Portal de investigación
High-resolution mapping of tuberculosis transmission: Whole genome sequencing and phylogenetic modelling of a cohort from Valencia Region, Spain.
Fecha de publicación:
Autores de IIS La Fe
Participantes ajenos a IIS La Fe
- Xu Y
- Cancino-Muñoz I
- Torres-Puente M
- Villamayor LM
- Borrás R
- Borrás-Máñez M
- Bosque M
- Camarena JJ
- Colomer-Roig E
- Colomina J
- Escribano I
- Esparcia-Rodríguez O
- Gimeno C
- Gimeno-Gascón A
- Gomila-Sard B
- González-Granda D
- Gonzalo-Jiménez N
- Guna-Serrano MR
- Martín-González C
- Moreno-Muñoz R
- Navarro D
- Navarro M
- Orta N
- Pérez E
- Prat J
- Rodríguez JC
- Ruiz-García MM
- Vanaclocha H
- Colijn C
- Comas I
Grupos
Abstract
Whole genome sequencing provides better delineation of transmission clusters in Mycobacterium tuberculosis than traditional methods. However, its ability to reveal individual transmission links within clusters is limited. Here, we used a 2-step approach based on Bayesian transmission reconstruction to (1) identify likely index and missing cases, (2) determine risk factors associated with transmitters, and (3) estimate when transmission happened.
Datos de la publicación
- ISSN/ISSNe:
- 1549-1277, 1549-1676
- Tipo:
- Article
- Páginas:
- -
- PubMed:
- 31671150
- Factor de Impacto:
- 5,616 SCImago ℠
- Cuartil:
- Q1 SCImago ℠
PLOS MEDICINE PUBLIC LIBRARY SCIENCE
Citas Recibidas en Web of Science: 68
Documentos
- No hay documentos
Filiaciones
Campos de Estudio
Cita
Xu Y,Cancino I,Torres M,Villamayor LM,Borrás R,Borrás M,Bosque M,Camarena JJ,Colomer E,Colomina J,Escribano I,Esparcia O,GIL A,Gimeno C,Gimeno A,Gomila B,González D,Gonzalo N,Guna MR,LÓPEZ JL,Martín C,Moreno R,Navarro D,Navarro M,Orta N,Pérez E,Prat J,Rodríguez JC,Ruiz MM,Vanaclocha H,Colijn C,Comas I. High-resolution mapping of tuberculosis transmission: Whole genome sequencing and phylogenetic modelling of a cohort from Valencia Region, Spain. PLos Med. 2019. 16. (10):e1002961. IF:10,500. (1).