DESARROLLO DE INHIBIDORES EN PACIENTES NO TRATADOS PREVIAMENTE (PUP) O EN PACIENTES MINIMAMENTE TRATADOS CON COMPONENTES SANGUINEOS (MBCTP) AL SER EXPUESTOS A CONCENTRADOS DE DERIVADOS PLASMATICOS CON FACTOR DE VON WILLEBRAND CONTENIENDO FACTOR VIII (VWF/ FVIII) O A CONCENTRADOS CON FACTOR VIII RECOMBINANTE (RFVIII): ENSAYO CLINICO INDEPENDIENTE, INTERNAICONAL, MULTICENTRICO, PROSPECTIVO, CONTROLADO, ALEAOTRIZADO Y ABIERTO.

Datos básicos

Código:
ABB-09-001
Protocolo:
ABB-09-001
EUDRACT:
2009-011186-88
NCT:
Centro:
Dotación:
Año de incio:
Año de finalización:
ENSAYO CLÍNICO

Documentos

  • No hay documentos

Participantes

Grupos

Financiadores - Promotores

FOND CEN EMOFILIA E TROMBOSI ANGELO BIANCHI BONOMI

Resultados del Ensayo Clínico


[Translated article] Pharmacokinetic-guided switching from standard half-life factor VIII to extended half-life pegylated factor VIII in haemophilia A therapy in clinical practice.

Chovi-Trull, Maria; (...); Andres, Jose Luis Poveda

Article. 10.1016/j.farma.2024.12.007. 2025


A post hoc comparative real-world analysis of HEAD-US score for joint health assessment of patients with severe haemophilia A and B in Spain

Alvarez-Roman, Maria Teresa; (...); Kim, Hae Kyung

Article. 10.1111/hae.14924. 2024


A Randomized Trial of Factor VIII and Neutralizing Antibodies in Hemophilia A

Peyvandi F; (...); Rosendaal FR

Article. 10.1056/NEJMoa1516437. 2016

  • Open Access.

A simplified assay for the quantification of circulating activated protein C

Martos L; (...); Medina P

Article. 10.1016/j.cca.2016.05.025. 2016


a2-Macroglobulin is a significant in vivo inhibitor of activated protein C and low levels of APC:a2M are associated with venous thromboembolism

Navarro S; (...); Medina P

Article. 2018


ACUTE MYELOID LEUKEMIA IN PATIENTS 70 AND ABOVE. AZACITIDINE VERSUS INTENSIVE CHEMOTHERAPY

De La Fuente, A.; (...); Ramos, F.

Meeting Abstract. 2014

  • Open Access.

Adherence to prophylaxis and quality of life in children and adolescents with severe haemophilia A

García-Dasí M; (...); García-Talavera JA

Article. 10.1111/hae.12618. 2015


Adherence to prophylaxis in adult patients with severe haemophilia A

Bonanad, S; (...); Alvarez, M

Meeting Abstract. 2019


Adherence to prophylaxis in adult patients with severe haemophilia A

Bonanad, S; (...); Alvarez, MP

Article. 10.1111/hae.14039. 2020


Adverse effects after a single moderate-volume strong-intensity strength training session in patients with severe hemophilia: feasibility and safety study

Querol-Fuentes, F; (...); Bonanad, S

Meeting Abstract. 2018


alpha(2)-Macroglobulin Is a Significant In Vivo Inhibitor of Activated Protein C and Low APC: alpha M-2 Levels Are Associated with Venous Thromboembolism

Martos, L; (...); Medina, P

Article. 10.1055/s-0038-1629902. 2018

  • Open Access.

Allogeneic hematopoietic cell transplantation in an adult patient with Glanzmann thrombasthenia.

Cid, AR; (...); Sanz, MA

Article. 10.1002/ccr3.1206. 2017

  • Open Access.

ANALYSIS OF THE USE OF MOBILE APPLICATIONS IN PATIENTS WITH HAEMOPHILIA AFTER TWO YEARS OF FOLLOW-UP

Megias Vericat, J. E.; (...); Bonanad Boix, S.

Meeting Abstract. 2019

  • Open Access.

Assessment of Kinect V2 for elbow range of motion estimation in people with haemophilia using an angle correction model

Mateo, F; (...); Perez-Alenda, S

Article. 10.1111/hae.13744. 2019


Association of Vitamin K and Non-Vitamin K Oral Anticoagulant Use and Cancer Incidence in Atrial Fibrillation Patients

Iftimi AA; (...); Sanfélix-Gimeno G

Article. 10.1002/cpt.2362. 2021

  • Open Access.

Azacitidine in older patients with acute myeloid leukemia (AML). Results from the ALMA study according to the MRC risk index score.

