ESTUDIO DE SUPERIORIDAD, FASE III, MULTICÉNTRICO, ALEATORIZADO, DOBLE-CIEGO, DOBLE SIMULACIÓN, CON COMPARADOR ACTIVO Y DIRIGIDO POR EVENTOS, QUE COMPARA RIVAROXABAN 15 MG EN UNA TOMA DIARIA CON ASPIRINA 100 MG, EN LA PREVENCIÓN SECUNDARIA DE ACCIDENTE CEREBROVASCULAR Y EMBOLIA SISTÉMICA EN PACIENTES QUE HAN SUFRIDO UN ACCIDENTE CEREBROVASCULAR EMBÓLICO DE ETIOLOGÍA INDETERMINADA (ACEI) (NAVIGATE ESUS).

Datos básicos

Protocolo:
BAY59-7939/16573
EUDRACT:
2013-000768-27
NCT:
Centro:
HOSPITAL UNIVERSITARI I POLITÈCNIC LA FE
Año de incio:
2015
Año de finalización:
ENSAYO CLÍNICO

Documentos

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Participantes

Grupos

Financiadores - Promotores

BAYER AG

Resultados del Ensayo Clínico


Altered cerebral blood flow velocity features in fibromyalgia patients in resting-state conditions

Rodriguez, A; (...); Rey, B

Article. 10.1371/journal.pone.0180253. 2017

  • Open Access.

Association of High Serum Levels of Growth Factors with Good Outcome in Ischemic Stroke: a Multicenter Study.

Sobrino T; (...); Castillo J

Article. 10.1007/s12975-019-00747-2. 2020

  • Open Access.

Atrial fibrillation and stroke: A review and new insights.

Escudero-Martinez, Irene, Morales-Caba, Lluis, Segura, Tomas

Article. 10.1016/j.tcm.2021.12.001. 2021


Automatic etiological classification of stroke thrombus digital photographs using a deep learning model

Lucero-Garofano, Alvaro; (...); Manjon, Jose V.

Article. 10.3389/fneur.2025.1534845. 2025

  • Open Access.

Central Nervous System Involvement in Epstein-Barr Virus-Related Post-Transplant Lymphoproliferative Disorders after Allogeneic Hematopoietic Stem Cell Transplantation.

Balaguer-Rosello, Aitana; (...); Sanz, Jaime

Article. 10.1016/j.jtct.2020.12.019. 2021

  • Open Access.

Circulating MicroRNAs as Novel Biomarkers of Stenosis Progression in Asymptomatic Carotid Stenosis

Dolz, S; (...); Lago, A

Article. 10.1161/STROKEAHA.116.013650. 2017


Clinical trajectories of patients with multiple sclerosis from onset and their relationship with serum neurofilament light chain levels

Quintanilla-Bordas, Carlos; (...); Casanova, Bonaventura

Article. 10.3389/fneur.2024.1477335. 2024

  • Open Access.

Clot Composition Analysis as a Diagnostic Tool to Gain Insight into Ischemic Stroke Etiology: A Systematic Review

Aliena-Valero, Alicia; (...); Salom, Juan B.

Article. 10.5853/jos.2021.02306. 2021

  • Open Access.

COGNITIVE FUNCTION FOLLOWING AN INTRACEREBRAL HEMORRHAGE ASSOCIATED WITH CEREBRAL AMYLOID ANGIOPATHY.

Gimenez, C; (...); Lago, A

Meeting Abstract. 2020


Comparative Assessment of Simoa and Lumipulse for Measuring Serum Neurofilament Light Chain in Multiple Sclerosis Patients

Gasque-Rubio, Raquel; (...); Perez-Miralles, Francisco

Article. 10.1155/2024/1950913. 2024

  • Open Access.

Characterisation of DWI-MRI confirmed cerebral infarcts in patients with subarachnoid haemorrhage and their association with MMP-9 levels

Lago A; (...); Parkhutik V

Article. 10.1179/1743132815Y.0000000045. 2015


Design and Validation of an FPGA-Based Configurable Transcranial Doppler Neurofeedback System for Chronic Pain Patients

Rey, B; (...); Monzo, JM

Article. 10.3390/s18072278. 2018

  • Open Access.

Distal Access Catheter Improves Balloon Guide and Stent Retriever Thrombectomy Outcomes in Nonagenarians.

