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  3. Epidemiological, Clinical and Allergic Profile of Patients With Dyshidrotic Eczema (Acute and Recurrent Vesicular Dermatitis): Evaluation of the Spanish Registry of Research in Contact Dermatitis and Cutaneous Allergy (REIDAC)

Epidemiological, Clinical and Allergic Profile of Patients With Dyshidrotic Eczema (Acute and Recurrent Vesicular Dermatitis): Evaluation of the Spanish Registry of Research in Contact Dermatitis and Cutaneous Allergy (REIDAC)

Fecha de publicación: Fecha Ahead of Print:

Autores de IIS La Fe

Participantes ajenos a IIS La Fe

  • Sánchez-Gilo A.
  • Gómez de la Fuente E.
  • Giménez-Arnau A.M.
  • Silvestre-Salvador J.F.
  • Mercader-García P.
  • Sanz-Sánchez T.
  • Zaragoza-Ninet V.
  • Córdoba-Guijarro S.
  • Miquel-Miquel J.
  • González-Pérez R.
  • Ruiz-Gonzalez I.
  • Serra-Baldrich E.
  • Carrascosa-Carrillo J.M.
  • Ortiz de Frutos F.J.
  • Gatica-Ortega M.E.
  • Paredes-Suárez C.
  • Navarro-Triviño F.J.
  • Chicharro P.
  • Pastor-Nieto M.A.
  • Barasoain M.A.
  • Pereyra-Rodríguez J.-J.
  • Melé-Ninot G.
  • Sánchez-Pedreño Guillén P.
  • Elosua-González M.
  • Descalzo M.Á.
  • García-Doval I.
  • Barba-Martín R.
  • Borrego L.

Grupos

Abstract

Background: Dyshidrotic eczema (DE), also termed acute and recurrent vesicular dermatitis, is a vesicular clinical pattern of hand eczema (HE) with heterogeneous aetiologies. Objectives: To characterise the clinical-allergological profile of patients with DE and to compare it with non-DE HE subtypes. Methods: A multicentre, retrospective, observational study was conducted using data from the Spanish Contact Dermatitis Registry (2019–2024). Results: Of 4378 patients with HE, 559 were diagnosed with DE. A longer median disease duration (24 vs. 14 months) and more frequent palmoplantar involvement (16% vs. 7%) were observed in DE compared with non-DE HE. At least one positive patch test was identified in 43% of DE versus 52% in non-DE HE. Although overall sensitisation patterns were largely comparable, DE showed lower sensitisation rates to 2-HEMA, carba mix and thiuram mix. Occupational factors were less frequently implicated in DE (9% vs. 29%) compared with non-DE HE. Conclusions: Despite a high overall frequency of contact allergen sensitisation, the pattern of findings suggests that the dyshidrotic phenotype may follow a clinical course less dependent on external or occupational triggers, pointing towards a relatively greater contribution of endogenous factors compared with other HE subtypes. © 2026 The Author(s). Contact Dermatitis published by John Wiley & Sons Ltd.

Datos de la publicación

ISSN/ISSNe:
0105-1873, 1600-0536

CONTACT DERMATITIS  WILEY

Tipo:
Article
Páginas:
-
PubMed:
42144272
Enlace a otro recurso:
www.scopus.com
Factor de Impacto:
0,810 SCImago ℠
Cuartil:
Q1 SCImago ℠

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Keywords

  • acute and recurrent vesicular dermatitis; dyshidrotic eczema; epidemiological surveillance; hand eczema; patch testing; pompholyx

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