SUSPENSIÓN DEL TRATAMIENTO ANTI-TNF EN PACIENTES CON ENFERMEDAD INFLAMATORIA INTESTINAL: ENSAYO CLÍNICO MULTICÉNTRICO, PROSPECTIVO Y ALEATORIZADO.
Datos básicos
- Protocolo:
- GIS-SUSANTI-TNF-2015
- EUDRACT:
- 2015-001410-10
- NCT:
- Centro:
- HOSPITAL UNIVERSITARI I POLITÈCNIC LA FE
- Año de incio:
- 2017
- Año de finalización:
- 2021
Documentos
- No hay documentos
Participantes
Financiadores - Promotores
Resultados del Ensayo Clínico
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Association between disease activity and quality of life in ulcerative colitis: Results from the CRONICA-UC study
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Impact of NADPH oxidase functional polymorphisms in acute myeloid leukemia induction chemotherapy
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Impact of novel polymorphisms related to cytotoxicity of cytarabine in the induction treatment of acute myeloid leukemia
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Individualized Prophylactic Treatment with Recombinant Factor VIII in Severe or Moderate Haemophilia a Patients. Association Between Pharmacokinetic Parameters and Clinical Variables
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Influence of cytarabine metabolic pathway polymorphisms in acute myeloid leukemia induction treatment
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Influence of pharmacokinetic/pharmacodynamic ratio on vancomycin treatment response in paediatric patients with Staphylococcus aureus bacteremia.
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Intestinal tuberculosis simulating Crohn's disease: Differential diagnosis.
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Intraperitoneal vancomycin in neonates during peritoneal dialysis: A case report
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Calafat, M; (...); ENEIDA Registry GETECCU
Meeting Abstract. 10.1093/ecco-jcc/jjy222.548. 2019
Long-term effectiveness and safety of vedolizumab (VDZ) in inflammatory bowel disease (IBD): Results from the Spanish ENEIDA Registry
Chaparro, M; (...); Gisbert, JP
Meeting Abstract. 2018
Long-Term Efficacy and Safety of Cyclosporine in a Cohort of Steroid-Refractory Acute Severe Ulcerative Colitis Patients from the ENEIDA Registry (1989-2013): A Nationwide Multicenter Study
Ordás I; (...); Esteve M
Article. 10.1038/ajg.2017.180. 2017
Long-term outcome of ulcerative colitis patients responders to cyclosporine in the biological era
Bastida, G; (...); Lobaton, T
Meeting Abstract. 2017
Long-Term Safety of In Utero Exposure to Anti-TNF alpha Drugs for the Treatment of Inflammatory Bowel Disease: Results from the Multicenter European TEDDY Study
Chaparro, M; (...); Gisbert, JP
Article. 10.1038/ajg.2017.501. 2018
Management and outcomes of patients with Crohn's disease with first vs multiple surgeries: results from the PRACTICROHN study
Iborra, M; (...); Domenech, E
Article. 10.1093/gastro/goz029. 2019
Management of acute severe ulcerative colitis in Spain: A nationwide clinical practice survey
Rodriguez-Lago, I; (...); Gisbert, JP
Article. 10.1016/j.gastrohep.2018.09.002. 2019
Metyrapone as treatment in the neonatal McCune-Albright syndrome
de Mingo, Carmen; (...); Garcia-Robles, Ana
Article. 10.1515/jpem-2020-0036. 2020
Monitoring coagulation factors during surgery. A systematic review
Eduardo Megias-Vericat, Juan; (...); Luis Poveda-Andres, Jose
Review. 10.7399/fh.11766. 2021
Monitoring the quality of the hospital pharmacoterapeutic process by sentinel patient program.
Fernandez-Megia, MJ; (...); Poveda Andrés JL
Article. 10.7399/fh.10793. 2018
Neuropsychological assessment and cortisol levels in biofluids from early Alzheimer's disease patients
Pena-Bautista, C.; (...); Chafer-Pericas, C.
Article. 10.1016/j.exger.2019.05.007. 2019
New screening approach for Alzheimer's disease risk assessment from urine lipid peroxidation compounds.
