ESTUDIO DE FASE 3, ALEATORIZADO Y ABIERTO QUE INVESTIGA LA EFICACIA DEL ANTICUERPO BITE® BLINATUMOMAB EN COMPARACIÓN CON EL TRATAMIENTO ESTÁNDAR DE QUIMIOTERAPIA EN SUJETOS ADULTOS CON LEUCEMIA LINFOBLÁSTICA AGUDA (LLA) DE PRECURSORES B RECIDIVANTE/REFRACTARIA (ESTUDIO TOWER).

Datos básicos

Protocolo:
00103311
EUDRACT:
2013-000536-10
NCT:
Centro:
HOSPITAL UNIVERSITARI I POLITÈCNIC LA FE
Año de incio:
2014
Año de finalización:
2016
ENSAYO CLÍNICO INTERNACIONAL

Documentos

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Participantes

Grupos

Resultados del Ensayo Clínico


[Farewell open letter to SEFH members].

Poveda Andrés JL

Editorial Material. 10.7399/fh.2015.39.6.10128. 2015

  • Open Access.

A Cutting-Edge Bioinformatics Tool for Neoantigen Identification in Unpaired RNA-Seq Samples of AML

Perez Miguez, Carlos; (...); Montesinos, Pau

Meeting Abstract. 10.1182/blood-2024-201407. 2024


A High Percentage of DNAM-1+and Low Percentage of Tactile plus NK Cells at Diagnosis Correlate with Complete Response and Survival in AML: A Sub-Analysis of the Ven-a-Qui Pethema Trial

Bergua Burgues, Juan Miguel; (...); Montesinos, Pau

Meeting Abstract. 10.1182/blood-2023-189676. 2023

  • Open Access.

A phase 2, multicenter, clinical trial of CPX-351 in older patients with secondary or high-risk acute myeloid leukemia: PETHEMA-LAMVYX.

Rodríguez-Arbolí E; (...); Montesinos P

Article. 10.1002/cncr.35618. 2024

  • Open Access.

A retrospective audit of platelet transfusion in a hematology service of a tertiary-care hospital: Effectiveness of training to improve compliance with standards

Solves P; (...); Sanz MÁ

Letter. 10.1016/j.transci.2013.11.009. 2014


A systematic review and meta-analysis of the impact of WT1 polymorphism rs16754 in the effectiveness of standard chemotherapy in patients with acute myeloid leukemia

Megías-Vericat JE; (...); Aliño SF

Article. 10.1038/tpj.2015.80. 2016


A systematic review of venetoclax for the treatment of unfit AML patients in real-world: is all that glitters gold?

Solana-Altabella A; (...); Montesinos P

Article. 10.1007/s00277-024-05891-w. 2024

  • Open Access.

ACUTE MYELOID LEUKEMIA IN PATIENTS 70 AND ABOVE. AZACITIDINE VERSUS INTENSIVE CHEMOTHERAPY

De La Fuente, A.; (...); Ramos, F.

Meeting Abstract. 2014

  • Open Access.

Acute promyelocytic leukemia: do we have a new front-line standard of treatment?

Sanz MA, Iacoboni G, Montesinos P

Article. 10.1007/s11912-013-0339-z. 2013


Adverse prognostic value of MYBL2 overexpression and association with microRNA-30 family in acute myeloid leukemia patients.

Fuster O; (...); Barragán E

Article. 10.1016/j.leukres.2013.09.015. 2013


Aflibercept in exudative age related macular degeneration refractory to ranibizumab.

Ruiz Ramos J; (...); Gallego-Pinazo R

Article. 10.1016/j.oftal.2015.07.018. 2015


All-trans retinoic acid with daunorubicin or idarubicin for risk-adapted treatment of acute promyelocytic leukaemia: a matched-pair analysis of the PETHEMA LPA-2005 and IC-APL studies

Sanz MA; (...); IC-APL and PETHEMA and HOVON Groups

Article. 10.1007/s00277-015-2393-0. 2015


Analisis de las causas de suspension de tratamiento con triple terapia antiviral en pacientes con hepatitis C.

Ruiz Ramos J; (...); Poveda Andrés JL

Abstract of Published Item. 10.7399/fh.2014.38.3.1171. 2014

  • Open Access.

Anidulafungin-Induced Alopecia

Ruiz-Ramos J; (...); Poveda-Andrés JL

Article. 10.1177/1060028014524534. 2014


Apicobasal Polarity Controls Lymphocyte Adhesion to Hepatic Epithelial Cells

Reglero-Real N; (...); Millán J

Article. 10.1016/j.celrep.2014.08.007. 2014

  • Open Access.

Arsenic trioxide-based therapy of relapsed acute promyelocytic leukemia: registry results from the European LeukemiaNet

Lengfelder E; (...); European LeukemiaNet

Article. 10.1038/leu.2015.12. 2015


Assessment of the quality of sample labelling for clinical research.

