analysis plan for the multicenter, open, randomized controlled clinical trial to assess the efficacy and safety of intravenous tirofiban vs aspirin in acute ischemic stroke due to tandem lesion, undergoing recanalization therapy by endovascular treatment (ATILA trial)
Zapata-Arriaza, Elena; (...); Gonzalez Garcia, Alejandro
Article. 10.1186/s13063-023-07817-9. 2024
The cross-sectional area of the median nerve: An independent prognostic biomarker in amyotrophic lateral sclerosis.
Martinez-Paya, J J; (...); Vazquez-Costa, J F
Article. 10.1016/j.nrleng.2024.07.003. 2024
The pCONUS2 and pCONUS2 HPC Neck Bridging Devices : Results from an International Multicenter Retrospective Study.
Morales-Caba, L.; (...); Lylyk, P.
Article. 10.1007/s00062-022-01191-w. 2022