PHAGTHER. Utilización de bacteriófagos para el tratamiento de infecciones multirresistentes asociadas con la asistencia sanitaria.

Dades bàsiques

Protocol:
CIAICO/2021/306
EURDRACT:
NCT:
Centre:
HOSPITAL UNIVERSITARI I POLITÈCNIC LA FE
Any inici:
2022
Any de finalització:
2024
PI BIOMÉDICA AUTONÓMICO Finan. Competitiva Pública 90.000,00 €

Documents

  • No hi ha documents

Participants

Grups d'Investigació

Finançadors - Promotors

CONSELLERIA DE INNOVACIÓN, UNIVERSIDADES, CIENCIA Y SOCIEDAD DIGITAL
MARÍA ÁNGELES TORMO MAS

Resultats de l'Assaig Clínic


Candida spp. in Cetaceans: Neglected Emerging Challenges in Marine Ecosystems

Garcia-Bustos, Victor; (...); Acosta-Hernandez, Begona

Review. 10.3390/microorganisms12061128. 2024

  • Open Access.

A Cutting-Edge Bioinformatics Tool for Neoantigen Identification in Unpaired RNA-Seq Samples of AML

Perez Miguez, Carlos; (...); Montesinos, Pau

Meeting Abstract. 10.1182/blood-2024-201407. 2024


Anti-endotoxin antibodies consumption in cardiovascular collapse: Pathophysiological concerns.

Villarreal, E.; (...); Vila, J.

Article. 10.1016/j.medine.2022.04.019. 2022


Best practices during COVID-19 pandemic in solid organ transplant programs in Spain.

Pascual, Julio; (...); Delgado, Juan F.

Article. 10.1016/j.trre.2023.100749. 2023

  • Open Access.

Circulating extracellular vesicles in sera of chronic patients as a method for determining active parasitism in Chagas disease

Lozano, Noelia; (...); Osuna, Antonio

Article. 10.1371/journal.pntd.0012356. 2024

  • Open Access.

Climate change, animals, and Candida auris: insights into the ecological niche of a new species from a one health approach.

Garcia-Bustos, Victor; (...); Peman, Javier

Article. 10.1016/j.cmi.2023.03.016. 2023

  • Open Access.

Clonal Evolution Analysis Using Next Generation Sequencing (NGS) Panel in a Cohort of 3,025 Patients With Acute Myeloid Leukemia (AML)

Colmenares, Rafael; (...); Montesinos, Pau

Meeting Abstract. 2023


CMV REACTIVATIONS IN ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANT FROM HLA-MATCHED AND HAPLOIDENTICAL DONORS WITH POST-TRANSPLANT CYCLOPHOSPHAMIDE.

Chorão P; (...); Sanz J

Article. 10.1016/j.jtct.2024.01.082. 2024

  • Open Access.

Comparison of the 2022 and 2017 European LeukemiaNet risk classifications in a real-life cohort of the PETHEMA group

Sargas, Claudia; (...); Montesinos, Pau

Article. 10.1038/s41408-023-00835-5. 2023

  • Open Access.

Conventional PCR Versus Next Generation Sequencing for Diagnosis of FLT3, IDH and NPM1 Mutations in Acute Myeloid Leukemia: Interim Analysis of the PCR-LMA Protocol of the Pethema Group

Boluda, Blanca; (...); Montesinos, Pau

Meeting Abstract. 10.1182/blood-2022-160136. 2022

  • Open Access.

Corrigendum to "Safety and effectiveness of isavuconazole in real-life non-neu tropenic patients" [International Journal of Infectious Diseases 144 (2024) 107070].

Monzó-Gallo P; (...); Garcia-Vidal C

Correction. 10.1016/j.ijid.2024.107188. 2024

  • Open Access.

Critical appraisal beyond clinical guidelines for intraabdominal candidiasis.

Maseda, Emilio; (...); Rodriguez, Alejandro

Article. 10.1186/s13054-023-04673-6. 2023

  • Open Access.