Pérez-Huertas P; (...); Poveda-Andrés JL

Article. 10.7399/fh.2016.40.2.9753. 2016

  • Open Access.

Association of SNPs with the efficacy and safety of immunosuppressant therapy after heart transplantation

Sánchez-Lázaro I; (...); Aliño SF

Article. 10.2217/pgs.15.39. 2015


Autoimmune cytopenias after umbilical cord blood transplantation in adults with hematological malignancies: a single-center experience

Sanz J; (...); Sanz GF

Article. 10.1038/bmt.2014.107. 2014


Autologous or allogeneic hematopoietic stem cell transplantation as front-line treatment for adult secondary acute myeloid leukemia patients: the PETHEMA registry experience.

Serrano, Josefina; (...); Montesinos, Pau

Article. 10.1016/j.jtct.2025.02.011. 2025


Azacitidine in older patients with acute myeloid leukemia (AML). Results from the ALMA study according to the MRC risk index score.

Falantes, Jose F.; (...); Ramos, Fernando

Meeting Abstract. 2015


Biology and management of therapy-related acute promyelocytic leukemia.

Lo-Coco F; (...); Sanz MA

Article. 10.1097/CCO.0000000000000013. 2013


Biosimilares: viejas polemicas con nuevos argumentos.

Poveda-Andrés JL, Bosó-Ribelles V

Editorial Material. 10.7399/fh.2015.39.3.8978. 2015

  • Open Access.

BLINATUMOMAB IMPROVED OVERALL SURVIVAL IN PATIENTS WITH RELAPSED OR REFRACTORY PHILADELPHIA NEGATIVE B-CELL PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA IN A RANDOMIZED, OPEN-LABEL PHASE 3 STUDY (TOWER)

Topp, M. S.; (...); Kantarjian, H.

Meeting Abstract. 2016

  • Open Access.

Bloodstream Infections in Adult Patients Undergoing Cord Blood Transplantation from Unrelated Donors after Myeloablative Conditioning Regimen

Sanz J; (...); Sanz GF

Article. 10.1016/j.bbmt.2014.12.038. 2015


Bortezomib-based induction therapy followed by intravenous busulfan-melphalan as conditioning regimen for patients with newly diagnosed multiple myeloma

Blanes M; (...); de la Rubia J

Article. 10.3109/10428194.2014.922182. 2015


Calidad y Legibilidad de la Hoja de Informacion al Paciente en Estudios con Analisis Farmacogenetico.

Ruiz Ramos J; (...); Poveda Andrés JL

Article. 2015


CIP2A high expression is a poor prognostic factor in normal karyotype acute myeloid leukemia

Barragán E; (...); Odero MD

Letter. 10.3324/haematol.2014.118117. 2015

  • Open Access.

Clinical evaluation of rituximab treatment for neuromyelitis optica

Fernández-Megía MJ; (...); Poveda-Andrés JL

Article. 10.1016/j.nrl.2014.09.001. 2015

  • Open Access.

Clinical experiences with cannabinoids in spasticity management in multiple sclerosis

Lorente Fernández L; (...); Casanova-Estruch B

Article. 10.1016/j.nrl.2013.06.014. 2014

  • Open Access.

Clonal Evolution Analysis Using Next Generation Sequencing (NGS) Panel in a Cohort of 3,025 Patients With Acute Myeloid Leukemia (AML)

Colmenares, Rafael; (...); Montesinos, Pau

Meeting Abstract. 2023


COMPARATIVE STUDY OF HEREDITARY SPHEROCYTOSIS USING FLOW CYTOMETRY AND OSMOTIC GLOBULAR FRAGILITY

Cordon Gallego, L.; (...); Sanz Alonso, M. A.

Meeting Abstract. 2015

  • Open Access.

Comparative Study of Post-Transplant Lymphoproliferative Disorders after Solid Organ Transplantation Versus Hematopoietic Stem Cell Transplantation

Romero, Samuel, Sr.; (...); Sanz, Miguel Angel

Article. 2015


Comparison of outcomes after unrelated cord blood and unmanipulated haploidentical stem cell transplantation in adults with acute leukemia

Ruggeri A; (...); ALWP-EBMT study

Article. 10.1038/leu.2015.98. 2015


Comparison of the 2022 and 2017 European LeukemiaNet risk classifications in a real-life cohort of the PETHEMA group

Sargas, Claudia; (...); Montesinos, Pau

Article. 10.1038/s41408-023-00835-5. 2023

  • Open Access.

Conventional induction and post-remission therapy in APL: Have we arrived?

Sanz MA, Iacoboni G, Montesinos P

Article. 10.1016/j.beha.2014.04.004. 2014


Cost-effectiveness of methoxy polyethylene glycolepoetin beta versus conventional epoetin in the treatment of anaemia secondary to chronic kidney disease in clinical practice

Lorente-Fernandez, L; (...); Poveda-Andres, JL

Article. 10.1136/ejhpharm-2013-000426. 2015


CHARACTERIZATION OF RECURRENTLY MUTATED GENES IN ACUTE MYELOID LEUKEMIA DE NOVO WITH NORMAL KARPOTYPE BY TARGETED MASSIVE SEQUENCING

Ibanez, M.; (...); Cervera, J.

