The study of deep brain structures by transcranial duplex sonography and imaging resonance correlation.

Autores de IIS La Fe

• Pilar Sahuquillo Ruiz

  Autor

• José Ignacio Tembl Ferrairo

  Autor

• Vera Parkhutik Matveeva

  Autor

• Juan Francisco Vázquez Costa

  Autor

• Isabel Sastre Bataller

  Autor

• Aida Lago Martín

  Autor

Grupos

• Hemostasia, Trombosis, Arteriosclerosis y Biología vascular

  

  Investigador Principal

  Pilar Medina Badenes

Abstract

Transcranial duplex sonography (TCS) currently provides us with images of deep brain structures with sufficient resolution. We chose 2 sonographic quantitative parameters: the diameter of the third ventricle and a measurement not used by TCS to date, the midbrain area. Their reliability and reproducibility were assessed using magnetic resonance imaging (MRI) as the reference. A total of 99 patients free from neurodegenerative disorders were examined using TCS, and both parameters were measured by 2 independent explorers. Measurements of third-ventricle diameter by TCS showed very good correlation (r = 0.80) and agreement (ICC = 0.89) with measurements obtained by MRI. Measurements of the midbrain area by TCS also provided acceptable values with moderate correlation (r = 0.36) and agreement (ICC = 0.53). Interexplorer correlation values were good (ICC = 0.98 and 0.79 for the third ventricle and midbrain areas, respectively). Further studies will be required to determine the potential diagnostic usefulness of these parameters.

Keywords

• Transcranial duplex sonography; Brain parenchyma sonography; Deep brain structures; Correlation with magnetic resonance imaging; Third ventricle diameter; Midbrain area