Portal de recerca
Estudio de fase 3, aleatorizado y controlado con placebo para evaluar la eficacia y la seguridad de MK-0616 para reducir las complicaciones cardiovasculares graves en participantes con riesgo cardiovascular elevado.
Dades bàsiques
- Protocol:
- MK-0616-015
- EURDRACT:
- NCT:
- Centre:
- HOSPITAL UNIVERSITARI I POLITÈCNIC LA FE
- Any inici:
- 2024
- Any de finalització:
Documents
- No hi ha documents
Participants
Grups d'Investigació
Finançadors - Promotors
Resultats de l'Assaig Clínic
[[en]]Peripheral access ultrafiltration in adults with complex congenital heart disease and refractory congestion.
Guerrero Cervera B; (...); Almenar Bonet L
Article. 10.1016/j.rec.2024.08.015. 2024
[Translated article] Knowledge of biological therapy in patients with immune-mediated diseases. BIOINFO study.
Segui-Solanes, Carlos; (...); Borras-Blasco, Joaquin
Article. 10.1016/j.farma.2024.08.002. 2024
[Translated article] New challenges in advanced therapies.
Megías-Vericat JE; (...); Poveda Andrés JL
Article. 10.1016/j.farma.2024.05.001. 2024
[Translated article] Pharmacokinetic-guided switching from standard half-life factor VIII to extended half-life pegylated factor VIII in haemophilia A therapy in clinical practice.
Chovi-Trull, Maria; (...); Andres, Jose Luis Poveda
Article. 10.1016/j.farma.2024.12.007. 2025
Ability of antigen carbohydrate 125 for diagnosis of heart failure with preserved ejection fraction
De Juan Baguda, J. Javier; (...); Delgado Jimenez, J. F.
Meeting Abstract. 2024
Acute performance of stylet driven leads for left bundle branch area pacing: A comparison with lumenless leads
Cano, Oscar; (...); Batul, Syeda Atiqa
Article. 10.1016/j.hroo.2023.11.014. 2023
Alterations in Mitochondrial Oxidative Phosphorylation System: Relationship of Complex V and Cardiac Dysfunction in Human Heart Failure
Gimenez-Escamilla, Isaac; (...); Rosello-Lleti, Esther
Article. 10.3390/antiox13030285. 2024
Analysis of complications in patients with ECMO as a bridge to transplantation since the beginning of the technique (2007-2023)
Guerrero Cervera, Borja; (...); Almenar Bonet, Luis
Meeting Abstract. 2024
Annual evolution of the prescription of drugs with prognostic implications in acute decompensated heart failure with reduced ejection fraction.
López-Vilella R; (...); Almenar Bonet L
Article. 10.1186/s12872-024-03728-y. 2024
Benefits of physical activity self-monitoring in patients with haemophilia: a prospective study with one-year follow-up.
Pérez-Alenda S; (...); Núñez-Cortés R
Article. 10.1111/hae.14988. 2024
Cardiomyopathy associated with primary carnitine deficiency in adults: lack of complete response in patients with delayed treatment initiation
Cervera, Borja Guerrero; (...); Zorio, Esther
Letter. 10.1016/j.recesp.2023.08.011. 2024
Cardiomyopathy associated with primary carnitine deficiency in adults: lack of complete response in patients with delayed treatment initiation.
Guerrero Cervera B; (...); Zorio E
Case Reports. 10.1016/j.rec.2023.08.011. 2024
Circulating long non-coding RNAs detection after heart transplantation and its accuracy in the diagnosis of acute cardiac rejection.
Pérez-Carrillo L; (...); Roselló-Lletí E
Letter. 10.1186/s40364-024-00590-0. 2024
Clinical profiling of patients admitted with acute heart failure: a comprehensive survival analysis.
Lopez-Vilella, Raquel; (...); Almenar Bonet, Luis
Article. 10.3389/fcvm.2024.1381514. 2024
Clinical, echocardiographic and analytical patterns of biomarkers in cardiac amyloidosis; a real-world analysis.
Lopez Vilella, R. Raquel; (...); Almenar Bonet, L.
Meeting Abstract. 2024
Comparative Temporal Analysis of Morbidity and Early Mortality in Heart Transplantation with Extracorporeal Membrane Oxygenation Support: Exploring Trends over Time
Lopez-Vilella, Raquel; (...); Bonet, Luis Almenar
Article. 10.3390/biomedicines12092109. 2024
Comprehensive survival analysis in acute heart failure: profiling patients through clinical examination at admission
Raquel Lopez Vilella, R.; (...); Almenar Bonet, L.
Meeting Abstract. 2024
Conduction System Pacing for Cardiac Resynchronization Therapy
Cano, Oscar; (...); Martinez-Dolz, Luis
Review. 10.3390/jcdd10110448. 2023
Cost-effectiveness and cost-utility analysis of haemate-P versus other von willebrand disease treatments in Spain.
Megias-Vericat, Juan E; (...); Yan, Songkai
Article. 10.1080/13696998.2025.2474886. 2025
Culprit-Lesion Drug-Coated-Balloon Percutaneous Coronary Intervention in Patients Presenting with ST-Elevation Myocardial Infarction (STEMI)
Sanz-Sanchez, Jorge; (...); Santos, Ignacio Amat
Article. 10.3390/jcm14030869. 2025
Development and testing of a mobile app for systematic collection of patient-reported outcomes (PROs) in patients with hemophilia.
