Recommendations of the Spanish Working Group on Crohn's Disease and Ulcerative Colitis (GETECCU) on pouchitis in ulcerative colitis. Part 2: Treatment.

Fecha de publicación: Fecha Ahead of Print:

Autores de IIS La Fe

  • Belén Beltrán Niclós

    Autor

  • Natalia Chaparro Aguilera

    Autor

Participantes ajenos a IIS La Fe

  • Barreiro-de Acosta M
  • Marín-Jimenez I
  • Rodríguez-Lago I
  • Guarner F
  • Espín E
  • Ferrer Bradley I
  • Gutiérrez A
  • Gisbert JP

Grupos

Abstract

Pouchitis treatment is a complex entity that requires a close medical and surgical relationship. The elective treatment for acute pouchitis is antibiotics. After a first episode of pouchitis it is recommended prophylaxis therapy with a probiotic mix, nevertheless it is not clear the use of this formulation for preventing a first episode of pouchitis after surgery. First-line treatment for chronic pouchitis is an antibiotic combination. The next step in treatment should be oral budesonide. Selected cases of severe, chronic refractory pouchitis may benefit from biologic agents, and anti-TNF a should be recommended as the first option, leaving the new biologicals for multi-refractory patients. Permanent ileostomy may be an option in severe refractory cases to medical treatment.

Datos de la publicación

ISSN/ISSNe:
0210-5705, 0210-5705

Gastroenterologia y Hepatologia  ELSEVIER ESPANA SLU

Tipo:
Article
Páginas:
649-658
PubMed:
32600917
Factor de Impacto:
0,250 SCImago
Cuartil:
Q4 SCImago

Citas Recibidas en Web of Science: 12

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Keywords

  • Colitis ulcerosa, Enfermedad inflamatoria intestinal, Inflammatory bowel disease, Pouchitis, Reservoritis, Ulcerative colitis

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