Falantes, Jose F.; (...); Ramos, Fernando

Meeting Abstract. 2015


Bayesian pharmacokinetic individualization of prophylaxis with recombinant factor VIII in severe or moderate hemophilia A

Megias-Vericat, JE; (...); Bonanad, S

Meeting Abstract. 2018


Bayesian pharmacokinetic-guided prophylaxis with recombinant factor VIII in severe or moderate haemophilia A

Megias-Vericat, JE; (...); Poveda, JL

Article. 10.1016/j.thromres.2018.12.027. 2019


Benefits of Ehl Factor VIII Replacement Therapy in Hemophilia: Observations on Coverage, Physical Activity and Phisiotherapy

Querol, Felipe; (...); Bonanad Boix, Santiago

Meeting Abstract. 10.1182/blood-2019-125651. 2019


Benefits of physical activity self-monitoring in patients with haemophilia: a prospective study with one-year follow-up.

Pérez-Alenda S; (...); Núñez-Cortés R

Article. 10.1111/hae.14988. 2024

  • Open Access.

Bladder cancer patients have increased NETosis and impaired DNaseI-mediated NET degradation that can be therapeutically restored in vitro.

Herranz R; (...); Medina P

Article. 10.3389/fimmu.2023.1171065. 2023

  • Open Access.

Case-Control Pilot Study of the Immune Modulating Effect of FEIBA (R) on Patients with Haemophilia a and Inhibitors

Fernandez Bello, Ihosvany; (...); Butta, Nora

Meeting Abstract. 2015


Cerebral calcium embolism.

Asensi Canto, Pedro; (...); Bonanad Boix, Santiago

Article. 10.1002/ccr3.4962. 2022

  • Open Access.

Clinical and molecular characterization by next generation sequencing of Spanish patients affected by congenital deficiencies of fibrinogen.

Moret, A; (...); Bonanad, S

Letter. 10.1016/j.thromres.2019.06.015. 2019


CLINICAL AND MOLECULAR CHARACTERIZATION BY SEQUENCING OF NEW GENERATION OF PATIENTS AFFECTED BY FIBRINOGEN CONGENITAL DEFICIENCIES

Moret, A.; (...); Bonanad, S.

Meeting Abstract. 2019

  • Open Access.

Clinical benefits of a Bayesian model for plasma-derived factor VIII/VWF after one year of pharmacokinetic-guided prophylaxis in severe/moderate hemophilia A patients

Megias-Vericat, JE; (...); Poveda, JL

Article. 10.1016/j.thromres.2021.07.009. 2021


Clinical Outcomes of 217 Patients with Acute Erythroleukemia According to Treatment Type and Line: A Retrospective Multinational Study

Almeida AM; (...); Pleyer L

Article. 10.3390/ijms18040837. 2017

  • Open Access.

CLINICAL OUTCOMES OF ACUTE ERYTHROLEUKEMIA TREATED WITH AZACITIDINE: A RETROSPECTIVE MULTICENTER STUDY

Almeida, A.; (...); Pleyer, L.

Meeting Abstract. 2015

  • Open Access.

CLINICAL VALIDATION OF THE SPECIFIC POPULATION MODEL OF FACTOR VIII/FVW PLASMA USING WAPPS-HEMO

Megias Vericat, J. E.; (...); Poveda, A. J. L.

Meeting Abstract. 2019

  • Open Access.

Clinical, pharmacokinetic and economic analysis of the first switch to an extended half-life factor IX (albutrepenonacog alfa, rFIX-FP) in Spain.

Rodríguez López M; (...); Bonanad S

Article. 10.1136/bcr-2019-234142. 2020


Collaborative model of home delivery program in haemophilia through an association of patients

Megias-Vericat, JE; (...); Bonanad, S

Meeting Abstract. 2018


Comorbidities in Patients With Hemophilia: Changes in Joints and its Correlation with Bone Mineral Density

Perez-Alenda, S.; (...); Querol, F.

Meeting Abstract. 2015


Comparative analysis of Hemophilia Early Arthropathy Detection with Ultrasound (HEAD-US) scores in persons with nonsevere hemophilia A and B reveals a high degree of joint damage in both disease types

Jimenez-Yuste, Victor; (...); Kim, Hae Kyung

Letter. 10.1016/j.rpth.2023.102207. 2023

  • Open Access.

Comparison of pharmacokinetic estimates using generic and specific population pharmacokinetic models of plasma-derived factor VIII/VWF using WAPPS-Hemo

Megias-Vericat, JE; (...); Poveda, JL

Meeting Abstract. 2020


COMPREHENSIVE LONG-TERM FOLLOW-UP OF PAROXYSMAL NOCTURNAL HEMOGLOBINURIA: A REPORT FROM A SINGLE CENTRE

Sempere, A.; (...); Jarque, I.

Meeting Abstract. 2016

  • Open Access.

Comprehensive Screening of Genetic Variants in the Coding Region of F8 in Severe Hemophilia A Reveals a Relationship with Disease Severity in a Colombian Cohort.

Sarmiento Doncel, Samuel; (...); Lopez Guerrero, Jose A

Article. 10.3390/life14081041. 2024

  • Open Access.

Consensus Statement on Hemostatic Management, Anticoagulation, and Antiplatelet Therapy in Liver Transplantation.

Montalvá E; (...); Colmenero J

Article. 10.1097/TP.0000000000004014. 2022

  • Open Access.

