Allogenicity of human cardiac stem/progenitor cells orchestrated by programmed death ligand 1.

Autors de IIS La Fe

• 

  Pilar Sepúlveda Sanchis

  Autor

Autors aliens a IIS La Fe

• Lauden L
• Boukouaci W
• Borlado LR
• López IP
• Tamouza R
• Charron D
• Al-Daccak R

Grups d'Investigació

• Regeneración y Trasplante Cardíaco

  

  Leader

  Pilar Sepúlveda Sanchis

Abstract

Transplantation of allogeneic cardiac stem/progenitor cells (CPC) in experimental myocardial infarction promoted cardiac regeneration and improved heart function. Although this has enhanced prospects of using allogeneic CPC for cardiac repair, the mechanisms regulating the behavior of these allogeneic cells, which are central to clinical applications, remain poorly understood.