Portal de investigación
EVALUACIÓN DE LA SEGURIDAD DE LA ESTIMULACIÓN OVÁRICA CONTROLADA COMO TÉCNICA DE PRESERVACIÓN DE LA FERTILIDAD EN PAC IENTES CON CÁNCER DE MAMA.
Datos básicos
- Código:
- ISF-LET-2019-01
- Protocolo:
- ISF-LET-2019-01
- EUDRACT:
- NCT:
- Centro:
- HOSPITAL UNIVERSITARI I POLITÈCNIC LA FE
- Dotación:
- Año de incio:
- 2020
- Año de finalización:
- 2020
Documentos
- No hay documentos
Participantes
Grupos
Financiadores - Promotores
Resultados del Ensayo Clínico
15-year-experience in oncological fertility preservation: Impact on disease survival and reproductive outcomes
Subira, J.; (...); Diaz-Garcia, C.
Meeting Abstract. 2023
A new strategy to assess safety of controlled ovarian stimulation protocols for oocyte vitrification as a fertility preservation technique in breast cancer patients
Soriano, M. J.; (...); Diaz-Garcia, C.
Meeting Abstract. 2020
Adherence and adverse events of intraperitoneal chemotherapy in optimally debulked ovarian cancer patients: Real-life study.
Ballesta-López O; (...); Poveda-Andrés JL
Article. 10.1177/1078155220915953. 2020
Advances and controversies in management of breast ductal carcinoma in situ (DCIS).
Farante G; (...); Veronesi P
Article. 10.1016/j.ejso.2021.10.030. 2022
ANALYSIS OF THE CLINICAL EXPERIENCE WITHIN RUCAPARIB'S EARLY ACCESS PROGRAM IN SPAIN - A GEICO STUDY
Yubero-Esteban, A.; (...); Gonzalez-Martin, A.
Meeting Abstract. 10.1136/ijgc-2021-ESGO.398. 2021
AUTOLOGOUS PLATELET RICH PLASMA (PRP) INTRAOVARIAN INJECTION TO IMPROVE OVARIAN RESERVE PARAMETERS AND REPRODUCTIVE POTENTIAL IN POOR OVARIAN RESPONDER (POR) WOMEN UNDER 40 YEARS OLD
Molinaro, Pietro; (...); Munoz, Manuel
Meeting Abstract. 2023
Autologous stem cell ovarian transplant induced long-lasting effects on the plasma proteome of women with premature ovarian insufficiency
Buigues, A.; (...); Herraiz, S.
Meeting Abstract. 2023
AUTOLOGOUS STEM CELL OVARIAN TRANSPLANTATION (ASCOT) REVITALIZED THE AGED BLOOD-BORNE SECRETOME IN POOR RESPONDER (PR) WOMEN.
Pellicer, N; (...); Herraiz, S
Meeting Abstract. 10.1016/j.fertnstert.2019.07.1283. 2019
Bioengineering an Ovarian-Specific ECM Hydrogel to Treat Premature Ovarian Failure
Frances-Herrero, Emilio; (...); Cervello, Irene
Meeting Abstract. 2023
Bioengineering trends in female reproduction: a systematic review
Frances-Herrero, Emilio; (...); Cervello, Irene
Review. 10.1093/humupd/dmac025. 2022
Bone marrow derived stem cells restore ovarian function and fertility in premature ovarian insufficiency women. Interim report of a randomized trial: mobilization versus ovarian injection
De Castellvi, NP; (...); Pellicer, A.
Meeting Abstract. 2020
Circulating Follicular Fluid microRNAs as Potential Biomarkers for Endometriosis.
Jose Soriano, Maria; (...); Diaz-Garcia, Cesar
Meeting Abstract. 2023
Clinical and cost outcomes of a polyethylene glycol (PEG)-coated patch versus drainage after axillary lymph node dissection in breast cancer: results from a multicentre randomized clinical trial.
Buch-Villa E; (...); Ortega J
Article. 10.1093/bjs/znad150. 2023
Combination of Stem Cell Secreted and Platelet Enclosed Growth Factors Restores Ovarian Function in an Aging Mouse Model
Marchante, Maria; (...); Herraiz, Sonia
Meeting Abstract. 2022
Comparison of Outcomes of Covid-19 Between Fully Vaccinated and Unvaccinated Kidney Transplant Recipients and According to the Type of M-RNA Vaccine
Villanego, F.; (...); Mazuecos, A.
Meeting Abstract. 2022
Contribution of the D19S884 allele 8 of the FBN3 gene and the Hippo signaling to the reproductive and metabolic phenotype of PCOS patients
Ramirez Martin, N.; (...); Herraiz, S.
