Portal de investigación
ESTUDIO DE CONTINUACIÓN ABIERTO Y MULTICÉNTRICO PARA EVALUAR LA SEGURIDAD, LA TOLERABILIDAD Y LA EFICACIA DE LA ADMINISTRACIÓN A LARGO PLAZO DE GANTENERUMAB EN PARTICIPANTES CON ENFERMEDAD DE ALZHEIMER.
Datos básicos
- Protocolo:
- WN42171
- EUDRACT:
- 2020-000766-42
- NCT:
- Centro:
- HOSPITAL UNIVERSITARI I POLITÈCNIC LA FE
- Año de incio:
- 2021
- Año de finalización:
- 2025
Documentos
- No hay documentos
Participantes
Grupos
Financiadores - Promotores
Resultados del Ensayo Clínico
[[Tranaslated article]]Primary Cutaneous Lymphoma Registry of the Spanish Academy of Dermatology and Venereology (AEDV): Data for the First 5 Years.
López DF; (...); Ortiz-Romero, P. L.
Article. 10.1016/j.ad.2022.11.013. 2023
A multicriteria decision analysis (MCDA) applied to three long-term prophylactic treatments for hereditary angioedema in Spain
Zozaya, Neboa; (...); Hidalgo-Vega, Alvaro
Article. 10.33393/grhta.2022.2333. 2022
A multi-criteria decision analysis on the value of nintedanib for interstitial lung diseases.
Zozaya, Neboa; (...); Verde, Luis
Article. 10.1017/S0266462322000459. 2022
Accuracy and prognostic impact of FDG PET/CT and biopsyin bone marrow assessment of follicular lymphomaat diagnosis: A Nation-Wide cohort study.
Rodenas-Quinonero, Isabel; (...); Ortuno, Francisco Jose
Article. 10.1002/cam4.5424. 2022
Analysis of chemical contamination by hazardous drugs with BD HD Check(R) system in a tertiary hospital
Valero García S; (...); Poveda Andrés JL
Article. 10.1177/10781552211038518. 2021
Angiotensin II Receptor Blockers Reduce Tau/ASS42 Ratio: A Cerebrospinal Fluid Biomarkers' Case-Control Study.
Garcia-Lluch, Gemma; (...); Chafer-Pericas, Consuelo
Article. 10.3390/pharmaceutics15030924. 2023
Artificial Intelligence on FDG PET Images Identifies Mild Cognitive Impairment Patients with Neurodegenerative Disease.
Prats-Climent, Joan; (...); Marti-Bonmati, Luis
Article. 10.1007/s10916-022-01836-w. 2022
Assessment of apolipoprotein E genotype for ß-amyloid status prediction.
Peña-Bautista C; (...); Chafer-Pericas, Consuelo
Article. 10.2174/1567205019666211223141524. 2021
Assessment of COVID-19 lockdown effect on early Alzheimer Disease progression.
Pena-Bautista, Carmen; (...); Chafer-Pericas, Consuelo
Article. 10.1007/s00415-023-11899-5. 2023
Assessment of Lipid Peroxidation in Alzheimer's Disease Differential Diagnosis and Prognosis.
Ferre-Gonzalez, Laura; (...); Chafer-Pericas, Consuelo
Article. 10.3390/antiox11030551. 2022
Assessment of Plasma and Cerebrospinal Fluid Biomarkers in Different Stages of Alzheimer's Disease and Frontotemporal Dementia.
Álvarez-Sánchez L; (...); Cháfer-Pericás C
Article. 10.3390/ijms24021226. 2023
Assessment of Screening Approach in Early and Differential Alzheimer's Disease Diagnosis.
Ferré-González L; (...); Cháfer-Pericás C
Article. 10.3390/antiox10111662. 2021
Attitudes toward seeking professional help among patients with early Alzheimer's disease
Villarejo-Galende, A.; (...); Maurino, J.
Meeting Abstract. 2023
Author Correction: Brain areas lipidomics in female transgenic mouse model of Alzheimer's disease.
Ferré-González L; (...); Cháfer-Pericás C
Correction. 10.1038/s41598-024-52528-z. 2024
Awareness of Diagnosis in Persons with Early-Stage Alzheimer's Disease: An Observational Study in Spain.
Villarejo-Galende, Alberto; (...); Maurino, Jorge
Article. 10.1007/s40120-022-00367-3. 2022
Baricitinib against severe COVID-19: effectiveness and safety in hospitalised pretreated patients.