Article. 2015

  • Open Access.

DEEP SEQUENCING OF 23 GENES DESIGNATED BY TCGA STUDY IN ACUTE MYELOID LEUKEMIA PATIENTS WITH NORMAL KARYOTYPE

Ibanez, M.; (...); Cervera, J.

Meeting Abstract. 2016

  • Open Access.

DESCRIPTIVE STUDY OF THE RECORD OF THROMBOTIC MICROANGIOPATHY IN A SINGLE CENTRE

Romero Dominguez, S.; (...); Sanz Alonso, M. A.

Meeting Abstract. 2015

  • Open Access.

Design of the randomized, Phase III, QUAZAR AML Maintenance trial of CC-486 (oral azacitidine) maintenance therapy in acute myeloid leukemia

Roboz GJ; (...); Kantarjian H

Article. 10.2217/fon.15.326. 2016


Do NPM1 and FLT3-ITD mutations modify prognosis in patients treated with non-intensive regimens?

Suárez EU; (...); Montesinos P

Article. 10.1007/s00277-024-05840-7. 2024


Dose banding aplicado a la elaboracion de antineoplasicos: una revision narrativa de la literatura.

Pérez Huertas P; (...); Poveda Andrés JL

Article. 10.7399/fh.2015.39.4.8839. 2015

  • Open Access.

Drug Interaction Between Oral Cyclosporine Modified and Iron

Domingo-Chiva, E; (...); Poveda-Andres, JL

Article. 10.1177/1060028013514734. 2014


EBV-associated post-transplant lymphoproliferative disorder after umbilical cord blood transplantation in adults with hematological diseases

Sanz J; (...); Sanz GF

Article. 10.1038/bmt.2013.190. 2014


ECONOMIC IMPACT LINKED TO THE REDUCTION OF EXACERBATIONS WHEN A TREATMENT REGIME WITH INHALED ANTIBIOTICS IS SWITCHED TO AZTREONAM LYSINE IN PATIENTS WITH CYSTIC FIBROSIS AND CHRONIC PULMONARY INFECTION CAUSED BY PSEUDOMONAS AERUGINOSA

Sole A; (...); Casado MA

Meeting Abstract. 10.1016/j.jval.2014.08.1659. 2014

  • Open Access.

Eculizumab for the treatment of pregnancy-related atypical hemolytic uremic syndrome

Cañigral C; (...); Sanz MA

Letter. 10.1007/s00277-013-1970-3. 2014


Effect of CD8(+) Cell Content on Umbilical Cord Blood Transplantation in Adults with Hematological Malignancies

Moscardó F; (...); Sanz GF

Article. 10.1016/j.bbmt.2014.06.038. 2014


EFFECT OF CYP3A5 GENOTYPE ON TACROLIMUS DOSE REQUIREMENT, NEPHROTOXICITY AND ACUTE REJECTION IN KIDNEY TRANSPLANTATION: A SYSTEMATIC REVIEW AND META-ANALYSIS OF OBSERVATIONAL STUDIES

Rojas, L.; (...); Alino, S. F.

Article. 2013


Effect of CYP3A5*3 on kidney transplant recipients treated with tacrolimus: a systematic review and meta-analysis of observational studies

Rojas L; (...); Aliño SF

Article. 10.1038/tpj.2014.38. 2015


EFFECTS OF POLYMORPHIMS OF CYP3A5 AND ABCB1 GENES ON CHRONIC NEPHROPATHY: COHORT STUDY

Rojas, L.; (...); Alino, S. F.

Article. 2013


Engraftment kinetics and graft failure after single umbilical cord blood transplantation using a myeloablative conditioning regimen

Ruggeri A; (...); Netcord

Article. 10.3324/haematol.2014.109280. 2014

  • Open Access.

Epstein-Barr virus-associated posttransplant lymphoproliferative disorder after allogeneic stem cell transplantation

Sanz J, Andreu R

Review. 10.1097/CCO.0000000000000119. 2014


Estudio de utilizacion de boceprevir y telaprevir para el tratamiento de la hepatitis C cronica.

Marrero-Álvarez P; (...); Poveda-Andrés JL

Abstract of Published Item. 10.7399/FH.2014.38.1.1128. 2014

  • Open Access.

Evolving patterns and clinical outcome of genetic studies performed at diagnosis in acute myeloid leukemia patients: Real life data from the PETHEMA Registry.

Labrador, Jorge; (...); Montesinos, Pau

Article. 10.1002/cncr.35431. 2024

  • Open Access.

