Estudio aleatorizado, doble ciego, multicéntrico internacional, de fase III para evaluar la eficacia antitumoral y la seguridad de HLX10 (inyección de anticuerpos monoclonales humanizados anti-PD-1 recombinantes) o placebo, en combinación con quimioterapia (carboplatino/cisplatinoetopósido) y radioterapia concomitante en pacientes con cáncer de pulmón de células pequeñas en estadio limitado (CPCP-EL).

Dades bàsiques

Protocol:
HLX10-020-SCLC302
EURDRACT:
2022-002226-27
NCT:
Centre:
HOSPITAL UNIVERSITARI I POLITÈCNIC LA FE
Any inici:
2024
Any de finalització:
ENSAYO CLÍNICO

Documents

  • No hi ha documents

Participants

Grups d'Investigació

Finançadors - Promotors

SHANGHAI HENLIUS BIOTECH, INC.

Resultats de l'Assaig Clínic


[Translated article] Cybersecurity: a priority for pharmacy services in the age of artificial intelligence

Marin, Cayetano M. Hernandez, Monte-Boquet, Emilio, Andres, Jose Luis Poveda

Editorial Material. 10.1016/j.farma.2024.08.009. 2024

  • Open Access.

[Translated article] Good humanisation practices in the healthcare of patients with rare diseases in Pharmacy Services

Company Albir MJ, Andrés JLP, Solsona MDE

Article. 10.1016/j.farma.2023.10.004. 2024

  • Open Access.

[Translated article] New challenges in advanced therapies.

Megías-Vericat JE; (...); Poveda Andrés JL

Article. 10.1016/j.farma.2024.05.001. 2024

  • Open Access.

[Translated article] Pharmacokinetic-guided switching from standard half-life factor VIII to extended half-life pegylated factor VIII in haemophilia A therapy in clinical practice.

Chovi-Trull, Maria; (...); Andres, Jose Luis Poveda

Article. 10.1016/j.farma.2024.12.007. 2025


[Translated article] Real-world effectiveness and safety of nivolumab in patients with relapsed or refractory classical Hodgkin lymphoma.

Fernandez, Laura Lorente; (...); Andres, Jose Luis Poveda

Article. 10.1016/j.farma.2024.09.006. 2024

  • Open Access.

A Gadolinium(III) Complex Based on Pyridoxine Molecule with Single-Ion Magnet and Magnetic Resonance Imaging Properties.

Orts-Arroyo, Marta; (...); Martinez-Lillo, Jose

Article. 10.3390/ijms25042112. 2024

  • Open Access.

A Phase II Trial of Stereotactic Body Radiation Therapy and Androgen Deprivation for Oligometastases in Prostate Cancer (SBRT-SG 05).

Conde-Moreno, Antonio J; (...); Ferrer, Carlos

Article. 10.1016/j.prro.2024.04.022. 2024


A randomised trial of short- vs long-term androgen deprivation with salvage radiotherapy for biochemical failure following radical prostatectomy: URONCOR 06-24.

González-San Segundo C; (...); Couñago F

Article. 10.1111/bju.16484. 2024

  • Open Access.

A Smart Digital Health Platform to Enable Monitoring of Quality of Life and Frailty in Older Patients with Cancer: A Mixed-Methods, Feasibility Study Protocol.

Papachristou, Nikolaos; (...); Bamidis, Panagiotis D.

Article. 10.1016/j.soncn.2023.151437. 2023

  • Open Access.

Ability of antigen carbohydrate 125 for diagnosis of heart failure with preserved ejection fraction

De Juan Baguda, J. Javier; (...); Delgado Jimenez, J. F.

Meeting Abstract. 2024


Acute performance of stylet driven leads for left bundle branch area pacing: A comparison with lumenless leads

Cano, Oscar; (...); Batul, Syeda Atiqa

Article. 10.1016/j.hroo.2023.11.014. 2023

  • Open Access.

Alterations in Mitochondrial Oxidative Phosphorylation System: Relationship of Complex V and Cardiac Dysfunction in Human Heart Failure

Gimenez-Escamilla, Isaac; (...); Rosello-Lleti, Esther

Article. 10.3390/antiox13030285. 2024

  • Open Access.

Altered MicroRNA Maturation in Ischemic Hearts: Implication of Hypoxia on XPO5 and DICER1 Dysregulation and RedoximiR State.

Perez-Carrillo, Lorena; (...); Rosello-Lleti, Esther

Article. 10.3390/antiox12071337. 2023

  • Open Access.

