Human organoids to model the healthy female reproductive tract using native bioengineering supports and their pre-clinical applications in the gynecologycal medicine field (Organoides humanos para modelar el tracto reproductivo femenino sano mediante soportes nativos de bioingeniería y sus aplicaciones preclínicas en el campo de la medicina ginecológica).

Article. 10.1016/j.bioadv.2023.213480. 2023

Bioengineering an Ovarian-Specific ECM Hydrogel to Treat Premature Ovarian Failure

Meeting Abstract. 2023

Bioengineering trends in female reproduction: a systematic review

Frances-Herrero, Emilio; (...); Cervello, Irene

Review. 10.1093/humupd/dmac025. 2022

Biotechnological progresses in modelling the human endometrium: the evolution of current in vitro techniques and emerging trends.

Agustina-Hernandez, Marcos; (...); Cervello, Irene

Article. 10.3389/fbioe.2024.1495338. 2024

Correction to: Impact of Endometrial Receptivity Analysis on Pregnancy Outcomes In Patients Undergoing Embryo Transfer: A Systematic Review and Meta-Analysis.

Zolfaroli, Irene; (...); Rubio, Jose Maria Rubio

Correction. 10.1007/s10815-023-02808-w. 2023

Deciphering the Role of Histone Modifications in Uterine Leiomyoma: Acetylation of H3K27 Regulates the Expression of Genes Involved in Proliferation, Cell Signaling, Cell Transport, Angiogenesis and Extracellular Matrix Formation.

Carbajo-Garcia, Maria Cristina; (...); Ferrero, Hortensia

Article. 10.3390/biomedicines10061279. 2022

Deciphering the role of PGRMC2 in the human endometrium during the menstrual cycle and in vitro decidualization using an in vitro approach.

Medina-Laver Y; (...); Dominguez F

Article. 10.1093/humrep/deae044. 2024

EFFECT OF HUMAN UMBILICAL CORD BLOOD PLATELET-RICH PLASMA COMBINED WITH EXTRACELLULAR MATRIX HYDROGELS ON IMMUNOCOMPETENT ENDOMETRIAL DAMAGE: MURINE MODELS

Rodriguez Eguren, Adolfo; (...); Cervello, Irene

Meeting Abstract. 2022

Effects of In Vitro Culture Systems with Fallopian Tube Extracellular Matrix on Rabbit Embryo Gene Expression.

Meeting Abstract. 2024

Endometrial Extracellular Matrix Hydrogel Alleviates Epithelial-toMesenchymal Transition Triggered by Human Umbilical Cord PlateletRich Plasma in Human Endometrial Organoids.

Meeting Abstract. 2024

Endometrial Extracellular Matrix Hydrogels as Alternatives to Matrigel for Culturing Human Endometrial Organoids

Gomez-Alvarez, Maria; (...); Cervello, Irene

Meeting Abstract. 2023

Endometrial extracellular vesicles regulate processes related to embryo development and implantation in human blastocysts

Segura-Benitez, Marina; (...); Ferrero, Hortensia

Article. 10.1093/humrep/deae256. 2024

Enhancing Development of Murine Follicles In Vitro Using Extracellular Matrix from Decellularized Bovine Ovarian Cortex

Meeting Abstract. 2022

EPITHELIAL-TO-MESENCHYMAL TRANSITION INDUCTION BY HUMAN UMBILICAL CORD PLATELET-RICH PLASMA IN HUMAN ENDOMETRIAL ORGANOIDS: DIFFERENTIATION STATE MATTERS

Agustina-Hernandez, Marcos; (...); Cervello, Irene

Meeting Abstract. 10.1016/j.fertnstert.2024.07.263. 2024

Establishment of Adenomyosis Organoids as a Preclinical Model to Study Infertility.

Article. 10.3390/jpm12020219. 2022

Evolution of biotechnological advances and regenerative therapies for endometrial disorders: a systematic review.

Article. 10.1093/humupd/dmae013. 2024

EXTRACELLULAR VESICLES SECRETED BY ENDOMETRIAL ORGANOIDS FROM ADENOMYOSIS PATIENTS CONTAIN MIRNAS IMPLICATED IN DISEASE DEVELOPMENT, EMBRYO IMPLANTATION FAILURE AND PREGNANCY DISORDERS

Meeting Abstract. 2022

Fallopian tube extracellular matrix hydrogels for in vitro embryo culture in rabbit models: A post-natal study

Frances, E.; (...); Cervello, I.

Meeting Abstract. 2022

Frasier syndrome: A case report

Trelis-Blanes, A.; (...); Monzo-Miralles, A. M.

Article. 10.1016/j.gine.2022.100827. 2023

Future Challenges and Opportunities of Extracellular Matrix Hydrogels in Female Reproductive Medicine

Francés-Herrero E; (...); Cervelló I

Article. 10.3390/ijms23073765. 2022

Generation of Complex 3D Human Endometrial Assembloids with Epithelial Organoids and Stromal Stem Cell Lines.