Iglesias Gómez R; (...); Poveda Andrés JL
Article. 10.1136/ejhpharm-2021-002741. 2021
Bioavailability of once-daily tacrolimus formulations used in clinical practice in the management of De Novo kidney transplant recipients: the better study.
Fernandez Rivera C; (...); Hernandez D
Article. 10.1111/ctr.14550. 2022
Brain areas lipidomics in female transgenic mouse model of Alzheimer's disease
Ferre-Gonzalez, Laura; (...); Chafer-Pericas, Consuelo
Article. 10.1038/s41598-024-51463-3. 2024
Clinical benefits of a Bayesian model for plasma-derived factor VIII/VWF after one year of pharmacokinetic-guided prophylaxis in severe/moderate hemophilia A patients
Megias-Vericat, JE; (...); Poveda, JL
Article. 10.1016/j.thromres.2021.07.009. 2021
Clinical usefulness of cerebrospinal fluid biomarkers in Alzheimer Disease.
Pena-Bautista, Carmen; (...); Chafer-Pericas, Consuelo
Article. 10.1111/eci.13910. 2022
Cluster headache. Are there differences by gender?
Olivier, M. A.; (...); Diaz Insa, S.
Meeting Abstract. 2024
COGNITIVE FUNCTION FOLLOWING AN INTRACEREBRAL HEMORRHAGE ASSOCIATED WITH CEREBRAL AMYLOID ANGIOPATHY.
Gimenez, C; (...); Lago, A
Meeting Abstract. 2020
Comparison of 3D dosimetry methods in hepatic radioembolisation with Y-90 microspheres
Carrasco Vela, N.; (...); Torres-Espallardo, I.
Meeting Abstract. 2021
Comparison of protocols with respiratory-gated (4D) motion compensation in PET/CT: open-source package for quantification of phantom image quality.
Martinez-Movilla, Andrea; (...); Carles, Montserrat
Article. 10.1186/s40658-022-00509-4. 2022
Consensus recommendations for the improvement of inter- and intra-centre care coordination in the management of hemophilia.
Montoro-Ronsano JB; (...); Soto-Ortega I
Article. 10.1016/j.farma.2023.01.003. 2023
Consensus recommendations for the improvement of inter- and intra-centre care coordination in the management of hemophilia.
Montoro-Ronsano, Jose Bruno; (...); Soto-Ortega, Inmaculada
Article. 10.1016/j.farma.2023.04.002. 2023
Costs of the management of hemophilia A with inhibitors in Spain
Bonanad, S; (...); Gonzalez-Dominguez, A
Article. 10.33393/grhta.2021.2234. 2021
Defining Alzheimer's Disease through Proteomic CSF Profiling.
Pena-Bautista, Carmen; (...); Chafer-Pericas, Consuelo
Article. 10.1021/acs.jproteome.4c00590. 2024
Depression and Suicide Risk in Mild Cognitive Impairment: The Role of Alzheimer's Disease Biomarkers
Ferrer-Cairols, Ines; (...); Salvador, Alicia
Article. 10.7334/psicothema2022.103. 2022
Design and rationale for a real-world prospective, multicenter registry of myocardial revascularization failure and secondary revascularization: The REVASEC study.
Salinas P; (...); Escaned J
Article. 10.1016/j.carrev.2021.11.015. 2021
Discordant Amyloid Status Diagnosis in Alzheimer's Disease.
García-Vallés L; (...); Cháfer-Pericás C
Article. 10.3390/biomedicines10112880. 2022
Early Alzheimer's Disease Screening Approach Using Plasma Biomarkers
Alvarez-Sanchez, Lourdes; (...); Chafer-Pericas, Consuelo
Article. 10.3390/ijms241814151. 2023
Effectiveness of Caplacizumab Nanobody in Acquired Thrombotic Thrombocytopenic Purpura Refractory to Conventional Treatment
Palanques-Pastor T; (...); Poveda Andrés JL
Article. 10.1159/000517813. 2021
Emotion recognition and baseline cortisol levels relationship in early Alzheimer Disease.
Ferrer-Cairols, I.; (...); Chafer-Pericas, C.
Article. 10.1016/j.biopsycho.2023.108511. 2023
Epigenomics and Lipidomics Integration in Alzheimer Disease: Pathways Involved in Early Stages.
Peña-Bautista C; (...); Chafer-Pericas, Consuelo
Article. 10.3390/biomedicines9121812. 2021
Fast Declining Prediction in Alzheimer's Disease from Early Clinical Assessment.
