Integrating Clinics, Laboratory, and Imaging for the Diagnosis of Common Variable Immunodeficiency-Related Granulomatous-Lymphocytic Interstitial Lung Disease.

Autores de IIS La Fe

• Marta Dafne Cabañero Navalón

  Autor

• Víctor García Bustos

  Autor

• Leonardo Fabio Forero Naranjo

  Autor

• Eduardo Jose Bättig Arriagada

  Autor

• María Nuñez Beltrán

  Autor

• Antonio José Cañada Martinez

  Autor

• Nelly Carolina Catalan Caceres

  Autor

• Manuela Esperanza Martínez Francés

  Autor

• Pedro Moral Moral

  Autor

Participantes ajenos a IIS La Fe

• Forner Giner, Maria Jose

Grupos

• Infección Grave

• Investigacion clínica en enfermedades crónicas e Infección por el VIH

• Neumología

Abstract

Granulomatous-lymphocytic interstitial lung disease (GLILD) is a distinct clinic-radio-pathological interstitial lung disease (ILD) that develops in 9% to 30% of patients with common variable immunodeficiency (CVID). Often related to extrapulmonary dysimmune disorders, it is associated with long-term lung damage and poorer clinical outcomes. The aim of this study was to explore the potential use of the integration between clinical parameters, laboratory variables, and developed CT scan scoring systems to improve the diagnostic accuracy of non-invasive tools.

Copyright © 2022 Cabanero-Navalon, Garcia-Bustos, Forero-Naranjo, Baettig-Arriagada, Núñez-Beltrán, Cañada-Martínez, Forner Giner, Catalán-Cáceres, Martínez Francés and Moral Moral.

Keywords

• CVID, GLILD, common variable immunodeficiency, diagnosis, interstitial lung disease, predictive model, scoring system, splenomegaly