Cystic Fibrosis: From Salty Malediction to Possible Cure.

Sole, Amparo, Davies, Jane C., Quintana-Gallego, Esther

Editorial Material. 10.1016/j.arbres.2023.10.007. 2023


Cytomegalovirus DNAemia in hematological patients undergoing CD19-directed CAR-T cell therapy: should it be systematically monitored?

Solano de la Asuncion, Carlos; (...); Navarro, David

Letter. 10.1016/j.cmi.2023.05.010. 2023


Data-Driven Multiparameter Flow Cytometry (MFC) Classification of Blast Differentiation in Elderly Patients with Acute Myeloid Leukemia (AML)

Gonzalez, Carmen; (...); Paiva, Bruno

Meeting Abstract. 10.1182/blood-2023-180646. 2023

  • Open Access.

Disseminated toxoplasma infection after hematopoietic stem cell transplantation with myositis and encephalitis.

Asensi Cantó P; (...); Guerreiro M

Article. 10.1111/tid.14067. 2023

  • Open Access.

Early-Onset Myelodysplastic Syndromes (MDS) with Ring Sideroblasts (RS) without SF3B1 Mutations in Adults: Enrichment with Germline Variants in Genes Responsible for Congenital Sideroblastic Anemias

Jauregui, Sandra Novoa; (...); Jerez, Andres

Meeting Abstract. 10.1182/blood-2023-185836. 2023

  • Open Access.

Epidemiology and clinical description of Chagas disease in Valencia, Spain, from 2010 to 2020

Lozano, Noelia; (...); Calabuig, Eva

Article. 10.1016/j.actatropica.2024.107458. 2024

  • Open Access.

Evolution of the Genetic and Biological Studies Performed at Diagnosis in Patients with Acute Myeloid Leukemia Included in the Pethema Epidemiological Registry (REALMOL Study)

Labrador, Jorge; (...); Manuel Alonso-Dominguez, Juan

Meeting Abstract. 10.1182/blood-2022-163016. 2022

  • Open Access.

Evolving Indications for Heart-Lung Transplant in Spain.

Lopez-Vilella, Raquel; (...); Almenar Bonet, Luis

Article. 10.1016/j.transproceed.2022.10.003. 2022


Evolving patterns and clinical outcome of genetic studies performed at diagnosis in acute myeloid leukemia patients: Real life data from the PETHEMA Registry.

Labrador, Jorge; (...); Montesinos, Pau

Article. 10.1002/cncr.35431. 2024

  • Open Access.

Executive summary: Guidelines for the diagnosis and treatment of septic arthritis in adults and children, developed by the GEIO (SEIMC), SEIP and SECOT

Benito, Natividad; (...); Saavedra-Lozano, Jesus

Article. 10.1016/j.eimc.2023.07.003. 2024

  • Open Access.

Executive summary: Guidelines for the diagnosis and treatment of septic arthritis in adults and children, developed by the GEIO (SEIMC), SEIP and SECOT.

Benito, Natividad; (...); Saavedra-Lozano, Jesus

Practice Guideline. 10.1016/j.eimce.2023.07.007. 2023


Experience With Elexacaftor/Tezacaftor/Ivacaftor in Patients With Cystic Fibrosis and Advanced Disease.

Carrasco Hernandez, Laura; (...); Quintana Gallego, Esther

Article. 10.1016/j.arbres.2023.05.017. 2023

  • Open Access.

Exploring Potential Molecular Mechanisms of Drug Response in FLT3-ITD Negative AML Patients Treated with Quizartinib Vs Placebo Plus Standard Chemotherapy in the Quiwi Trial

Mosquera Orgueira, Adrian; (...); Montesinos, Pau

Meeting Abstract. 10.1182/blood-2023-180710. 2023


Floating Knee Arthrodesis after Periprosthetic Knee Infection: A Multi-Center Study.

