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  3. [Translated article] Clinical-Epidemiological Profile, and Treatment Response in Relation to Associated Atopic Comorbidity in Atopic Dermatitis. Experience From the BIOBADATOP Registry.

[Translated article] Clinical-Epidemiological Profile, and Treatment Response in Relation to Associated Atopic Comorbidity in Atopic Dermatitis. Experience From the BIOBADATOP Registry.

Fecha de publicación: Fecha Ahead of Print:

Autores de IIS La Fe

Participantes ajenos a IIS La Fe

  • Peris-Espino V
  • Munera-Campos M
  • Chicharro P
  • González Quesada A
  • Flórez Menéndez Á
  • de la Cueva Dobao P
  • Giménez Arnau AM
  • Gilaberte Calzada Y
  • Montero-Vilchez T
  • Silvestre Salvador JF
  • Ruiz-Villaverde R
  • Elosua-González M
  • Del Alcázar-Viladomiu E
  • Sánchez-Pérez J
  • Carretero Hernández G
  • Batalla A
  • Suh Oh HJ
  • Couselo-Rodríguez C
  • Mauleón Fernández C
  • Curto-Barredo L
  • Bertolín-Colilla M
  • Navarro-Bielsa A
  • Ballano Ruiz A
  • Arias-Santiago S
  • Sanabria-de-la-Torre R
  • Betlloch-Mas I
  • Navarro-Triviño FJ
  • Roustan Gullón G
  • Rosell-Díaz A
  • Loro-Pérez M
  • Suárez-Pérez J
  • García-Doval I
  • Descalzo-Gallego MÁ
  • Carrascosa Carrillo JM

Grupos

Abstract

BACKGROUND: Despite advances made in treatments for atopic dermatitis (AD), information on its impact and interaction with atopic comorbidities, such as asthma, rhinoconjunctivitis, and ocular disease is limited. This study aims to assess the clinical-epidemiological characteristics of patients with AD - treatment response included - while taking into consideration atopic comorbidities like these. MATERIALS AND METHODS: Data were analyzed from the multicenter BIOBADATOP registry (a prospective cohort of AD patients initiating systemic treatment). We conducted a descriptive analysis of the main characteristics collected in the registry in relation to atopic comorbidity. RESULTS: We included a total of 509 patients, mostly adults (81.9%) with severe AD (73.7%). Patients with personal atopic comorbidity (64%) more frequently exhibited flexural dermatitis (89.7% vs. 81.5%), a higher mean of previous systemic treatments (1.6 vs. 1.3), and higher baseline values on the POEM scale (19.6 vs. 17.9). Patients with familial atopic comorbidity (40.7%) had a higher incidence of pediatric/adolescent patients (24.2% vs. 13.9%) and a history of allergic rhinoconjunctivitis (61.1% vs. 47.1%). No differences regarding treatment response were observed at the 6- and 12-month follow-ups based on the presence or absence of atopic comorbidities. CONCLUSIONS: Results suggest that a history of atopic comorbidity is associated with an early onset and persistent course of AD. Although no differences were reported in the short-term treatment response, further follow-up is required to better understand the impact of comorbidities on AD.

Copyright © 2024 AEDV. Publicado por Elsevier España, S.L.U. All rights reserved.

Datos de la publicación

ISSN/ISSNe:
0001-7310, 1578-2190

Actas Dermo-Sifiliograficas  ELSEVIER ESPANA

Tipo:
Article
Páginas:
337-348
PubMed:
39938776
Factor de Impacto:
0,279 SCImago ℠
Cuartil:
Q3 SCImago ℠

Citas Recibidas en Web of Science: 1

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Keywords

  • Atopic comorbidities; Atopic dermatitis; Cohorte prospectiva; Comorbilidades atópicas; Dermatitis atópica; Prospective cohort; Tratamientos; Treatments

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