Peña-Bautista C; (...); Chafer-Pericas, C
Article. 10.1038/s41598-019-50837-2. 2019
Online course of pharmacokinetic monitoring in hemophilia with application in the clinical practice
Bonanad, S; (...); Poveda, JL
Meeting Abstract. 2018
Oxidative Stress in the Pathogenesis of Crohn's Disease and the Interconnection with Immunological Response, Microbiota, External Environmental Factors, and Epigenetics
Alemany-Cosme, E; (...); Beltran, B
Review. 10.3390/antiox10010064. 2021
Paracetamol vs. Ibuprofen in Preterm Infants With Hemodynamically Significant Patent Ductus Arteriosus: A Non-inferiority Randomized Clinical Trial Protocol
Garcia-Robles, Ana; (...); Carrascosa, MA
Article. 10.3389/fped.2020.00372. 2020
Pharmaceutical care to hospital outpatients during the COVID-19 pandemic. Telepharmacy
Margusino-Framiñán L; (...); Morillo-Verdugo R
Article. 10.7399/fh.11498. 2020
Pharmacogenetics of Metabolic Genes of Anthracyclines in Acute Myeloid Leukemia
Megias-Vericat, JE; (...); Montesinos, P
Review. 10.2174/1389200218666171101124931. 2018
Pharmacotherapy follow-up of patients under treatment with biologic agents for chronic inflammatory systemic conditions: an agreement among hospital pharmacists for the standardized collection of a minimum set of data.
Calleja Hernández MÁ; (...); Aragon, B
Article. 10.7399/fh.2017.41.1.10463. 2017
Phenotype and natural history of elderly onset inflammatory bowel disease: a multicentre, case-control study
Manosa, M; (...); Geteccu
Article. 10.1111/apt.14494. 2018
Physical Activity In Haemophilia: Hemorrhagic Risk And Factor Levels (myPKFiT)
Querol-Fuentes, F; (...); Bonanad, S
Meeting Abstract. 2017
Pilot evaluation of home delivery programme in haemophilia
Megias-Vericat, JE; (...); Poveda-Andres, JL
Article. 10.1111/jcpt.12718. 2018
PK-GUIDED SWITCH BETWEEN STANDARD HALF-LIFE AND EXTENDED HALF-LIFE FACTOR VIII PRODUCTS
Vericat, JEM; (...); Iorio, A
Meeting Abstract. 2020
Plasma alterations in cholinergic and serotonergic systems in early Alzheimer Disease: Diagnosis utility.
Peña-Bautista C; (...); Cháfer-Pericás C
Article. 10.1016/j.cca.2019.10.023. 2020
Plasma lipid peroxidation biomarkers for early and non-invasive Alzheimer Disease detection
Pena-Bautista, C; (...); Chafer-Pericas, C
Article. 10.1016/j.freeradbiomed.2018.06.038. 2018
Plasma Oncostatin M, TNF-a, IL-7, and IL-13 Network Predicts Crohn's Disease Response to Infliximab, as Assessed by Calprotectin Log Drop.
Mateos B; (...); Beltrán B
Article. 10.1159/000508069. 2020
Possible role of chondroitin sulphate and glucosamine for primary prevention of colorectal cancer. Results from the MCC-Spain study
Ibanez-Sanz, Gemma; (...); Moreno, Victor
Article. 10.1038/s41598-018-20349-6. 2018
Pre and post intervention study of antiblastic drugs contamination surface levels at a Pharmacy Department Compounding Area using a closed system drug transfer device and a decontamination process
Valero, S; (...); Poveda, JL
Article. 10.1016/j.yrtph.2018.03.001. 2018
PRELIMINAR STUDY OF THERAPY ADHERENCE CONTROLLED BY PRESCRIPTION OF MEDICATION AND SELF-PERCEPTION ADHERENCE OF INFLAMMATORY CHRONIC DISEASE PATIENTS
Garcia, EG; (...); Ivorra, JAR
Meeting Abstract. 10.1136/annrheumdis-2019-eular.5937. 2019
Preparación y administración de perfusiones de insulina en neonatología: Encuesta nacional.
García-Robles A; (...); Aguar-Carrascosa M
Letter. 10.1016/j.anpedi.2020.06.008. 2021
Prevalence, features and outcomes of splachnic vein thrombosis in inflammatory bowel disease. A nationwide, retrospective study from the ENEIDA registry
Masnou, H; (...); Eneida-GETECCU Registry
Meeting Abstract. 2020
Primary prevention of post-operative recurrence of Crohn's disease with anti-TNF agents in real life. Preliminary data from the Spanish ENEIDA registry
Canete, F; (...); Domenech, E
Meeting Abstract. 2018
Proactive therapeutic drug monitoring and pharmacogenetic analysis in inflammatory bowel disease: A systematic review
Ballesta-Lopez, Octavio; (...); Luis Poveda-Andres, Jose
Review. 10.7399/fh.11780. 2021
Prostaglandin Injection After Arterial Compromise Related to Hyaluronic Acid Filler
Megias-Vericat, JE; (...); Poveda, JL
Letter. 10.1097/DSS.0000000000001046. 2017
Quality of life during one year of postoperative prophylactic drug therapy after intestinal resection in Crohn's patients: Results of the APPRECIA trial
Taxonera, C; (...); Nos, P
Article. 10.1016/j.dld.2019.01.002. 2019
Quantification of physical activity in adult patients with haemophilic arthropathy in prophylaxis treatment using a fitness tracker
Perez-Alenda, S; (...); Querol, F
Letter. 10.1111/hae.13388. 2018
Real-life experience with 4 years of golimumab persistence in ulcerative colitis patients.