Ortega-Yago, Amparo; (...); Baeza-Oliete, Jose

Article. 10.1016/j.arth.2024.12.009. 2024


Floating Knee Arthrodesis After Prosthetic Knee Infection: A Report of 48 Cases.

Ortega-Yago A; (...); Baeza-Oliete J

Article. 10.1016/j.arth.2023.08.011. 2023


Fluconazole-resistant Candida parapsilosis: fast detection of the Y132F ERG11p substitution, and a proposed microsatellite genotyping scheme.

Guinea, Jesus; (...); Escribano, Pilar

Article. 10.1016/j.cmi.2024.07.002. 2024


Fungal microbiota dynamics and its geographic, age and gender variability in patients with cystic fibrosis.

Martinez-Rodriguez, Sara; (...); Horra C

Article. 10.1016/j.cmi.2022.11.001. 2022


Genetic Characterization of Extensively Drug-Resistant Shigella sonnei Infections, Spain, 2021-2022

Jacqueline, Camille; (...); Herrera-Leon, Silvia

Article. 10.3201/eid2911.221746. 2023

  • Open Access.

Genomic characterization of MRSA recovered from people with cystic fibrosis during two Spanish multicentre studies (2013 and 2021).

Maruri-Aransolo A; (...); Caballero-Pérez JD

Article. 10.1093/jacamr/dlae160. 2024

  • Open Access.

Genomics improves risk stratification of adults with T-cell acute lymphoblastic leukemia patients enrolled in measurable residual disease-oriented trials.

Gonzalez-Gil, Celia; (...); Genesca, Eulalia

Article. 10.3324/haematol.2022.281196. 2023

  • Open Access.

Gradient diffusion strips for detecting azole resistance in Aspergillus fumigatus sensu lato.

Serrano-Lobo J; (...); ASPEIN Study Group

Article. 10.1111/myc.13541. 2022

  • Open Access.

Healthcare resource use and costs related to surgical infections of tibial fractures in a Spanish cohort.

Barres-Carsi, Mariano; (...); Balfagon, Antonio

Article. 10.1371/journal.pone.0277482. 2022

  • Open Access.

Host-pathogen interactions upon Candida auris infection: fungal behaviour and immune response in Galleria mellonella

Garcia-Bustos, Victor; (...); Ruiz-Sauri, Amparo

Article. 10.1080/22221751.2021.2017756. 2022

  • Open Access.

Human papilloma virus DNA detection in clinical samples using fluorogenic probes based on oligonucleotide gated nanoporous anodic alumina films.

Hernández-Montoto A; (...); Martínez-Máñez R

Article. 10.1002/adhm.202203326. 2023

  • Open Access.

Identification of the Most Immunoreactive Antigens of Candida auris to IgGs from Systemic Infections in Mice.

Areitio M; (...); Ramirez-Garcia A

Article. 10.1021/acs.jproteome.3c00752. 2024

  • Open Access.

IFISTRATEGY: Spanish National Survey of Invasive Fungal Infection in Hemato-Oncologic Patients.

Vallejo, Carlos; (...); Peman, Javier

Article. 10.3390/jof9060628. 2023

  • Open Access.

IgG antibody response to pneumococcal-conjugated vaccine (Prevenar®13) in children with immunodeficiency disorders.

Garrido-Jareño M; (...); Pemán-García J

Article. 10.1007/s00430-022-00759-0. 2023

  • Open Access.

Impact of Center-related Characteristics and Macroeconomic Factors on the Outcome of Adult Patients With Acute Lymphoblastic Leukemia Treated With Pediatric-inspired Protocols.

Barba P; (...); Ribera JM

Article. 10.1097/HS9.0000000000000810. 2023

  • Open Access.