Meeting Abstract. 2022
Controlled ovarian stimulation protocols for oocyte vitrification induce differential gene expression profiles in primary tumours of breast cancer
Soriano, MJ; (...); Diaz-Garcia, C
Meeting Abstract. 2021
Correction to: Diminished Ovarian Reserve Chemotherapy-Induced Mouse Model: A Tool for the Preclinical Assessment of New Therapies for Ovarian Damage.
Buigues A; (...); Pellicer A
Correction. 10.1007/s43032-020-00379-0. 2021
Characterization of the gene expression profile of breast cancer tumours in patients undergoing ovarian stimulation for fertility preservation purposes
Soriano, M. J.; (...); Diaz-Garcia, C.
Meeting Abstract. 2022
Deciphering reproductive aging in women using a NOD/SCID mouse model for distinct physiological ovarian phenotypes.
Marchante, Maria; (...); Herraiz, Sonia
Article. 10.18632/aging.205086. 2023
Development, Implementation and Assessment of Molecular Diagnostics by Next Generation Sequencing in Personalized Treatment of Cancer: Experience of a Public Reference Healthcare Hospital.
Simarro J; (...); Palanca S
Article. 10.3390/cancers11081196. 2019
Dexamethasone does not prevent malignant cell reintroduction in leukemia patients undergoing ovarian transplant: risk assessment of leukemic cell transmission by a xenograft model
Diaz-Garcia, C; (...); Pellicer, A
Article. 10.1093/humrep/dez115. 2019
Differential effects of the immunosuppressive calcineurin inhibitors cyclosporine-A and tacrolimus on ovulation in a murine model.
Zakerkish F; (...); Díaz-García C
Article. 10.1093/hropen/hoab012. 2021
Diminished Ovarian Reserve Chemotherapy-Induced Mouse Model: A Tool for the Preclinical Assessment of New Therapies for Ovarian Damage
Buigues, A; (...); Pellicer, A
Article. 10.1007/s43032-020-00191-w. 2020
Disease-inducing potential of two leukemic cell lines in a xenografting model
Manavella DD; (...); Dolmans MM
Article. 10.1007/s10815-021-02169-2. 2021
Effect of aging on the human myometrium at single-cell resolution.
Punzon-Jimenez, Paula; (...); Mas, Aymara
Article. 10.1038/s41467-024-45143-z. 2024
EFFECT OF DISTAL CANCER ON THE TELOMERIC LENGTH OF OVARIAN CORTEX CELLS.
Chico-Sordo, L; (...); Varela, E
Meeting Abstract. 2020
Evaluation of salivary ELISA for Oestradiol and Progesterone monitoring in IVF patients
Bosch Aparicio, E.; (...); White, R.
Meeting Abstract. 2023
Evaluation of Time Interval Between Ovulation Trigger With Triptorelin Acetate and Oocyte Retrieval in IVF Cycles. A Randomized Controlled Trial
Diaz-Garcia, C.; (...); Pellicer, A.
Meeting Abstract. 2020
External validation of a prognostic model based on total tumor load of sentinel lymph node for early breast cancer patients
Pinero-Madrona, A; (...); Peg-Camara, V
Article. 10.1007/s10549-020-05623-4. 2020
Factors Associated With Increased Complications in Patients With BRCA Gene Mutations Undergoing Reconstructive Breast Surgery.
Vanaclocha N; (...); Sánchez García A
Article. 10.1097/PSN.0000000000000331. 2021
Fertility preservation for social or non medical reasons
Galian, M., Diaz, M., Diaz-Garcia, C.
Review. 10.1016/j.gine.2024.100970. 2024
First Spanish consensus on the use of intraoperative radiotherapy in breast cancer. Conclusions of the expert panel
Eraso, Arantxa; (...); Algara, Manuel
Review. 10.1016/j.senol.2023.100502. 2023
FOLLICULAR ACTIVATION IN POOR OVARIAN RESPONDERS (FAPPOR): A RANDOMIZED CONTROLLED TRIAL.
Diaz-Garcia, Cesar; (...); Pellicer, Antonio
Meeting Abstract. 2021
Follicular activation in women previously diagnosed with poor ovarian response: a randomized, controlled trial.
Díaz-García C; (...); Pellicer A
Article. 10.1016/j.fertnstert.2021.12.034. 2022
G-CSF Mobilized Plasma Regenerate Ovarian Stroma and Restore Ovarian Function.
Buigues, A; (...); Herraiz, S
Meeting Abstract. 2020
Growth factor-loaded ovarian extracellular matrix hydrogels promote in vivo ovarian niche regeneration and enhance fertility in premature ovarian insufficiency preclinical models.