Article. 10.1038/s41598-020-73577-0. 2020
Real-life experience with long-term maintenance of golimumab in ulcerative colitis patients
Meeting Abstract. 10.1093/ecco-jcc/jjy222.683. 2019
Real-world long-term effectiveness of ustekinumab in Crohn's disease: results from the ENEIDA registry
Article. 10.1111/apt.15958. 2020
Real-world long-term effectiveness of ustekinumab in Crohn's disease: Results from the ENEIDA registry
Iborra Colomino, M. I.; (...); Nos, P.
Meeting Abstract. 2020
Real-world short-term effectiveness of ustekinumab in 305 patients with Crohn's disease: results from the ENEIDA registry
Iborra, M; (...); Chaparro, M
Article. 10.1111/apt.15371. 2019
Real-world short-term effectiveness of ustekinumab in Crohn's disease: Results from the ENEIDA Registry
Meeting Abstract. 10.1093/ecco-jcc/jjy222.629. 2019
Recommendations by the Spanish Working Group on Crohn's Disease and Ulcerative Colitis (GETECCU) on the treatment of patients with inflammatory bowel disease associated with spondyloarthritis
Gonzalez-Lama, Y; (...); Gomollon, F
Article. 10.1016/j.gastrohep.2020.01.005. 2020
Recommendations of the Crohn's Disease and Ulcerative Colitis Spanish Working Group (GETECCU) for the treatment of perianal fistulas of Crohn's disease.
Boscá MM; (...); Hinojosa J
Review. 10.1016/j.gastrohep.2019.09.012. 2020
Recommendations of the Spanish Working Group on Crohn's Disease and Ulcerative Colitis (GETECCU) and the Association of Crohn's Disease and Ulcerative Colitis Patients (ACCU) in the management of psychological problems in Inflammatory Bowel Disease patients
Barreiro-de Acosta, M; (...); Gisbert, JP
Review. 10.1016/j.gastrohep.2017.10.003. 2018
Recommendations of the Spanish Working Group on Crohn's Disease and Ulcerative Colitis (GETECCU) on pouchitis in ulcerative colitis. Part 1: Epidemiology, diagnosis and prognosis.
Barreiro-de Acosta M; (...); Nos P
Editorial Material. 10.1016/j.gastrohep.2019.08.001. 2019
Recommendations of the Spanish Working Group on Crohn's Disease and Ulcerative Colitis (GETECCU) on pouchitis in ulcerative colitis. Part 2: Treatment.
Barreiro-de Acosta M; (...); Nos P
Article. 10.1016/j.gastrohep.2020.04.004. 2020
Recommendations of the Spanish Working Group on Crohn's Disease and Ulcerative Colitis (GETECCU) on the monitoring, prevention and treatment of post-operative recurrence in Crohn's disease
Domènech E; (...); Mañosa M
Review. 10.1016/j.gastrohep.2017.05.005. 2017
Recommendations of the Spanish Working Group on Crohn's Disease and Ulcerative Colitis (GETECCU) on the use of tiopurines in inflammatory bowel disease
Berrnejo, F; (...); Lopez-Sanroman, A
Review. 10.1016/j.gastrohep.2017.11.007. 2018
Recommendations of the Spanish Working Group on Crohn's Disease and Ulcerative Colitis (GETECCU) on the utility of the determination of faecal calprotectin in inflammatory bowel disease
Guardiola, J; (...); Representacion GETECCU
Review. 10.1016/j.gastrohep.2018.05.029. 2018
Reduction in alert fatigue in an assisted electronic prescribing system, through the Lean Six Sigma methodology.
Cuéllar Monreal MJ; (...); Poveda Andrés JL
Article. 10.7399/fh.2017.41.1.10434. 2017
Regression of a giant pseudopolyp in a patient with colonic Crohn's disease after therapy with infliximab.