Alveolar capillary dysplasia with misalignment of the pulmonary veins: A surgical lung biopsy and autopsy in a full-term newborn.

Rodríguez García C; (...); Mancheño Franch N

Article. 10.1016/j.patol.2024.06.005. 2024

  • Open Access.

Amivantamab plus chemotherapy with and without lazertinib in EGFR-mutant advanced NSCLC after disease progression on osimertinib: primary results from the phase III MARIPOSA-2 study.

Passaro, A; (...); Cho, B C

Article. 10.1016/j.annonc.2023.10.117. 2024

  • Open Access.

Analysis of complications in patients with ECMO as a bridge to transplantation since the beginning of the technique (2007-2023)

Guerrero Cervera, Borja; (...); Almenar Bonet, Luis

Meeting Abstract. 2024


Annual evolution of the prescription of drugs with prognostic implications in acute decompensated heart failure with reduced ejection fraction.

López-Vilella R; (...); Almenar Bonet L

Article. 10.1186/s12872-024-03728-y. 2024

  • Open Access.

Assessing the value of moderate-to-severe atopic dermatitis treatment using multi-criteria decision analysis (MCDA).

Pereyra-Rodríguez JJ; (...); Ortiz de Frutos FJ

Letter. 10.1111/jdv.19432. 2023

  • Open Access.

CA125: a new biomarker in patients with Fontan circulation (vol 76, pg 112, 2023)

Fuentes, Francisco Buendia; (...); Soriano, Joaquin Rueda

Correction. 10.1016/j.rec.2023.03.018. 2023


Capmatinib vs docetaxel as second- or third-line (2/3L) therapy in patients (pts) with METex14-mutated advanced NSCLC (aNSCLC): The GeoMETry-III trial

Vidal, O. J. Juan; (...); Wolf, J.

Meeting Abstract. 10.1016/j.annonc.2023.09.2424. 2023

  • Open Access.

Circulating long non-coding RNAs detection after heart transplantation and its accuracy in the diagnosis of acute cardiac rejection.

Pérez-Carrillo L; (...); Roselló-Lletí E

Letter. 10.1186/s40364-024-00590-0. 2024

  • Open Access.

Clinical phenotypes according to diuretic combination in acute heart failure.

Lopez-Vilella, Raquel; (...); Bonet, Luis Almenar

Article. 10.1016/j.hjc.2023.03.009. 2023

  • Open Access.

Clinical profiling of patients admitted with acute heart failure: a comprehensive survival analysis.

Lopez-Vilella, Raquel; (...); Almenar Bonet, Luis

Article. 10.3389/fcvm.2024.1381514. 2024

  • Open Access.

Clinical, echocardiographic and analytical patterns of biomarkers in cardiac amyloidosis; a real-world analysis.

Lopez Vilella, R. Raquel; (...); Almenar Bonet, L.

Meeting Abstract. 2024


Combining Serum miR-144-3p and miR-652-3p as Potential Biomarkers for the Early Diagnosis and Stratification of Acute Cellular Rejection in Heart Transplantation Patients.

Pérez-Carrillo L; (...); Roselló-Lletí E

Article. 10.1097/TP.0000000000004622. 2023

  • Open Access.

Comparative Temporal Analysis of Morbidity and Early Mortality in Heart Transplantation with Extracorporeal Membrane Oxygenation Support: Exploring Trends over Time

Lopez-Vilella, Raquel; (...); Bonet, Luis Almenar

Article. 10.3390/biomedicines12092109. 2024

  • Open Access.

Comprehensive survival analysis in acute heart failure: profiling patients through clinical examination at admission

Raquel Lopez Vilella, R.; (...); Almenar Bonet, L.

Meeting Abstract. 2024


Conduction System Pacing for Cardiac Resynchronization Therapy

Cano, Oscar; (...); Martinez-Dolz, Luis

Review. 10.3390/jcdd10110448. 2023

  • Open Access.

Consensus recommendations for the improvement of inter- and intra-centre care coordination in the management of hemophilia.

Montoro-Ronsano JB; (...); Soto-Ortega I

Article. 10.1016/j.farma.2023.01.003. 2023

  • Open Access.

Consensus recommendations for the improvement of inter- and intra-centre care coordination in the management of hemophilia.

Montoro-Ronsano, Jose Bruno; (...); Soto-Ortega, Inmaculada

Article. 10.1016/j.farma.2023.04.002. 2023


Correction to: Radiation therapy for vulvar cancer: consensus guidelines of the GINECOR working group of the Spanish Society of Radiation Oncology. Part 1: clinical recommendations.

