Reproductive history before and after HIV diagnosis: A cross-sectional study in HIV-positive women in Spain

Fecha de publicación: 01/02/2017

Autores de IIS La Fe

Marta Montero Alonso

Autor
Enrique Bernal Delgado

Autor

Participantes ajenos a IIS La Fe

Hernando, V
Alejos, B
Perez-Elias, MJ
Blanco, JR
Giner, L
Gomez-Sirvent, JL
Iribarren, JA
Bolumar, F
and CoRIS

Grupos

Investigacion clínica en enfermedades crónicas e Infección por el VIH

Investigador establecido

Marta Montero Alonso

Abstract

The aim of this study is to examine the reproductive history of human immunodeficiency virus (HIV)-positive women, before and after HIV diagnosis, to describe the characteristics of women with pregnancies after HIV diagnosis, and to assess the prevalence of mother-to-child transmission. A cross-sectional study was performed among women within reproductive ages (18-49) selected from the cohort in the Spanish AIDS Research Network (CoRIS). A descriptive analysis of the pregnancy outcomes was made according to women's serostatus at the moment of pregnancy and association of women's characteristics with having pregnancy after HIV diagnosis was evaluated using logistic regression models. Overall, 161 women were interviewed; of them, 86% had been pregnant at least once and 39% after HIV diagnosis. There were 347 pregnancies, 29% of them occurred after HIV diagnosis and in these, 20% were miscarriages and 29% were voluntary termination of pregnancy. There were 3 cases of mother-to-child transmission among the 56 children born from HIV-positive mothers; in these cases, women were diagnosed during delivery. Having a pregnancy after HIV diagnosis was more likely when the younger women were at the time of diagnosis: odds ratio (OR) = 1.29 (95% confidence interval 0.40-4.17) for 25 to 29 years old, OR = 0.59 (0.15-2.29) for 30 to 34 years old, OR = 0.14 (0.03-0.74) for = 35 years old, compared with those <25 years at diagnosis, who were diagnosed for = 5 years (OR = 5.27 [1.71-16.18]), who received antiretroviral treatment at some point (OR = 9.38 [1.09-80.45]), and who received information on reproductive health (OR = 4.32 [1.52-12.26]). An important number of pregnancies occurred after HIV diagnosis, reflecting a desire for motherhood in these women. Reproductive and sexual health should be tackled in medical follow-ups.

Datos de la publicación

ISSN/ISSNe:: 0025-7974, 1536-5964
Tipo:: Article
Páginas:: -
DOI:: 10.1097/MD.0000000000005991
Factor de Impacto:: 0,799 SCImago ℠
Cuartil:: Q2 SCImago ℠

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Métricas

Filiaciones

Hernando, V:: aRed de Investigación en Sida, Centro Nacional de Epidemiología, Instituto de Salud Carlos III bCIBER de Epidemiología y Salud Pública (CIBERESP) cHospital Universitario La Fe, Valencia dHospital Universitario Ramón y Cajal, Madrid eHospital Universitario San Pedro-CIBIR, Logroño fHospital Universitario de Alicante, Alicante gHospital Universitario de Canarias, Tenerife hHospital Universitario Donostia, Donostia iHospital Universitario Reina Sofia, Murcia jUniversidad de Alcalá, Alcalá de Henare

Inst Salud Carlos III, Ctr Nacl Epidemiol, Red Invest Sida, Valencia, Spain

CIBER Epidemiol & Salud Publ CIBERESP, Valencia, Spain
Alejos, B:: Inst Salud Carlos III, Ctr Nacl Epidemiol, Red Invest Sida, Valencia, Spain

CIBER Epidemiol & Salud Publ CIBERESP, Valencia, Spain
Montero, M:: Hosp Univ La Fe, Valencia, Spain
Perez-Elias, MJ:: Hosp Univ Ramon & Cajal, Madrid, Spain
Blanco, JR:: Hosp Univ San Pedro CIBIR, Logrono, Spain
Giner, L:: Hosp Univ Alicante, Alicante, Spain
Gomez-Sirvent, JL:: Hosp Univ Canarias, Tenerife, Spain
Iribarren, JA:: Hosp Univ Donostia, Donostia San Sebastian, Spain
Bernal, E:: Hosp Univ Reina Sofia, Murcia, Spain
Bolumar, F:: Univ Alcala De Henares, Madrid, Spain

CUNY, Sch Publ Hlth, Hunter Coll, New York, NY USA