Executive summary of the GESIDA/National AIDS Plan Consensus Document on antiretroviral therapy in adults infected by the human immunodeficiency virus (updated January 2015)

Expert Panel of GESIDA and the National AIDS Plan; (...); Rivero A

Article. 10.1016/j.eimc.2015.03.017. 2015


Experience in the management of immunosuppressant treatment with hepatitis C virus protease inhibitors

Ruiz Ramos J; (...); Poveda Andrés JL

Article. 10.1016/j.gastrohep.2014.05.004. 2014


EXPERTS CONSENSUS ON THE FUTURE OF RARE DISEASES CARE AND ORPHAN DRUGS ACCESS IN SPAIN: A DELPHI STUDY

Paz S; (...); Urcelay J

Meeting Abstract. 10.1016/j.jval.2015.09.2016. 2015

  • Open Access.

Exploring Potential Molecular Mechanisms of Drug Response in FLT3-ITD Negative AML Patients Treated with Quizartinib Vs Placebo Plus Standard Chemotherapy in the Quiwi Trial

Mosquera Orgueira, Adrian; (...); Montesinos, Pau

Meeting Abstract. 10.1182/blood-2023-180710. 2023


Ex-vivo T-cell depleted peripheral blood stem cell transplantation from HLA-matched sibling donors for the treatment of severe aplastic anemia

Cano-Ferri, I.; (...); Sanz, G.

Meeting Abstract. 2015


Feasibility and results of subtype-oriented protocols in older adults and fit elderly patients with acute lymphoblastic leukemia: Results of three prospective parallel trials from the PETHEMA group

Ribera, JM; (...); Spanish Soc Hematology

Article. 10.1016/j.leukres.2015.11.012. 2016


FLORENCE: a randomized, double-blind, phase III pivotal study of febuxostat versus allopurinol for the prevention of tumor lysis syndrome (TLS) in patients with hematologic malignancies at intermediate to high TLS risk

Spina M; (...); FLORENCE Study Group

Article. 10.1093/annonc/mdv317. 2015


FOVOCIP study: a multicenter randomized trial of fosfomycin versus ciprofloxacin for febrile neutropenia in hematologic patients-efficacy and microbiologic safety

Moreno, Ainhoa Fernandez; (...); Bernal, Teresa

Article. 10.1186/s13063-023-07702-5. 2023

  • Open Access.

GENOME-WIDE ANALYSIS OF SINGLE NUCLEOTIDE POLYMORPHISM (SNPS) IN PATIENTS WITH DE NOVO ACUTE MYELOID LEUKEMIA WITH NORMAL KARYOTYPE

Ibanez, M.; (...); Cervera, J.

Meeting Abstract. 2016

  • Open Access.

Genotype and Allele Frequencies of Drug-Metabolizing Enzymes and Drug Transporter Genes Affecting Immunosuppressants in the Spanish White Population

Bosó V; (...); Aliño SF

Article. 10.1097/FTD.0b013e3182a94e65. 2014


Hazardous drugs: new challenges, new opportunities.

Valero García S; (...); Poveda Andrés JL

Article. 10.7399/fh.2016.40.2.10462. 2016

  • Open Access.

Hematologic neoplasms: interpreting lung findings in chest computed tomography.

Calvillo Batllés P; (...); Compte Torrero L

Article. 10.1016/j.rx.2015.07.003. 2015


High Delta Np73/TAp73 ratio is associated with poor prognosis in acute promyelocytic leukemia

Lucena-Araujo AR; (...); Rego EM

Article. 10.1182/blood-2015-01-623330. 2015


High-permeability region size on perfusion CT predicts hemorrhagic transformation after intravenous thrombolysis in stroke

Puig, J; (...); Castellanos, M

Article. 10.1371/journal.pone.0188238. 2017

  • Open Access.

How we prevent and treat differentiation syndrome in patients with acute promyelocytic leukemia

Sanz MA, Montesinos P

Review. 10.1182/blood-2013-10-512640. 2014


Iadademstat in combination with azacitidine in patients with newly diagnosed acute myeloid leukaemia (ALICE): an open-label, phase 2a dose-finding study.

Salamero, Olga; (...); Montesinos, Pau

Article. 10.1016/S2352-3026(24)00132-7. 2024


Impact of minimal residual disease on outcomes after umbilical cord blood transplantation for adults with Philadelphia-positive acute lymphoblastic leukaemia: an analysis on behalf of Eurocord, Cord Blood Committee and the Acute Leukaemia working party of the European group for Blood and Marrow Transplantation

Tucunduva L; (...); Rocha V

Article. 10.1111/bjh.12970. 2014


Impact of natural-killer immune reconstitution on the development of cytomegalovirus infection, non-relapse mortality, and graft versus host disease after allogeneic stem cell transplantation

Rodriguez-Veiga, R.; (...); Sanz, M. A.

Meeting Abstract. 2015


Impact of Single Nucleotide Polymorphisms (SNPs) on Immunosuppressive Therapy in Lung Transplantation

Ruiz J; (...); Aliño SF

Article. 10.3390/ijms160920168. 2015

  • Open Access.