Considering Bone Marrow Blasts from Nonerythroid Cells Improves the Prognostic Evaluation of Myelodysplastic Syndromes with Ring Sideroblasts

Arenillas, Leonor; (...); Florensa, Lourdes

Meeting Abstract. 2016


Considering Bone Marrow Blasts from Nonerythroid Cellularity Improves the Prognostic Evaluation of MDS in the Context of IPSS-R and Permits a Better Risk Assessment of MDS Patients Classified into the Intermediate Risk Category

Calvo, Xavier; (...); Florensa, Lourdes

Meeting Abstract. 10.1182/blood.V128.22.3185.3185. 2016


Considering Bone Marrow Blasts From Nonerythroid Cellularity Improves the Prognostic Evaluation of Myelodysplastic Syndromes

Arenillas L; (...); Florensa L

Article. 10.1200/JCO.2016.66.9705. 2016


Correction to: Routine clinical care data for population pharmacokinetic modeling: the case for Fanhdi/Alphanate in hemophilia A patients.

Chelle P; (...); Edginton A

Article. 10.1007/s10928-019-09647-2. 2019

  • Open Access.

Costs of the management of hemophilia A with inhibitors in Spain

Bonanad, S; (...); Gonzalez-Dominguez, A

Article. 10.33393/grhta.2021.2234. 2021

  • Open Access.

Cross-sectional comparative study of pharmacokinetics and efficacy between sucrose-formulated recombinant factor VIII (Kogenate (R)) and BAY 81-8973 (KovaltryA (R)) in patients with severe or moderate haemophilia A in prophylaxis

Megias-Vericat, JE; (...); Poveda, JL

Letter. 10.1111/hae.13733. 2019


Cross-Sectional Comparative Study of PK-Guided Switch between Standard Half-Life and Extended Half-Life Factor VIII Products

Eduardo Megias, Juan; (...); Iorio, Alfonso

Meeting Abstract. 10.1182/blood-2019-127946. 2019

  • Open Access.

Challenges, questions and opportunities with regard to the new relationship between clinical practice and the haemostasis laboratory: the path towards personalized medicine.

Cid AR

Article. 10.1097/MBC.0000000000001091. 2021


Delving into the clinical impact of NETs in pediatric cancer.

Benavent N; (...); Medina P

Article. 10.1038/s41390-024-03437-4. 2024


DESCRIPTIVE STUDY OF THE RECORD OF THROMBOTIC MICROANGIOPATHY IN A SINGLE CENTRE

Romero Dominguez, S.; (...); Sanz Alonso, M. A.

Meeting Abstract. 2015

  • Open Access.

Determinants of bleeding before and during immune tolerance in 222 boys with severe hemophilia A and inhibitors >5 BU.

Fischer K; (...); Königs C

Article. 10.1182/bloodadvances.2023011442. 2024

  • Open Access.

Development and psychometric validation of a brief comprehensive health status assessment scale in older patients with hematological malignancies: The GAH Scale

Bonanad S; (...); GAH Group

Article. 10.1016/j.jgo.2015.03.003. 2015


Development and testing of a mobile app for systematic collection of patient-reported outcomes (PROs) in patients with hemophilia.

Megias-Vericat, J E; (...); Poveda Andres, J L

Letter. 10.1016/j.thromres.2024.109122. 2024


Development and Validation of a Population-Pharmacokinetic Model for Rurioctacog Alfa Pegol (Adynovate ): A Report on Behalf of the WAPPS-Hemo Investigators Ad Hoc Subgroup.

Chelle P; (...); Iorio A

Article. 10.1007/s40262-019-00809-6. 2020


DIAGNOSIS AND MANAGEMENT OF HEMARTHROSIS AND HAEMOPHILIC ARTHROPATHY USING UNIFIED CLINICAL AND ULTRASOUND CRITERIA: PRELIMINARY RESULTS

Chimeno-Hernandez, A; (...); Querol, F

Meeting Abstract. 2021


DIAGNOSIS OF JOINT BLEEDS: PREDICTIVE MODELING BASED ON PATIENT-REPORTED SYMPTOMS

Goldmann, G.; (...); Tiede, A.

Meeting Abstract. 2023


Effect of monitoring daily physical activity on quality of life in adult patients with haemophilic arthropathy

Perez-Alenda, Sofia; (...); Carrasco, Juan J.

Meeting Abstract. 2018


Effect of Prophylaxis with Activated Prothrombin Complex Concentrate on Anamnestic Response of Patients with Severe Haemophilia A and Inhibitors

Fernandez-Bello, I.; (...); Jimenez-Yuste, V.

Meeting Abstract. 2016


Effect of radiosynoviorthesis on the progression of arthropathy and haemarthrosis reduction in haemophilic patients

Querol-Giner, M.; (...); Querol, F.

Article. 10.1111/hae.13326. 2017


Effectiveness of progressive moderate-vigorous intensity elastic resistance training on quality of life and perceived functional abilities in people with haemophilia: secondary analysis of a randomized controlled trial.

Cruz-Montecinos C; (...); Calatayud J

Article. 10.1111/ejh.13900. 2022

  • Open Access.

