ENDOAGE: Un reloj molecular de envejecimiento endometrial como herramienta pronóstica para mejorar los tratamientos de reproducción asistida

Datos básicos

Protocolo:
PI23/00806
EUDRACT:
NCT:
Centro:
Año de incio:
2024
Año de finalización:
2026
PI BIOMÉDICA NACIONAL Finan. Competitiva Pública 156.250,00 €

Documentos

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Participantes

Grupos

Financiadores - Promotores

INSTITUTO DE SALUD CARLOS III

Resultados del Ensayo Clínico


A retrospective analysis shows a high effect in reproductive outcomes as age increases associated to endometrial factor in IVF advanced maternal age (AMA) patients

Sebastian-Leon, P.; (...); Diaz-Gimeno, P.

Meeting Abstract. https://doi.org/10.1093/humrep/deae108.751. 2024

  • Open Access.

Age-related uterine changes and its association with poor reproductive outcomes: a systematic review and meta-analysis

Marti-Garcia, Diana; (...); Diaz-Gimeno, Patricia

Review. 10.1186/s12958-024-01323-6. 2024

  • Open Access.

Altered endometrial receptivity: walking across the long path of precision medicine.

Diaz-Gimeno, Patricia, Sebastian-Leon, Patricia, Pellicer, Antonio

Letter. 10.1016/j.fertnstert.2024.06.010. 2024


Associations between Essential Trace Elements in Women's Biofluids and IVF Outcomes in Euploid Single Embryo Transfer Cycles

Gonzalez-Martin, Roberto; (...); Dominguez, Francisco

Meeting Abstract. 2024


Associations between Non-Essential Trace Elements in Women's Biofluids and IVF Outcomes in Euploid Single-Embryo Transfer Cycles.

Gonzalez-Martin, Roberto; (...); Dominguez, Francisco

Article. 10.3390/jox14030062. 2024

  • Open Access.

Biotechnological progresses in modelling the human endometrium: the evolution of current in vitro techniques and emerging trends.

Agustina-Hernandez, Marcos; (...); Cervello, Irene

Article. 10.3389/fbioe.2024.1495338. 2024

  • Open Access.

Corticosteroids, androgens, progestogens and oestrogens in the endometrial microenvironment, and their association with endometrial progression and function

Marti-Garcia, Diana; (...); Diaz-Gimeno, Patricia

Article. 10.1016/j.rbmo.2024.104377. 2024


Effects of In Vitro Culture Systems with Fallopian Tube Extracellular Matrix on Rabbit Embryo Gene Expression.

Frances-Herrero, Emilio; (...); Cervello, Irene

Meeting Abstract. 2024


EPITHELIAL-TO-MESENCHYMAL TRANSITION INDUCTION BY HUMAN UMBILICAL CORD PLATELET-RICH PLASMA IN HUMAN ENDOMETRIAL ORGANOIDS: DIFFERENTIATION STATE MATTERS

Agustina-Hernandez, Marcos; (...); Cervello, Irene

Meeting Abstract. 10.1016/j.fertnstert.2024.07.263. 2024

  • Open Access.

Growth Factor-Enriched Xenogeneic Ovarian ECM Hydrogels: A Promising Treatment for Premature Ovarian Failure.

Frances-Herrero, Emilio; (...); Cervello, Irene

Meeting Abstract. 2024


Higher Concentrations of Essential Trace Elements in Women Undergoing IVF May Be Associated with Poor Reproductive Outcomes Following Single Euploid Embryo Transfer.

Gonzalez-Martin, Roberto; (...); Dominguez, Francisco

Article. 10.3390/cells13100839. 2024

  • Open Access.

Human endometrial organoids embedded in hybrid endometrial-derived hydrogels as a biocompatible treatment for endometrial pathologies in preclinical models

Gomez-Alvarez, M.; (...); Cervello, I.

Meeting Abstract. https://doi.org/10.1093/humrep/deae108.1104. 2024

  • Open Access.

Impact of prolonged embryo storage on reproductive and neonatal outcomes: a systematic review and meta-analysis.

Zolfaroli I; (...); Monzó Miralles A

Article. 10.1007/s10815-024-03283-7. 2024


Oocyte Maturity, Embryology Outcomes and miRNA Signature of Different Size Follicles from Poor Responder Patients.

Yague-Serrano, Roberto; (...); Dominguez, Francisco

Meeting Abstract. 2024


Oviductal extracellular matrix hydrogels enhance in vitro culture of rabbit embryos and reduce deficiencies during assisted reproductive technologies

Frances-Herrero, Emilio; (...); Cervello, Irene

Article. 10.1038/s41598-024-77583-4. 2024

  • Open Access.

Predicting risk of endometrial failure: a biomarker signature that identifies a novel disruption independent of endometrial timing in patients undergoing hormonal replacement cycles.

Diaz-Gimeno P; (...); Pellicer A

Article. 10.1016/j.fertnstert.2024.03.015. 2024


Role of Endometrial Extracellular Vesicles miRNAs as Potential Autocrine Regulators of Gene Expression During Embryo Implantation Process in Adenomyosis.

Juarez-Barber, Elena; (...); Ferrero, Hortensia

Meeting Abstract. 2024


State-Trait Anxiety Inventory (STAI) punctuations as a non-invasive method for evaluating endometrial prognosis associated with cortisol and estradiol endometrial levels in IVF patients

Marti-Garcia, D.; (...); Diaz-Gimeno, P.

Meeting Abstract. https://doi.org/10.1093/humrep/deae108.817. 2024

  • Open Access.

Telomere length of white blood cells is a non-invasive marker of reproductive aging in women

Molina, E. E. Lara; (...); Diaz-Gimeno, P.

Meeting Abstract. https://doi.org/10.1093/humrep/deae108.1035. 2024

  • Open Access.

Transcriptome analysis of adenomyosis eutopic endometrium reveals molecular mechanisms involved in adenomyosis-related implantation failure and pregnancy disorders.

Juarez-Barber, Elena; (...); Ferrero, Hortensia

Article. 10.1186/s12958-023-01182-7. 2024

  • Open Access.

Underlying molecular mechanisms of Polycystic Ovary Syndrome and Morphology: focusing on the ovary

Ramirez Martin, N.; (...); HERRAIZ, S.

Meeting Abstract. https://doi.org/10.1093/humrep/deae108.936. 2024

  • Open Access.

UNVEILING ENDOMETRIOSIS: TRANSCRIPTOMIC PROFILING REVEALS MOLECULAR DYSREGULATION IN GESTATIONAL ENDOMETRIAL ORGANOIDS.

Bas-Rivas, Alba; (...); Ferrero, Hortensia

Meeting Abstract. 10.1016/j.fertnstert.2024.07.589. 2024

  • Open Access.

VMAP: Vaginal Microbiome Atlas during Pregnancy

Parraga-Leo, Antonio; (...); Sirota, Marina

Article. 10.1093/jamiaopen/ooae099. 2024

  • Open Access.

Whole-exome sequencing and Drosophila modelling reveal mutated genes and pathways contributing to human ovarian failure

Henarejos-Castillo, Ismael; (...); Diaz-Gimeno, Patricia

Article. 10.1186/s12958-024-01325-4. 2024

  • Open Access.

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