Sánchez Melgarejo JF; (...); Nos P
Article. 10.17235/reed.2019.6252/2019. 2019
Re-induction With Intravenous Ustekinumab in Patients With Crohn's Disease and a Loss of Response to This Therapy.
Bermejo F; (...); Guerra I
Article. 10.1093/ibd/izab015. 2021
Relevance of dynamic studies with magnetic resonance enterography in Crohn's disease.
Pous S; (...); Nos P
Article. 10.1016/j.gastrohep.2019.11.010. 2020
Reviewing the therapeutic role of budesonide in Crohn's disease
Lopez-Sanroman, A; (...); Domenech, E
Review. 10.1016/j.gastrohep.2018.05.013. 2018
Risk of immunomediated adverse events or secondary loss of response to infliximab in elderly patients with inflammatory bowel disease: a cohort study of the ENEIDA registry
Calafat, M; (...); Domenech, E
Meeting Abstract. 10.1093/ecco-jcc/jjy222.561. 2019
Risk of postoperative morbidity in patients having bowel resection for colonic Crohn's disease
Iesalnieks I; (...); El-Hussuna A
Article. 10.1007/s10151-018-1904-0. 2018
Salvage therapy with topical posaconazole in lung transplant recipients with invasive Scedosporium infection.
Article. 10.1111/ajt.14580. 2018
Secondary Haemophagocytic Syndrome and Overlapping Immune Reconstitution Syndrome: Life-Threatening Complications of Anti-TNF-alpha Treatment for Crohn's Disease
Saez-Gonzalez, E; (...); Beltran, B
Letter. 10.1038/s41395-018-0420-1. 2019
Secukinumab-induced ulcerative colitis: opening Pandora's box of immunity
Fernandez-de La Varg, M; (...); Paz, GB
Letter. 10.1016/j.gastrohep.2019.12.004. 2020
SEFH National Survey-2019: general characteristics, staffing, material resources and information systems in Spain's hospital pharmacy departments.
Pérez-Encinas M; (...); Calleja-Hernández MÁ
Article. 10.7399/fh.11565. 2020
Serial Tuberculin Skin Tests Improve the Detection of Latent Tuberculosis Infection in Patients With Inflammatory Bowel Disease
Taxonera, C; (...); CONVERT Study Grp GETECCU
Article. 10.1093/ecco-jcc/jjy104. 2018
Serum Adalimumab Levels Predict Successful Remission and Safe Deintensification in Inflammatory Bowel Disease Patients in Clinical Practice
Aguas Peris M; (...); Nos, P
Article. 10.1097/MIB.0000000000001182. 2017
Serum adalimumab levels predict successful remission and safe de-intensification in inflammatory bowel disease patients in clinical practice
Meeting Abstract. 2017
Short-term effectiveness of golimumab for ulcerative colitis: Observational multicenter study
Bosca-Watts, MM; (...); Paredes, JM
Article. 10.3748/wjg.v22.i47.10432. 2016
Should professionals provide their patients with digital health training resources?
Piudo, AE; (...); Marcos, NM
Meeting Abstract. 2020
Skin injuries associated with biological therapy in inflammatory bowel disease: beyond psoriasis.
Mínguez Sabater A; (...); Bastida G
Article. 10.1016/j.gastrohep.2020.09.003. 2022
Specific plasma micro-RNA profiles for prediction of recurrence in Crohn's disease in pre-surgery and established recurrence scenarios
Moret, I; (...); Beltran, B
Meeting Abstract. 2020
Standardization of the homogeneous mobility shift assay protocol for evaluation of anti-infliximab antibodies. Application of the method to Crohn's disease patients treated with infliximab
Hernandez-Breijo, B; (...); Guijarro, LG
Article. 10.1016/j.bcp.2016.019. 2016
Stopping azathioprine in monotherapy after very prolonged remission in inflammatory bowel disease patients: Novel relapse risk factors
Meeting Abstract. 2018
Surgical and hospital admission in adults newly diagnosed with inflammatory bowel disease (IBD) in the biological era in Spain: Results of the nationwide EpidemIBD study of GETECCU
Chaparro, M; (...); EpidemIBD Group
Meeting Abstract. 2018
Survey of adherence to treatment in inflammatory bowel disease. ENADEII study.
Alonso-Abreu I; (...); Quintero-Carrión E
Article. 10.1016/j.gastrohep.2019.10.007. 2020
Survey of adherence to treatment in inflammatory bowel disease: ENADEII STUDY
Abreu, IA; (...); GETECCU
Meeting Abstract. 2019
Switching to a Second Thiopurine in Adult and Elderly Patients With Inflammatory Bowel Disease: A Nationwide Study From the ENEIDA Registry.