IMPACT OF CYTOGENETIC ABNORMALITIES DEFINING AML MYELODYSPLASIA-RELATED (WHO AND ICC 2022) IN FIRST LINE DECITABINE IN UNFIT AML PATIENTS

de la Fuente, Adolfo; (...); Tormo, Mar

Meeting Abstract. 2023


Impact of FLT3-ITD Mutation Status and Its Ratio in a Cohort of 2901 Patients Undergoing Upfront Intensive Chemotherapy: A PETHEMA Registry Study.

Ayala, Rosa; (...); Montesinos, Pau

Article. 10.3390/cancers14235799. 2022

  • Open Access.

Impact of trisomy 19 on outcome according to genetic makeup in patients with acute myeloid leukemia.

Kayser, Sabine; (...); Schlenk, Richard F.

Article. 10.3324/haematol.2022.282127. 2023

  • Open Access.

Incidence, risk factors, and outcomes of BK hemorrhagic cystitis in hematopoietic stem cell transplantation from HLA-matched and haploidentical donors with post-transplant cyclophosphamide.

Chorao, Pedro; (...); Sanz, Jaime

Article. 10.1016/j.jtct.2024.12.006. 2024

  • Open Access.

Indolent Acute Myeloid Leukemia with Long Survival in Patients Treated with Best Supportive Care Only: A Pethema Registry Study

Labrador, Jorge; (...); Montesinos, Pau

Meeting Abstract. 10.1182/blood-2022-162591. 2022


Long-term antibacterial Ag plus -release biomaterials based on anodized Ti6Al4V and silver nanoparticles

Molina, J.; (...); Tormo-Mas, M. A.

Article. 10.1016/j.colsurfa.2023.132243. 2023


Machine Learning Improves Risk Stratification in Myelodysplastic Neoplasms: An Analysis of the Spanish Group of Myelodysplastic Syndromes.

Mosquera Orgueira, Adrian; (...); Valcarcel, David

Article. 10.1097/HS9.0000000000000961. 2023

  • Open Access.

Mechanical resistance of polylactic acid bone matrices developed by 3D printing for the reconstruction of bone defects.

Ortega-Yago A; (...); Medina-Bessó P

Article. 10.1016/j.recot.2023.02.001. 2023


Molecular Landscape and Validation of New Genomic Classification in 2668 Adult AML Patients: Real Life Data from the PETHEMA Registry.

Sargas, Claudia; (...); On Behalf Of Pethema Group

Article. 10.3390/cancers15020438. 2023

  • Open Access.

Nanoemulsion Increases the Antifungal Activity of Amphotericin B against Four Candida auris Clades: In Vitro and In Vivo Assays.

Marena, Gabriel Davi; (...); Peman, Javier

Article. 10.3390/microorganisms11071626. 2023

  • Open Access.

Neutralizing antibodies after nebulized phage therapy in cystic fibrosis patients.

Bernabeu-Gimeno, Mireia; (...); Domingo-Calap, Pilar

Article. 10.1016/j.medj.2024.05.017. 2024

  • Open Access.

OPTIMIZING MANAGEMENT AND OUTCOMES OF ACTIVATED PHOSPHOINOSITIDE 3-KINASE DELTA SYNDROME (APDS) IN SPAIN: BEWAYAPDS PROJECT

Flores-Moreno, S.; (...); Gil, A.

Meeting Abstract. 2024


Outcomes after intensive chemotherapy for secondary and myeloid-related changes acute myeloid leukemia patients aged 60 to 75 years old: a retrospective analysis from the PETHEMA registry

Martinez-Cuadron, David; (...); Montesinos, Pau

Article. 10.3324/haematol.2022.282506. 2024

  • Open Access.

Pethema NGS-AML Project. Final Analysis and Clinical Validation of New Genomic Classifications

Sargas, Claudia; (...); Montesinos, Pau

Meeting Abstract. 10.1182/blood-2022-166639. 2022

  • Open Access.

Position paper: Models of post-transplant care for individuals with cystic fibrosis.

McKone, Edward; (...); Pilewski, Joseph M.