Impact of transplant eligibility and availability of a human leukocyte antigen-identical matched related donor on outcome of older patients with acute lymphoblastic leukemia

Barba P; (...); Ribera JM

Article. 10.3109/10428194.2015.1014365. 2015


Impact of Transporter Genes Polymorphisms in Standard Induction of Acute Myeloid Leukemia

Eduardo Megias, Juan; (...); Angel Sanz, Miguel

Meeting Abstract. 2015


Impact on Outcomes of Human Leukocyte Antigen Matching by Allele-Level Typing in Adults with Acute Myeloid Leukemia Undergoing Umbilical Cord Blood Transplantation

Sanz J; (...); Sanz GF

Article. 10.1016/j.bbmt.2013.10.016. 2014


In vitro all-trans retinoic acid sensitivity of acute myeloid leukemia blasts with NUP98/RARG fusion gene

Such E; (...); Sanz MA

Letter. 10.1007/s00277-014-2073-5. 2014


INCIDENCE AND CHARACTERISTICS OF BACTERIAL INFECTIONS DURING THE THERAPY OF INDUCTION IN PATIENTS WITH MULTIPLE MYELOMA TREATED WITH NEW DRUGS. STUDY OF 67 PATIENTS FROM A SINGLE CENTRE

Martinez Garcia, M. F.; (...); Sanz Alonso, M. A.

Meeting Abstract. 2015

  • Open Access.

Incidence and Risk Factors for Development of Cardiac Toxicity in Adult Patients with Newly Diagnosed Acute Myeloid Leukemia

Boluda, Blanca; (...); Montesinos, Pau

Article. 10.3390/cancers15082267. 2023

  • Open Access.

Incidence and risk factors of post-engraftment invasive fungal disease in adult allogeneic hematopoietic stem cell transplant recipients receiving oral azoles prophylaxis

Montesinos P; (...); Sanz MA

Article. 10.1038/bmt.2015.181. 2015


Incidence, clinical and biological characteristics and outcome of secondary acute lymphoblastic leukemia after solid organ or hematologic malignancy

Kelleher, N; (...); Spanish Soc Hematology

Article. 10.3109/10428194.2015.1040013. 2016


Incidence, risk factors, and outcome of bacteremia following autologous hematopoietic stem cell transplantation in 720 adult patients

Pinana JL; (...); Sanz MA

Article. 10.1007/s00277-013-1872-4. 2014


Incompatibility of undiluted busulfan injection with a needle-free valve

Cueto-Sola, M; (...); Poveda-Andres, JL

Letter. 10.2146/ajhp140111. 2014


Influence of ABCB1 polymorphisms upon the effectiveness of standard treatment for acute myeloid leukemia: A systematic review and meta-analysis of observational studies

Megías-Vericat JE; (...); Aliño SF

Review. 10.1038/tpj.2014.80. 2015


Influence of Single Nucleotide Polymorphisms in Anthracycline Metabolism Pathway in Standard Induction of Acute Myeloid Leukemia

Eduardo Megias, Juan; (...); Angel Sanz, Miguel

Meeting Abstract. 2015


Internal tandem duplication of the FLT3 gene confers poor overall survival in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline-based chemotherapy: an International Consortium on Acute Promyelocytic Leukemia study

Lucena-Araujo AR; (...); Rego EM

Article. 10.1007/s00277-014-2142-9. 2014


International Randomized Phase III Study of Elacytarabine Versus Investigator Choice in Patients With Relapsed/Refractory Acute Myeloid Leukemia

Roboz GJ; (...); Giles FJ

Article. 10.1200/JCO.2013.52.8562. 2014


Intravenous busulfan for autologous stem cell transplantation in adult patients with acute myeloid leukemia: a survey of 952 patients on behalf of the Acute Leukemia Working Party of the European Group for Blood and Marrow Transplantation

Nagler A; (...); Mohty M

Article. 10.3324/haematol.2014.105197. 2014

  • Open Access.

Maternal and fetal outcomes in pregnant women with acute promyelocytic leukemia

Sanz MA; (...); Perales A

Article. 10.1007/s00277-015-2372-5. 2015


Meta-analysis and systematic review of the effect of the donor and recipient CYP3A5 6986A>G genotype on tacrolimus dose requirements in liver transplantation.

Rojas LE; (...); Aliño SF

Article. 10.1097/FPC.0b013e3283642fb3. 2013


Minimal residual disease evaluation by flow cytometry is a complementary tool to cytogenetics for treatment decisions in acute myeloid leukaemia

Vidriales, MB; (...); PETHEMA Programa Estudio Terapeuti

Article. 10.1016/j.leukres.2015.10.002. 2016


Myeloablative cord blood transplantation in adults with acute leukemia: comparison of two different transplant platforms.

Sanz J; (...); Brunstein C

Article. 10.1016/j.bbmt.2013.09.015. 2013


N. VICTOR JIMENEZ TORRES (1942-2015) IN MEMORIAM

Climente Martí M, Poveda Andrés JL, Culebras J

Biographical-Item. 10.3305/nh.2015.32.4.9704. 2015

  • Open Access.