Cordoba Largo S; (...); Sánchez Belda M

Correction. 10.1007/s12094-023-03183-9. 2023

  • Open Access.

Correction to: SEOM-GECP Clinical guidelines for diagnosis, treatment and follow-up of small-cell lung cancer (SCLC) (2022).

García-Campelo R; (...); Dómine M

Correction. 10.1007/s12094-023-03290-7. 2023

  • Open Access.

COST-EFFECTIVENESS ANALYSIS OF DIFELIKEFALIN FOR THE TREATMENT OF CHRONIC KIDNEY DISEASE ASSOCIATED-PRURITUS IN SPAIN

Sanchez-Alvarez, Emilio E.; (...); Hernaez Colque, M.

Meeting Abstract. 2024


Culprit-Lesion Drug-Coated-Balloon Percutaneous Coronary Intervention in Patients Presenting with ST-Elevation Myocardial Infarction (STEMI)

Sanz-Sanchez, Jorge; (...); Santos, Ignacio Amat

Article. 10.3390/jcm14030869. 2025

  • Open Access.

Cybersecurity, a priority for pharmacy services in the age of artificial intelligence.

Hernández Marín CM, Monte-Boquet E, Poveda Andrés JL

Editorial Material. 10.1016/j.farma.2024.08.001. 2024

  • Open Access.

Characterization of patients with advanced non-small-cell lung cancer (NSCLC) harboring KRASG12C mutation and their associated direct healthcare costs in Spanish routine clinical practice (SILK study)

Aransay, N. Reguart; (...); Vila, A. Lloansi

Meeting Abstract. 10.1016/j.annonc.2023.09.2442. 2023


Chronological and Biological Age as a Response Factor to Immune Checkpoint Inhibitors in Advanced Non-Small Cell Lung Cancer

Suay, G.; (...); Juan-Vidal, O.

Meeting Abstract. 2024


Datopotamab Deruxtecan Versus Docetaxel for Previously Treated Advanced or Metastatic Non-Small Cell Lung Cancer: The Randomized, Open-Label Phase III TROPION-Lung01 Study.

Ahn, Myung-Ju; (...); Sands, Jacob

Article. 10.1200/JCO-24-01544. 2024

  • Open Access.

Datopotamab Deruxtecan Vs Docetaxel in Patients with Non-Small Cell Lung Cancer: Final Overall Survival from TROPION-Lung01

Sands, J.; (...); Ahn, M-J

Meeting Abstract. 2024


Determining value in the treatment of activated PI3Kdelta syndrome in Spain: a multicriteria decision analysis from the perspective of key stakeholders.

Abad, Maria Reyes; (...); Gil, Alicia

Article. 10.33393/grhta.2024.3041. 2024

  • Open Access.

Determining what represents value in the treatment of prurigo nodularis and its key unmet needs in Spain through Multi-Criteria Decision Analysis

Silvestre, Juan Francisco; (...); Serra-Baldrich, Esther

Article. 10.1002/jvc2.275. 2024

  • Open Access.

Development of a predictive model for early detection of lung cancer: SREAL-eLUNG study

Vidal, O. J. Juan; (...); Martinez, B. Valdivieso

Meeting Abstract. 2023


Does fractional flow reserve impact on clinical outcomes by reducing number of stents and contrast media? Findings from a systematic review (N = 56,185) and meta-analysis.

Teira Calderón A; (...); Garcia-Garcia HM

Letter. 10.1016/j.carrev.2023.12.010. 2024

  • Open Access.

Does Fractional Flow Reserve Impact on Clinical Outcomes? Findings From a Systematic Review (n=56,185) and Meta-Analysis

Teira Calderon, A.; (...); Garcia-Garcia, H. M.

Meeting Abstract. 2024

  • Open Access.

Dynamics and prognostic role of persistent angina in chronic coronary syndrome with clinical, angiographic and stress CMR evidence of ischemia

Merenciano-Gonzalez, H.; (...); Bodi, V

Meeting Abstract. 10.1093/eurheartj/ehae666.1329. 2024

  • Open Access.

ECONOMIC BURDEN OF ADVANCED NON-SMALL-CELL LUNG CANCER (NSCLC) PATIENTS HARBORING KRASG12C MUTATION IN SPAIN

Fernandez-Barcelo, C.; (...); Sampietro-Colom, L.

Meeting Abstract. 2023


Efficacy and safety of MCLA-129, an anti-EGFR/c-MET bispecific antibody, in non-small-cell lung cancer (NSCLC) with c-METexon 14 skipping mutations (METex14).

