Endothelial protein C receptor polymorphisms and risk of myocardial infarction.

Autores de IIS La Fe

• 

  Pilar Medina Badenes

  Autor

• Silvia Navarro Rosales

  Autor

• Jaime Corral Peñafiel

  Autor

• 

  Esther Zorio Grima

  Autor

• Amparo Estelles Cortes

  Autor

• Francisco Marin Ortuño

  Autor

• Joaquín Rueda Soriano

  Autor

• Francisco España Furio

  Autor

Participantes ajenos a IIS La Fe

• Roldán V
• Santamaría A
• Bertina RM
• RECAVA Thrombosis Groups

Grupos

• Hemostasia, Trombosis, Arteriosclerosis y Biología vascular

Abstract

Haplotypes A1 and A3 in the endothelial protein C receptor gene are tagged by the 4678G/C and 4600A/G polymorphisms, respectively, and have been reported to influence the risk of venous thromboembolism. We assessed whether these haplotypes modify the risk of premature myocardial infarction.