Portal de investigación
Ovarian manipulation in ART: going beyond physiological standards to provide best clinical outcomes
Fecha de publicación:
Autores de IIS La Fe
Grupos
Abstract
Current knowledge on ovarian physiology has challenged the traditional concept of folliculogenesis, creating the basis for novel ovarian stimulation protocols in assisted reproduction technology. The purpose of this review was to evaluate the efficacy of novel clinical interventions that could aid clinicians in individualizing their protocols to patients' characteristics and personal situations. We conducted a literature review of the available evidence on new approaches for ovarian stimulation from both retrospective and prospective studies in the PubMed database. Here, we present some of the most important interventions, including follicle growth in the gonadotropin-independent and dependent stage, manipulation of estradiol production throughout ovarian stimulation, control of mid-cycle gonadotropin surges, and luteal phase support after different stimulation protocols and trigger agents. The latest research on IVF has moved physicians away from the classical physiology, allowing the development of new strategies to decouple organ functions from the female reproductive system and challenging the traditional concept of IVF.
Datos de la publicación
- ISSN/ISSNe:
- 1058-0468, 1573-7330
- Tipo:
- Editorial Material
- Páginas:
- 1751-1762
- PubMed:
- 30056596
- Factor de Impacto:
- 1,247 SCImago ℠
- Cuartil:
- Q1 SCImago ℠
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS SPRINGER/PLENUM PUBLISHERS
Citas Recibidas en Web of Science: 10
Documentos
- No hay documentos
Filiaciones
Keywords
- Double stimulation; Dual triggering; Fertility preservation; Luteal phase ovarian stimulation; Poor responders; Random-start ovarian stimulation
Proyectos y Estudios Clínicos
ESTUDIO DE LA ENFERMEDAD METASTASICA EN EL TEJIDO OVARICO CRIOPRESERVADO DE MUJERES CON CANCER DE MAMA
Investigador Principal: ANTONIO PELLICER MARTÍNEZ
PI08/90483 . INSTITUTO DE SALUD CARLOS III . 2009
CONTRATO POSTDOCTORAL DE INVESTIGACION SARA BORRELL
CD11/00292 . INSTITUTO DE SALUD CARLOS III; FUNDACIÓN PARA LA INVESTIGACIÓN DEL HOSPITAL UNIVERSITARIO LA FE DE LA COMUNIDAD VALENCIANA . 2012
CONTRATO POSTDOCTORAL DE INVESTIGACION SARA BORELL
CD12/00568 . INSTITUTO DE SALUD CARLOS III; FUNDACIÓN PARA LA INVESTIGACIÓN DEL HOSPITAL UNIVERSITARIO LA FE DE LA COMUNIDAD VALENCIANA . 2013
CONTRATO POST FSE (RIO HORTEGA)
CM13/00191 . INSTITUTO DE SALUD CARLOS III; FUNDACIÓN PARA LA INVESTIGACIÓN DEL HOSPITAL UNIVERSITARIO LA FE DE LA COMUNIDAD VALENCIANA . 2014
CONTRATO POSTDOCTORAL DE INVESTIGACION SARA BORRELL
Investigador Principal: ANTONIO PELLICER MARTÍNEZ
CD15/00058 . INSTITUTO DE SALUD CARLOS III; FUNDACIÓN PARA LA INVESTIGACIÓN DEL HOSPITAL UNIVERSITARIO LA FE DE LA COMUNIDAD VALENCIANA . 2016
TRAMIENTO COMBINADO DE VITAMINA D CON AGNRH SOBRE EL CRECIMIENTO DE LOS MIOMAS UTERINOS
Investigador Principal: ANTONIO PELLICER MARTÍNEZ
PI15/00312 . INSTITUTO DE SALUD CARLOS III . 2016
Alternativas para la Preservacion de la fertilidad en pacientes con leucemia aguda. Maduracion in vivo mediante xenotransplante.
Investigador Principal: ANTONIO PELLICER MARTÍNEZ
GRISOLIAP/2018/029 . CONSELLERIA DE EDUCACION . 2018
Estudio de las modificaciones epigenéticas como posibles dianas terapéuticas para tratar los miomas uterinos.
Investigador Principal: ANTONIO PELLICER MARTÍNEZ
PI18/00323 . INSTITUTO DE SALUD CARLOS III . 2019
Cita
Ortega I,Garcia JA,Pellicer A. Ovarian manipulation in ART: going beyond physiological standards to provide best clinical outcomes. J Assist Reprod Genet. 2018. 35(10):p. 1751-1762. IF:2,820. (1).