Brandao, Mariana da Rocha Almeida; (...); Felip, Enriqueta

Meeting Abstract. 2024

  • Open Access.

Encorafenib and binimetinib followed by radiotherapy for patients with BRAFV600-mutant melanoma and brain metastases (E-BRAIN/GEM1802 phase II study).

Marquez-Rodas, Ivan; (...); Berrocal, Alfonso

Article. 10.1093/neuonc/noae116. 2024

  • Open Access.

Endothelial Biomarkers Are Superior to Classic Inflammatory Biomarkers in Community-Acquired Pneumonia.

González-Jiménez P; (...); Méndez R

Article. 10.3390/biomedicines12102413. 2024

  • Open Access.

European Society of Medical Oncology (ESMO) guidelines for oncogene-addicted metastatic non-small cell lung cancer (NSCLC): a personalized treatment for each patient.

Suay, Guillermo, Aparisi, Francisco, Juan-Vidal, Oscar

Article. 10.21037/cco-23-100. 2024


Evaluation of EMBARK criteria patients. Real-world data on prostate cancer biochemical recurrence

Centelles Hidalgo, Elena; (...); Lopez-Campos, Fernando

Meeting Abstract. 2024


Expert Consensus on the Management of Adverse Events of Lorlatinib in the Treatment of ALK+ Advanced Non-small Cell Lung Cancer.

Arriola E; (...); Felip E

Article. 10.1007/s40261-024-01379-7. 2024

  • Open Access.

FAMetA: a mass isotopologue-based tool for the comprehensive analysis of fatty acid metabolism.

Alcoriza-Balaguer MI; (...); Lahoz A

Article. 10.1093/bib/bbad064. 2023

  • Open Access.

First-line (1L) nivolumab (N) plus ipilimumab (I) plus chemotherapy (C) vs C alone in patients (pts) with metastatic NSCLC (mNSCLC) from CheckMate 9LA: 4-y clinical update and outcomes by tumor histologic subtype (THS)

Carbone, David Paul; (...); Reck, Martin

Meeting Abstract. 2023


First-line (1L) nivolumab (N) plus ipilimumab (I) plus chemotherapy (C) vs C alone in patients (pts) with metastatic NSCLC (mNSCLC) from CheckMate 9LA: 4-y clinical update and outcomes by tumor histologic subtype (THS).

Carbone, David Paul; (...); Reck, Martin

Meeting Abstract. 10.1200/JCO.2023.41.17_suppl.LBA9023. 2023


First-line Nivolumab (N) plus Ipilimumab (I) plus Chemotherapy (C) in Metastatic NSCLC (mNSCLC): CheckMate 9LA 4-Year Clinical Update

Baclin, Firas; (...); Reck, Martin

Meeting Abstract. 2024


Five-year outcomes with first-line (1L) nivolumab plus ipilimumab plus chemotherapy (N plus I plus C) vs C in patients (pts) with metastatic NSCLC (mNSCLC) in CheckMate 9LA.

Reck, Martin; (...); Paz-Ares, Luis G.

Meeting Abstract. https://doi.org/10.1200/JCO.2024.42.16_suppl.8560. 2024

  • Open Access.

Five-year outcomes with first-line nivolumab plus ipilimumab with 2 cycles of chemotherapy versus 4 cycles of chemotherapy alone in patients with metastatic non-small cell lung cancer in the randomized CheckMate 9LA trial.

Reck M; (...); Paz-Ares LG

Article. 10.1016/j.ejca.2024.114296. 2024

  • Open Access.

Four-year clinical update and treatment switching-adjusted outcomes with first-line nivolumab plus ipilimumab with chemotherapy for metastatic non-small cell lung cancer in the CheckMate 9LA randomized trial.

Carbone DP; (...); Reck M

Article. 10.1136/jitc-2023-008189. 2024

  • Open Access.

FURTHER: A global study to evaluate furmonertinib in patients with EGFR mutant NSCLC including uncommon EGFR mutations (FURMO-002)

Le, Xiuning; (...); Wang, Jie

Meeting Abstract. https://doi.org/10.1200/JCO.2024.42.16_suppl.TPS8666. 2024

  • Open Access.

FURTHER: A Global, Randomized Study of Firmonertinib at Two Dose Levels in TKI-Naive, Advanced NSCLC with EGFR PACC Mutations

Le, X.; (...); Wang, J.

Meeting Abstract. 2024


GALLANT-1: GB1211 galectin-3 (Gal-3) inhibitor plus atezolizumab (atz) for first line treatment in patients (pts) with advanced/metastatic non-small cell lung cancer (NSCLC)

Aparisi Aparisi, F. D. A.; (...); Ghiringhelli, F.