Article. 10.1016/j.jcf.2023.02.011. 2023

  • Open Access.

Potential Fungal Zoonotic Pathogens in Cetaceans: An Emerging Concern

Garcia-Bustos, Victor; (...); Rosario Medina, Inmaculada

Review. 10.3390/microorganisms12030554. 2024

  • Open Access.

Pregnancy and fertility in people with cystic fibrosis following lung transplantation.

Taylor-Cousar JL, Sole A, Jain R

Article. 10.1097/MCP.0000000000001117. 2024

  • Open Access.

Prognostic Impact of NPM1 and FLT3-ITD Mutations in Patients Treated with Non-Intensive Regimens: A Pethema Registry Study

Uriel Suarez, Edwin; (...); Montesinos, Pau

Meeting Abstract. 10.1182/blood-2022-167365. 2022

  • Open Access.

Question 54: What are the indications for using sleeves and/or cones during revision total knee arthroplasty?

Fraval A; (...); Rajgopal A

Article. 10.1016/j.arth.2024.10.077. 2024


Real-World Outcomes Using Front-Line Midostaurine in Combination with Intensive Chemotherapy for Patients Aged = 60 Years Old with FLT3 Mutated Acute Myeloid Leukemia

Requena, Gaspar Aspas; (...); Matinez-Cuadron, David

Meeting Abstract. 10.1182/blood-2023-190128. 2023

  • Open Access.

Rickettsioses imported by travellers and migrants to Spain attended in the+Redivi network, 2009-2020.

Llenas-Garcia, Jara; (...); Perez-Molina, Jose A.

Article. 10.1093/jtm/taad050. 2023

  • Open Access.

Role of the first WHO mutation catalogue in the diagnosis of antibiotic resistance in Mycobacterium tuberculosis in the Valencia Region, Spain: a retrospective genomic analysis.

Garcia-Marin, Ana Maria; (...); Comas, Inaki

Article. 10.1016/S2666-5247(23)00252-5. 2024

  • Open Access.

Safety and effectiveness of isavuconazole in real-life non-neutropenic patients.

Monzo-Gallo, Patricia; (...); Garcia-Vidal, Carolina

Article. 10.1016/j.ijid.2024.107070. 2024

  • Open Access.

Salvage Therapy with Second-Generation Inhibitors for FLT3 Mutated Acute Myeloid Leukemia: A Real-World Study by the CETLAM and PETHEMA Groups

Vives, Susana; (...); PETHEMA Grp

Article. 10.3390/cancers16234028. 2024

  • Open Access.

SARS-CoV-2 N protein IgG antibody detection employing nanoporous anodized alumina: A rapid and selective alternative for identifying naturally infected individuals in populations vaccinated with spike protein (S)-based vaccines

Esteve-Sanchez, Yoel; (...); Climent, Estela

Article. 10.1016/j.snb.2024.136378. 2024

  • Open Access.

SARS-CoV-2-reactive antibody waning, booster effect and breakthrough SARS-CoV-2 infection in hematopoietic stem cell transplant and cell therapy recipients at one year after vaccination.

Pinana, Jose Luis; (...); Solano, Carlos

Article. 10.1038/s41409-023-01946-0. 2023

  • Open Access.

Study of pediatric invasive pneumococcal disease in the 13-pneumococcal conjugated vaccine era.

Garrido-Jareno, Marta; (...); Peman, Javier

Article. 10.1016/j.diagmicrobio.2024.116532. 2024


Supervised Machine Learning Improves Risk Stratification in Newly Diagnosed Myelodysplastic Syndromes: An Analysis of the Spanish Group of Myelodysplastic Syndromes

Mosquera Orgueira, Adrian; (...); Valcarcel, David

Meeting Abstract. 10.1182/blood-2022-159429. 2022

  • Open Access.

Switching from immediate- to extended-release cysteamine in patients with nephropathic cystinosis: from clinical trials to clinical practice.

