Biology and management of therapy-related acute promyelocytic leukemia.

Autores de IIS La Fe

• Pau Montesinos Fernández

  Autor

• Miguel Ángel Sanz Alonso

  Autor

Participantes ajenos a IIS La Fe

• Lo-Coco F
• Hasan SK

Grupos

• Hematología y Hemoterapia

Abstract

Therapy-related acute promyelocytic leukemia (t-APL) has been increasingly reported after exposure to cytotoxic and/or immunosuppressive agents given for prior malignancies or autoimmune diseases. t-APL represents both a model for better understanding human leukemogenesis and an interesting therapeutic subset which requires specific adaptations for optimal management.