Effects of a non-pharmacological approach for chronic pain management in patients with haemophilia: efficacy of cognitive-behavioural therapy associated with physiotherapy.

García-Dasí M; (...); Bonanad S

Article. 10.1111/hae.14284. 2021


EFFECTS OF MULTIMODAL EXERCISES PROGRAM ON BALANCE, FUNCTIONALITY, RISK OF FALLS AND STRENGTH IN PEOPLE WITH HAEMOPHILIA

Chimeno-Hernandez, A.; (...); Querol, F.

Article. 2022


Efficacy and safety evaluation of Fanhdi ® , a plasma-derived factor VIII/ von Willebrand factor concentrate, in Von Willebrand's disease patients undergoing surgery or invasive procedures: A prospective clinical study.

Jimenez-Yuste, Victor; (...); Paez, Antonio

Letter. 10.1111/hae.14453. 2022

  • Open Access.

EFFICACY AND SAFETY OF EPTACOG BETA (RECOMBINANT HUMAN FVIIA) ACCORDING TO AGE IN PERSONS WITH HAEMOPHILIA A/B WITH INHIBITORS UNDERGOING SURGICAL PROCEDURES

Miesbach, W.; (...); Mahlangu, J.

Meeting Abstract. 2023


eLearning of pharmacokinetic monitoring in hemophilia with application in the clinical practice

Bonanad, S; (...); Megias-Vericat, JE

Meeting Abstract. 2018


Electromyographic and Safety Comparisons of Common Lower Limb Rehabilitation Exercises for People With Hemophilia.

Calatayud J; (...); Casaña J

Article. 10.1093/ptj/pzz146. 2020


Emicizumab-induced photosensitivity.

Asensi Canto, Pedro; (...); Haya Guaita, Saturnino

Article. 10.1055/s-0042-1749092. 2022


Enumerating bone marrow blasts from nonerythroid cellularity improves outcome prediction in myelodysplastic syndromes and permits a better definition of the intermediate risk category of the Revised International Prognostic Scoring System (IPSS-R)

Calvo, X; (...); Florensa, L

Article. 10.1002/ajh.24732. 2017

  • Open Access.

EPTACOG BETA EFFICACY AT 24 HOURS POSTINFUSION FOR MILD OR MODERATE BLEEDS IN INDIVIDUALS WITH HEMOPHILIA A OR B AND INHIBITORS

Boggio, Lisa; (...); Escobar, Miguel

Meeting Abstract. 2023


Erythroleukemia shares biological features and outcome with myelodysplastic syndromes with excess blasts: a rationale for its inclusion into future classifications of myelodysplastic syndromes

Calvo X; (...); Florensa L

Article. 10.1038/modpathol.2016.146. 2016

  • Open Access.

Experience of Home Delivery Program in Haemophilia Through an Association of Patients

Megias Vericat, J. E.; (...); Bonanad Boix, S.

Meeting Abstract. 2017


Factor XIII deficiency in two Spanish families with a novel variant in gene F13A1 detected by next-generation sequencing; symptoms and clinical management.

Moret A; (...); Bonanad S

Article. 10.1007/s11239-020-02065-z. 2020


Feasibility, safety and muscle activity during flywheel vs traditional strength training in adult patients with severe haemophilia.

Calatayud J; (...); Casaña J

Article. 10.1111/hae.14170. 2020


Further psychometric validation of the GAH scale: Responsiveness and effect size

Cruz-Jentoft, AJ; (...); GAH Group

Article. 10.1016/j.jgo.2016.12.008. 2017


GAH SCALE PREDICTS TREATMENT TOLERABILITY IN OLDER PATIENTS (> 65 YEARS) DIAGNOSED WITH HEMATOLOGICAL MALIGNANCIES

Bonanad, S; (...); de la Rubia, J

Meeting Abstract. 2017

  • Open Access.

Gait analysis by means of accelerometry in patients with haemophilic arthropathy

Carrasco, Juan J.; (...); Querol, Felipe

Meeting Abstract. 2016


Geriatric assessment in hematology scale predicts treatment tolerability in older patients diagnosed with hematological malignancies: The RETROGAH study.

de la Rubia J; (...); Bonanad, Santiago

Article. 10.1016/j.jgo.2022.10.016. 2022

  • Open Access.

Haemophilic arthropathy: basic protocols for clinical examination and imaging.

Querol, F.; (...); Perez-Alenda, S.

Article. 10.1097/MBC.0000000000001215. 2023


HaemoPREF: Further evaluation of patient perception and preference for treatment in a real world setting

Bonanad, S; (...); Brohan, E

Article. 10.1111/hae.13321. 2017


Haemotrack: Musculoskeletal management in haemophilia with physiotherapist-driven digital solutions

Perez-Alenda, Sofia; (...); Aguilar-Rodriguez, Marta

Meeting Abstract. 2024


HemoKinect: A Microsoft Kinect V2 Based Exergaming Software to Supervise Physical Exercise of Patients with Hemophilia

Mateo, F; (...); Perez-Alenda, S

Article. 10.3390/s18082439. 2018

  • Open Access.