Megias-Vericat, J E; (...); Poveda Andres, J L
Letter. 10.1016/j.thromres.2024.109122. 2024
Does fractional flow reserve impact on clinical outcomes by reducing number of stents and contrast media? Findings from a systematic review (N = 56,185) and meta-analysis.
Teira Calderón A; (...); Garcia-Garcia HM
Letter. 10.1016/j.carrev.2023.12.010. 2024
Does Fractional Flow Reserve Impact on Clinical Outcomes? Findings From a Systematic Review (n=56,185) and Meta-Analysis
Teira Calderon, A.; (...); Garcia-Garcia, H. M.
Meeting Abstract. 2024
Dynamics and prognostic role of persistent angina in chronic coronary syndrome with clinical, angiographic and stress CMR evidence of ischemia
Merenciano-Gonzalez, H.; (...); Bodi, V
Meeting Abstract. 10.1093/eurheartj/ehae666.1329. 2024
Endothelial Biomarkers Are Superior to Classic Inflammatory Biomarkers in Community-Acquired Pneumonia.
González-Jiménez P; (...); Méndez R
Article. 10.3390/biomedicines12102413. 2024
Impact on Survival of Heart and Heart-Lung Transplantation in Patients With Cyanotic and Noncyanotic Congenital Heart Diseases.
Donoso-Trenado, Victor; (...); Almenar-bonet, Luis
Article. 10.1016/j.transproceed.2024.12.005. 2024
Initial and Residual Cardiovascular Damage Remaining at Day 30 in Community-acquired Pneumonia
Ocana, R. Mendez; (...); Menendez, R.
Meeting Abstract. https://doi.org/10.1164/ajrccm-conference.2024.209.1_MeetingAbstracts.A6241. 2024
Left bundle branch pacing versus left ventricular septal pacing as a primary procedural endpoint during left bundle branch area pacing: Evaluation of two different implant strategies.
Cano, Oscar; (...); Martinez-Dolz, Luis
Article. 10.1111/jce.16128. 2023
Mental, emotional and social dimensions of quality of life and their relationship with physical and functional status in adults with haemophilia.
Rodríguez MA; (...); Chimeno-Hernández A
Article. 10.1016/j.thromres.2024.109181. 2024
New challenges of advanced therapies.
Megías-Vericat JE; (...); Poveda Andrés JL
Article. 10.1016/j.farma.2023.11.008. 2024
Novel Fibrillar and Non-Fibrillar Collagens Involved in Fibrotic Scar Formation after Myocardial Infarction
Ortega, Maria; (...); Ruiz-Sauri, Amparo
Article. 10.3390/ijms25126625. 2024
Penetrance of Dilated Cardiomyopathy in Genotype-Positive Relatives.
Cabrera-Romero E; (...); Garcia-Pavia P
Article. 10.1016/j.jacc.2024.02.036. 2024
Pharmacogenetics in Response to Biological Agents in Inflammatory Bowel Disease: A Systematic Review.
Ballesta-Lopez, Octavio; (...); Poveda-Andres, Jose Luis
Article. 10.3390/ijms26041760. 2025
Pharmacological Considerations during Percutaneous Treatment of Heart Failure.
Sorolla-Romero JA; (...); Sanz-Sanchez j
Article. 10.2174/0113816128284131240209113009. 2024
Plaque modification and impact on the microcirculation territory after drug-coated balloon angioplasty. The PLAMI study design
Romero, Jose Antonio Sorolla; (...); Sanchez, Jorge Sanz
Article. 10.24875/RECIC.M23000438. 2024
Plasma fibroblast activation protein is decreased in acute heart failure despite cardiac tissue upregulation
Delgado-Arija, Marta; (...); Rosello-Lleti, Esther
Article. 10.1186/s12967-024-04900-w. 2024
Practical Requirements for the Development of an Advanced Cardiorenal Unit
Almenar-Bonet, Luis; (...); Sanchez-Perez, Pilar
Review. 10.1159/000536104. 2024
Prognostic role of persistent angina after percutaneous revascularization in chronic coronary syndrome with altered angiography and stress CMR.
Perez-Sole, Nerea; (...); Bodi, Vicente
Article. 10.1016/j.rec.2024.09.004. 2024
Pulmonary arterial hypertension associated with pretricuspid shunts: risk profile and survival.
Calvo-Asensio, Maria; (...); Rueda Soriano, Joaquin
Article. 10.1016/j.rec.2024.04.016. 2024
Sex and clinical outcomes in new-onset heart failure.
Vicent, Lourdes; (...); Martinez-Selles, Manuel
Article. 10.1016/j.ijcard.2025.133092. 2025
Sex differences in aortic prognosis in Marfan patients, a retrospective longitudinal study from the REPAG registry
Tura, G. Teixido; (...); Cabrera, F.
Meeting Abstract. 10.1093/eurheartj/ehae666.2264. 2024
Toxic-metabolic encephalopathy induced by metronidazole and disulfiram: classics never die.
Chovi-Trull, Maria; (...); Poveda-Andres, Jose Luis
Article. 10.1136/ejhpharm-2024-004184. 2024
Usefulness of biomarkers to predict prognosis after heart transplant
Lopez-Vilella, Raquel; (...); Boneta, Luis Almenar
Article. 10.1016/j.rec.2024.04.019. 2024