One-Unit versus Two-Unit Cord-Blood Transplantation

Sanz, J, Sanz, GF, Sanz, MA

Letter. 2015


One-unit versus two-unit cord-blood transplantation.

Sanz J, Sanz GF, Sanz MA

Letter. 2015


Outcome of graft failure after allogeneic stem cell transplant: study of 89 patients

Ferrà C; (...); Ribera JM

Article. 10.3109/10428194.2014.930849. 2015


Outcome of patients with abnl(17p) acute myeloid leukemia after allogeneic hematopoietic stem cell transplantation

Middeke JM; (...); Schetelig J

Article. 10.1182/blood-2013-12-544957. 2014


Outcomes after intensive chemotherapy for secondary and myeloid-related changes acute myeloid leukemia patients aged 60 to 75 years old: a retrospective analysis from the PETHEMA registry

Martinez-Cuadron, David; (...); Montesinos, Pau

Article. 10.3324/haematol.2022.282506. 2024

  • Open Access.

Panobinostat as part of induction and maintenance for elderly patients with newly diagnosed acute myeloid leukemia: phase Ib/II panobidara study

Ocio EM; (...); PETHEMA Group

Article. 10.3324/haematol.2015.129577. 2015

  • Open Access.

Passenger lymphocyte syndrome in liver transplant recipients: a description of 12 cases

Romero S; (...); Sanz MÁ

Article. 10.2450/2015.0148-14. 2015


Pharmacological Profiles of Acute Myeloid Leukemia Treatments in Patient Samples by Automated Flow Cytometry: A Bridge to Individualized Medicine

Bennett TA; (...); Ballesteros J

Article. 10.1016/j.clml.2013.11.006. 2014


Phase II trial to assess the safety and efficacy of clofarabine in combination with low-dose cytarabine in elderly patients with acute myeloid leukemia

Martínez-Cuadrón D; (...); Sanz MA

Article. 10.1007/s00277-013-1914-y. 2014


Positive impact of ABCB1 polymorphisms in overall survival and complete remission in acute myeloid leukemia: a systematic review and meta-analysis

Megías-Vericat JE; (...); Aliño SF

Letter. 10.1038/tpj.2015.79. 2016


Prognostic Impact of Anthracycline Metabolism Gene Polymorphisms in Newly Diagnosed Acute Myeloid Leukemia Adults

Eduardo Megias, Juan; (...); Angel Sanz, Miguel

Article. 2014


Prognostic Impact of Cytarabine Pathway Gene Polymorphisms in Acute Myeloid Leukemia Adults Undergoing Induction Chemotherapy

Eduardo Megias, Juan; (...); Angel Sanz, Miguel

Article. 2014


Prognostic impact of KMT2E transcript levels on outcome of patients with acute promyelocytic leukaemia treated with all-trans retinoic acid and anthracycline-based chemotherapy: an International Consortium on Acute Promyelocytic Leukaemia study

Lucena-Araujo AR; (...); Rego EM

Article. 10.1111/bjh.12921. 2014


PROGNOSTIC IMPACT OF TRANSPORTER GENE POLYMORPHISMS IN NEWLY DIAGNOSED ACUTE MYELOID LEUKEMIA ADULTS

Megias Vericat, J. E.; (...); Sanz, M. A.

Article. 2015

  • Open Access.

Prognostic Significance of Complex Karyotype and Monosomal Karyotype in Adult Patients With Acute Lymphoblastic Leukemia Treated With Risk-Adapted Protocols

Motlló C; (...); Feliu E

Article. 10.1002/cncr.28950. 2014


Prognostic significance of copy number alterations in adolescent and adult patients with precursor B acute lymphoblastic leukemia enrolled in PETHEMA protocols

Ribera J; (...); Ribera JM

Article. 10.1002/cncr.29579. 2015


Quality of thawed plasma inactivated with methylene blue after 48-hour storage

Balaguer A; (...); Sanz MÁ

Letter. 10.1016/j.transci.2014.11.005. 2015


Rabbit antithymocyte globulin versus horse antithymocyte globulin for treatment of acquired aplastic anemia: a retrospective analysis

Vallejo C; (...); Rayón C

Article. 10.1007/s00277-015-2305-3. 2015


Reduced-Intensity Conditioning With Fludarabine and Busulfan Versus Fludarabine and Melphalan for Patients With Acute Myeloid Leukemia: A Report From the Acute Leukemia Working Party of the European Group for Blood and Marrow Transplantation

Baron F; (...); Mohty M

Article. 10.1002/cncr.29163. 2015


Results of a preoperative autologous blood donation program for patients undergoing elective major spine surgery.

