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  3. TXA2 synthesis and COX1-independent platelet reactivity in aspirin-treated patients soon after acute cerebral stroke or transient ischaemic attack.

TXA2 synthesis and COX1-independent platelet reactivity in aspirin-treated patients soon after acute cerebral stroke or transient ischaemic attack.

Fecha de publicación:

Autores de IIS La Fe

Grupos

Abstract

The pharmacological target of aspirin is the inhibition of cyclooxygenase-1 (COX1) and thromboxane-A2 (TX) synthesis. Very few data are available on TX assessment in patients with stroke. We studied platelet TX synthesis, COX1-independent platelet reactivity, the influence of platelet-erythrocyte interactions and the potential association between platelet responses and the severity of stroke, evaluated with a clinical score (NIHSS).

Datos de la publicación

ISSN/ISSNe:
0049-3848, 1879-2472

THROMBOSIS RESEARCH  PERGAMON-ELSEVIER SCIENCE LTD

Tipo:
Article
Páginas:
211-216
PubMed:
23830213
Factor de Impacto:
1,050 SCImago ℠
Cuartil:
Q2 SCImago ℠

Citas Recibidas en Web of Science: 10

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Keywords

  • Acute stroke, Aspirin, Cyclooxygenase-1, Platelet–erythrocyte interactions, Thromboxane A(2)

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