Álvarez-Sánchez L; (...); Pericás CC
Article. 10.2174/011570159X332930240925095423. 2024
Fetal exposure to tofacitinib during the first trimester: A healthy newborn case report
Fernandez-Sanchez, M; (...); Poveda-Andres, JL
Article. 10.1002/bdr2.1942. 2021
Guide to Good Humanization Practices in Patients with Rare Diseases. who vadis
Editorial Material. 2022
Healthcare Resource Utilization among Patients between 60-75 Years with Secondary Acute Myeloid Leukemia Receiving Intensive Chemotherapy Induction: A Spanish Retrospective Observational Study
Solana-Altabella, Antonio; (...); Martinez-Cuadron, David
Article. 10.3390/cancers14081921. 2022
High incidence of pulmonary thromboembolism in hospitalized SARS-CoV-2 infected patients despite thrombo-prophylaxis.
El-Qutob D; (...); Carrera-Hueso FJ
Article. 10.1016/j.hrtlng.2022.02.003. 2022
Hospital pharmacy initiatives for improving the management of patients with congenital coagulopathies
Bruno Montoro-Ronsano, Jose; (...); Alberto Vella, Vincenzo
Article. 10.7399/fh.11729. 2022
Hospitalization budget impact during the COVID-19 pandemic in Spain.
Carrera-Hueso, F. J.; (...); Crespo-Palomo, C.
Article. 10.1186/s13561-021-00340-0. 2021
How can artificial intelligence optimize value-based contracting?
Poveda, Jose Luis; (...); Medrano, Ignacio H.
Letter. 10.1186/s40545-022-00475-3. 2022
Imaging Biomarkers in Amyotrophic Lateral Sclerosis
Cerda Alberich, Leonor; (...); Marti-Bonmati, Luis
Editorial Material. 10.1007/978-1-0716-1712-0_20. 2022
Influence of polymorphisms in anthracyclines metabolism genes in the standard induction chemotherapy of acute myeloid leukemia.
Megías-Vericat JE; (...); Montesinos P
Article. 10.1097/FPC.0000000000000431. 2021
Insights from a 7-Year Dementia Cohort (VALCODIS): ApoE Genotype Evaluation.
Baquero, Miguel; (...); Chafer-Pericas, Consuelo
Article. 10.3390/jcm13164735. 2024
Labyrinthine Bifurcation of the Facial Nerve
Saro-Buendia, Miguel; (...); Carceller, Miguel Armengot
Article. 10.1007/s12070-023-03977-x. 2023
Lipid Peroxidation Assessment in Preclinical Alzheimer Disease Diagnosis
Pena-Bautista, Carmen; (...); Cháfer-Pericás C
Article. 10.3390/antiox10071043. 2021
Lipids as early and minimally invasive biomarkers for Alzheimer disease.
Casas-Fernandez, Esther; (...); Chafer-Pericas, Consuelo
Article. 10.2174/1570159X19666211102150955. 2021
Management of flexible cavovarus foot in patients with Charcot-Marie-Tooth disease: midterm results.
Megías-Vericat JE; (...); Poveda-Andrés JL
Article. 2021
Manipulación de fármacos para su administración por gastrostomía endoscópica percutánea en pacientes con esclerosis lateral amiotrófica y nutrición enteral.
Vázquez Polo A; (...); Vázquez Costa JF
Article. 10.20960/nh.03946. 2022
Matching-Adjusted Indirect Comparison of Efficacy and Consumption of rVIII-SingleChain Versus Two Recombinant FVIII Products Used for Prophylactic Treatment of Adults/Adolescents with Severe Haemophilia A
Bonanad, S; (...); Santos, S
Article. 10.1007/s12325-021-01853-0. 2021
Metabolic Phenotyping in Prostate Cancer Using Multi-Omics Approaches.
Gomez-Cebrian, Nuria; (...); Puchades-Carrasco, Leonor
Article. 10.3390/cancers14030596. 2022
Misfolded alpha-synuclein detection by RT-QuIC in dementia with lewy bodies: a systematic review and meta-analysis.
Peña-Bautista C; (...); Ferreira D
Article. 10.3389/fmolb.2023.1193458. 2023
Monitoring contamination of hazardous drug compounding surfaces at hospital pharmacy departments. A consensus Statement. Practice guidelines of the Spanish Society of Hospital Pharmacists (SEFH).