Solves P; (...); Sanz MA

Article. 10.1016/j.transci.2013.06.016. 2013


RETROSPECTIVE STUDY OF AZACITIDINE IN PATIENTS OF ADVANCED AGE WITH ACUTE MYELOID LEUKEMIA (LMA). RESULTS OF THE ALMA/ PETHEMA COHORT IN COMPARISON WITH THE MRC RISK INDEX SCORE

Falantes, J.; (...); Ramos, F.

Meeting Abstract. 2015

  • Open Access.

Review of Cutaneous Graft-vs-Host Disease.

Ballester-Sánchez R; (...); Botella-Estrada R

Article. 10.1016/j.ad.2015.10.003. 2016


Risk factors for outcomes after unrelated cord blood transplantation for adults with acute lymphoblastic leukemia: a report on behalf of Eurocord and the Acute Leukemia Working Party of the European Group for Blood and Marrow Transplantation

Tucunduva L; (...); Rocha V

Article. 10.1038/bmt.2014.72. 2014


Risk of Rh (D) alloimmunisation after Rh (D) positive platelet transfusions in patients undergoing haematopoietic stem cell transplantation

Solves P; (...); Sanz MA

Letter. 10.1111/tme.12179. 2015


Single Nucleotide Polymorphisms, SNPs, Associated With the Efficacy and Security of Immunosuppressive Treatment in Heart Transplantation

Sanchez-Lazaro, I.; (...); Salvador-Sanz, A.

Article. 10.1016/j.healun.2014.01.392. 2014


Single-Nucleotide Polymorphism Array-Based Karyotyping of Acute Promyelocytic Leukemia

Gómez-Seguí I; (...); Sanz MA

Article. 10.1371/journal.pone.0100245. 2014

  • Open Access.

SNPs and taxane toxicity in breast cancer patients

Bosó V; (...); Aliño SF

Article. 10.2217/PGS.14.127. 2014


Spanish Consensus on the Prevention and Treatment of Pseudomonas aeruginosa Bronchial Infections in Cystic Fibrosis Patients

Cantón R; (...); Solé A

Article. 10.1016/j.arbres.2014.09.021. 2015


Study of the S427G polymorphism and of MYBL2 variants in patients with acute myeloid leukemia

Dolz S; (...); Barragán E

Article. 10.3109/10428194.2015.1049167. 2016


Study on the Linezolid Prescription According to the Approval of Indication in a University Hospital

Pérez-Cebrián M; (...); Llopis-González A

Article. 2015


T Cell-Depleted Related HLA-Mismatched Peripheral Blood Stem Cell Transplantation as Salvage Therapy for Graft Failure after Single Unit Unrelated Donor Umbilical Cord Blood Transplantation

Moscardó F; (...); Sanz GF

Article. 10.1016/j.bbmt.2014.03.024. 2014


Tamibarotene in patients with acute promyelocytic leukaemia relapsing after treatment with all-trans retinoic acid and arsenic trioxide

Sanford D; (...); Cortes JE

Article. 10.1111/bjh.13607. 2015


Targeting CD38 with isatuximab and a novel CD38/CD3×CD28 trispecific T-cell engager in older patients with acute myeloid leukemia.

Martín-Sánchez E; (...); Zabaleta A

Article. 10.1182/bloodadvances.2024013212. 2024

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T-cell-replete haploidentical transplantation versus autologous stem cell transplantation in adult acute leukemia: a matched pair analysis

Gorin NC; (...); Acute Leukemia Working Party of the European Society for Blood and Marrow Transp

Article. 10.3324/haematol.2014.111450. 2015

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The FLT3-like Gene Expression Signature Predicts Response to Quizartinib in Wild-Type FLT3 Acute Myeloid Leukemia: An Analysis of the Pethema Quiwi Trial

Mosquera Orgueira, Adrian; (...); Montesinos, Pau

Meeting Abstract. 10.1182/blood-2023-180482. 2023

  • Open Access.

The impact of graft-versus-host disease prophylaxis in reduced-intensity conditioning allogeneic stem cell transplant in acute myeloid leukemia: a study from the Acute Leukemia Working Party of the European Group for Blood and Marrow Transplantation

Rubio MT; (...); Mohty M

Article. 10.3324/haematol.2014.119339. 2015

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The Interaction Between Collagen-Activated Platelets and Erythrocytes Selectively Increases the Release of Subsets of Platelet alpha-Granules Containing Pro-Angiogenic Substances

Teresa Santos, Maria; (...); Valles, Juana

Meeting Abstract. 2014


THE MODULAR NETWORK STRUCTURE OF THE MUTATIONAL LANDSCAPE OF ACUTE MYELOID LEUKEMIA

Ibanez, M.; (...); Cervera, J.

Article. 2015

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The Mutational Landscape of Acute Promyelocytic Leukemia Reveals an Interacting Network of Co-Occurrences and Recurrent Mutations

Ibáñez, M; (...); Cervera, J.

Article. 10.1371/journal.pone.0148346. 2016

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The role of phototherapy in cutaneous chronic graft-vs-host disease: a retrospective study and review of the literature.