Calafat M; (...); Domènech E
Article. 10.1093/ecco-jcc/jjaa055. 2020
Telemedicine in the treatment of patients with inflammatory bowel disease
Review. 10.1016/j.gastrohep.2017.07.001. 2017
Telemonitoring of Crohn's Disease and Ulcerative Colitis (TECCU): Cost-Effectiveness Analysis.
Del Hoyo J; (...); Aguas M
Article. 10.2196/15505. 2019
The availability of anti-TNF agents is associated with reduced early surgical requirements in Crohn's disease but not in ulcerative colitis. A nationwide study from the Eneida registry
Guasch, M; (...); Domenech, E
Meeting Abstract. 2018
The ENEIDA registry (Nationwide study on genetic and environmental determinants of inflammatory bowel disease) by GETECCU: Design, monitoring and functions.
Zabana Y; (...); Domènech E
Article. 10.1016/j.gastrohep.2020.05.007. 2020
The Female Sexual Function Index to assess patients with moderate to severe vulvar lichen sclerosus.
Gutierrez-Ontalvilla P; (...); Vicente D
Letter. 10.1684/ejd.2019.3580. 2019
The Harvey-Bradshaw Index Adapted to a Mobile Application Compared with In-Clinic Assessment: The MediCrohn Study.
Echarri A; (...); Muñiz J
Article. 10.1089/tmj.2018.0264. 2020
The initiation of thiopurines in elderly patients with inflammatory bowel disease is associated with an increased risk of adverse effects: a case-control study of the ENEIDA registry
Calafat, M; (...); Domenech, E
Meeting Abstract. 2018
The view of experts on initiatives to be undertaken to promote equity in the access to orphan drugs and specialised care for rare diseases in Spain: A Delphi consensus
Torrent-Farnell, J; (...); Lizan, L
Article. 10.1016/j.healthpol.2018.03.002. 2018
Tofacitinib in Ulcerative Colitis: Real-world Evidence From the ENEIDA Registry.
Chaparro M; (...); Gisbert JP
Article. 10.1093/ecco-jcc/jjaa145. 2021
Topiramate pharmacokinetics in neonates undergoing therapeutic hypothermia and proposal of an optimised dosing schedule.
Marques MR; (...); Mangas-Sanjuan V
Article. 10.1111/apa.14944. 2020
Towards a symbiotic relationship between big data, artificial intelligence, and hospital pharmacy
Del Rio-Bermudez, C; (...); Poveda, JL
Editorial Material. 10.1186/s40545-020-00276-6. 2020
Undetectable levels of adalimumab in clinical practice: Should we say goodbye to the drug?
Bejar, S; (...); Mateu, PN
Meeting Abstract. 2020
Use and handling safety of Mini-Spike 2 (R) chemo and puresite for safe chemotherapy compounding in a hospital pharmacy
Garcia, SV; (...); Andres, JLP
Article. 10.1016/j.yrtph.2018.10.002. 2018
USE OF CAPLACIZUMAB IN THE ACQUIRED THROMBOTIC THROMBOCYTOPENIC PURPURA
Dominguez Hernandez, L.; (...); Gomez Segui, I
Meeting Abstract. 2019
Use of Magnetic Resonance Index of Activity (MaRIA) in the preoperative assessment of small bowel Crohn's disease.
Pous-Serrano, S; (...); Garcia-Granero, E
Article. 10.1016/j.ciresp.2019.06.018. 2019
Use of mycophenolate mofetil in inflammatory bowel disease: results from the ENEIDA registry
Camba, AH; (...); Ramos, L
Meeting Abstract. 2020
Usefulness of monitoring antitumor necrosis factor serum levels during the induction phase in patients with Crohn's disease
Chaparro, M; (...); Gisbert, JP
Article. 10.1097/MEG.0000000000001706. 2020
Vedolizumab, an adequate option in medically refractory and thiopurine-intolerant inflammatory bowel disease patients
Meeting Abstract. 2018
Vedolizumab, an option in patients with inflammatory bowel disease intolerant to thiopurines and refractory to biological agents
Article. 10.1016/j.gastrohep.2018.06.001. 2018
Withdrawal of Azathioprine in Inflammatory Bowel Disease Patients Who Sustain Remission: New Risk Factors for Relapse
Article. 10.1007/s10620-018-5429-1. 2019