Contrato i-PFIS Doctorados IIS - empresa en Ciencias y Tecnologías de la Salud.

Datos básicos

Protocolo:
IFI19/00026
EUDRACT:
NCT:
Centro:
HOSPITAL UNIVERSITARI I POLITÈCNIC LA FE
Año de incio:
2020
Año de finalización:
2023
RRHH NACIONAL Finan. Competitiva Pública 82.400,00 €

Documentos

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Participantes

Grupos

Financiadores - Promotores

INSTITUTO DE SALUD CARLOS III

Resultados del Ensayo Clínico


A gated material as immunosensor for in-tissue detection of IDH1-R132H mutation in gliomas

Pla, L; (...); Martinez-Manez, R

Article. 10.1016/j.snb.2021.130406. 2021

  • Open Access.

A glutathione disulfide-sensitive Janus nanomachine controlled by an enzymatic AND logic gate for smart delivery

Mayol, Beatriz; (...); Villalonga, Reynaldo

Article. 10.1039/d0nr08282a. 2021


A navitoclax-loaded nanodevice targeting matrix metalloproteinase-3 for the selective elimination of senescent cells.

Escriche-Navarro, Blanca; (...); Martinez-Manez, Ramon

Article. 10.1016/j.actbio.2024.01.002. 2024

  • Open Access.

A new 8-oxo-7,8-2 ' deoxyguanosine nanoporous anodic alumina aptasensor for colorectal cancer diagnosis in blood and urine

Pla, L; (...); Martinez-Manez, R

Article. 10.1039/d0nr07948k. 2021


A NIR fluorescent probe for the detection of renal damage based on overrepresentation of alanine aminopeptidase enzyme.

Dominguez, Marcia; (...); Martinez-Manez, Ramon

Article. 10.1039/d2cc05408f. 2023

  • Open Access.

A renal clearable fluorogenic probe for in vivo beta-galactosidase activity detection during aging and senolysis.

Rojas-Vazquez, Sara; (...); Martinez-Manez, Ramon

Article. 10.1038/s41467-024-44903-1. 2024

  • Open Access.

A Sensitive Nanosensor for the In Situ Detection of the Cannibal Drug

Garrido, E; (...); Martinez-Manez, R

Article. 10.1021/acssensors.0c01553. 2020


An enzyme-controlled mesoporous nanomachine for triple-responsive delivery

Mayol, Beatriz; (...); Villalonga, Reynaldo

Article. 10.1039/d2tb01069k. 2022


ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Lozano Torres, Beatriz; (...); Martínez Máñez, Ramón

Article. 10.1007/s00216-020-03111-8.. 2021


Aptamer-Capped nanoporous anodic alumina for Staphylococcus aureus detection

Pla, L; (...); Martinez-Manez, R

Article. 10.1016/j.snb.2020.128281. 2020


Correction: Protection against chemical submission: naked-eye detection of gamma-hydroxybutyric acid (GHB) in soft drinks and alcoholic beverages.

Rodriguez-Nuevalos, Silvia; (...); Martinez-Manez, Ramon

Article. 10.1039/d2cc90380f. 2022

  • Open Access.

Chemical Strategies for the Detection and Elimination of Senescent Cells.

Garcia-Fleitas, Jessie; (...); Martinez-Manez, Ramon

Article. 10.1021/acs.accounts.3c00794. 2024

  • Open Access.

Chromo-fluorogenic probes for beta-galactosidase detection

Lozano-Torres, Beatriz; (...); Martinez-Manez, Ramon

Review. 10.1007/s00216-020-03111-8. 2021

  • Open Access.

Delivery of miR-200c-3p Using Tumor-Targeted Mesoporous Silica Nanoparticles for Breast Cancer Therapy.

Garrido-Cano, Iris; (...); Eroles, Pilar

Article. 10.1021/acsami.3c07541. 2023

  • Open Access.

Development of Geometry-Controlled All-Orthogonal BODIPY Trimers for Photodynamic Therapy and Phototheragnosis.

Prieto-Castaneda, Alejandro; (...); Ortiz, Maria J.

Article. 10.1021/acs.orglett.2c01169. 2022

  • Open Access.