Meeting Abstract. 10.1016/j.annonc.2023.09.2491. 2023


Genetic Variants Associated with Biological Treatment Response in Inflammatory Bowel Disease: A Systematic Review.

Plaza J; (...); Moret-Tatay I

Article. 10.3390/ijms25073717. 2024

  • Open Access.

Genotypic Characteristics and Resistance Mutations in Advanced ALK plus NSCLC: The ALK-PATHFINDER Study

Lopez Castro, R.; (...); Ponce Aix, S.

Meeting Abstract. 2023


Health-Related Quality of Life (HRQoL) Outcomes with Adagrasib vs Docetaxel in KRASG12C-Mutated Advanced NSCLC in KRYSTAL-12

Felip, E.; (...); Duruisseaux, M.

Meeting Abstract. https://doi.org/10.1016/j.jtho.2024.09.056. 2024


How can artificial intelligence optimize value-based contracting?

Poveda, Jose Luis; (...); Medrano, Ignacio H.

Letter. 10.1186/s40545-022-00475-3. 2022

  • Open Access.

Immune checkpoint inhibitors as first-line treatment for brain metastases in stage IV NSCLC patients without driver mutations

Suay, Guillermo; (...); Lahoz, Agustin

Review. 10.1016/j.canlet.2024.217317. 2024

  • Open Access.

Immunogenicity of COVID-19 vaccines in lung cancer patients.

Provencio M; (...); Calvo V

Article. 10.1016/j.lungcan.2023.107323. 2023

  • Open Access.

Impact of Advanced Age on the Incidence of Major Adverse Cardiovascular Events in Patients with Type 2 Diabetes Mellitus and Stable Coronary Artery Disease in a Real-World Setting in Spain.

González-Juanatey C; (...); Savana Research Group

Article. 10.3390/jcm12165218. 2023

  • Open Access.

Impact of Molecular Testing Using Next-Generation Sequencing in the Clinical Management of Patients with Non-Small Cell Lung Cancer in a Public Healthcare Hospital.

Simarro, Javier; (...); Palanca, Sarai

Article. 10.3390/cancers15061705. 2023

  • Open Access.

Impact on Survival of Heart and Heart-Lung Transplantation in Patients With Cyanotic and Noncyanotic Congenital Heart Diseases.

Donoso-Trenado, Victor; (...); Almenar-bonet, Luis

Article. 10.1016/j.transproceed.2024.12.005. 2024


Initial and Residual Cardiovascular Damage Remaining at Day 30 in Community-acquired Pneumonia

Ocana, R. Mendez; (...); Menendez, R.

Meeting Abstract. https://doi.org/10.1164/ajrccm-conference.2024.209.1_MeetingAbstracts.A6241. 2024

  • Open Access.

Is erenumab an efficient alternative for the prevention of episodic and chronic migraine in Spain? Results of a cost-effectiveness analysis.

Pozo-Rosich P; (...); Irimia P

Article. 10.1186/s10194-024-01747-w. 2024

  • Open Access.

Is the Benefit of Treating Iron Deficiency Greater in Acute Heart Failure with Renal Dysfunction?

Lopez-Vilella, Raquel; (...); Almenar Bonet L

Article. 10.3390/life13040915. 2023

  • Open Access.

Isavuconazole Pharmacokinetics in Critically Ill Patients: Relationship with Clinical Effectiveness and Patient Safety.

Martin-Cerezuela, Maria; (...); Ramirez Galleymore, Paula

Article. 10.3390/antibiotics13080706. 2024

  • Open Access.

KRYSTAL-12: Phase 3 study of adagrasib versus docetaxel in patients with previously treated advanced/metastatic non-small cell lung cancer (NSCLC) harboring a KRASG12C mutation

Mok, Tony S. K.; (...); Barlesi, Fabrice

Meeting Abstract. 10.1200/JCO.2024.42.17_suppl.LBA8509. 2024

  • Open Access.

LATTICE radiotherapy: A one institution experience

Solero, I.; (...); Conde, A.

Meeting Abstract. 2023


Left bundle branch pacing versus left ventricular septal pacing as a primary procedural endpoint during left bundle branch area pacing: Evaluation of two different implant strategies.

Cano, Oscar; (...); Martinez-Dolz, Luis

Article. 10.1111/jce.16128. 2023


Manipulación de fármacos para su administración por gastrostomía endoscópica percutánea en pacientes con esclerosis lateral amiotrófica y nutrición enteral.