Frances-Herrero, Emilio; (...); Cervello, Irene
Article. 10.1016/j.actbio.2024.07.056. 2024
High risk of thrombosis in patients with advanced lung cancer harboring rearrangements in ROS1.
Muñoz-Unceta N; (...); Grupo de trombosis y cáncer SEOM
Article. 10.1016/j.ejca.2020.10.002. 2020
Immunosuppressive profiles in liquid biopsy at diagnosis predict response to neoadjuvant chemotherapy in triple-negative breast cancer
Salvador-Coloma, C; (...); de Mora, JF
Article. 10.1016/j.ejca.2020.08.020. 2020
Impact of ABVD chemotherapy on ovarian reserve after fertility preservation in reproductive-aged women with Hodgkin lymphoma
Policiano C; (...); Rubio Rubio JM
Article. 10.1007/s10815-020-01844-0. 2020
Impaired telomere pathway and fertility in Senescence-Accelerated Mice Prone 8 females with reproductive senescence.
Polonio, Alba M.; (...); Varela, Elisa
Article. 10.18632/aging.204731. 2023
In vivo follicular activation (IVFA) through repeated ovarian punction: results of an experimental study in a premature ovarian insufficiency rodent model
Rico, R. Galan; (...); Diaz-Garcia, C.
Meeting Abstract. https://doi.org/10.1093/humrep/deae108.961. 2024
Integrative Molecular Profiling of Uterine Leiomyomas and Leiomyosarcomas Using DNA and RNA Sequencing: Preliminary Steps Toward Preoperative Differential Diagnosis.
Mas, Aymara; (...); Simon, Carlos
Meeting Abstract. 2020
Intraovarian injection of plasma rich in growth factors improves ovarian reserve and reproductive outcomes in women with diminished ovarian reserve
Herraiz, S.; (...); Munoz, M.
Meeting Abstract. 2022
INTRAOVARIAN INJECTION OF PLASMA RICH IN GROWTHFACTORS IMPROVES FOLLICLE GROWTH AND OOCYTE QUALITY AFTER COS IN AGED WOMEN WITH DIMINISHED OVARIAN RESERVE.
Herraiz, Sonia; (...); Munoz, Manuel
Meeting Abstract. 2023
Intra-ovarian injection of plasma rich in stem cell-secreted and platelet-enclosed factors to promote follicle rescue and reproductive outcomes in women with very low ovarian reserve
Molinaro, P.; (...); HERRAIZ, S.
Meeting Abstract. https://doi.org/10.1093/humrep/deae108.1114. 2024
Intraovarian PRP injection improves oocyte quality and early embryo development in mouse models of chemotherapy-induced diminished ovarian reserve.
Cozzolino, Mauro; (...); Herraiz, Sonia
Article. 10.18632/aging.206099. 2024
Is Axillary Assessment of Ductal Carcinoma In Situ of the Breast Necessary in All Cases?
Bellver G; (...); Ortega J
Article. 10.1016/j.jss.2021.10.006. 2022
Is Body Appreciation a Moderator of Women's Satisfaction and Distress with the Body Changes that Occur after Breast Cancer Surgery? A One-Year Longitudinal Study.
Marco-Salvador JH; (...); Ripoll Orts F
Article. 10.1017/SJP.2024.13. 2024
Kit Ligand Depletion Reverts the Positive Effects of Plasma Rich in Both Stem Cell-Secreted and Platelet-Enclosed Factors on Ovulation and Ovarian Niche
Buigues, Anna; (...); Herraiz, Sonia
Meeting Abstract. 2023
LH preserves oocyte-granulosa cell communication in mouse ovaries exposed to chemotherapy with alkylating agents
Castillo, LM; (...); Herraiz, S
Meeting Abstract. 2021
LH prevents follicular damage and preserves the meiotic potential of oocytes exposed to chemotherapy at the primordial stage
Castillo, LM; (...); Herraiz, S
Meeting Abstract. 2020
Live donor kidney transplantation. Situation analysis and roadmap.
de la Oliva Valentín M; (...); Domínguez-Gil B
Article. 10.1016/j.nefroe.2022.02.002. 2022
Mitochondrial enrichment in infertile patients: a review of different mitochondrial replacement therapies
Rodríguez-Varela C, Herraiz S, Labarta E
Review. 10.1177/26334941211023544. 2021
MITOCHONDRIAL FUNCTION AND OOCYTE QUALITY IMPROVED IN AN AGING MODEL BY INTRAOVARIAN ADMINISTRAION OF A COMBINATION OF STEM CELL-SECRETED- AND PLATELET-ENCLOSED GROWTH FACTORS
Marchante Cuevas, Maria; (...); Herraiz, Sonia
Meeting Abstract. 2022
Murine Oocyte Maturation and Developmental Competence Using Biocompatible Hydrogel Based on Decellularized Bovine Ovarian Cortex
Lopez, Rosalba; (...); Cervello, Irene
Meeting Abstract. 2022
New insights for fertility preservation by ovarian tissue cryopreservation and transplantation in pediatric cancer patients.
