Senescencia celular cerebral como condición asociada al envejecimiento que agrava el daño cerebral inducido por ictus: una oportunidad para los fármacos senolíticos.

Datos básicos

Código:
PID2020-119603RB-I00
Protocolo:
PID2020-119603RB-I00
EUDRACT:
NCT:
Centro:
Dotación:
133.100,00 €
Año de incio:
2021
Año de finalización:
2025
PI BIOMÉDICA NACIONAL Finan. Competitiva Pública

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Participantes

Grupos

Financiadores - Promotores

MINISTERIO DE CIENCIA E INNOVACION

Resultados del Ensayo Clínico


Automatic etiological classification of stroke thrombus digital photographs using a deep learning model

Lucero-Garofano, Alvaro; (...); Manjon, Jose V.

Article. 10.3389/fneur.2025.1534845. 2025

  • Open Access.

Brain Cell Senescence: A New Therapeutic Target for the Acute Treatment of Ischemic Stroke

Baixauli-Martin, Julia; (...); Salom, Juan B.

Article. 10.1093/jnen/nlac048. 2022


Bull Sperm SWATH-MS-Based Proteomics Reveals Link between High Fertility and Energy Production, Motility Structures, and Sperm-Oocyte Interaction.

Gacem, Sabrina; (...); Silvestre, Miguel A

Article. 10.1021/acs.jproteome.3c00461. 2023


Cerebroprotective Effect of 17beta-Estradiol Replacement Therapy in Ovariectomy-Induced Post-Menopausal Rats Subjected to Ischemic Stroke: Role of MAPK/ERK1/2 Pathway and PI3K-Independent Akt Activation.

Burguete, Maria C.; (...); Salom, Juan B.

Article. 10.3390/ijms241814303. 2023

  • Open Access.

Cerebroprotective Effects of the TLR4-Binding DNA Aptamer ApTOLL in a Rat Model of Ischemic Stroke and Thrombectomy Recanalization

Aliena-Valero, Alicia; (...); Salom, Juan B.

Article. 10.3390/pharmaceutics16060741. 2024

  • Open Access.

Clot Composition Analysis as a Diagnostic Tool to Gain Insight into Ischemic Stroke Etiology: A Systematic Review

Aliena-Valero, Alicia; (...); Salom, Juan B.

Article. 10.5853/jos.2021.02306. 2021

  • Open Access.

Cyto-Neurology in Ischemia.

Roque, Claudio, Burguete, Maria C.

Article. 10.31083/j.jin2105136. 2022

  • Open Access.

Effect and mechanisms of resveratrol in animal models of ischemic stroke: A systematic review and Bayesian meta-analysis.

Lopez-Morales, Mikahela A; (...); Salom, Juan B

Article. 10.1177/0271678X231206236. 2023


Functional Recovery and Serum Angiogenin Changes According to Intensity of Rehabilitation Therapy After Stroke.

Garcia-Rodriguez N; (...); Rosell A

Article. 10.3389/fneur.2021.767484. 2021

  • Open Access.

Intravenous SPION-labeled adipocyte-derived stem cells targeted to the brain by magnetic attraction in a rat stroke model: An ultrastructural insight into cell fate within the brain.

García-Belda P; (...); Gil-Perotín S

Article. 10.1016/j.nano.2021.102464. 2021


Preclinical Characterization of Antioxidant Quinolyl Nitrone QN23 as a New Candidate for the Treatment of Ischemic Stroke

Martinez-Alonso, Emma; (...); Alcazar, Alberto

Article. 10.3390/antiox11061186. 2022

  • Open Access.

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