Vázquez Polo A; (...); Vázquez Costa JF

Article. 10.20960/nh.03946. 2022

  • Open Access.

Mortality after the first hospital admission for acute heart failure de novo vs. acutely decompensated heart failure with reduced ejection fraction

Lopez Vilella, R. Raquel; (...); Almenar Bonet, L.

Meeting Abstract. 2023


Mortality After the First Hospital Admission for Acute Heart Failure, De Novo Versus Acutely Decompensated Heart Failure With Reduced Ejection Fraction.

Lopez-Vilella, Raquel; (...); Almenar Bonet, Luis

Article. 10.1016/j.amjcard.2023.03.008. 2023

  • Open Access.

Multi-Institutional Analysis of Metastasis Directed Therapy with or without Androgen Deprivation Therapy in Oligometastatic Castration Sensitive Prostate Cancer.

Sutera, P.; (...); Sweeney, C.

Article. 10.1016/j.ijrobp.2023.06.1620. 2023

  • Open Access.

Multi-institutional Analysis of Metastasis-directed Therapy with or Without Androgen Deprivation Therapy in Oligometastatic Castration-sensitive Prostate Cancer.

Deek MP; (...); Sweeney C

Article. 10.1016/j.euo.2024.03.010. 2024

  • Open Access.

National Survey on the Use of Mobile Applications in Patients with Hemophilia and Other Coagulopathies

Eduardo Megias, Juan; (...); Poveda Andres, Jose Luis

Meeting Abstract. 10.1182/blood-2022-169938. 2022

  • Open Access.

New challenges of advanced therapies.

Megías-Vericat JE; (...); Poveda Andrés JL

Article. 10.1016/j.farma.2023.11.008. 2024

  • Open Access.

Node Oligorecurrence in Prostate Cancer: A Challenge.

Zapatero A; (...); Aldave D

Article. 10.3390/cancers15164159. 2023

  • Open Access.

Novel Combinations of Immunotherapies or DNA Damage Repair Inhibitors in Platinum-Refractory Extensive-Stage Small-Cell Lung Cancer: The Phase II BALTIC Study.

Reinmuth, Niels; (...); Bondarenko, Igor

Article. 10.1158/1078-0432.CCR-24-0013. 2024

  • Open Access.

Novel Fibrillar and Non-Fibrillar Collagens Involved in Fibrotic Scar Formation after Myocardial Infarction

Ortega, Maria; (...); Ruiz-Sauri, Amparo

Article. 10.3390/ijms25126625. 2024

  • Open Access.

Observational study to evaluate discontinuation of monotherapy with cobicistat-boosted darunavir in patients with human immunodeficiency virus

Solana-Altabella, Antonio; (...); Poveda-Andres, Jose Luis

Article. 10.1097/MD.0000000000032208. 2022

  • Open Access.

ODs with a positive TPR conclusion, not subject to a conditional approval, and approved without requering a pass would be more likely to be reimbursed in Spain.

Poveda JL; (...); Badia X

Article. 10.1186/s13023-022-02610-4. 2023

  • Open Access.

Omics-Based Approaches for the Characterization of Pompe Disease Metabolic Phenotypes

Gomez-Cebrian, Nuria; (...); Puchades-Carrasco, Leonor

Review. 10.3390/biology12091159. 2023

  • Open Access.

OPTIMIZING MANAGEMENT AND OUTCOMES OF ACTIVATED PHOSPHOINOSITIDE 3-KINASE DELTA SYNDROME (APDS) IN SPAIN: BEWAYAPDS PROJECT

Flores-Moreno, S.; (...); Gil, A.

Meeting Abstract. 2024


Oxygen therapy at 1.4 atmospheres in radiation-induced cystitis and proctitis

Prato Carreno, O. A.; (...); Conde Moreno, A. J.

Meeting Abstract. 2023


PEACE V-Salvage Treatment of oligorecurrent nodal prostate cancer metastases (STORM): 24-months toxicity results of a randomized phase II trial

Zilli, T.; (...); Ost, P.

Meeting Abstract. 2024

  • Open Access.

PEACE V-Salvage Treatment of OligoRecurrent nodal prostate cancer Metastases (STORM): Acute Toxicity of a Randomized Phase 2 Trial.

Ost, Piet; (...); Zilli, Thomas

Article. 10.1016/j.euo.2023.09.007. 2023


Penetrance of Dilated Cardiomyopathy in Genotype-Positive Relatives.

Cabrera-Romero E; (...); Garcia-Pavia P

Article. 10.1016/j.jacc.2024.02.036. 2024

  • Open Access.