Editorial Material. 10.1016/j.fertnstert.2020.07.057. 2020
Nicotinamide mononucleotide (NMN) supplementation during germinal vesicle (GV) rescue could increase the total number of mature oocytes available in women of advanced maternal age (AMA)
Rodriguez Varela, C.; (...); Escriba, M. J.
Meeting Abstract. 10.1016/j.fertnstert.2022.08.427. 2024
Nicotinamide mononucleotide supplementation improves oocyte developmental competence in different ovarian damage conditions.
Ramirez-Martin, Noelia; (...); Herraiz, Sonia
Article. 10.1016/j.ajog.2025.02.006. 2025
Nicotinamide Mononucleotide Supplementation Improves Oocyte Quality in Chemotherapy Induced Ovarian Damage Mouse Models
Ramirez-Martin, Noelia; (...); Herraiz, Sonia
Meeting Abstract. 2023
Oncological outcomes of intraperitoneal chemotherapy in advanced ovarian cancer: BRCA mutation role.
Padilla-Iserte P; (...); Domingo S
Article. 10.1016/j.ejso.2024.108263. 2024
Optimizing ovarian tissue quality before cryopreservation: comparing outcomes of three decortication methods on stromal and follicular viability
Herraiz, S; (...); Diaz-Garcia, C
Article. 10.1016/j.fertnstert.2019.10.030. 2020
Oxidative stress and ovarian aging: from cellular mechanisms to diagnostics and treatment.
Ammar OF; (...); Fraire-Zamora JJ
Article. 10.1093/humrep/deae082. 2024
Pathways and factors regulated by bone marrow-derived stem cells in human ovarian tissue.
Buigues A; (...); Herraiz S
Article. 10.1016/j.fertnstert.2021.04.009. 2021
Plasma Enriched in Stem Cell Secreted Factors Improves Ovarian Function in a Mouse Model of Advanced Maternal Aged.
Marchante, M; (...); Herraiz, S
Meeting Abstract. 2021
Potential Molecules and Pathways Involved in Ovarian Rescue by Bone Marrow Derived Stem Cells in Human Ovarian Tissue.
Buigues, A; (...); Herraiz, S
Meeting Abstract. 2021
Rucaparib for PARP inhibitor-pretreated ovarian cancer: A GEICO retrospective subgroup analysis from the Spanish Rucaparib Access Program.
Yubero, Alfonso; (...); Gonzalez-Martin, Antonio
Case Reports. 10.1016/j.gore.2023.101211. 2023
Rucaparib in recurrent ovarian cancer: real-world experience from the rucaparib early access programme in Spain - A GEICO study
Yubero, Alfonso; (...); Gonzalez-Martin, Antonio
Article. 10.1186/s12885-022-10191-5. 2022
Sentinel Lymph Node Biopsy vs No Axillary Surgery in Patients With Small Breast Cancer and Negative Results on Ultrasonography of Axillary Lymph Nodes: The SOUND Randomized Clinical Trial.
Gentilini OD; (...); Veronesi P
Article. 10.1001/jamaoncol.2023.3759. 2023
SERUM P LEVELS MEASURED ON THE DAY OF EMBRYO TRANSFER IN FRESH IVF CYCLES yam OWN OOCYTES ARE NOT RELATED TO PREGNANCY OUTCOME.
Labarta, Elena; (...); Bosch, Ernesto
Meeting Abstract. 2022
SHORT-TERM ORAL SUPPLEMENTATION WITH NICOTINAMIDE MONONUCLEOTIDE RESTORES OOCYTE QUALITY IN CHEMOTHERAPY-INDUCED OVARIAN DAMAGE MOUSE MODELS
Buigues, Anna; (...); Herraiz, Sonia
Meeting Abstract. 2023
SINGLE CELL RNASEQ ANALYSES OF UTERINE FIBROIDS AND FIBROID-FREE MYOMETRIA REVEAL PREVIOUSLY UNIDENTIFIED CELL TYPE AND STATE.
