Dose banding aplicado a la elaboracion de antineoplasicos: una revision narrativa de la literatura.

Autores de IIS La Fe

• Pablo Perez Huertas

  Autor

• Margarita Cueto Sola

  Autor

• Paloma Escobar Cava

  Autor

• Carmen Borrell Garcia

  Autor

• Asunción Albert Marí

  Autor

• Eduardo López Briz

  Autor

• José Luis Poveda Andrés

  Autor

Grupos

• Farmacogenética

Abstract

The dosage of antineoplastic drugs has historically been based on individualized prescription and preparation according to body surface area or patient s weight. Lack of resources and increased assistance workload in the areas where chemotherapy is made, are leading to the development of new systems to optimize the processing without reducing safety. One of the strategies that has been proposed is the elaboration by dose banding. This new approach standardizes the antineoplastic agents doses by making ranges or bands accepting a percentage of maximum variation. It aims to reduce processing time with the consequent reduction in waiting time for patients; to reduce errors in the manufacturing process and to promote the rational drug use. In conclusion, dose banding is a suitable method for optimizing the development of anticancer drugs, obtaining reductions in oncologic patients waiting time but without actually causing a favorable impact on direct or indirect costs.