Valero-García S; (...); Delgado-Sánchez O
Article. 10.7399/fh.11655. 2021
Multi-Omic Approaches to Breast Cancer Metabolic Phenotyping: Applications in Diagnosis, Prognosis, and the Development of Novel Treatments
Gomez-Cebrian, N; (...); Pineda-Lucena, A
Review. 10.3390/cancers13184544. 2021
National Survey of the SEFH-2019: portfolio of services, healthcare activity, teaching and research in Hospital Pharmacy Services in Spain (vol 45, pg 32, 2021)
Perez-Encinas, Montserrat; (...); Angel Calleja-Hernandez, Miguel
Correction. 10.7399/fh.11740. 2021
National Survey on the Use of Mobile Applications in Patients with Hemophilia and Other Coagulopathies
Eduardo Megias, Juan; (...); Poveda Andres, Jose Luis
Meeting Abstract. 10.1182/blood-2022-169938. 2022
New insights into the genetic etiology of Alzheimer's disease and related dementias
Bellenguez, Celine; (...); CHARGE
Article. 10.1038/s41588-022-01024-z. 2022
Novel Ultrasensitive Detection Technologies for the Identification of Early and Minimally Invasive Alzheimer's Disease Blood Biomarkers.
Alvarez-Sanchez, Lourdes; (...); Chafer-Pericas, Consuelo
Article. 10.3233/JAD-215093. 2022
Nuclear-medicine probes: Where we are and where we are going
Gonzalez-Montoro A; (...); Javier Gonzalez, Antonio
Article. 10.1002/mp.15690. 2022
Observational study to evaluate discontinuation of monotherapy with cobicistat-boosted darunavir in patients with human immunodeficiency virus
Solana-Altabella, Antonio; (...); Poveda-Andres, Jose Luis
Article. 10.1097/MD.0000000000032208. 2022
ODs with a positive TPR conclusion, not subject to a conditional approval, and approved without requering a pass would be more likely to be reimbursed in Spain.
Poveda JL; (...); Badia X
Article. 10.1186/s13023-022-02610-4. 2023
Onabotulinum Toxin A (OnA) as a preventive treatment for non-migraine headaches: a retrospective analysis
Nieves Castellanos, C.; (...); Diaz Insa, S.
Meeting Abstract. 2024
Paracetamol vs. Ibuprofen in Preterm Infants With Hemodynamically Significant Patent Ductus Arteriosus: A Non-inferiority Randomized Clinical Trial Protocol (vol 8, 372, 2020)
Garcia-Robles, Ana; (...); Aguar Carrascosa, Marta
Correction. 10.3389/fped.2021.834454. 2022
Patient and health practitioner perceptions about the role of hospital pharmacists along the care continuum: the Fharmaconectados Project
Morillo-Verdugo, R; (...); Diaz-Olmo, J
Article. 10.7399/fh.11719. 2021
Patient and health practitioner perceptions about the role of hospital pharmacists along the care continuum: the Fharmaconectados Project.
Morillo-Verdugo R; (...); Díaz-Olmo J
Article. 2021
Person-centered Assessment in Early Alzheimers Disease (P1-1.Virtual)
Villarejo Galende, Alberto; (...); Maurino, Jorge
Meeting Abstract. 2022
Pharmacometabolomics by NMR in Oncology: A Systematic Review.
Gómez-Cebrián N; (...); Pineda-Lucena A
Article. 10.3390/ph14101015. 2021
Pharmacotherapeutic management of advanced therapy medicinal products
Luis Poveda-Andres, Jose; (...); Valero-Garcia, Silvia
Article. 10.7399/fh.13036. 2022
Plasma Lipidomics Approach in Early and Specific Alzheimer's Disease Diagnosis.
Pena-Bautista, Carmen; (...); Chafer-Pericas, Consuelo
Article. 10.3390/jcm11175030. 2022
Plasma lipidomics in early APP/PS1 female mouse model and its relationship with brain: Is it affected by the estrous cycle?
Ferre-Gonzalez, Laura; (...); Chafer-Pericas, Consuelo
Article. 10.1186/s13195-024-01549-x. 2024
Posterior Lingual Abscess; Report of Two Cases.
Saro-Buendia, Miguel; (...); Armengot Carceller, Miguel
Case Reports. 10.22037/aaem.v11i1.1860. 2023
Preparation and administration of insulin infusions in neonatology: A national survey.
Garcia-Robles, Ana; (...); Aguar Carrascosa, Marta
Article. 10.1016/j.anpede.2020.06.015. 2021
Presenilin-1 Mutations Are a Cause of Primary Lateral Sclerosis-Like Syndrome
Vazquez-Costa, JF; (...); SEVILLA, T
Article. 10.3389/fnmol.2021.721047. 2021
Primary Cutaneous Lymphoma Registry of the Spanish Academy of Dermatology and Venereology (AEDV): Data for the First 5 Years.