Meeting Abstract. 2022

GLOBAL DELETION OF MITOCHONDRIAL PINK1 GENE INDUCES LOSS OF FOLLICULAR RESERVE AND PRODUCES FEMALE INFERTILITY

Rodriguez Eguren, Adolfo; (...); Seli, Emre

Meeting Abstract. 2023

Growth Factor-Enriched Xenogeneic Ovarian ECM Hydrogels: A Promising Treatment for Premature Ovarian Failure.

Meeting Abstract. 2024

Growth factor-loaded ovarian extracellular matrix hydrogels promote in vivo ovarian niche regeneration and enhance fertility in premature ovarian insufficiency preclinical models.

Article. 10.1016/j.actbio.2024.07.056. 2024

H3K4me3 mediates uterine leiomyoma pathogenesis via neuronal processes, synapsis components, proliferation, and Wnt/beta-catenin and TGF-beta pathways.

Carbajo-García MC; (...); Ferrero, Hortensia

Article. 10.1186/s12958-023-01060-2. 2023

Human Adenomyosis Endometrial Organoids Recapitulate Disease Pathological Features and Show Dysregulated Expression of Implantation and Placentation Biomarkers

Juarez-Barber, Elena; (...); Ferrero, Hortensia

Meeting Abstract. 2022

Human blastocysts uptake extracellular vesicles secreted by endometrial cells containing miRNAs related to implantation.

Segura-Benítez M; (...); Ferrero H

Article. 10.1093/humrep/dead138. 2023

HUMAN BLASTOCYSTS UPTAKE EXTRACELLULAR VESICLES SECRETED BY PRIMARY ENDOMETRIAL EPITHELIAL CELLS CONTAINING MIRNAS RELATED TO IMPLANTATION AND EARLY EMBRYO DEVELOPMENT

Segura-Benitez, Marina; (...); Ferrero, Hortensia

Meeting Abstract. 2022

Human endometrial organoids embedded in hybrid endometrial-derived hydrogels as a biocompatible treatment for endometrial pathologies in preclinical models

Gomez-Alvarez, M.; (...); Cervello, I.

Meeting Abstract. https://doi.org/10.1093/humrep/deae108.1104. 2024

Human umbilical cord platelet-rich plasma to treat endometrial pathologies: methodology, composition and pre-clinical models.

Article. 10.1093/hropen/hoac053. 2023

Human Umbilical Cord Platelet-Rich Plasma: Metabolomic, Proteomic, and Wound Healing Studies in Endometrial Stem Cells.

Bueno-Fernandez, Clara; (...); Cervello, Irene

Meeting Abstract. 2024

Human Umbilical Cord-Based Therapeutics: Stem Cells and Blood Derivatives for Female Reproductive Medicine

Review. 10.3390/ijms232415942. 2022

Hybrid Endometrial-Derived Hydrogels: Human Organoid Culture Models and In Vivo Perspectives.

Gomez-alvarez, Maria; (...); Cervello, Irene

Article. 10.1002/adhm.202303838. 2023

Impact of prolonged embryo storage on reproductive and neonatal outcomes: a systematic review and meta-analysis.

Zolfaroli I; (...); Monzó Miralles A

Article. 10.1007/s10815-024-03283-7. 2024

MITOPHAGY-REGULATING GENE PARKIN IS REQUIRED FOR FEMALE FERTILITY

Eguren, Adolfo Rodriguez; (...); Seli, Emre

Meeting Abstract. 2023

Murine Oocyte Maturation and Developmental Competence Using Biocompatible Hydrogel Based on Decellularized Bovine Ovarian Cortex

Lopez, Rosalba; (...); Cervello, Irene

Meeting Abstract. 2022

Oviductal extracellular matrix hydrogels enhance in vitro culture of rabbit embryos and reduce deficiencies during assisted reproductive technologies

Article. 10.1038/s41598-024-77583-4. 2024

Predicted COVID-19 molecular effects on endometrium reveal key dysregulated genes and functions

Henarejos-Castillo, I; (...); Diaz-Gimeno, P.

Article. 10.1093/molehr/gaac035. 2022

Role of Endometrial Extracellular Vesicles miRNAs as Potential Autocrine Regulators of Gene Expression During Embryo Implantation Process in Adenomyosis.

Meeting Abstract. 2024

Standard-dose Vitamin D supplementation as an effective and safe non-hormonal treatment for the prevention of uterine fibroid growth in reproductive-age women: A pilot study

Orive, A.; (...); Ferrero, H.

Meeting Abstract. 2023

The Effects of Platelet-Rich Plasma Derived from Human Umbilical Cord Blood in Human Endometrial Organoids

Gomez-Alvarez, Maria; (...); Cervello, Irene

Meeting Abstract. 2023

Transcriptome analysis of adenomyosis eutopic endometrium reveals molecular mechanisms involved in adenomyosis-related implantation failure and pregnancy disorders.

Article. 10.1186/s12958-023-01182-7. 2024

Transcriptomic Analysis of Adenomyosis Mid-Secretory Endometrial Organoids Reveals Deregulated Molecular Mechanisms Involved in Implantation Failure and Pregnancy Loss