Pharmacogenetics in Response to Biological Agents in Inflammatory Bowel Disease: A Systematic Review.

Ballesta-Lopez, Octavio; (...); Poveda-Andres, Jose Luis

Article. 10.3390/ijms26041760. 2025

  • Open Access.

Pharmacological Considerations during Percutaneous Treatment of Heart Failure.

Sorolla-Romero JA; (...); Sanz-Sanchez j

Article. 10.2174/0113816128284131240209113009. 2024


Phase II Trial of Atezolizumab Combined With Carboplatin and Pemetrexed for Patients With Advanced Nonsquamous Non-Small-Cell Lung Cancer With Untreated Brain Metastases (Atezo-Brain, GECP17/05).

Nadal E; (...); Bruna J

Article. 10.1200/JCO.22.02561. 2023

  • Open Access.

Plain language summary: tarlatamab for patients with previously treated small cell lung cancer.

Ahn, Myung-Ju; (...); Paz-Ares, Luis

Article. 10.1080/14796694.2024.2402152. 2024

  • Open Access.

Plaque modification and impact on the microcirculation territory after drug-coated balloon angioplasty. The PLAMI study design

Romero, Jose Antonio Sorolla; (...); Sanchez, Jorge Sanz

Article. 10.24875/RECIC.M23000438. 2024

  • Open Access.

Plasma fibroblast activation protein is decreased in acute heart failure despite cardiac tissue upregulation

Delgado-Arija, Marta; (...); Rosello-Lleti, Esther

Article. 10.1186/s12967-024-04900-w. 2024

  • Open Access.

Practical Requirements for the Development of an Advanced Cardiorenal Unit

Almenar-Bonet, Luis; (...); Sanchez-Perez, Pilar

Review. 10.1159/000536104. 2024

  • Open Access.

Presence of good humanization practices in the healthcare of patients with rare diseases in Pharmacy Services

Company Albir MJ, Poveda Andrés JL, Edo Solsona MD

Article. 10.1016/j.farma.2023.06.0131130. 2024

  • Open Access.

Prognostic role of persistent angina after percutaneous revascularization in chronic coronary syndrome with altered angiography and stress CMR.

Perez-Sole, Nerea; (...); Bodi, Vicente

Article. 10.1016/j.rec.2024.09.004. 2024

  • Open Access.

Pulmonary arterial hypertension associated with pretricuspid shunts: risk profile and survival.

Calvo-Asensio, Maria; (...); Rueda Soriano, Joaquin

Article. 10.1016/j.rec.2024.04.016. 2024

  • Open Access.

Radiation therapy for vulvar cancer: consensus guidelines of the GINECOR working group of the Spanish Society of Radiation Oncology. Part 1: clinical recommendations.

Cordoba Largo S; (...); Sánchez Belda M

Article. 10.1007/s12094-023-03095-8. 2023


Radiation therapy for vulvar cancer: consensus technical guidelines of the GINECOR working group of the Spanish Society of Radiation Oncology. Part 2: radiotherapy recommendations.

Cordoba Largo, Sofia; (...); Sanchez Belda M

Article. 10.1007/s12094-023-03101-z. 2023


Real-world evidence analysis of early-stage prostate cancer using natural language processing

Juarez, Alvaro; (...); Alcaraz, Antonio

Meeting Abstract. 2023


Real-world outcomes of first-line pembrolizumab (Pem) for metastatic non-small cell lung cancer (mNSCLC) with >= 50% expression of programmed cell death-ligand 1 (PD-L1): A multicentre retrospective study

Perea, J.; (...); Gaudens, P. Capdevila

Meeting Abstract. 2023


Re-irradiation in NSCLC High-dose RT: Control, Survival and Toxicity

Germain, J.; (...); Conde, A.

Meeting Abstract. 2023


RET Fusion Testing in Patients With NSCLC: The RETING Study.

Conde, Esther; (...); Lopez-Rios, Fernando

Article. 10.1016/j.jtocrr.2024.100653. 2024

  • Open Access.

RT after Encorafenib and Binimetinib on BRAF mutated melanoma brain metastases. GEM1802-Phase II

Alvarez, A.; (...); Marquez Rodas, I.

Meeting Abstract. 2023


Sacituzumab govitecan (SG) vs docetaxel (doc) in patients (pts) with metastatic non-small cell lung cancer (mNSCLC) previously treated with platinum (PT)-based chemotherapy (chemo) and PD(L)-1inhibitors (IO): Primary results from the phase 3 EVOKE-01 study.