HIDDEN MDS: A PROSPECTIVE STUDY TO CONFIRM OR EXCLUDE MDS IN PATIENTS WITH ANEMIA OF UNCERTAIN ETIOLOGY

Bastida Bermejo, J. M.; (...); Diez-Campelo, M.

Meeting Abstract. 2016

  • Open Access.

HIDDEN MDS: A PROSPECTIVE STUDY TO CONFIRM OR EXCLUDE MDS IN PATIENTS WITH ANEMIA OF UNCERTAIN ETIOLOGY

Lopez Godino, O.; (...); Diez Campelo, M.

Meeting Abstract. 2015

  • Open Access.

HIDDEN MDS: A PROSPECTIVE STUDY TO CONFIRM OR EXCLUDE MDS IN PATIENTS WITH ANEMIA OF UNCERTAIN ETIOLOGY

Lopez-Godino, O.; (...); Diez Campelo, M.

Meeting Abstract. 10.1016/S0145-2126(15)30309-X. 2015


Home-delivered ultrasound monitoring for home treatment of haemarthrosis in haemophilia A

Aznar JA; (...); Bonanad S

Letter. 10.1111/hae.12622. 2015


Identification and validation of plasma micrornas involved in venous and arterial thrombosis

Ramon, L. A.; (...); Navarro, S.

Meeting Abstract. 2015


IDENTIFICATION OF 58 MUTATIONS (26 NEW) IN 94 OF 109 BEING TESTED WITH PROTEIN DEFICIENCY C. SETH WORKING GROUP

Fernandez-Pardo, A.; (...); Navarro, S.

Meeting Abstract. 2019

  • Open Access.

Identification of 58 Mutations (26 Novel) in 94 of 109 Symptomatic Spanish Probands with Protein C Deficiency

Martos, L; (...); Spanish Soc Thrombosis Haemostasis

Article. 10.1055/s-0039-1692440. 2019


IDENTIFICATION OF A PROFILE OF CLASSES OF CIRCULATING LIPIDS ASSOCIATED WITH THE VENOUS THROMBOEMBOLISM

Fernandez-Pardo, A.; (...); Navarro, S.

Meeting Abstract. 2019

  • Open Access.

Immune Tolerance Induction in A Patient with Severe Haemophilia A and Factor VIII Inhibitors

Freiria Alberte, C.; (...); Haya Guaita, S.

Meeting Abstract. 2017


IMPACT OF INITIATION OF PROPHYLAXIS, SYNOVITIS AND FUNCTIONALITY ON JOINT HEALTH IN PATIENTS WITH HEMOPHILIA

Chimeno, A.; (...); Bonanad Boix, S.

Meeting Abstract. 2023


Increase of Neutrophil Activation Markers in Venous Thrombosis-Contribution of Circulating Activated Protein C

Martos L; (...); Medina P

Article. 10.3390/ijms21165651. 2020

  • Open Access.

Increased circulating dna, calprotectin and mieloperoxidase, as neutrophil extracellular trap markers, are risk factors for deep vein thrombosis

Martos, L.; (...); Medina, P.

Meeting Abstract. 2015


INCREASED LEVELS OF FREE CIRCULATING DNA AND DNASE 1 ACTIVITY IN PLASMA IS ASSOCIATED WITH AN INCREASED RISK OF VENOUS THROMBOEMBOLISM

Oto, J.; (...); Medina, P.

Meeting Abstract. 2019

  • Open Access.

Individualization of prophylaxis with recombinant factor VIII in severe or moderate hemophilia A

Vericat, JEM; (...); Bonanad, S

Meeting Abstract. 2018


Individualized Prophylactic Treatment with Recombinant Factor VIII in Severe or Moderate Haemophilia a Patients. Association Between Pharmacokinetic Parameters and Clinical Variables

Megias-Vericat, Juan Eduardo; (...); Bonanad, Santiago

Meeting Abstract. 10.1182/blood.V128.22.3802.3802. 2016


Inhibitor development after switching of FVIII concentrate in multitransfused patients with severe haemophilia A

Aznar JA; (...); Bonanad S

Article. 10.1111/hae.12439. 2014


Joint status in Spanish haemophilia B patients assessed using the Haemophilia Early Arthropathy Detection with Ultrasound (HEAD-US) score.

Jiménez-Yuste V; (...); Kim HK

Article. 10.1111/hae.13628. 2019


Management of acquired hemophilia A: results from the Spanish registry.

Mingot-Castellano ME; (...); Marco P

Article. 10.1182/bloodadvances.2021004626. 2021

  • Open Access.

Management of flexible cavovarus foot in patients with Charcot-Marie-Tooth disease: midterm results.

Megías-Vericat JE; (...); Poveda-Andrés JL

Article. 2021

  • Open Access.

Management of Urgent Bleeding in Patients with Hemophilia A: Focus on the Use of Emicizumab.

Jiménez-Yuste V; (...); Rodríguez-López M

Article. 10.1055/s-0044-1785525. 2024

  • Open Access.

