Delta-like ligand 4 regulates vascular endothelial growth factor receptor 2-driven luteal angiogenesis through induction of a tip/stalk phenotype in proliferating endothelial cells.

Autores de IIS La Fe

• Carmen Maria Garcia Pascual

  Autor

• Hortensia Ferrero Chafer

  Autor

• Carlos Simon Valles

  Autor

• Antonio Pellicer Martínez

  Autor

Participantes ajenos a IIS La Fe

• Zimmermann RC
• Shawber CJ
• Kitajewski J
• Gómez R

Grupos

• Medicina Fetal y Reproductiva

Abstract

To explore whether the Dll4/Notch-1 signaling pathway modulates vascular endothelial growth factor (VEGF)-dependent luteal angiogenesis and related function, by inducing a tip/stalk phenotype in endothelial cells (ECs).

Keywords

• Corpus luteum, Dll4/Notch-1 pathway, angiogenesis, vessel functionality