Ariceta G; (...); Vara J

Article. 10.1093/ckj/sfae049. 2024

  • Open Access.

The Ecology of Non-Candida Yeasts and Dimorphic Fungi in Cetaceans: From Pathogenicity to Environmental and Global Health Implications.

Garcia-Bustos, Victor; (...); Rosario Medina, Inmaculada

Article. 10.3390/jof10020111. 2024

  • Open Access.

The FLT3-like Gene Expression Signature Predicts Response to Quizartinib in Wild-Type FLT3 Acute Myeloid Leukemia: An Analysis of the Pethema Quiwi Trial

Mosquera Orgueira, Adrian; (...); Montesinos, Pau

Meeting Abstract. 10.1182/blood-2023-180482. 2023

  • Open Access.

The Optimization of the Synthesis of Antibacterial Coatings on Ti6Al4V Coupons Obtained by Electron Beam Melting

Molina, Javier; (...); Bosch, Francisco

Article. 10.3390/met14080855. 2024

  • Open Access.

The transcriptomic landscape of elderly acute myeloid leukemia identifies B7H3 and BANP as a favorable signature in high-risk patients.

Villar, Sara; (...); Montesinos, Pau

Article. 10.3389/fonc.2022.1054458. 2022

  • Open Access.

Torque Teno Virus plasma DNA load: a novel prognostic biomarker in CAR-T therapy

Benzaquen, Ana; (...); Solano, Carlos

Article. 10.1038/s41409-023-02114-0. 2024

  • Open Access.

Transcriptional and Genomic Characterization of Measurable Residual Disease (MRD) Cells in Acute Myeloid Leukemia (AML)

Patricia Simoes, Catia; (...); Paiva, Bruno

Meeting Abstract. 10.1182/blood-2022-163159. 2022

  • Open Access.

Transcriptional and genomic characterization of measurable residual disease in acute myeloid leukaemia.

Simoes, Catia; (...); Montesinos, Pau

Letter. 10.1111/bjh.18815. 2023

  • Open Access.

Treatment Outcomes in Unfit Patients with Newly Acute Myeloid Leukemia According to IDH1 Mutational Status: Real World Evidence from the Pethema Epidemiologic Registry

Martinez-Cuadron, David; (...); Montesinos, Pau

Meeting Abstract. 10.1182/blood-2023-189800. 2023

  • Open Access.

Trends in imported infections among migrants and travellers to Spain: a decade of analysis through the +Redivi network (2012-2022).

Alkaissy Y; (...); Perez-Molina JA

Article. 10.1093/jtm/taae067. 2024

  • Open Access.

Use of sera cell free DNA (cfDNA) and exovesicle-DNA for the molecular diagnosis of chronic Chagas disease.

Lozano N; (...); Osuna A

Article. 10.1371/journal.pone.0282814. 2023

  • Open Access.

Usefulness of Chromogenic Media with Fluconazole Supplementation for Presumptive Identification of Candida auris.

Ruiz-Gaitan, Alba; (...); Peman, Javier

Article. 10.3390/diagnostics13020231. 2023

  • Open Access.

Validation of the Artificial Intelligence Prognostic Scoring System for Myelodysplastic Syndromes in chronic myelomonocytic leukaemia: A novel approach for improved risk stratification.

Mosquera Orgueira, Adrian; (...); Valcarcel, David

Article. 10.1111/bjh.19341. 2024

  • Open Access.

What is the optimal interval between bilateral total knee or total hip arthroplasty when performed under separate anesthesia?

Poultsides L; (...); Memtsoudis S

Article. 10.1016/j.arth.2024.10.091. 2024


WHO and ICC 2022 Cytogenetic Abnormalities Defining Acute Myelogenous Leukemia (AML) Myelodysplasia-Related in First-Line Decitabine in Unfit AML Patients

Ortiz Lopez, Alicia; (...); de la Fuente Burguera, Adolfo

Meeting Abstract. 2023


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