Matching-Adjusted Indirect Comparison of Efficacy and Consumption of rVIII-SingleChain Versus Two Recombinant FVIII Products Used for Prophylactic Treatment of Adults/Adolescents with Severe Haemophilia A

Bonanad, S; (...); Santos, S

Article. 10.1007/s12325-021-01853-0. 2021

  • Open Access.

Mental, emotional and social dimensions of quality of life and their relationship with physical and functional status in adults with haemophilia.

Rodríguez MA; (...); Chimeno-Hernández A

Article. 10.1016/j.thromres.2024.109181. 2024

  • Open Access.

Moderate and severe haemophilia in Spain: An epidemiological update

Aznar, JA; (...); Lopez, MF

Letter. 10.1111/hae.13462. 2018


Moderate haemophilia A: Recommendations from a Spanish panel of experts.

Álvarez Román MT; (...); López-Jaime FJ

Article. 10.1111/hae.15110. 2024

  • Open Access.

Modification of a thrombin generation test to identify new cofactors of the protein C pathway in plasma

Martos, L.; (...); Navarro, S.

Meeting Abstract. 2015


Molecular and clinical profile of von Willebrand disease in Spain (PCM-EVW-ES): comprehensive genetic analysis by next-generation sequencing of 480 patients

Borràs N; (...); Corrales, I

Article. 10.3324/haematol.2017.168765. 2017

  • Open Access.

Molecular and clinical profile of von Willebrand disease in Spain (PCM-EVW-ES): Proposal for a new diagnostic paradigm

Batlle J; (...); Vidal F

Article. 10.1160/TH15-04-0282. 2016


Monitoring coagulation factors during surgery. A systematic review

Eduardo Megias-Vericat, Juan; (...); Luis Poveda-Andres, Jose

Review. 10.7399/fh.11766. 2021


Monitoring drug activity of dabigatran and rivaroxaban by thrombin generation using the calibrated automated thrombinoscope

Moret, A.; (...); Bonanad, S.

Meeting Abstract. 2015


MONITORING OF THE JOINT HEALTH OF PATIENTS WITH HEMOPHILIA IN SPAIN. INITIAL ANALYSIS OF THE JOINT US PROJECT

Alvarez-Roman, MT; (...); Querol, F

Meeting Abstract. 2021


Multimodal exercises program to improve balance in patients with haemophilia: preliminary results

Chimeno-Hernandez, A; (...); Quero, F

Meeting Abstract. 2021


Multivariable time-dependent analysis of the impact of azacitidine in patients with lower-risk myelodysplastic syndrome and unfavorable specific lower-risk score

Falantes J; (...); Sanz G

Article. 10.1016/j.leukres.2014.10.004. 2015


Muscle strength in load-bearing joints in haemophilic patients: comparative values with the general population

Bonanad-Boix, S.; (...); Querol, F.

Meeting Abstract. 2015


Muscle Strength in Spanish Children with Mild and Severe Haemophilia A

Bonanad, S.; (...); Querol-Fuentes, F.

Meeting Abstract. 2016


National Survey on the Use of Mobile Applications in Patients with Hemophilia and Other Coagulopathies

Eduardo Megias, Juan; (...); Poveda Andres, Jose Luis

Meeting Abstract. 10.1182/blood-2022-169938. 2022

  • Open Access.

Neutrophil extracellular traps (NETs) in patients with STEMI. Association with percutaneous coronary intervention and antithrombotic treatments.

Ferre-Vallverdu, Mari; (...); Moscardo, Antonio

Article. 10.1016/j.thromres.2022.03.002. 2022


Next generation sequencing in bleeding disorders: two novel variants in the F5 gene (Valencia-1 and Valencia-2) associated with mild factor V deficiency.

Moret, A; (...); Bonanad, S

Article. 10.1007/s11239-019-01911-z. 2019


Novel investigations on the protective role of the FVIII/VWF complex in inhibitor development

Mannucci PM; (...); Klamroth R

Review. 10.1111/hae.12465. 2014


Novel investigations on the protective role of the FVIII/VWF complex in inhibitor development (vol 20, pg 2, 2014)

Mannucci, P. M.; (...); Klamroth, R.

Correction. 10.1111/hae.12510. 2014


Online course of pharmacokinetic monitoring in hemophilia with application in the clinical practice

Bonanad, S; (...); Poveda, JL

Meeting Abstract. 2018


Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) Treated with Pegcetacoplan: Real Life Experience

Vallejo, Carlos; (...); Vara, Miriam

Meeting Abstract. 10.1182/blood-2023-185570. 2023


Pharmacokinetic and clinical improvements after PK-guided switch from standard half-life to extended half-life factor VIII products.

Megias-Vericat, J. E.; (...); Poveda Andres, J. L.

Article. 10.1016/j.thromres.2022.06.001. 2022


Physical Activity in adult patient with haemophilic arthropathy monitored by Fitbit Charge HR

Perez-Alenda, Sofia; (...); Bonanad, Santiago

Meeting Abstract. 2016


Physical Activity In Haemophilia: Hemorrhagic Risk And Factor Levels (myPKFiT)

Querol-Fuentes, F; (...); Bonanad, S

Meeting Abstract. 2017


Physical Activity Monitoring and Acceptance of a Commercial Activity Tracker in Adult Patients with Haemophilia.