Wang, WX; (...); Simon, C
Meeting Abstract. 10.1016/j.fertnstert.2019.07.1001. 2019
SINGLE CELL TRANSCRIPTOMES FROM UTERINE FIBROIDS AND FIBROID-FREE MYOMETRIUM ELUCIDATE MYOMETRIAL TUMORIGENESIS.
Wang, WX; (...); Simon, C
Meeting Abstract. 2020
Single intraovarian dose of stem cell- and platelet-secreted factors mitigates age-related ovarian infertility in a murine model.
Marchante, Maria; (...); Herraiz, Sonia
Article. 10.1016/j.ajog.2023.01.018. 2023
Stem Cell Paracrine Signaling for Treatment of Premature Ovarian Insufficiency.
Polonio AM, García-Velasco JA, Herraiz S
Review. 10.3389/fendo.2020.626322. 2021
Stem cell secreted factor therapy regenerates the ovarian niche and rescues follicles.
Buigues, Anna; (...); Herraiz, Sonia
Article. 10.1016/j.ajog.2021.01.023. 2021
Stem Cell Secreted Factors-Enriched Plasma Promotes DNA Repair and Protects Against Chemotherapy-Induced Cell Death in Ovarian Tissue.
Marchante, M; (...); Herraiz, S
Meeting Abstract. 2020
Strategies for breast cancer surgery during & after COVID-19 pandemic
Ashoor, A; (...); Veronesi, P
Meeting Abstract. 2021
Systemic changes induced by autologous stem cell ovarian transplant in plasma proteome of women with impaired ovarian reserves.
Buigues, Anna; (...); Herraiz, Sonia
Article. 10.18632/aging.205400. 2023
Telomere Length Maintenance of Granulosa Cells During Folliculogenesis in Humans
Chico-Sordo, Lucia; (...); Varela, Elisa
Meeting Abstract. 2023
Testosterone does not improve ovarian response in Bologna poor responders: a randomized controlled trial (TESTOPRIM).
Subira, Jessica; (...); Rubio Rubio, Jose Maria
Article. 10.1016/j.rbmo.2021.05.021. 2021
The 4-step ASCOT technique modifies the plasma proteome of patients with premature ovarian insufficiency to resemble that of normoresponder women
BUIGUES, A.; (...); HERRAIZ, S.
Meeting Abstract. https://doi.org/10.1093/humrep/deae108.1103. 2024
The cyto-protective effects of LH on ovarian reserve and female fertility during exposure to gonadotoxic alkylating agents in an adult mouse model.
Del Castillo LM; (...); Herraiz S
Article. 10.1093/humrep/deab165. 2021
The differential diagnoses of uterine leiomyomas and leiomyosarcomas using DNA and RNA sequencing
Mas, A; (...); Simon, C
Article. 10.1016/j.ajog.2019.05.018. 2019
The inaccuracy of LaFarge equations estimating the oxygen consumption in children under 3 years age.
Limón A; (...); Argente P
Article. 10.1016/j.redar.2019.07.008. 2019
The Use of Vaginal Lubricants and Ultrasound Gels Can have Deleterious Effects on Sperm Function.
Soriano, Maria Jose; (...); Rubio, Jose Maria
Article. 10.4103/jhrs.JHRS_128_18. 2021
THROMBOSPONDIN-1 DEPLETION SUPPRESSED FOLLICULAR GROWTH INDUCED BY STEM CELL SECRETED FACTORS-ENRICHED PLASMA ON CHEMOTHERAPY-DAMAGED MOUSE OVARIES
Buigues, Anna; (...); Herraiz, Sonia
Meeting Abstract. 2022
Transcriptomic landscape of granulosa cells and peripheral blood mononuclear cells in women with PCOS compared to young poor responders and women with normal response
Cozzolino, Mauro; (...); Seli, Emre
Article. 10.1093/humrep/deac069. 2022
Underlying mechanisms in clinical manifestations of polycystic ovarian morphology (PCOM) and PCOS women
Ramirez Martin, N.; (...); HERRAIZ, S.
Meeting Abstract. 2023
Underlying molecular mechanisms of Polycystic Ovary Syndrome and Morphology: focusing on the ovary
Ramirez Martin, N.; (...); HERRAIZ, S.
Meeting Abstract. https://doi.org/10.1093/humrep/deae108.936. 2024
Use of dopamine agonists to target angiogenesis in women with endometriosis.
Pellicer N; (...); Pellicer A
Review. 10.1093/humrep/deaa337. 2021
YOUNG WOMEN DIAGNOSED WITH DISTAL CANCER SHOW TELOMERE ALTERATIONS IN THE OVARY.
Chico-Sordo, Lucia; (...); Varela, Elisa
Meeting Abstract. 2021