Electro-responsive films containing voltage responsive gated mesoporous silica nanoparticles grafted onto PEDOT-based conducting polymer

Garcia-Fernandez, A; (...); Martinez-Manez, R

Article. 10.1016/j.jconrel.2020.04.048. 2020


Enhancement of photoactivity and cellular uptake of (Bu4N)2[Mo6I8(CH3COO)6] complex by loading on porous MCM-41 support. Photodynamic studies as an anticancer agent.

de la Torre, Cristina; (...); Galindo, Francisco

Article. 10.1016/j.bioadv.2022.213057. 2022

  • Open Access.

Exploring the Synergy between Nano-Formulated Linezolid and Polymyxin B as a Gram-Negative Effective Antibiotic Delivery System Based on Mesoporous Silica Nanoparticles

Otri, Ismael; (...); Sancenon, Felix

Article. 10.3390/nano14020228. 2024

  • Open Access.

High-Capacity Mesoporous Silica Nanocarriers of siRNA for Applications in Retinal Delivery.

Ultimo, Amelia; (...); Ruiz-Hernandez, Eduardo

Article. 10.3390/ijms24032753. 2023

  • Open Access.

Lipofuscin labeling through biorthogonal strain-promoted azide-alkyne cycloaddition for the detection of senescent cells

Lozano-Torres, Beatriz; (...); Martinez-Manez, Ramon

Article. 10.1111/febs.16477. 2022

  • Open Access.

Mesoporous Silica Materials as an Emerging Tool for Cancer Immunotherapy

Escriche-Navarro, Blanca; (...); Martinez-Manez, Ramon

Review. 10.1002/advs.202200756. 2022

  • Open Access.

miR-99a-5p modulates doxorubicin resistance via the COX-2/ABCG2 axis in triple-negative breast cancer: from the discovery to in vivo studies

Garrido-Cano, Iris; (...); Eroles, Pilar

Letter. 10.1002/cac2.12352. 2022

  • Open Access.

MUC1 Aptamer-Capped Mesoporous Silica Nanoparticles for Navitoclax Resistance Overcoming in Triple-Negative Breast Cancer.

Vivo-Llorca G; (...); Martínez-Máñez R

Article. 10.1002/chem.202001579. 2020


Nanodevices for the Efficient Codelivery of CRISPR-Cas9 Editing Machinery and an Entrapped Cargo: A Proposal for Dual Anti-Inflammatory Therapy.

Garcia-Fernandez, Alba; (...); Martinez-Manez, Ramon

Article. 10.3390/pharmaceutics14071495. 2022

  • Open Access.

Nanoparticle-cell-nanoparticle communication by stigmergy to enhance poly(I:C) induced apoptosis in cancer cells

Ultimo, A; (...); Sancenon, F

Article. 10.1039/d0cc02795b. 2020

  • Open Access.

Oligonucleotide-capped nanoporous anodic alumina biosensor as diagnostic tool for rapid and accurate detection of Candida auris in clinical samples.

Pla, Luis; (...); Santiago-Felipe, Sara

Article. 10.1080/22221751.2020.1870411. 2020

  • Open Access.

Purely Covalent Molecular Cages and Containers for Guest Encapsulation.

Montà-González G; (...); Martí-Centelles V

Review. 10.1021/acs.chemrev.2c00198. 2022

  • Open Access.

Real-Time In Vivo Detection of Cellular Senescence through the Controlled Release of the NIR Fluorescent Dye Nile Blue

Lozano-Torres, B; (...); Martinez-Manez, R

Article. 10.1002/anie.202004142. 2020

  • Open Access.

ß-Galactosidase-Activatable Nile Blue-Based NIR Senoprobe for the Real-Time Detection of Cellular Senescence.

Lozano-Torres, Beatriz; (...); Martinez-Manez, Ramon

Article. 10.1021/acs.analchem.2c04766. 2022

  • Open Access.

Strip-based lateral flow-type indicator displacement assay for gamma-hydroxybutyric acid (GHB) detection in beverages

Garrido, Eva; (...); Martinez-Manez, Ramon

Article. 10.1016/j.snb.2022.133043. 2023

  • Open Access.

Synergistic antimicrobial photodynamic therapy using gated mesoporous silica nanoparticles containing curcumin and polymyxin B.

Medaglia, Serena; (...); Martinez-Manez, Ramon

Article. 10.1016/j.ijpharm.2024.123947. 2024

  • Open Access.

Targeted Delivery of The Pan-Inflammasome Inhibitor MM01 as An Alternative Approach to Acute Lung Injury Therapy.

Garcia-Fernandez, Alba; (...); Orzaez, Mar

Article. 10.1002/adhm.202301577. 2023

  • Open Access.

Campos de Estudio

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