Paz-Ares, Luis G.; (...); Garassino, Marina Chiara

Meeting Abstract. 10.1200/JCO.2024.42.17_suppl.LBA8500. 2024

  • Open Access.

Sacituzumab Govitecan Versus Docetaxel for Previously Treated Advanced or Metastatic Non-Small Cell Lung Cancer: The Randomized, Open-Label Phase III EVOKE-01 Study.

Paz-Ares, Luis G.; (...); Garassino, Marina Chiara

Article. 10.1200/JCO.24.00733. 2024

  • Open Access.

Sacituzumab Govitecan vs Docetaxel in Patients with mNSCLC Non-responsive to Last Anti-PD-(L)1containing Regimen: EVOKE-01

Garassino, M. C.; (...); Paz-Ares, L. G.

Meeting Abstract. 2024

  • Open Access.

Salvage Treatment of OligoRecurrent nodal prostate cancer Metastases (STORM)

Ost, Piet; (...); Moon, Daniel

Meeting Abstract. 2024


SEOM-GECP Clinical guidelines for diagnosis, treatment and follow-up of small-cell lung cancer (SCLC) (2022).

Garcia-Campelo, Rosario; (...); Domine, Manuel

Article. 10.1007/s12094-023-03216-3. 2023

  • Open Access.

Sex and clinical outcomes in new-onset heart failure.

Vicent, Lourdes; (...); Martinez-Selles, Manuel

Article. 10.1016/j.ijcard.2025.133092. 2025


Sex Differences in the Efficacy of Immune Checkpoint Inhibitors in Neoadjuvant Therapy of Non-Small Cell Lung Cancer: A Meta-Analysis

Suay, Guillermo; (...); Juan-Vidal, Oscar

Review. 10.3390/cancers15184433. 2023

  • Open Access.

Spatially Preserved Multi-Region Transcriptomic Subtyping and Biomarkers of Chemoimmunotherapy Outcome in Extensive-Stage Small Cell Lung Cancer.

Peressini M; (...); Zugazagoitia J

Article. 10.1158/1078-0432.CCR-24-0104. 2024


Survival outcomes in ALK-positive NSCLC patients (p) treated 1st line brigatinib and impact of the ALK fusion variant

Provencio-Pulla, Mariano; (...); Romero, Atocha

Meeting Abstract. 2023


Tarlatamab for Patients with Previously Treated Small-Cell Lung Cancer.

Ahn MJ; (...); Paz-Ares L

Article. 10.1056/NEJMoa2307980. 2023

  • Open Access.

The association of salivary caffeine levels with serum concentrations in premature infants with apnea of prematurity

Garcia-Robles, Ana; (...); Saenz Gonzalez, Pilar

Article. 10.1007/s00431-022-04628-z. 2022


The S-REAL study: Spanish real-world data on unresectable stage III NSCLC patients treated with durvalumab after chemoradiotherapy.

Gomez Rueda, Ana; (...); Garrido, Pilar

Article. 10.1007/s12094-024-03404-9. 2024


The value of the reflective discussion in decision-making using multi-criteria decision analysis (MCDA): an example of determining the value contribution of tabelecleucel for the treatment of the Epstein Barr virus-positive post-transplant lymphoproliferative disease (EBV+ PTLD).

Badia, Xavier; (...); Valles, Joan-Antoni

Article. 10.1186/s13023-024-03324-5. 2024

  • Open Access.

Therapeutic approach in heart failure with poor diuretic response. Peripheral ultrafiltration vs. conventional treatment

Lopez-Vilella, R.; (...); Almenar Bonet, L.

Meeting Abstract. 2023


Therapeutic approach in heart failure with poor diuretic response: peripheral ultrafiltration vs. conventional treatment.

López-Vilella R; (...); Almenar Bonet L

Article. 10.1002/ehf2.14386. 2023

  • Open Access.

Toxic-metabolic encephalopathy induced by metronidazole and disulfiram: classics never die.

Chovi-Trull, Maria; (...); Poveda-Andres, Jose Luis

Article. 10.1136/ejhpharm-2024-004184. 2024


Usefulness of biomarkers to predict prognosis after heart transplant

Lopez-Vilella, Raquel; (...); Boneta, Luis Almenar

Article. 10.1016/j.rec.2024.04.019. 2024

  • Open Access.

VALUE CRITERIA FOR OUTCOMES BASED MANAGED ENTRY AGREEMENT OF CAR-T IN RELAPSED OR REFRACTORY MULTIPLE MYELOMA (RRMM) THROUGH MCDA

Poveda, J. L.; (...); Lizan, L.

Meeting Abstract. 2023


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