Topiramate pharmacokinetics in neonates undergoing therapeutic hypothermia and proposal of an optimised dosing schedule.

Fecha de publicación: Fecha Ahead of Print:

Autores de IIS La Fe

Participantes ajenos a IIS La Fe

  • Usach I
  • Peris JE
  • Mangas-Sanjuan V

Grupos

Abstract

The adequate dosing of topiramate in neonates undergoing therapeutic hypothermia has not been established. The aim of this study was to design a dosing schedule capable of providing topiramate serum concentrations within the accepted therapeutic range.

Datos de la publicación

ISSN/ISSNe:
0803-5253, 1651-2227

ACTA PAEDIATRICA  WILEY

Tipo:
Article
Páginas:
300-308
PubMed:
31336401
Factor de Impacto:
0,772 SCImago
Cuartil:
Q2 SCImago

Citas Recibidas en Web of Science: 6

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Keywords

  • hypoxic ischaemic encephalopathy, neonates, population pharmacokinetics, therapeutic hypothermia, topiramate dosing

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