Carrasco JJ; (...); Querol F

Article. 10.3390/ijerph16203851. 2019

  • Open Access.

Pilot evaluation of home delivery programme in haemophilia

Megias-Vericat, JE; (...); Poveda-Andres, JL

Article. 10.1111/jcpt.12718. 2018


PK-GUIDED SWITCH BETWEEN STANDARD HALF-LIFE AND EXTENDED HALF-LIFE FACTOR VIII PRODUCTS

Vericat, JEM; (...); Iorio, A

Meeting Abstract. 2020


PK-guided switch from standard half-life to extended half-life factor VIII products

Megias-Vericat, JE; (...); Iorio, Alfonso

Meeting Abstract. 2020


Platelet function in malignant hematological disorders

Moscardó A; (...); Vallés J

Review. 10.1097/CCO.0000000000000237. 2015


Practical guide to emergency treatment of thrombotic microangiopathy

Romero S; (...); Grupo de Microangiopatía Trombótica del Hospital Universitario y Politécnico La

Editorial Material. 10.1016/j.medcli.2018.01.013. 2018


Predictive factors of immune tolerance treatment response in severe haemophilia A patients with inhibitors: A real-world report from a single centre, mixed retrospective-prospective long-term study

Haya, S; (...); Casana, P

Letter. 10.1111/hae.13660. 2019

  • Open Access.

PROPOSAL FOR A MULTIMODAL BALANCE EXERCISE PROGRAM FOR PEOPLE WITH HAEMOPHILIA

Chimeno-Hernandez, A; (...); Bonanad, S

Meeting Abstract. 2020


Quality of electronic treatment records and adherence to prophylaxis in haemophilia and von Willebrand disease: Systematic assessments from an electronic diary.

Tiede A; (...); Oldenburg J

Article. 10.1111/hae.14178. 2020

  • Open Access.

Quality of thawed plasma inactivated with methylene blue after 48-hour storage

Balaguer A; (...); Sanz MÁ

Letter. 10.1016/j.transci.2014.11.005. 2015


Quantification of physical activity in adult patients with haemophilic arthropathy in prophylaxis treatment using a fitness tracker

Perez-Alenda, S; (...); Querol, F

Letter. 10.1111/hae.13388. 2018


Radiosynoviorthesis in the Treatment of Recurrent Hemarthrosis in Patients with Haemophilia: Experience in a Single Center

Querol-Fuentes, F; (...); Bonanad, S

Meeting Abstract. 2017


Real-world analysis of the PK-guided switch from standard half-life factor VIII to efmoroctocog alfa.

Megias-Vericata, J. E.; (...); Poveda Andres, J L

Letter. 10.1016/j.thromres.2023.11.023. 2023


Real-world data in patients with congenital hemophilia and inhibitors: final data from the FEIBA Global Outcome (FEIBA GO) study.

Ettingshausen CE; (...); Windyga J

Article. 10.1177/20406207231184323. 2023

  • Open Access.

Remote monitorization of physical exercises for patients with hemophilia using kinect V2

Perez-Alenda, S; (...); Querol-Fuentes, F

Meeting Abstract. 2018


RETROSPECTIVE STUDY OF AZACITIDINE IN PATIENTS OF ADVANCED AGE WITH ACUTE MYELOID LEUKEMIA (LMA). RESULTS OF THE ALMA/ PETHEMA COHORT IN COMPARISON WITH THE MRC RISK INDEX SCORE

Falantes, J.; (...); Ramos, F.

Meeting Abstract. 2015

  • Open Access.

Role of multimeric analysis of von Willebrand factor (VWF) in von Willebrand disease (VWD) diagnosis: Lessons from the PCM-EVW-ES Spanish project

Perez-Rodriguez, A; (...); Lopez-Fernandez, MF

Article. 10.1371/journal.pone.0197876. 2018

  • Open Access.

Routine clinical care data for population pharmacokinetic modeling: the case for Fanhdi/Alphanate in hemophilia A patients

Chelle, P; (...); Edginton, A

Meeting Abstract. 2018


Routine clinical care data for population pharmacokinetic modeling: the case for Fanhdi/Alphanate in hemophilia A patients.

Chelle P; (...); Edginton A

Article. 10.1007/s10928-019-09637-4. 2019

  • Open Access.

Safety and Effectiveness of Progressive Moderate-to-Vigorous Intensity Elastic Resistance Training on Physical Function and Pain in People With Hemophilia.

Calatayud J; (...); Casaña J

Article. 10.1093/ptj/pzaa106. 2020


Signal transducer and activator of transcription 3 (STAT3) phosphorylation regulates thromboxane A 2 receptor activity in human platelets.

Latorre AM; (...); Moscardó A

Letter. 10.1111/bjh.16309. 2020

  • Open Access.

Source of Factor VIII Replacement (PLASMATIC OR RECOMBINANT) and Incidence of Inhibitory Alloantibodies in Previously Untreated Patients with Severe Hemophilia a: The Multicenter Randomized Sippet Study

Peyvandi, Flora; (...); Frits, Rosendaal R.

