Engineering the human ovary: decellularized ovarian hydrogels for in vitro follicle culture.

Datos básicos

Código:
2207-FIVI-090-IC
Protocolo:
2207-FIVI-090-IC
EUDRACT:
NCT:
Centro:
HOSPITAL UNIVERSITARI I POLITÈCNIC LA FE
Dotación:
Año de incio:
2023
Año de finalización:
PI BIOMÉDICA

Documentos

  • No hay documentos

Participantes

Grupos

Financiadores - Promotores

FUNDACIÓN IVI

Resultados del Ensayo Clínico


A biomechanical assessment of tissue-engineered polymer neo-uteri after orthotopic implantation.

Nordberg RC; (...); Loboa EG

Article. 10.1016/j.xfss.2023.12.005. 2023


Addressing Key Questions in Organoid Models: Who, Where, How, and Why?

Gomez-Alvarez, Maria; (...); Cervello, Irene

Article. 10.3390/ijms242116014. 2023


Advances of xenogeneic ovarian extracellular matrix hydrogels for in vitro follicle development and oocyte maturation.

Frances-Herrero, Emilio; (...); Cervello, Irene

Article. 10.1016/j.bioadv.2023.213480. 2023


Biotechnological progresses in modelling the human endometrium: the evolution of current in vitro techniques and emerging trends.

Agustina-Hernandez, Marcos; (...); Cervello, Irene

Article. 10.3389/fbioe.2024.1495338. 2024

  • Open Access.

Effects of In Vitro Culture Systems with Fallopian Tube Extracellular Matrix on Rabbit Embryo Gene Expression.

Frances-Herrero, Emilio; (...); Cervello, Irene

Meeting Abstract. 2024


Endometrial Extracellular Matrix Hydrogel Alleviates Epithelial-toMesenchymal Transition Triggered by Human Umbilical Cord PlateletRich Plasma in Human Endometrial Organoids.

Rodriguez-Eguren, Adolfo; (...); Cervello, Irene

Meeting Abstract. 2024


Endometrial extracellular vesicles regulate processes related to embryo development and implantation in human blastocysts

Segura-Benitez, Marina; (...); Ferrero, Hortensia

Article. 10.1093/humrep/deae256. 2024


EPITHELIAL-TO-MESENCHYMAL TRANSITION INDUCTION BY HUMAN UMBILICAL CORD PLATELET-RICH PLASMA IN HUMAN ENDOMETRIAL ORGANOIDS: DIFFERENTIATION STATE MATTERS

Agustina-Hernandez, Marcos; (...); Cervello, Irene

Meeting Abstract. 10.1016/j.fertnstert.2024.07.263. 2024

  • Open Access.

Evolution of biotechnological advances and regenerative therapies for endometrial disorders: a systematic review.

Rodriguez-Eguren, Adolfo; (...); Cervello, Irene

Article. 10.1093/humupd/dmae013. 2024


GLOBAL DELETION OF MITOCHONDRIAL PINK1 GENE INDUCES LOSS OF FOLLICULAR RESERVE AND PRODUCES FEMALE INFERTILITY

Rodriguez Eguren, Adolfo; (...); Seli, Emre

Meeting Abstract. 2023


Growth Factor-Enriched Xenogeneic Ovarian ECM Hydrogels: A Promising Treatment for Premature Ovarian Failure.

Frances-Herrero, Emilio; (...); Cervello, Irene

Meeting Abstract. 2024


Growth factor-loaded ovarian extracellular matrix hydrogels promote in vivo ovarian niche regeneration and enhance fertility in premature ovarian insufficiency preclinical models.

Frances-Herrero, Emilio; (...); Cervello, Irene

Article. 10.1016/j.actbio.2024.07.056. 2024


Human blastocysts uptake extracellular vesicles secreted by endometrial cells containing miRNAs related to implantation.

