Residual platelet thromboxane A2 and prothrombotic effects of erythrocytes are important determinants of aspirin resistance in patients with vascular disease.

Autores de IIS La Fe

• Maria Teresa Santos Diaz

  Autor

• Juana Valles Giner

  Autor

• Aida Lago Martín

  Autor

• José Ignacio Tembl Ferrairo

  Autor

• Antonio Moscardó Martínez

  Autor

• Juan Cosin Aguilar

  Autor

Participantes ajenos a IIS La Fe

• Sánchez E

Grupos

• Hemostasia, Trombosis, Arteriosclerosis y Biología vascular

Abstract

Permanent inactivation of cyclooxygenase-1 and inhibition of platelet thromboxane A(2) (TxA(2)) constitute the main mechanisms underlying the prevention of vascular disease by aspirin.