Portal de investigación
Mesoporous Silica Materials as an Emerging Tool for Cancer Immunotherapy
Fecha de publicación:
Fecha Ahead of Print:
Autores de IIS La Fe
Participantes ajenos a IIS La Fe
- Escudero, Andrea
- Lucena-Sanchez, Elena
- Garcia-Fernandez, Alba
Grupos
Abstract
Cancer immunotherapy has emerged in the past decade as a promising strategy for treating many forms of cancer by stimulating the patient's immune system. Although immunotherapy has achieved some promising results in clinics, more efforts are required to improve the limitations of current treatments related to lack of effective and targeted cancer antigens delivery to immune cells, dose-limiting toxicity, and immune-mediated adverse effects, among others. In recent years, the use of nanomaterials has proven promising to enhance cancer immunotherapy efficacy and reduce side effects. Among nanomaterials, attention has been recently paid to mesoporous silica nanoparticles (MSNs) as a potential multiplatform for enhancing cancer immunotherapy by considering their unique properties, such as high porosity, and good biocompatibility, facile surface modification, and self-adjuvanticity. This review explores the role of MSN and other nano/micro-materials as an emerging tool to enhance cancer immunotherapy, and it comprehensively summarizes the different immunotherapeutic strategies addressed to date by using MSN.
© 2022 The Authors. Advanced Science published by Wiley-VCH GmbH.
Datos de la publicación
- ISSN/ISSNe:
- 2198-3844, 2198-3844
- Tipo:
- Review
- Páginas:
- -
- PubMed:
- 35866466
- Factor de Impacto:
- 3,984 SCImago ℠
- Cuartil:
- Q1 SCImago ℠
ADVANCED SCIENCE Wiley-VCH Verlag
Citas Recibidas en Web of Science: 27
Documentos
- No hay documentos
Filiaciones
Keywords
- cancer; checkpoint inhibitors; immunotherapy; mesoporous silica nanoparticles; photodynamic therapies; vaccines
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Cita
Escriche B,Escudero A,Lucena E,Sancenon F,Garcia A,Martinez R. Mesoporous Silica Materials as an Emerging Tool for Cancer Immunotherapy. Adv Sci (Weinh). 2022. 9(26):2200756. IF:15,100. (1).