Segura-Benítez M; (...); Ferrero H

Article. 10.1093/humrep/dead138. 2023


Human endometrial organoids embedded in hybrid endometrial-derived hydrogels as a biocompatible treatment for endometrial pathologies in preclinical models

Gomez-Alvarez, M.; (...); Cervello, I.

Meeting Abstract. https://doi.org/10.1093/humrep/deae108.1104. 2024

  • Open Access.

Human Umbilical Cord Platelet-Rich Plasma: Metabolomic, Proteomic, and Wound Healing Studies in Endometrial Stem Cells.

Bueno-Fernandez, Clara; (...); Cervello, Irene

Meeting Abstract. 2024


Hybrid Endometrial-Derived Hydrogels: Human Organoid Culture Models and In Vivo Perspectives.

Gomez-alvarez, Maria; (...); Cervello, Irene

Article. 10.1002/adhm.202303838. 2023


Impact of prolonged embryo storage on reproductive and neonatal outcomes: a systematic review and meta-analysis.

Zolfaroli I; (...); Monzó Miralles A

Article. 10.1007/s10815-024-03283-7. 2024


Metformin Treatment Decreases Clinical Miscarriage and Improves Live Birth Rates in Infertile Patients with Insulin Resistance.

Belen Albert, Ana; (...); Ferrero, Hortensia

Meeting Abstract. 2024


MITOPHAGY-REGULATING GENE PARKIN IS REQUIRED FOR FEMALE FERTILITY

Eguren, Adolfo Rodriguez; (...); Seli, Emre

Meeting Abstract. 2023


Oviductal extracellular matrix hydrogels enhance in vitro culture of rabbit embryos and reduce deficiencies during assisted reproductive technologies

Frances-Herrero, Emilio; (...); Cervello, Irene

Article. 10.1038/s41598-024-77583-4. 2024

  • Open Access.

Role of Endometrial Extracellular Vesicles miRNAs as Potential Autocrine Regulators of Gene Expression During Embryo Implantation Process in Adenomyosis.

Juarez-Barber, Elena; (...); Ferrero, Hortensia

Meeting Abstract. 2024


Standard-dose Vitamin D supplementation as an effective and safe non-hormonal treatment for the prevention of uterine fibroid growth in reproductive-age women: A pilot study

Orive, A.; (...); Ferrero, H.

Meeting Abstract. 2023


Transcriptome analysis of adenomyosis eutopic endometrium reveals molecular mechanisms involved in adenomyosis-related implantation failure and pregnancy disorders.

Juarez-Barber, Elena; (...); Ferrero, Hortensia

Article. 10.1186/s12958-023-01182-7. 2024


Transcriptomic analysis reveals deregulated molecular mechanisms related to miscarriage, preeclampsia, and pregnancy complications during gestational endometrial phase in adenomyosis

Juarez-Barber, E.; (...); Ferrero, H.

Meeting Abstract. 2023


Underlying mechanisms in clinical manifestations of polycystic ovarian morphology (PCOM) and PCOS women

Ramirez Martin, N.; (...); HERRAIZ, S.

Meeting Abstract. 2023


Underlying molecular mechanisms of Polycystic Ovary Syndrome and Morphology: focusing on the ovary

Ramirez Martin, N.; (...); HERRAIZ, S.

Meeting Abstract. https://doi.org/10.1093/humrep/deae108.936. 2024

  • Open Access.

UNVEILING ENDOMETRIOSIS: TRANSCRIPTOMIC PROFILING REVEALS MOLECULAR DYSREGULATION IN GESTATIONAL ENDOMETRIAL ORGANOIDS.

Bas-Rivas, Alba; (...); Ferrero, Hortensia

Meeting Abstract. 10.1016/j.fertnstert.2024.07.589. 2024

  • Open Access.

Uterine Repair Mechanisms Are Potentiated by Mesenchymal Stem Cells and Decellularized Tissue Grafts Through Elevated Vegf, Cd44, and Itgb1 Gene Expression

Bandstein, Sara; (...); Hellstrom, Mats

Article. 10.3390/bioengineering11121268. 2024

  • Open Access.

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