Falkenhain-Lopez, D; (...); Ortiz-Romero, P L
Article. 10.1016/j.ad.2022.11.010. 2023
Prognostic value of cerebrospinal fluid biomarkers in mild cognitive impairment due to Alzheimer disease.
López-Cuevas R; (...); Cháfer-Pericás C
Article. 10.1016/j.nrl.2020.07.026. 2020
Prognostic value of cerebrospinal fluid biomarkers in mild cognitive impairment due to Alzheimer disease.
Lopez-Cuevas, R; (...); Chafer-Pericas, C
Article. 10.1016/j.nrleng.2020.07.024. 2023
Prognostic value of genetic alterations and (18)F-FDG PET/CT imaging features in diffuse large B cell lymphoma.
Ferrer-Lores B; (...); Terol MJ
Article. 10.2156/6976/ajcr0146852. 2023
Prognostic value of genetic alterations and 18F-FDG PET/CT imaging features in diffuse large B cell lymphoma
Ferrer-Lores, Blanca; (...); Terol, Maria Jose
Article. 10.2156/6976/ajcr0146852. 2023
Psychological intervention in refractory chronic migraine patients
Zambrano Camina, M.; (...); Diaz Insa, S.
Meeting Abstract. 2024
Quantitative evaluation of a non-CT based attenuation correction method for a new dedicated brain PET
Gandia-Ferrero, M.; (...); Marti-Bonmati, L.
Meeting Abstract. 2022
Radioembolization in patients with hepatocellular carcinoma: a series of 53 cases.
Olivan-Sasot, P; (...); Olivas-Arroyo, C
Article. 10.1016/j.rxeng.2021.03.001. 2023
Radiological evaluation of the postsurgical middle ear.
Mazon, M.; (...); Carreres-Polo, J.
Article. 10.1016/j.rx.2021.04.005. 2021
Radiological evaluation of the postsurgical middle ear.
Mazón M; (...); Carreres-Polo J
Article. 10.1016/j.rxeng.2021.04.006. 2021
Recent evidence in epigenomics and proteomics biomarkers for early and minimally invasive diagnosis of Alzheimer's and Parkinson's diseases.
Mayo, Sonia; (...); Chafer-Pericas, Consuelo
Review. 10.2174/1570159X19666201223154009. 2020
Role of the nigrosome 1 absence as a biomarker in amyotrophic lateral sclerosis
Isabel Moreno-Gambin, Maria; (...); Vázquez-Costa JF
Article. 10.1007/s00415-021-10729-w. 2021
SMPTall man lettering application in medication information systems as a quality and safety strategy in hospital organization
Iglesias Gomez, Ruben; (...); Poveda Andres, Jose Luis
Article. 10.1111/jcpt.13703. 2022
Spinocerebellar Ataxia 36 is a Frequent Cause of Hereditary Ataxia in Eastern Spain
Baviera-Munoz, Raquel; (...); Bataller, Luis
Article. 10.1002/mdc3.13740. 2023
Systematic review of brain and blood lipidomics in Alzheimer's disease mouse models.
Ferre-Gonzalez, Laura, Lloret, Ana, Chafer-Pericas, Consuelo
Article. 10.1016/j.plipres.2023.101223. 2023
Systematic Review of Pharmacogenetics of ABC and SLC Transporter Genes in Acute Myeloid Leukemia
Megías-Vericat JE; (...); Montesinos P
Review. 10.3390/pharmaceutics14040878. 2022
The association of salivary caffeine levels with serum concentrations in premature infants with apnea of prematurity
Garcia-Robles, Ana; (...); Saenz Gonzalez, Pilar
Article. 10.1007/s00431-022-04628-z. 2022
The contribution of fenfluramine to the treatment of Dravet syndrome in Spain through Multi-Criteria Decision Analysis.
Gil-Nagel A; (...); Gil A
Article. 10.1016/j.yebeh.2022.108711. 2022
The Role of Imaging Studies in Favor of Possible Cerebellar Multiple System Atrophy: A Case Study.
Utrera-Costero, Ana; (...); Bello-Arques, Pilar
Article. 10.1097/RLU.0000000000003767. 2021
The sentinel node with technetium-99m for prostate cancer. A safe and, mature new gold standard?
Perez-Ardavin J; (...); Vera-Donoso CD
Article. 10.23736/S1824-4785.22.03416-1. 2022