Puig, Josep; (...); Blasco, Jordi

Article. 10.1111/jon.70012. 2025


Downstream Migration and Fragmentation of a Spontaneous Calcific Embolus after Thrombolysis in a Patient with Ischemic Stroke

Lopez-Cuevas, R, Lago, A, Tembl, JI

Article. 10.1016/j.jstrokecerebrovasdis.2016.06.010. 2016


Eculizumab for a catastrophic relapse in NMOSD: case report.

Gorriz, David; (...); Casanova, Bonaventura

Article. 10.1007/s10072-023-06971-x. 2023


Elevation of serum neurofilament light-chain levels disclose possible occult progressive multifocal leukoencephalopathy and immune reconstitution syndrome in a patient receiving ozanimod: a case report.

Quintanilla-Bordás C; (...); Pérez-Miralles FC

Case Reports. 10.3389/fimmu.2024.1465678. 2024

  • Open Access.

Enhancing the First-Pass Effect in Acute Stroke: The Impact of Stent Retriever Characteristics

Murias, Eduardo; (...); Vega, Pedro

Article. 10.3390/jcm13113123. 2024

  • Open Access.

Expanding the Clinical Spectrum of DRP2-Associated Charcot-Marie-Tooth Disease.

Sivera R; (...); Sevilla T

Article. 10.1212/WNL.0000000000209174. 2024


Functional Outcome of Intravenous Thrombolysis in Patients With Lacunar Infarcts in the WAKE-UP Trial

Barow, E; (...); WAKE-UP Investigators

Article. 10.1001/jamaneurol.2019.0351. 2019

  • Open Access.

Genetic and constitutional factors are major contributors to substantia nigra hyperechogenicity

Vazquez-Costa, JF; (...); Sevilla, T

Article. 10.1038/s41598-017-07835-z. 2017

  • Open Access.

HIGH CELL-FREE HEMOGLOBIN AND IRON LEVELS IN CLOTS OF COVID-19 STROKE PATIENTS: A NOVEL MECHANISM LINKED TO SARS-COV-2 INDUCED PROTHROMBOTIC STATE

Paya, M.; (...); Segura, T.

Meeting Abstract. 2024


Increased pulsatility index supports diagnosis of vascular parkinsonism versus idiopathic Parkinson's disease.

Caba LM; (...); Martin AL

Article. 10.1016/j.nrl.2017.10.008. 2017

  • Open Access.

Information behaviour of the millennial generation: a scoping review of medical residents and their use of social media.

González-Teruel A, Campos-Peláez MI, Fortea-Cabo G

Review. 10.1111/hir.12306. 2020


Intra-plaque calcium and its relation with the progression of carotid atheromatous disease.

Miralles, Manuel; (...); Plana, Emma

Article. 10.23736/S0392-9590.22.04872-6. 2022


MUSCULAR ECHOVARIATION: A NEW BIOMARKER IN AMYOTROPHIC LATERAL SCLEROSIS

Martinez-Paya, JJ; (...); Medina-Mirapeix, F

Article. 10.1016/j.ultrasmedbio.2017.02.002. 2017


Neutrophil extracellular traps are increased in patients with acute ischemic stroke: prognostic significance

Valles, Juana; (...); Moscardo, Antonio

Article. 10.1160/TH17-02-0130. 2017


New insights into the pathophysiology of fasciculations in amyotrophic lateral sclerosis: An ultrasound study

Vazquez-Costa, JF; (...); Sevilla, T

Article. 10.1016/j.clinph.2018.09.014. 2018


NFL during acute spinal cord lesions in MS: a hurdle for the detection of inflammatory activity.

Alcala, C.; (...); Casanova, B.

Article. 10.1007/s00415-021-10926-7. 2022


One-year prognosis of non-traumatic cortical subarachnoid haemorrhage: A prospective series of 34 patients.

Galiano Blancart RF; (...); Lago Martín A

Article. 10.1016/j.nrl.2017.12.008. 2018

  • Open Access.

Pre-Existing Cerebral Small Vessel Disease Limits Early Recovery in Patients with Acute Lacunar Infarct.

Gómez-Choco M; (...); Serena J

Article. 10.1016/j.jstrokecerebrovasdis.2019.104312. 2019


Proprotein convertase subtilisin/kexin type 9 inhibitors in secondary prevention of vascular events in patients with stroke: Consensus document and practice guidance.

Gil-Núñez A; (...); Palacio E

Practice Guideline. 10.1016/j.nrleng.2020.11.014. 2022

  • Open Access.