Ballester-Sánchez R; (...); Botella-Estrada R

Article. 10.1016/j.ad.2015.04.009. 2015


Trans-arterial chemoembolization with doxorubicin-eluting particles versus conventional trans-arterial chemoembolization in unresectable hepatocellular carcinoma: A study of effectiveness, safety and costs.

Megías Vericat JE; (...); Poveda Andrés JL

Article. 10.1016/j.rx.2015.01.008. 2015


Transfusion Management and Immunohematologic Complications in Liver Transplantation: Experience of a Single Institution

Solves P; (...); Sanz MÁ

Article. 10.1159/000370260. 2015


Transfusion of ABO non-identical platelets does not influence the clinical outcome of patients undergoing autologous haematopoietic stem cell transplantation

Solves P; (...); Sanz MA

Article. 10.2450/2015.0195-14. 2015


Treatment adherence and other patient-reported outcomes as cost determinants in multiple sclerosis: a review of the literature

Lizan, L; (...); Polanco, C

Review. 10.2147/PPA.S67253. 2014

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Treatment of High-Risk Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia in Adolescents and Adults According to Early Cytologic Response and Minimal Residual Disease After Consolidation Assessed by Flow Cytometry: Final Results of the PETHEMA ALL-AR-03 Trial

Ribera JM; (...); Feliu E

Article. 10.1200/JCO.2013.52.2425. 2014


Treatment of invasive fungal disease using anidulafungin alone or in combination for hematologic patients with concomitant hepatic or renal impairment

Montesinos P; (...); Sanz MÁ

Article. 10.1016/j.riam.2014.10.003. 2015


Treatment Outcomes in Unfit Patients with Newly Acute Myeloid Leukemia According to IDH1 Mutational Status: Real World Evidence from the Pethema Epidemiologic Registry

Martinez-Cuadron, David; (...); Montesinos, Pau

Meeting Abstract. 10.1182/blood-2023-189800. 2023

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Treatment patterns and outcomes in secondary acute myeloid leukemia arising after hypomethylating agents: PETHEMA registry study.

Lloret-Madrid, Pilar; (...); Montesinos, Pau

Article. 10.1002/cncr.35696. 2025


Umbilical cord blood transplantation from unrelated donors in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia

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Umbilical cord blood transplantation in adults with advanced hodgkin's disease: high incidence of post-transplant lymphoproliferative disease

Piñana JL; (...); GETH GITMO groups

Article. 10.1111/ejh.12557. 2016


VALIDATION OF A NEW MASSIVE SEQUENCING TECHNIQUE FOR MOLECULAR DIAGNOSIS OF ACUTE MYELOBLASTIC LEUKEMIA

Llop Garcia, M.; (...); Barragan Gonzalez, E.

Meeting Abstract. 2015

  • Open Access.

Validation of a Next-Generation Sequencing Panel for AML Routine Diagnosis

Alonso, Carmen M.; (...); Barragan, Eva

Article. 2015


Validation of a risk score for post-engraftment invasive fungal disease in 414 adult allogeneic hematopoietic stem cell transplant recipients

Montesinos, P.; (...); Sanz, M. A.

Meeting Abstract. 2016


WT1 isoform expression pattern in acute myeloid leukemia.

Luna I; (...); Sanz MA

Article. 10.1016/j.leukres.2013.10.009. 2013


Características Y Resultado A Largo Plazo De Pacientes Mayores Con Leucemia Promielocítica Aguda Tratados Con Esquemas Terapéuticos Basados En Atra Más Antraciclinas

Autor/es: David Martínez Cuadrón

Tesis Doctoral

Director/es: MIGUEL ÁNGEL SANZ ALONSO


Estudio De La Reconstitución Inmunológica En Pacientes Con Neoplasias Hematológicas Sometidos A Trasplante De Sangre De Cordón Umbilical

Autor/es: Lourdes Cordon

Tesis Doctoral

Director/es: MIGUEL ÁNGEL SANZ ALONSO


Estudio Del Gen Ikzf1 Y De Microdeleciones Intragénicas En La Leucemia Linfoblástica Aguda

Autor/es: Inés Gómez Seguí

Tesis Doctoral

Director/es: MIGUEL ÁNGEL SANZ ALONSO


Flt3 Y Npm1 Como Marcadores Moleculares En La Leucemia Mieloblástica Aguda. Utilidad Pronóstica Y Diagnóstica

Autor/es: Juan Carlos Pajuelo Gámez

Tesis Doctoral

Director/es: MIGUEL ÁNGEL SANZ ALONSO


Tratamiento Adaptado Al Riesgo De La Leucemia Promielocítica Aguda Con Atra Y Quimioterapia

Autor/es: Pau Montesinos

Tesis Doctoral

Director/es: MIGUEL ÁNGEL SANZ ALONSO


Valor De La Citogenética En La Leucemia Mieloblástica Aguda

Autor/es: José Vicente Cervera Zamora

Tesis Doctoral

Director/es: MIGUEL ÁNGEL SANZ ALONSO


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