Circulating endothelial cells and procoagulant microparticles in patients with glioblastoma: prognostic value.

Autores de IIS La Fe

• Gaspar Reynes Muntaner

  Autor

• Virtudes Vila Liante

  Autor

• Tania Carolina Fleitas Kanonnikoff

  Autor

• Edelmiro Reganon Salvador

  Autor

• Jaime Font De Mora Sainz

  Autor

• Maria Vicente Jorda Cuevas

  Autor

• Vicenta Martinez Sales

  Autor

Grupos

• Hemostasia, Trombosis, Arteriosclerosis y Biología vascular

• Investigación Clínica y Traslacional en Cáncer

Abstract

Circulating endothelial cells and microparticles are prognostic factors in cancer. However, their prognostic and predictive value in patients with glioblastoma is unclear. The objective of this study was to investigate the potential prognostic value of circulating endothelial cells and microparticles in patients with newly diagnosed glioblastoma treated with standard radiotherapy and concomitant temozolomide. In addition, we have analyzed the methylation status of the MGMT promoter.