Meeting Abstract. 2015


Spanish consensus statement for diagnosis and treatment of paroxysmal nocturnal haemoglobinuria

Villegas A; (...); Urbano-Ispizua Á

Editorial Material. 10.1016/j.medcli.2015.12.012. 2016


Spanish Society of Hematology and Hemotherapy expert consensus opinion for SARS-CoV-2 vaccination in onco-hematological patients.

Pinana, JL; (...); Bosch F

Article. 10.1080/10428194.2021.1992619. 2021

  • Open Access.

Study of The Correlation Between Osteoporosis and Arthropathy in Haemophilia Patients Using Self-Organizing Maps

Querol-Fuentes, F.; (...); Bonanad, S.

Meeting Abstract. 2015


Suitability and readiness assessment of organizational resources for the implementation of gene therapy in hemophilia in Spain and Portugal: A survey-based study.

Villas JMC; (...); Álvarez-Román MT

Letter. 10.1016/j.thromres.2024.109180. 2024


Synoviorthesis in the Treatment of Recurrent Hemarthrosis in Haemophilia Patients with Inhibitors

Querol-Giner, M.; (...); Querol-Fuentes, F.

Meeting Abstract. 2016


The factor VIII treatment history of non-severe hemophilia A: COMMENT. Joint damage in adult patients with mild or moderate hemophilia A evaluated with the HEAD-US system

Roman, MTA; (...); Mosteirin, NF

Letter. 10.1111/jth.15475. 2021

  • Open Access.

The impact of progressive resistance training on physical function and quality of life in patients with haemophilia

Carrasco, JJ; (...); Querol-Fuentes, F

Meeting Abstract. 2019


The ISTH bleeding assessment tool as predictor of bleeding events in inherited platelet disorders: Communication from the ISTH SSC Subcommittee on Platelet Physiology

Gresele, P; (...); BAT-VAL Study Investigators

Article. 10.1111/jth.15263. 2021

  • Open Access.

The Limitations and Unmet Needs of the Five Cornerstones to Guarantee Lifelong Optimization of Prophylaxis in Hemophilia Patients.

Nunez, Ramiro; (...); Jimenez-Yuste, Victor

Article. 10.1055/s-0042-1757745. 2022

  • Open Access.

The safety of activated eptacog beta in the management of bleeding episodes and perioperative haemostasis in adult and paediatric haemophilia patients with inhibitors.

Escobar, M; (...); Kessler, C

Article. 10.1111/hae.14419. 2021

  • Open Access.

Thromboembolic hazard in hereditary hemorrhagic telangiectasia.

Asensi Canto, Pedro; (...); Bonanad Boix, Santiago

Article. 10.1002/jha2.471. 2022


Thrombotic risk and features of patients with inferior vena cava agenesis: a multicentre, retrospective, observational study.

Bravo-Perez, Carlos; (...); Corral, Javier

Article. 10.1016/S2352-3026(24)00138-8. 2024


Tolerability of knee and ankle exercises with machines and elastic resistance in patients with severe hemophilia

Perez-Alenda, S; (...); Bonanad, S

Meeting Abstract. 2018


Type 2N VWD: Conclusions from the Spanish PCM-EVW-ES project

Perez-Rodriguez, Almudena; (...); Lopez-Fernandez, Maria Fernanda

Article. 10.1111/hae.14405. 2021


Ultrasound evaluation of joint damage and disease activity in adult patients with severe haemophilia A using the HEAD-US system.

Jiménez-Yuste V; (...); Kim HK

Article. 10.1111/hae.14280. 2021


Ultrasound Protocol for the Diagnosis and Monitoring of the Acute Hemarthrosis

Querol-Fuentes, F.; (...); Bonanad, S.

Meeting Abstract. 2016


Unraveling the effect of silent, intronic and missense mutations on VWF splicing: contribution of next generation sequencing in the study of mRNA

Borras, N; (...); Corrales, I

Article. 10.3324/haematol.2018.203166. 2019

  • Open Access.

Unraveling the Influence of Common von Willebrand factor variants on von Willebrand Disease Phenotype: An Exploratory Study on the Molecular and Clinical Profile of von Willebrand Disease in Spain Cohort

Borras, N; (...); Vidal, F

Article. 10.1055/s-0040-1702227. 2020


Update on Molecular Testing in von Willebrand Disease

Batlle, J; (...); PCM-EVW-ES Investigators Team

Review. 10.1055/s-0039-1679922. 2019


Upper-Body Exercises With External Resistance Are Well Tolerated and Enhance Muscle Activity in People With Hemophilia

Calatayud, J; (...); Casana, J

Article. 10.1093/ptj/pzy136. 2019

  • Open Access.

Usability and usefulness of a wearable activity tracker in patients with hemophilia

Querol-Fuentes, F; (...); Bonanad, S

Meeting Abstract. 2018


Validity of a depth camera for elbow range of motion measurement in haemophilic patients: The first step for a telemedicine approach

Mateo, F; (...); Querol-Fuentes, F

Meeting Abstract. 2018


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