Proprotein convertase subtilisin/kexin type 9 inhibitors in secondary prevention of vascular events in patients with stroke: Consensus document and practice guidance.

Gil-Nunez, A.; (...); Palacio, E.

Article. 10.1016/j.nrl.2020.11.006. 2022

  • Open Access.

Quantitative Muscle Ultrasonography Using Textural Analysis in Amyotrophic Lateral Sclerosis

Martinez-Paya, JJ; (...); Medina-Mirapeix, F

Article. 10.1177/0161734617711370. 2017


Quantitative neuromuscular ultrasound analysis as biomarkers in amyotrophic lateral sclerosis

Rios-Diaz, J; (...); Martinez-Paya, JJ

Article. 10.1007/s00330-018-5943-8. 2019


Renal function's impact on serum neurofilament levels in patients with multiple sclerosis: an exploratory analysis.

Tortosa-Carreres, Jordi; (...); Perez-Miralles, Francisco

Article. 10.1007/s10072-024-07772-6. 2024


Reperfusion therapy in acute ischaemic stroke due to cervical and cerebral artery dissection: Results from a Spanish multicentre study.

Campo-Caballero D; (...); Serena J

Article. 10.1016/j.nrleng.2020.10.012. 2023


Reperfusion treatment in acute ischaemic stroke due to cervical and cerebral artery dissection: results of a Spanish national multicentre study.

Campo-Caballero D; (...); Serena J

Article. 10.1016/j.nrl.2020.10.016. 2020

  • Open Access.

Role of the nigrosome 1 absence as a biomarker in amyotrophic lateral sclerosis

Isabel Moreno-Gambin, Maria; (...); Vázquez-Costa JF

Article. 10.1007/s00415-021-10729-w. 2021

  • Open Access.

Safety and Efficacy of ApTOLL in Patients With Ischemic Stroke Undergoing Endovascular Treatment: A Phase 1/2 Randomized Clinical Trial.

Hernandez-Jimenez, Macarena; (...); Ribo, Marc

Article. 10.1001/jamaneurol.2023.1660. 2023

  • Open Access.

Short- and long-term outcomes in non-aneurysmal non-perimesencephalic subarachnoid hemorrhage

Lago A; (...); Parkhutik V

Article. 10.1080/01616412.2016.1200306. 2016


Stroke and temporal arteritis: A study of 6 cases.

Lago A; (...); Aparici F

Article. 10.1016/j.nrl.2017.06.003. 2020

  • Open Access.

Successful systemic fibrinolysis in a patient with bacterial endocarditis

Gorriz, D; (...); Lago, A

Letter. 10.33588/rn.6209.2015331. 2016


Tendencies in cerebral aneurism treatment: Analysis of a hospital series

Lago, A; (...); Parkhutik, V

Article. 10.1016/j.nrl.2015.12.011. 2017

  • Open Access.

Tendencies in cerebral aneurism treatment: Analysis of a hospital series (vol 32, pg 371, 2017)

Lago, A; (...); Parkhutik, V

Correction. 10.1016/j.nrl.2017.07.003. 2017

  • Open Access.

The cross-sectional area of the median nerve: An independent prognostic biomarker in amyotrophic lateral sclerosis.

Martinez-Paya, J J; (...); Vazquez-Costa, J F

Article. 10.1016/j.nrleng.2024.07.003. 2024

  • Open Access.

The pCONUS2 and pCONUS2 HPC Neck Bridging Devices : Results from an International Multicenter Retrospective Study.

Morales-Caba, L.; (...); Lylyk, P.

Article. 10.1007/s00062-022-01191-w. 2022

  • Open Access.

The width of the third ventricle associates with cognition and behaviour in motor neuron disease

Vazquez-Costa, JF; (...); Sevilla, T

Article. 10.1111/ane.13022. 2019

  • Open Access.

Transcranial sonography in atypical parkinsonism: How reliable is it in real clinical practice? A multicentre comprehensive study.

Alonso-Canovas A; (...); Walter U

Article. 10.1016/j.parkreldis.2019.09.032. 2019


Transcranial ultrasound in atypical parkinsonism: how reliable is it in real clinical practice? A multi-centre comprehensive study

Canovas, AA; (...); Walter, U

Meeting Abstract. 2019


Urgent stroke care in hospitals with a stroke unit. Quick Project

Masjuan, J; (...); Zandio, B

Article. 10.33588/rn.6207.2015390. 2016


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