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Lymph Node Dissection in Patients with Melanoma and Sentinel Lymph Node Metastasis: An Updated, Evidence-Based Decision Algorithm

Fecha de publicación:

Autores de IIS La Fe

Participantes ajenos a IIS La Fe

  • Moreno-Ramirez, D
  • Boada, A
  • Ferrandiz, L
  • Samaniego, E
  • Carretero, G
  • Nagore, E
  • Redondo, P
  • Ortiz-Romero, P
  • Malvehy, J
  • Miembros Grp Espanol Dermato-Oncol
  • Academia Espanola Dermatologia Ven

Grupos

Abstract

Recent publication of the results of clinical trials in which lymph node dissection was not associated with any survival benefit in patients with sentinel node metastasis makes it necessary to reconsider the treatment of patients with melanoma. This article provides an update on the available evidence on the diverse factors (routes of metastatic spread, predictors, adjuvant therapy, etc.) that must be considered when treating patients with sentinel node-positive melanoma. The authors propose a decision-making algorithm for use in this clinical setting. The current evidence no longer supports lymph node dissection in patients with Low-risk sentinel node metastasis (sentinel node tumor load <= 1 mm). (C) 2018 AEDV. Published by Elsevier Espana, S.L.U. All rights reserved.

Datos de la publicación

ISSN/ISSNe:
0001-7310, 1578-2190

Actas Dermo-Sifiliograficas  ELSEVIER ESPANA

Tipo:
Article
Páginas:
390-398
PubMed:
29650221
Factor de Impacto:
0,291 SCImago ℠
Cuartil:
Q3 SCImago ℠

Citas Recibidas en Web of Science: 3

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Keywords

  • Melanoma; Lymph node dissection; Sentinel lymph biopsy; Adjuvant therapy

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